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Animal tissues

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31

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7

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Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-113130
    Eicosadienoic acid
    1 Publications Verification

    		 Endogenous Metabolite Metabolic Disease
    Eicosadienoic acid is a rare, naturally occurring n-6 polyunsaturated fatty acid found mainly in animal tissues .
    Eicosadienoic acid
  • HY-N7032
    Uridine 5′-diphosphoglucose disodium salt
    5 Publications Verification

    UDP-D-Glucose disodium salt

    		 Endogenous Metabolite P2Y Receptor Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Uridine 5’-diphosphoglucose (UDP-glucose) disodium salt, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium salt is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium salt is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .
    Uridine 5′-diphosphoglucose disodium salt
  • HY-D0217
    Sulfobromophthalein disodium salt
    4 Publications Verification

    Bromosulfophthalein disodium salt

    		 Fluorescent Dye Metabolic Disease
    Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of agents and metabolites .
    Sulfobromophthalein disodium salt
  • HY-119433
    Asoprisnil

    J867

    		 Progesterone Receptor Endocrinology
    Asoprisnil (J867), a selective progesterone receptor modulator, exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human .
    Asoprisnil
  • HY-Y0469
    1-Aminohydantoin hydrochloride

    		Drug Metabolite Others
    1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection .
    1-Aminohydantoin hydrochloride
  • HY-115768A
    Compound 48/80 (trimer)

    Poly-p-methoxyphenethylmethylamine (trimer)

    		 Phospholipase Others
    Compound 48/80 (trimer) is a trimer of Compound 48/80 (HY-115768). Compound 48/80 is widely used in animal and tissue models as a "selective" mast cell activator .
    Compound 48/80 (trimer)
  • HY-138118
    Propyl nicotinate

    Nicotinic acid propyl ester

    		 Endogenous Metabolite Others
    Propyl nicotinate (Nicotinic acid propyl ester), the propyl ester of niacin, occurs in various animal and plant tissues, where it contributes to the formation of the coenzymes NAD and NADP.
    Propyl nicotinate
  • HY-149765
    Bone-1064

    		Fluorescent Dye Others
    Bone-1064 is a EuK-based PSMA tetramer bone probe for high-contrast visualization of bone in surrounding tissue. Bone-1064 specifically binds hydroxyapatite in bone tissue and can be used for NIR-II fluorescence imaging in animal models .
    Bone-1064
  • HY-134092
    N-Methyl Leukotriene C4

    N-Methyl-LTC4

    		 Leukotriene Receptor Inflammation/Immunology
    N-Methyl Leukotriene C4 stimulates contraction of airway smooth muscle in animals, with efficacy varying by tissue and species. For example, it can stimulate the lungs of bullfrogs to contract .
    N-Methyl Leukotriene C4
  • HY-N15029
    Destomycin A

    		Antibiotic Bacterial Fungal Parasite Adenylate Cyclase Infection
    Destomycin A is an aminoglycoside antibiotic with antibacterial (Gram-positive bacteria, Gram-negative bacteria), antifungal and anthelmintic activities. Destomycin A inhibits the polypeptide synthesis in cells of Escherichia coli and stimulation of adenylate cyclase in animal tissues .
    Destomycin A
  • HY-113044
    Uridine diphosphate glucose

    		Endogenous Metabolite P2Y Receptor Metabolic Disease
    Uridine diphosphate glucose is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine diphosphate glucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR 1.
    Uridine diphosphate glucose
  • HY-Y0469R
    1-Aminohydantoin (hydrochloride) (Standard)

    		Drug Metabolite Others
    1-Aminohydantoin (hydrochloride) (Standard) is the analytical standard of 1-Aminohydantoin (hydrochloride). This product is intended for research and analytical applications. 1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection .
    1-Aminohydantoin (hydrochloride) (Standard)
  • HY-136886
    IR-820
    1 Publications Verification

    New Indocyanine Green

    		 Fluorescent Dye Cancer
    IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
    IR-820
  • HY-129047B
    Recombinant Trypsin Solution

    		Biochemical Assay Reagents Others
    Recombinant Trypsin Solution is an animal-free trypsin solution used to digest cells or tissues. Recombinant Trypsin Solution has high stability at room temperature and gentle digestion, and can be used to digest weakly adherent cells or stem cells under low serum or serum-free culture conditions. Compared with traditional trypsin digestion solution, Recombinant Trypsin Solution does not contain any animal-derived ingredients, is gentle and effective, and can replace the application of animal-derived trypsin in cell digestion .
    Recombinant Trypsin Solution
  • HY-111646
    N6-Etheno 2'-deoxyadenosine

