2. Anti-infection
  3. Bacterial Antibiotic
  4. (S)-Ofloxacin-d3

(S)-Ofloxacin-d3 is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

For research use only. We do not sell to patients.

(S)-Ofloxacin-d<sub>3</sub> Chemical Structure

(S)-Ofloxacin-d3 Chemical Structure

CAS No. : 2208780-63-4

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1 mg USD 630 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of (S)-Ofloxacin-d3:

(S)-Ofloxacin-d3 Related Antibodies

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Description

(S)-Ofloxacin-d3 is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(S)-Ofloxacin-d3 Related Antibodies
Molecular Weight

364.39

Formula

C18H17D3FN3O4
CAS No.
Unlabeled CAS

100986-85-4
Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=CC(F)=C(N3CCN(CC3)C([2H])([2H])[2H])C4=C2N(C=C1C(O)=O)[C@@H](C)CO4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (27.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 5 mg/mL (13.72 mM)

H2O : ≥ 5 mg/mL (13.72 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7443 mL 13.7216 mL 27.4431 mL
5 mM 0.5489 mL 2.7443 mL 5.4886 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

SDS (251 KB)

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O / DMSO 1 mM 2.7443 mL 13.7216 mL 27.4431 mL 68.6078 mL
5 mM 0.5489 mL 2.7443 mL 5.4886 mL 13.7216 mL
10 mM 0.2744 mL 1.3722 mL 2.7443 mL 6.8608 mL
DMSO 15 mM 0.1830 mL 0.9148 mL 1.8295 mL 4.5739 mL
20 mM 0.1372 mL 0.6861 mL 1.3722 mL 3.4304 mL
25 mM 0.1098 mL 0.5489 mL 1.0977 mL 2.7443 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(S)-Ofloxacin-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Ofloxacin-d32208780-63-4BacterialAntibioticInhibitorinhibitorinhibit

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