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Results for "

1O2

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Fluorescent Dye

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0185
    2'-Deoxyguanosine monohydrate
    4 Publications Verification

    		 Endogenous Metabolite Metabolic Disease
    2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .
    2'-Deoxyguanosine monohydrate
  • HY-145538
    2'-Deoxyguanosine 5'-monophosphate disodium hydrate

    5'-Deoxyguanylic acid disodium hydrate

    		 DNA/RNA Synthesis Others
    2'-Deoxyguanosine 5'-monophosphate (5'-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism) .
    2'-Deoxyguanosine 5'-monophosphate disodium hydrate
  • HY-130027
    HKOCl-4
    1 Publications Verification

    BXY2142

    		 Fluorescent Dye Others
    HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.
    HKOCl-4
  • HY-153770
    DHPN

    		Biochemical Assay Reagents Others
    DHPN is a reversible carrier of singlet oxygen ( 1O2) and can be used as a chemical and physical quencher of 1O2 .
    DHPN
  • HY-159485
    NFh-ALP

    		Phosphatase Cancer
    NFh-ALP is an alkaline phosphatase (ALP)-activatable photosensitizer. NFh-ALP could be activated by ALP in cells and generate 1O2 under 808 nm excitation, effectively killing tumor cells by inducing apoptosis and having good biocompatibility. The maximum absorption wavelength of NFh-ALP is about 656 nm .
    NFh-ALP
  • HY-126841
    5-Methoxysterigmatocystin

    		Photosensitizer Cancer
    5-Methoxysterigmatocystin is a mycotoxin with cytotoxic and genotoxic properties. 5-Methoxysterigmatocystin exhibits cytotoxicity against cancer cells A549 and HepG2 (IC50 of 5.5 and 0.7 μM), and induces DNA damage. 5-Methoxysterigmatocystin is a photosensitizer, which utilizes the visible to generate singlet oxygen ( 1O2) .
    5-Methoxysterigmatocystin

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