    		Nucleoside Antimetabolite/Analog Endogenous Metabolite Inflammation/Immunology
    N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues .
    N6-Etheno 2'-deoxyadenosine
  • HY-P2975
    Laminin β2 (Engelbreth-Holm-Swarm murine sarcoma basement membrane)

    Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)

    		 Endogenous Metabolite Biochemical Assay Reagents Neurological Disease
    Laminin β2 (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.
    Laminin β2 (Engelbreth-Holm-Swarm murine sarcoma basement membrane)
  • HY-115768
    Compound 48/80

    Poly-p-methoxyphenethylmethylamine

    		 Phospholipase Neurological Disease Cancer
    Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways .
    Compound 48/80
  • HY-N5034R
    Phosphorylethanolamine (Standard)

    Monoaminoethyl phosphate (Standard); NSC 254167 (Standard); O-Phosphoethanolamine (Standard)

    		 Endogenous Metabolite Metabolic Disease Cancer
    Phosphorylethanolamine (Standard) is the analytical standard of Phosphorylethanolamine. This product is intended for research and analytical applications. Phosphorylethanolamine (Monoaminoethyl phosphate) is present in most animal tissues and is also present in various human extracranial tumors. Phosphorylethanolamine is considered as the intermediate product of phospholipid metabolism. Phosphorylethanolamine is essential for the formation and maintenance of the cell membrane .
    Phosphorylethanolamine (Standard)
  • HY-131306B
    2-Hexadecenoic acid

    Gaidic acid

    		 Biochemical Assay Reagents Others
    2-Hexadecenoic acid is a natural unsaturated fatty acid. It is ubiquitously present in various animal and plant tissues, especially adipose tissue and certain vegetable oils, such as macadamia nut oil. 2-Hexadecenoic acid has unique chemical properties that make it an important component of cell membranes and storage lipids, and participates in various metabolic processes such as lipid metabolism and inflammation. It's also been linked to potential health benefits, including improved insulin sensitivity and a lower risk of heart disease.
    2-Hexadecenoic acid
  • HY-113044R
    Uridine diphosphate glucose (Standard)

    		P2Y Receptor Endogenous Metabolite Metabolic Disease
    Uridine diphosphate glucose (Standard) is the analytical standard of Uridine diphosphate glucose. This product is intended for research and analytical applications. Uridine diphosphate glucose is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine diphosphate glucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR .
    Uridine diphosphate glucose (Standard)
  • HY-105318
    LGD-2226

    		Androgen Receptor Metabolic Disease Endocrinology
    LGD-2226 is a selective and orally active androgen receptor modulator with an EC50 of 0.2 nM and a Ki of 1.5 nM for human androgen receptor. LGD-2226 shows tissue selectivity in animal models, with reduced effects on prostate compared to muscle. LGD-2226 can be used for muscle wasting, osteoporosis and sexual dysfunction .
    LGD-2226
  • HY-159067
    DEAE-dextran, MW 500000 hydrochloride

    DEAE-dextran, MW 500000 (hydrochloride), from bacterial (Leuconostoc mesenteroides); Diethylaminoethyl-dextran, MW 500000 hydrochloride

    		 Biochemical Assay Reagents Cancer
    DEAE-dextran, MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides)) is a high-molecular-weight positively charged polymer that significantly enhances the uptake of viral RNA by tissue culture cells. When employed in the delivery system for "tumor immunity" RNA-splenocyte transfer, DEAE-dextran can markedly extend the lifespan of tumor-bearing animals, comparable to that of actively immunized animals. Furthermore, DEAE-dextran serves as a complexing agent for nucleic acids, forming composite particles with DNA/RNA for extensive applications in gene delivery. Additionally, DEAE-dextran can be utilized as a coating for liposomes .
    DEAE-dextran, MW 500000 hydrochloride
  • HY-134658
    Hentriacontanoic acid

    		Biochemical Assay Reagents Others
    Hentriacontanoic acid is a long-chain saturated fatty acid commonly found in various plant and animal tissues, especially in certain waxes and oils, such as beeswax and lanolin. Hentriacontanoic acid has unique chemical properties that make it an important ingredient in many industrial products, including cosmetics, candles and lubricants. It also has potential physiological roles in regulating lipid metabolism and protecting against oxidative stress, although its biological function is not fully understood.
    Hentriacontanoic acid
  • HY-W021265
    Cyclohexane-1,2,3,4,5,6-hexaol

