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Antineoplastic agent-1

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

5

Peptides

2

Inhibitory Antibodies

1

Natural
Products

1

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-152845
    Ficonalkib

    		Anaplastic lymphoma kinase (ALK) Cancer
    Ficonalkib is a potent inhibitor of Anaplastic lymphoma kinase (ALK), the tyrosine kinase receptor. Ficonalkib, can be used as an antineoplastic agent .
    Ficonalkib
  • HY-P990073
    Davutamig

    REGN-5093

    		 c-Met/HGFR Cancer
    Davutamig (REGN-5093) is a humanIgG4-kappa, anti-MET bispecific antibody targeting two different nonoverlapping epitopes on MET. Davutamig is an antineoplastic agent .
    Davutamig
  • HY-133887
    Methotrexate α-tert-butyl ester

    		Antifolate DNA/RNA Synthesis Cancer
    Methotrexate α-tert-butyl ester, capped by OtBu, significantly reduces tumor growth in HT1080 tumor bearing mice. Methotrexate is an antimetabolite and antifolate agent and is also an immunosuppressant and antineoplastic agent .
    Methotrexate α-tert-butyl ester
  • HY-121261
    Antineoplastic agent-1

    		Necroptosis Apoptosis Cancer
    Antineoplastic agent-1 is an alkylating agent and a genotoxic agent that can induce DNA damage. Antineoplastic agent-1 can lead to irreversible damage and progressive death of liver cells due to necroptosis and apoptosis. Antineoplastic agent-1 can cause alkylation damage to hematopoietic cells and stromal cells in the bone marrow. Antineoplastic agent-1 can be used in tumor research .
    Antineoplastic agent-1
  • HY-109140
    Tuvatexib

    		VDAC Cancer
    Tuvatexib is an antineoplastic agent .
    Tuvatexib
  • HY-167895
    Terfluranol

    		Others Cancer
    Terfluranol is a bibenzyl derivative. Terfluranol is an antineoplastic agent .
    Terfluranol
  • HY-116280
    Aceratioside

    		Others Cancer
    Aceratioside, a tetralin glucoside, is a weakly cytostatic constituent. Aceratioside is an antineoplastic agent .
    Aceratioside
  • HY-130564
    Didemnin C

    		Others Cancer
    Didemnin C is a cyclic depsipeptide that can be used as an anti-neoplastic agent .
    Didemnin C
  • HY-106120
    Adolezesin

    Adozelesin; U 73975

    		 Drug Isomer Cancer
    Adolezesin (U 73975) is an analog of CC-1065. Adolezesin is an antineoplastic agent .
    Adolezesin
  • HY-148803
    Vabametkib

    		c-Met/HGFR Cancer
    Vabametkib is a potent inhibitor of hepatocyte growth factor receptor (HGFR). Vabametkib inhibits Hs746T cells proliferation and inhibits c-Met with an IC50 value of 7 nM. Vabametkib can be used as an antineoplastic agent .
    Vabametkib
  • HY-113642
    CP-67804

    		Topoisomerase Cancer
    CP-67804 is a quinolone derivative, is a topoisomerase II-targeted agent. CP-67804 effectively enhances DNA cleavage mediated by eukaryotic topoisomerase II. CP-67804 has potential as an antineoplastic agent .
    CP-67804
  • HY-B0245
    Busulfan
    10+ Cited Publications

    		 DNA Alkylator/Crosslinker Apoptosis Inflammation/Immunology Cancer
    Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent .
    Busulfan
  • HY-P4149
    Imsamotide

    IDO194-214

    		 Indoleamine 2,3-Dioxygenase (IDO) Inflammation/Immunology Cancer
    Imsamotide (IDO194-214) is a Indoleamine 2,3-Dioxygenase (IDO) peptide with sequences of DTLLKALLEIASCLEKALQVF, the IDO194-214. Imsamotide is also an immunological agent for active immunization, as well as an antineoplastic agent .
    Imsamotide
  • HY-B0245S
    Busulfan-d8

    		DNA Alkylator/Crosslinker Apoptosis Inflammation/Immunology Cancer
    Busulfan-d8 is a deuterium labeled Busulfan. Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent[1][2][3].
    Busulfan-d8
  • HY-147275
    Tazide

    		Biochemical Assay Reagents Cancer
    Tazide is an antineoplastic agent . Tazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Tazide
  • HY-141431
    Cbl-b-IN-2

    		E3 Ligase Ligand-Linker Conjugates Inflammation/Immunology Cancer
    Cbl-b-IN-2 (Example 8) is an orally bioavailable compound, can inhibit the E3 enzyme Casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) in the ubiquitin proteasome pathway. Cbl-b-IN-2 can be used to modulate the immune system and diseases amenable to immune system modulation. Cbl-b-IN-2 (Example 8) also may be administered to an individual with cancer, either alone or as part of a combination, with one or more of an immune checkpoint inhibitor, an anti-neoplastic agent, and radiation agent .
    Cbl-b-IN-2