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( )-Oxypeucedanin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (2) Bacterial (1) COX (1) ERK (1) JNK (1) NF-κB (1) NO Synthase (1) p38 MAPK (1) PI3K (1) Potassium Channel (2) Prostaglandin Receptor (1) ROS Kinase (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (2)

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3

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Oxypeucedanin*	Potassium Channel PI3K NF-κB Akt p38 MAPK ERK COX NO Synthase JNK Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Oxypeucedanin is a furanocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a PI3K/AKT/NF-κB, MAPK and ROS inhibitor. Oxypeucedanin induces cell cycle arrest and apoptosis. Oxypeucedanin inhibits hKv1.5 channel currents (IC₅₀: 76 nM). Oxypeucedanin exhibits anticancer, anti-inflammatory, antioxidant and antiarrhythmic activities .

Oxypeucedanin hydrate (+)-Oxypeucedanin hydrate	Others	Cancer
Oxypeucedanin hydrate ((+)-Oxypeucedanin hydrate) is a natural product isolated from D. anethifolia. Prangol exhibits mild toxicity on fibroblasts and parental lymphoma cells .

*(-)-Oxypeucedanin* hydrate** (-)-Prangol	Others	Cancer
(-)-Oxypeucedanin hydrate ((-)-Prangol) is a derivative of furocoumarin isolated from Ducrosia anethifolia .

Oxypeucedanin (Standard)	Potassium Channel Apoptosis	Cardiovascular Disease Cancer
Oxypeucedanin (Standard) is the analytical standard of Oxypeucedanin. This product is intended for research and analytical applications. Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC₅₀ value of 76 nM.?Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation . Oxypeucedanin induces cell?apoptosis through inhibition of cancer cell migration .

Iso-oxypeucedanin	Others	Others
Iso-oxypeucedanin is a coumarin found in Angelica dahurica.

*(+)-Oxypeucedanin* methanolate**	Prostaglandin Receptor	Inflammation/Immunology
(+)-Oxypeucedanin methanolate (compound 9) is a natural compound with inhibitory effect on prostaglandin E2 production .

HS-291	ROS Kinase Bacterial	Infection
HS-291 is a HtpG inhibitor of Borrelia burgdorferi (Bb). HS-291 contains BX-2819 (high affinity for Bb HtpG), PEG linker, and Verteporfin (HY-B0146) (a photoactive toxin).HS-291 produces reactive oxygen species under light activation to oxidize HtpG and a discrete protein subset near chaperone proteins and can quickly and irreversibly inactivate Bb .

Species:	Virus (2) Human (1)
Tag:	His (2) GST (1)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	NS3 protease Protein, HCV (GST) Hepatitis C virus (HCV-1a) NS3 protease / helicase immunodominant region Protein ( GST)	Virus	E. coli
	NS3 protease Protein is a zinc-dependent serine protease.NS3 needs to bind to the viral protein NS4A to enable additional conformation changes that enhance activity and appropriate intracellular localization.NS3 protein induces Caspase-8-mediated apoptosis independently of its protease or helicase activity.NS3 protease Protein, HCV (GST) is the recombinant Virus-derived NS3 protease protein, expressed by E.coli , with N-GST labeled tag.

	VSTM2A Protein, Human ( E84K, HEK293, His) V-set and transmembrane domain-containing protein 2A; VSTM2	Human	HEK293
	The VSTM2A protein is a key player in early white and brown preadipocyte differentiation and actively promotes adipogenesis by upregulating the transcription factor PPARG. This regulation operates in BMP4-dependent signaling pathways, highlighting the complex molecular mechanisms involved in differentiation. VSTM2A Protein, Human ( E84K, HEK293, His) is the recombinant human-derived VSTM2A protein, expressed by HEK293 , with C-6*His labeled tag and E84K mutation.

	HA/Hemagglutinin Protein, H3N2 ( EPI189220, sf9, His) Influenza A H3N2 (A/Victoria/208/2009) Hemagglutinin / HA Protein (sf9, His)	Virus	Sf9 insect cells
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways. As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane. HA/Hemagglutinin Protein, H3N2 ( EPI189220, sf9, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by Sf9 insect cells , with C-His labeled tag.

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