Search Result
Results for "
5'-deoxy-thymidine
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
10
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-124425
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Antibiotic
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Cancer
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5′-Deoxythymidine is a thymidine form which 5' position replaced with hydrogen. 5'-deoxy Thymidine is effective against Bacillus subtilis and Staphylococcus aureus. 5′-Deoxythymidine can be used as a research tool for antiviral and anticancer studies .
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- HY-W013715A
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- HY-154348
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Nucleoside Antimetabolite/Analog
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Cancer
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4’,5’-Didehydro-5’-deoxy thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-138615
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- HY-138615A
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- HY-154740R
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Nucleoside Antimetabolite/Analog
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Cancer
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3′-Chloro-3′-deoxythymidine (Standard) is the analytical standard of 3′-Chloro-3′-deoxythymidine. This product is intended for research and analytical applications. 3′-Chloro-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-149160
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Nucleoside Antimetabolite/Analog
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Cancer
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5′-Amino-5′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154087
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Nucleoside Antimetabolite/Analog
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Cancer
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3′-Bromo-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154740
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Nucleoside Antimetabolite/Analog
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Cancer
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3′-Chloro-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154697
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Nucleoside Antimetabolite/Analog
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Cancer
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3-epi-Azido-3-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-138615S1
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- HY-138615S2
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- HY-138615S3
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- HY-116364
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3'-Azido-3'-deoxythymidine-5'-triphosphate
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HIV
DNA/RNA Synthesis
HBV
Reactive Oxygen Species
Apoptosis
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Infection
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AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate also inhibits the DNA polymerase of HBV. AZT triphosphate activates the mitochondria-mediated apoptosis pathway .
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- HY-B1516
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3'-Fluoro-3'-deoxythymidine; 3′-deoxy-3′-fluorothymidine; FLT
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DNA/RNA Synthesis
Orthopoxvirus
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Infection
Cancer
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Alovudine (3'-Fluoro-3'-deoxythymidine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus activity .
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- HY-138615S4
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- HY-137522A
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3'-Azido-3'-deoxythymidine β-D-glucuronide
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Drug Metabolite
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Others
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Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection .
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- HY-116364A
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3'-Azido-3'-deoxythymidine-5'-triphosphate TEA
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HIV
DNA/RNA Synthesis
HBV
Reactive Oxygen Species
Apoptosis
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Infection
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AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) TEA is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TEA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TEA also inhibits the DNA polymerase of HBV. AZT triphosphate TEA activates the mitochondria-mediated apoptosis pathway .
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- HY-116364B
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3'-Azido-3'-deoxythymidine-5'-triphosphate tetraammonium
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HIV
DNA/RNA Synthesis
HBV
Reactive Oxygen Species
Apoptosis
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Infection
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AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) tetraammonium is an active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate tetraammonium exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate tetraammonium also inhibits the DNA polymerase of HBV. AZT triphosphate tetraammonium activates the mitochondria-mediated apoptosis pathway .
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- HY-137522S
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3'-Azido-3'-deoxythymidine β-D-glucuronide-d3 sodium
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Isotope-Labeled Compounds
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Others
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Zidovudine O-β-D-glucuronide-d3 (sodium) (3'-Azido-3'-deoxythymidine β-D-glucuronide-d3 (sodium)) is a deuterium labeled Zidovudine O-β-D-glucuronide (sodium) (HY-137522). Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection .
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- HY-137522
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3'-Azido-3'-deoxythymidine β-D-glucuronide sodium
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Drug Metabolite
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Others
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Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection . Zidovudine O-β-D-glucuronide (sodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-115581
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deoxythymidine 3′,5′-diphosphate; pdTp
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Apoptosis
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Cancer
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Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3',5'-disphosphate exhibits anti-tumor efficacy in vivo .
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- HY-115581A
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deoxythymidine 3′,5′-diphosphate tetrasodium; pdTp tetrasodium
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Apoptosis
MicroRNA
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Cancer
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Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium is a selective inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the MicroRNA regulatory complex RISC subunit) and [3,5- 2H2] tyrosyl nuclease. Thymidine 3',5'-diphosphate tetrasodium has anti-tumor activity and can also be used as a catalyst in biochemical reactions .
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- HY-128710
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2'-deoxy-2'-fluoro-5-Methyluridine
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Others
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Cancer
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2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2) .
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- HY-W011142
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Endogenous Metabolite
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Metabolic Disease
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2'-Deoxyuridine 5'-monophosphate disodium is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .
