Search Result
Results for "
Anti-inflammatory agent 1
" in MedChemExpress (MCE) Product Catalog:
2
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-148456
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- HY-128695
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- HY-U00273
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- HY-162137
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Apoptosis
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Inflammation/Immunology
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Hepatoprotective agent-1 (compound 1b) is a hepatoprotective agenrt. Hepatoprotective agent-1 shows anti-inflammatory, antiapoptotic and antifibrotic effects .
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- HY-W050088S
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- HY-111392
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- HY-156973
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- HY-132127
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- HY-106473
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- HY-N2988A
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- HY-124448
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- HY-17486
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- HY-150002
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- HY-N7700A
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- HY-N6804
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- HY-N8149
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- HY-N8038
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(Rac)-Deoxypodophyllotoxin
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Others
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Others
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Isoanthricin ((Rac)-Deoxypodophyllotoxin) is the racemate of Deoxypodophyllotoxin. Deoxypodophyllotoxin is a potent antitumor and anti-inflammatory agent .
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- HY-W173220
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- HY-U00063
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- HY-B1597
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Benzyldimethylhexadecylammonium chloride
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Bacterial
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Infection
Inflammation/Immunology
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Cetalkonium chloride is an ammonium antiseptic agent used in many topical agents for infections of mouth, throat and eye. Cetalkonium chloride acts as anti-inflammatory amphiphilic agent .
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- HY-N2012
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Others
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Inflammation/Immunology
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7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent .
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- HY-133159
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(-)-Resolvin E2
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Others
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Inflammation/Immunology
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Resolvin E2 ((-)-Resolvin E2), a proresolving lipid mediator, is useful as a lead for anti-inflammatory agent .
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- HY-113442
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- HY-17491
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RU 43-715; Sandoz-43-715
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Others
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Inflammation/Immunology
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Proquazone (RU 43-715) is a chemically distinctive non-steroidal anti-inflammatory agent (NSAID). unlike most other NSAIDs, Proquazone does not have a free acid group in its structure. Proquazone may inhibit or arrest progression of bone erosions. Proquazone is an orally active anti-inflammatory, analgesic and anti-pyretic agent .
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- HY-123219
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Bacterial
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Infection
Inflammation/Immunology
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Salifluor is a broad spectrum antimicrobial agent that has been investigated for its abilities to inhibit dental plaque formation. Salifluor can act as an effective anti-inflammatory agent .
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- HY-N8875
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Others
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Inflammation/Immunology
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Scillascilloside B-1 can be isolated from Scilla scilloides. Scilla scilloides promotes blood circulation, and is an analgesic and anti-inflammatory agent .
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- HY-N3007
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Others
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Inflammation/Immunology
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Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) by chalcone isomerase. Naringenin chalcone is an orally active anti-inflammatory and antiallergic agent .
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- HY-105852
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Propoxaline
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Others
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Neurological Disease
Inflammation/Immunology
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Proxazole (Propoxaline) is an anti-inflammatory agent. Proxazole prevents Indomethacin (HY-14397)-induced ulcers without anti-secretory effect. Proxazole is also a spasmolytic papaverine-like agent .
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- HY-B1597R
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Bacterial
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Infection
Inflammation/Immunology
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Cetalkonium (chloride) (Standard) is the analytical standard of Cetalkonium (chloride). This product is intended for research and analytical applications. Cetalkonium chloride is an ammonium antiseptic agent used in many topical agents for infections of mouth, throat and eye. Cetalkonium chloride acts as anti-inflammatory amphiphilic agent .
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- HY-148181
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c-Fms
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Inflammation/Immunology
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c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor with an IC50 value of 17 nM. c-Fms-IN-13 can be used as an anti-inflammatory agent .
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- HY-B2114
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Escin
2 Publications Verification
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Apoptosis
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Metabolic Disease
Inflammation/Immunology
Cancer
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Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent .
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- HY-N6644
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Others
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Inflammation/Immunology
Cancer
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Crocin III is a crocetin from saffron (Crocus sutivus L.). Crocetins inhibit cell growth of tumor cells and has anti-inflammatory activity. Crocins serve as spices and coloring agents .
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- HY-W040265
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N-Phenylanthranilic acid
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Chloride Channel
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Inflammation/Immunology
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Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent - .
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- HY-130289
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4-Hydroxy docosahexaenoic acid; (±)4-HDoHE
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PPAR
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Metabolic Disease
Inflammation/Immunology
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(±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent .
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- HY-103222
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3',4'-Dimethoxy-αNF
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Aryl Hydrocarbon Receptor
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Inflammation/Immunology
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DiMNF (3',4'-Dimethoxy-αNF) is a selective aryl hydrocarbon receptor (AHR) modulator. DiMNF is a competitive AHR ligand (IC50 = 21 nM) with apparent antagonistic activity. DiMNF can be used as an anti-inflammatory agent .
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- HY-19589
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- HY-N0295
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Catechaldehyde; Protocatechuic aldehyde; Rancinamycin IV
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Reactive Oxygen Species
Bacterial
Endogenous Metabolite
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Infection
Cancer
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Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent .
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- HY-107796
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COX
Apoptosis
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Inflammation/Immunology
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Metamizol magnesium is an orally active cyclooxygenase (COX) inhibitor. Metamizole magnesium can inhibit cell proliferation and promote cell apoptosis. Metamizole magnesium has anti-inflammatory and antioxidant activities. Metamizole magnesium is an antipyretic, analgesic and spasmolytic agent .
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- HY-A0259
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COX
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Inflammation/Immunology
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Floctafenine, a nonsteroidal anti-inflammatory agent (NSAID), acts as an effective analgesic agent . Floctafenine is an inhibitor of COX-1 and COX-2 activities in vitro,showing a slightly higher potency towards COX-I. Floctafenine is used for the research of short term pain research .
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- HY-P2275B
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- HY-W012634
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Bacterial
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Infection
Metabolic Disease
Inflammation/Immunology
Cancer
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Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent [1][2][3][4].
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- HY-N0192S
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β-Arbutin-d4
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Isotope-Labeled Compounds
Tyrosinase
Endogenous Metabolite
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Cancer
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Arbutin-d4 is deuterium labeled Arbutin. Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase in melanocytes, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents[1]. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties[2][3].
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- HY-N6644R
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Others
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Inflammation/Immunology
Cancer
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Crocin III (Standard) is the analytical standard of Crocin III. This product is intended for research and analytical applications. Crocin III is a crocetin from saffron (Crocus sutivus L.). Crocetins inhibit cell growth of tumor cells and has anti-inflammatory activity. Crocins serve as spices and coloring agents .
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- HY-146483
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Amyloid-β
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Neurological Disease
Inflammation/Immunology
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Anti-Aβ agent 1A (compound M15) has potent activity against amyloid-β. Anti-Aβ agent 1A possesses can significantly inhibit LPS-induced levels of IL-1β, IL-6 and TNF-α, and reduces the apoptosis of SH-SY5Y induced by H2O2 through mitochondria pathway. Anti-Aβ agent 1A possesses antioxidant, anti-inflammatory, anti-Aβ toxicity and neuroprotective activities. Anti-Aβ agent 1A can be used for researching Alzheimer’s disease (AD) .
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- HY-N7133
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N-Phenylaniline hydrochloride
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Fungal
Bacterial
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Metabolic Disease
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Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and a common structure in non-steroidal anti-inflammatory drugs (NSAIDs) that uncouples oxidative phosphorylation in mitochondria, leading to a decrease in hepatic cell ATP levels and causing liver cell damage. Diphenylamine hydrochloride is also an industrial antioxidant, a dyeing mordant, and is used in agriculture as an antifungal and antibacterial agent .
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- HY-N10429
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(+)-Geissoschizoline
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Cholinesterase (ChE)
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Neurological Disease
Inflammation/Immunology
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Geissoschizoline ((+)-Geissoschizoline) is a potent inhibitor of human AChE/BChE, with IC50s of 20.40 µM and 10.21 µM, respectively. Geissoschizoline emerges as a possible multi-target prototype that can be very useful in studies of preventing neurodegeneration and restoring neurotransmission. Geissoschizoline aiso is a potent anti-inflammatory agent .
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- HY-105172
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CAP-232; TLN-232
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Somatostatin Receptor
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Inflammation/Immunology
Cancer
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TT-232 (CAP-232), a somatostatin derivative, is a peptide SSTR1/SSTR4 agonist. TT-232 inhibits cancer cell proliferation and induces apoptosis. TT-232 is also a broad-spectrum anti-inflammatory and analgesic agent .