    Cyclohexane-1,2,3,4,5,6-hexol

    		 Biochemical Assay Reagents Others
    Cyclohexane-1,2,3,4,5,6-hexaol, also known as inositol or inositol, is a cyclic sugar alcohol consisting of a six-carbon ring with six hydroxyl groups. This compound is important for its biological activity and is widely distributed in nature, especially in plant and animal tissues. It plays a role in various physiological processes such as signal transduction, osmoregulation and lipid metabolism. In addition, Cyclohexane-1,2,3,4,5,6-hexaol has potential investigational effects, including improving conditions related to insulin resistance, polycystic ovary syndrome, and mental health conditions. It can also be used as a supplement in animal feed and human nutritional products.
    Cyclohexane-1,2,3,4,5,6-hexaol
  • HY-121965
    β-D-Glucose

    		Biochemical Assay Reagents Endogenous Metabolite Others
    β-D-Glucose, also known as glucose, is a monosaccharide, the most important carbohydrate in biological systems, the main energy source of cells, and plays a key role in various metabolic processes. β-D-Glucose has unique chemical properties that make it an abundant component in plant and animal tissues and is readily metabolized by organisms to produce cellular energy. It is commonly used to improve hypoglycemia and dehydration, and as a sweetener and preservative in food and beverage production.
    β-D-Glucose
  • HY-N7032S1
    Uridine 5′-diphosphoglucose-13C6 disodium

    UDP-D-Glucose-13C6 disodium

    		 P2Y Receptor Endogenous Metabolite Neurological Disease
    Uridine 5′-diphosphoglucose- 13C6 (disodium) is the 13C labeled Uridine 5′-diphosphoglucose disodium salt[1]. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[2].
    Uridine 5′-diphosphoglucose-13C6 disodium
  • HY-B1113
    Diazinon

    Dimpylate

    		 Parasite Infection
    Diazinon is an orally active, irreversible AChE inhibitor and insecticide that can be absorbed through the digestive system, skin or respiratory tract. Diazinon inhibits AChE, leading to accumulation of acetylcholine, which in turn overstimulates ACh receptors and affects the nervous system. Diazinon also produces reactive oxygen species (ROS)， which induce oxidative stress in various tissues. Diazinon is mainly used in the agricultural field as an insecticide and may have potential effects on human and animal health .
    Diazinon
  • HY-N5034
    Phosphorylethanolamine
    3 Publications Verification

    Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine

    		 Endogenous Metabolite Neurological Disease Metabolic Disease Cancer
    Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases .
    Phosphorylethanolamine
  • HY-131146
    AMOZ

    3-Amino-5-morpholinomethyl-2-oxazolidone

    		 Antibiotic Infection
    AMOZ is a carcinogenic metabolite of Furaltadone (HY-B1148A), which forms stable tissue residues by covalently binding to proteins as a hapten. AMOZ can be coupled with carrier proteins (such as BSA/OVA) to induce immune response and is released after acid hydrolysis. AMOZ residues can be detected by competitive ELISA method, and the detection limit in the monoclonal antibody 2E5.1 test is as low as 0.16 μg/kg (shrimp sample). AMOZ can be used as a typical marker to monitor drug residues in animal-derived foods in the field of food safety[1][2].
    AMOZ
  • HY-B1610J
    Sodium Citrate Buffer, 0.5M, pH 5.0

    		Biochemical Assay Reagents Others
    Sodium citrate buffer, 0.5M, pH 5.0, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer, 0.5M, pH 5.0 is used in heat induced epitope retrieval (HIER) methods to reverse the loss of antigenicity that occurs with some epitopes in formalin-fixed paraffin embedded tissues. Sodium citrate buffer, 0.5M, pH 5.0 is the preferred solution for most antibodies . Sodium citrate buffer, 0.5M, pH 5.0 is used as solution for captisol in animal tumor models .
    Sodium Citrate Buffer, 0.5M, pH 5.0
  • HY-122010
    NVP-AAD777

    		VEGFR Others
    NVP-AAD777 is a specific inhibitor of VEGFR-2, demonstrated in vivo by its effective suppression of phospho-VEGFR-2 (Tyr1175) signaling in rat lung tissues. Unlike the nonspecific VEGFR inhibitor SUG-5416, NVP-AAD777 did not induce emphysematous changes in the lungs after three weeks of treatment, even when combined with exposure to cigarette smoke. Additionally, there were no alterations observed in vascular density compared to control animals. This indicates NVP-AAD777's targeted action in inhibiting VEGFR-2 without adverse pulmonary effects, highlighting its potential therapeutic utility in managing conditions associated with aberrant VEGFR-2 signaling .
    NVP-AAD777

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