CALCB Protein, Human (HEK293, mFc)

CALCB, known for its vasodilatory effects, induces dilation in various vessels, encompassing the coronary, cerebral, and systemic vasculature. Its notable abundance in the central nervous system suggests a potential role as a neurotransmitter or neuromodulator, underscoring its significance in physiological processes related to vascular regulation and neural signaling. CALCB Protein, Human (HEK293, mFc) is the recombinant human-derived CALCB protein, expressed by HEK293 , with C-mFc labeled tag.

CALCB (Calcitonin gene-related peptide beta) protein, also known as CGRP (Calcitonin Gene-Related Peptide), is a neuropeptide that plays a crucial role in inducing vasodilation. CGRP exerts its vasodilatory effects on various vessels, including those in the coronary, cerebral, and systemic vasculature. This ability to promote dilation suggests its involvement in regulating blood flow and vascular tone. Additionally, the abundance of CGRP in the central nervous system (CNS) hints at its potential roles as a neurotransmitter or neuromodulator, emphasizing its significance in neural signaling and modulation within the CNS.

Human

HEK293

C-mFc

P10092 (A26-F118)

797  [NCBI]

Approximately 37 kDa

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.