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- HY-W040329
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Endogenous Metabolite
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Others
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2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-116364C
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3'-Azido-3'-deoxythymidine-5'-triphosphate sodium
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Others
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AZT triphosphate sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-W040329R
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Endogenous Metabolite
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Others
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2'-Deoxyadenosine (Standard) is the analytical standard of 2'-Deoxyadenosine. This product is intended for research and analytical applications. 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-W040329S2
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- HY-W040329S1
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- HY-W040329S
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- HY-W040329S3
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- HY-W751961
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- HY-P5443
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Bacterial
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Others
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Pyrrhocoricin is a biological active peptide. (Antimicrobial activity against Gram-negative bacteria)
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- HY-W552257
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Others
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Others
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Hydroxypyruvic acid phosphate serves as a crucial metabolic intermediate in the biosynthesis of L-Serine, being formed from the conversion of the glycolytic intermediate 3-phosphoglycerate through the action of 3-phosphoglycerate dehydrogenase. Subsequently, it is transformed into phosphoserine by phosphohydroxypyruvate aminotransferase, and finally, via the action of phosphoserine phosphatase, it is converted into L-Serine. This pathway not only highlights the significance of hydroxypyruvic acid phosphate in cellular proliferation but also emphasizes its role in providing essential one-carbon groups necessary for the synthesis of purine nucleotides and deoxythymidine monophosphate, thereby underscoring its metabolic importance in the central nervous system and various physiological conditions.
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Cat. No. |
Product Name |
Type |
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- HY-W013715A
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dTTP trisodium
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Gene Sequencing and Synthesis
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Deoxythymidine-5'-triphosphate (dTTP) trisodium is one of the four nucleoside triphosphates used in the synthesis of DNA .
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- HY-116364C
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3'-Azido-3'-deoxythymidine-5'-triphosphate sodium
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Gene Sequencing and Synthesis
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AZT triphosphate sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P5443
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Bacterial
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Others
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Pyrrhocoricin is a biological active peptide. (Antimicrobial activity against Gram-negative bacteria)
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-138615S1
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Deoxythymidine-5'-triphosphate- 15N2 (dTTP- 15N2) dilithium is 15N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138615S2
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Deoxythymidine-5'-triphosphate- 13C10 (dTTP- 13C10) dilithium is 13C-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-W040329S1
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2'-Deoxyadenosine- 13C10 is 13C-labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-138615S3
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Deoxythymidine-5'-triphosphate- 15N2,d15 (dTTP- 15N2,d15) dilithium is deuterium and 15N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138615S4
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Deoxythymidine-5'-triphosphate- 13C10, 15N2 (dTTP- 13C10, 15N2) dilithium is 13C and 15N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-137522S
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Zidovudine O-β-D-glucuronide-d3 (sodium) (3'-Azido-3'-deoxythymidine β-D-glucuronide-d3 (sodium)) is a deuterium labeled Zidovudine O-β-D-glucuronide (sodium) (HY-137522). Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection .
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- HY-W040329S2
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2'-Deoxyadenosine-d13 is deuterium labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-W040329S
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2'-Deoxyadenosine- 13C10, 15N5 is 13C and 15N-labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-W040329S3
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2'-Deoxyadenosine- 15N5,d13 is deuterium and 15N labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-W751961
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2'-Deoxyadenosine-15N5 is the 15N5-labeled version of 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative that can pair with deoxythymidine in double-stranded DNA.
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Cat. No. |
Product Name |
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Classification |
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- HY-137522
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3'-Azido-3'-deoxythymidine β-D-glucuronide sodium
|
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Azide
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Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection . Zidovudine O-β-D-glucuronide (sodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-116364C
-
3'-Azido-3'-deoxythymidine-5'-triphosphate sodium
|
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Azide
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AZT triphosphate sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
|
Cat. No. |
Product Name |
|
Classification |
-
- HY-W013715A
-
dTTP trisodium
|
|
Nucleotides and their Analogs
|
Deoxythymidine-5'-triphosphate (dTTP) trisodium is one of the four nucleoside triphosphates used in the synthesis of DNA .
|
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- HY-W011142
-
|
|
Nucleotides and their Analogs
|
2'-Deoxyuridine 5'-monophosphate disodium is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .
|
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- HY-W040329
-
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- HY-154348
-
|
|
Nucleosides and their Analogs
|
4’,5’-Didehydro-5’-deoxy thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-138615
-
dTTP
|
|
Nucleotides and their Analogs
|
Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA .
|
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- HY-138615A
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dTTP sodium hydrate
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Nucleotides and their Analogs
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Deoxythymidine-5'-triphosphate (dTTP) sodium hydrate is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate trisodium salt is used in the synthesis of DNA .
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- HY-149160
-
|
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Nucleosides and their Analogs
|
5′-Amino-5′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154087
-
|
|
Nucleosides and their Analogs
|
3′-Bromo-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154740
-
|
|
Nucleosides and their Analogs
|
3′-Chloro-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-154697
-
|
|
Nucleosides and their Analogs
|
3-epi-Azido-3-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
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