5-ALA

By Targets:	ADC Linker (1) Apoptosis (6) Autophagy (6) Endogenous Metabolite (13) Isotope-Labeled Compounds (4) Mitophagy (6) Neuropeptide Y Receptor (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (2) Metabolic Disease (6) Neurological Disease (1)
Click Chemistry:	ADC Synthesis (1) Azide (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-133100

5-ALA benzyl ester hydrochloride Benzyl-ALA hydrochloride	Endogenous Metabolite	Cancer
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .

HY-N0305

5-Aminolevulinic acid hydrochloride 10+ Cited Publications 5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride	Autophagy Mitophagy Endogenous Metabolite Apoptosis	Metabolic Disease Cancer
5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-N0305S3

5-Aminolevulinic acid-13C-1 hydrochloride 5-ALA-¹³C-1 hydrochloride; δ-Aminolevulinic acid-¹³C-1 hydrochloride; 5-Amino-4-oxopentanoic acid-¹³C-1 hydrochloride	Apoptosis Autophagy Mitophagy Endogenous Metabolite	Metabolic Disease
5-Aminolevulinic acid- ¹³C-1 (5-ALA- ¹³C-1) hydrochloride is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-N0305S1

5-Aminolevulinic acid-d2 hydrochloride 5-ALA-d₂ hydrochloride; δ-Aminolevulinic acid-d₂ hydrochloride; 5-Amino-4-oxopentanoic acid-d₂ hydrochloride	Isotope-Labeled Compounds Autophagy Mitophagy Endogenous Metabolite Apoptosis	Metabolic Disease Cancer
5-Aminolevulinic acid-d₂ (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).

HY-W000450

5-Aminolevulinic acid 5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid	Endogenous Metabolite	Cardiovascular Disease Cancer
5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-N0305S

5-Aminolevulinic acid-15N hydrochloride 5-ALA-¹⁵N hydrochloride; δ-Aminolevulinic acid-¹⁵N hydrochloride; 5-Amino-4-oxopentanoic acid-¹⁵N hydrochloride	Isotope-Labeled Compounds Autophagy Mitophagy Endogenous Metabolite Apoptosis	Metabolic Disease Cancer
5-Aminolevulinic acid- ¹⁵N (hydrochloride) is the ¹⁵N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-W000450S

5-Aminolevulinic acid-13C 5-ALA-¹³C; δ-Aminolevulinic acid-¹³C; 5-Amino-4-oxopentanoic acid-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
5-Aminolevulinic acid- ¹³C is the ¹³C-labeled 5-Aminolevulinic acid. 5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-N0305S2

5-Aminolevulinic acid-13C hydrochloride 5-ALA-¹³C hydrochloride; δ-Aminolevulinic acid-¹³C hydrochloride; 5-Amino-4-oxopentanoic acid-¹³C hydrochloride	Apoptosis Autophagy Mitophagy Endogenous Metabolite	Metabolic Disease
5-Aminolevulinic acid- ¹³C (hydrochloride) is the ¹³C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].

HY-W749251

5-Aminolevulinic acid-13C2,15N hydrochloride 5-ALA-¹³C₂,¹⁵N hydrochloride; δ-Aminolevulinic acid-¹³C₂,¹⁵N hydrochloride; 5-Amino-4-oxopentanoic acid-¹³C₂,¹⁵N hydrochloride	Endogenous Metabolite Isotope-Labeled Compounds	Others
5-Aminolevulinic acid- ¹³C₂, ¹⁵N (5-ALA- ¹³C₂, ¹⁵N; δ-Aminolevulinic acid- ¹³C₂, ¹⁵N) is ¹³C- and ¹⁵N-labeled 5-Aminolevulinic acid (HY-W000450) .