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- HY-N0295R
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Reactive Oxygen Species
Bacterial
Endogenous Metabolite
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Infection
Cancer
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Protocatechualdehyde (Standard) is the analytical standard of Protocatechualdehyde. This product is intended for research and analytical applications. Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent .
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- HY-N0192
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Arbutin
1 Publications Verification
β-Arbutin
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Tyrosinase
Endogenous Metabolite
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Cancer
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Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase, with Ki app values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents . Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties .
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- HY-P3223
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Opioid Receptor
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Neurological Disease
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Biphalin TFA, a BBB-penetrable opioid peptide analog, contains two active enkephalin pharmacophores. Biphalin TFA has high affinity for opioid receptors. Biphalin TFA shows analgesic effect in acute, neuropathic, and chronic animal pain models. Biphalin TFA is also an antiviral, antiproliferative, anti-inflammatory, and neuroprotective agent .
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- HY-116005
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Adenosine Kinase
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Neurological Disease
Inflammation/Immunology
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A-286501 is an orally active and potent carbocyclic nucleoside adenosine kinase inhibitor with an IC50 value of 0.47 nM, which shows analgesic and anti-inflammatory effects. A-286501 reduces nociception in animal models of acute (thermal), inflammatory (formalin and carrageenan) and neuropathic (L5/L6 nerve ligation and streptozotocin-induced diabetic) pain. A-286501 also reduces Carrageenan (HY-125474)-induced paw edema and myeloperoxidase activity in the injured paw. A-286501 is promising for research of analgesic and anti-inflammatory agents .
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- HY-W012634R
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Bacterial
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Infection
Metabolic Disease
Inflammation/Immunology
Cancer
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Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .
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- HY-19017
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- HY-121681
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- HY-19017B
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- HY-163332
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Glucosidase
Dipeptidyl Peptidase
Glutathione Peroxidase
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Cardiovascular Disease
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MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC50s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent .
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- HY-N0192R
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Tyrosinase
Endogenous Metabolite
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Cancer
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Arbutin (Standard) is the analytical standard of Arbutin. This product is intended for research and analytical applications. Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents . Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties .
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- HY-124099
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Others
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Inflammation/Immunology
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SCH 40120 is a potent leukotriene inhibitor with antiinflammatory effects. SCH 40120 suppresses T cell proliferative responses, antigen-specific and poly-clonally-induced in vitro antibody responses. SCH 40120 suppresses an edematous response and inhibits the recruitment of circulating neutrophils into sites of inflammation. SCH 40120 is proming for rasearch of anti-psoriatic agents .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P2275B
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- HY-105172
-
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CAP-232; TLN-232
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Somatostatin Receptor
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Inflammation/Immunology
Cancer
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TT-232 (CAP-232), a somatostatin derivative, is a peptide SSTR1/SSTR4 agonist. TT-232 inhibits cancer cell proliferation and induces apoptosis. TT-232 is also a broad-spectrum anti-inflammatory and analgesic agent .
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- HY-P3223
-
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Opioid Receptor
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Neurological Disease
|
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Biphalin TFA, a BBB-penetrable opioid peptide analog, contains two active enkephalin pharmacophores. Biphalin TFA has high affinity for opioid receptors. Biphalin TFA shows analgesic effect in acute, neuropathic, and chronic animal pain models. Biphalin TFA is also an antiviral, antiproliferative, anti-inflammatory, and neuroprotective agent .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N7700A
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-
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- HY-N6804
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-
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- HY-N2012
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-
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- HY-N3007
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-
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- HY-B2114
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-
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- HY-N2988A
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-
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- HY-N8149
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-
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- HY-N8038
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-
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- HY-113442
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-
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- HY-N8875
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-
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- HY-N6644
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-
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- HY-N0295
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-
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- HY-W012634
-
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Microorganisms
Source classification
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Bacterial
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Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent [1][2][3][4].
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- HY-N6644R
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-
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- HY-N7133
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-
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- HY-N10429
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-
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- HY-N0295R
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-
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- HY-N0192
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-
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- HY-W012634R
-
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Microorganisms
Source classification
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Bacterial
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Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .
|
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- HY-N0192R
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-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W050088S
-
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Isoxepac-d6 is the deuterium labeled Isoxepac (HY-W050088). Isoxepac is a nonsteroidal anti-inflammatory agent[1].
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- HY-N0192S
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Arbutin-d4 is deuterium labeled Arbutin. Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase in melanocytes, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents[1]. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties[2][3].
|
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