Raspberry ketone glucoside

Name: Raspberry ketone glucoside
Brand: MedChemExpress
SKU: HY-N6069
Rating: 4.5 (1 reviews)

Cat. No.: HY-N6069 Purity: 99.52%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Raspberry ketone glucoside is a natural product in raspberry fruit. Raspberry ketone glucosidev has the inhibitory effect on the melanin synthesis.

For research use only. We do not sell to patients.

Raspberry ketone glucoside Chemical Structure

CAS No. : 38963-94-9

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Customer Review

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE Raspberry ketone glucoside

•J Agric Food Chem. 2023 Sep 1. [Abstract]

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Raspberry ketone glucoside is a natural product in raspberry fruit. Raspberry ketone glucosidev has the inhibitory effect on the melanin synthesis^[1].

Molecular Weight

326.34

Formula

C₁₆H₂₂O₇

CAS No.

38963-94-9

Appearance

Solid

Color

White to off-white

SMILES

CC(CCC(C=C1)=CC=C1O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (153.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0643 mL	15.3214 mL	30.6429 mL
5 mM	0.6129 mL	3.0643 mL	6.1286 mL
10 mM	0.3064 mL	1.5321 mL	3.0643 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (7.66 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (7.66 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.
Protocol 3

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.72 mg/mL (5.27 mM); Clear solution

This protocol yields a clear solution of ≥ 1.72 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (17.2 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.52%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (247 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Tomohiro Yokota, et al. Lasting Effect of Raspberry Ketone Glucoside on Whitening. Liebigs Annalen. 2017, Vol.2017, No.48, p.7295.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0643 mL	15.3214 mL	30.6429 mL	76.6072 mL
	5 mM	0.6129 mL	3.0643 mL	6.1286 mL	15.3214 mL
	10 mM	0.3064 mL	1.5321 mL	3.0643 mL	7.6607 mL
	15 mM	0.2043 mL	1.0214 mL	2.0429 mL	5.1071 mL
	20 mM	0.1532 mL	0.7661 mL	1.5321 mL	3.8304 mL
	25 mM	0.1226 mL	0.6129 mL	1.2257 mL	3.0643 mL
	30 mM	0.1021 mL	0.5107 mL	1.0214 mL	2.5536 mL
	40 mM	0.0766 mL	0.3830 mL	0.7661 mL	1.9152 mL
	50 mM	0.0613 mL	0.3064 mL	0.6129 mL	1.5321 mL
	60 mM	0.0511 mL	0.2554 mL	0.5107 mL	1.2768 mL
	80 mM	0.0383 mL	0.1915 mL	0.3830 mL	0.9576 mL
	100 mM	0.0306 mL	0.1532 mL	0.3064 mL	0.7661 mL