HY-N0305R

5-Aminolevulinic acid (hydrochloride) (Standard) 5-ALA (hydrochloride) (Standard); δ-Aminolevulinic acid (hydrochloride) (Standard); 5-Amino-4-oxopentanoic acid (hydrochloride) (Standard)	Autophagy Endogenous Metabolite Apoptosis Mitophagy	Metabolic Disease Cancer
5-Aminolevulinic acid (hydrochloride) (Standard) is the analytical standard of 5-Aminolevulinic acid (hydrochloride). This product is intended for research and analytical applications. 0

HY-141150

Azido-PEG5-Ala-Ala-Asn-PAB	ADC Linker	Cancer
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-B1247

Protoporphyrin IX Maximum Cited Publications 15 Publications Verification	Endogenous Metabolite	Others
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma ^[5].

HY-B1247A

Protoporphyrin IX disodium	Endogenous Metabolite	Cancer
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma ^[5].

HY-B1247R

Protoporphyrin IX (Standard)	Endogenous Metabolite	Others
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma ^[5].

HY-P5896

Ala5-Galanin (2-11)	Neuropeptide Y Receptor	Neurological Disease
Ala5-Galanin (2-11) is a galanin receptor 2 (GAL₂R) specific agonist with a K_i of 258 nM .

Cat. No.	Product Name	Target	Research Area

HY-P5896

Ala5-Galanin (2-11)	Neuropeptide Y Receptor	Neurological Disease
Ala5-Galanin (2-11) is a galanin receptor 2 (GAL₂R) specific agonist with a K_i of 258 nM .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-133100

5-ALA benzyl ester hydrochloride Benzyl-ALA hydrochloride	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .

HY-N0305

5-Aminolevulinic acid hydrochloride 10+ Cited Publications 5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer	Autophagy Mitophagy Endogenous Metabolite Apoptosis
5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-B1247

Protoporphyrin IX Maximum Cited Publications 15 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma ^[5].

HY-W000450

5-Aminolevulinic acid 5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Amino acids Endogenous metabolite Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Disease Research Fields Cancer	Endogenous Metabolite
5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-N0305R

5-Aminolevulinic acid (hydrochloride) (Standard) 5-ALA (hydrochloride) (Standard); δ-Aminolevulinic acid (hydrochloride) (Standard); 5-Amino-4-oxopentanoic acid (hydrochloride) (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Autophagy Endogenous Metabolite Apoptosis Mitophagy
5-Aminolevulinic acid (hydrochloride) (Standard) is the analytical standard of 5-Aminolevulinic acid (hydrochloride). This product is intended for research and analytical applications. 0

HY-B1247R

Protoporphyrin IX (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma ^[5].

Cat. No.	Product Name	Chemical Structure

HY-N0305S3

5-Aminolevulinic acid-13C-1 hydrochloride
5-Aminolevulinic acid- ¹³C-1 (5-ALA- ¹³C-1) hydrochloride is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-N0305S1

5-Aminolevulinic acid-d2 hydrochloride
5-Aminolevulinic acid-d₂ (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).

HY-N0305S

5-Aminolevulinic acid-15N hydrochloride
5-Aminolevulinic acid- ¹⁵N (hydrochloride) is the ¹⁵N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-W000450S

5-Aminolevulinic acid-13C
5-Aminolevulinic acid- ¹³C is the ¹³C-labeled 5-Aminolevulinic acid. 5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-N0305S2

5-Aminolevulinic acid-13C hydrochloride
5-Aminolevulinic acid- ¹³C (hydrochloride) is the ¹³C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].

HY-W749251

5-Aminolevulinic acid-13C2,15N hydrochloride
5-Aminolevulinic acid- ¹³C₂, ¹⁵N (5-ALA- ¹³C₂, ¹⁵N; δ-Aminolevulinic acid- ¹³C₂, ¹⁵N) is ¹³C- and ¹⁵N-labeled 5-Aminolevulinic acid (HY-W000450) .

Cat. No.	Product Name		Classification

HY-141150

Azido-PEG5-Ala-Ala-Asn-PAB		Azide ADC Synthesis
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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5-ALA

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