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Results for "

Avermectin

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15311
    Avermectin B1
    4 Publications Verification

    Abamectin; Avermectin B1a-Avermectin B1b mixt.

    		 Parasite Autophagy Apoptosis Reactive Oxygen Species Antibiotic Infection Inflammation/Immunology
    Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .
    Avermectin B1
  • HY-15308
    Avermectin B1a

    Abamectin B1a

    		 Parasite Antibiotic Infection
    Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
    Avermectin B1a
  • HY-147001
    5-O-Demethyl-28-hydroxy-Avermectin A1a

    		Others Others
    5-O-Demethyl-28-hydroxy-Avermectin A1a is a degradation product of Avermectin B1a (HY-15308).
    5-O-Demethyl-28-hydroxy-Avermectin A1a
  • HY-126937
    Ivermectin B1a
    1 Publications Verification

    		 Parasite SARS-CoV Infection
    Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) . Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
    Ivermectin B1a
  • HY-B0837
    Emamectin Benzoate

    MK-244

    		 Parasite GABA Receptor Reactive Oxygen Species Apoptosis Infection Neurological Disease
    Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .
    Emamectin Benzoate
  • HY-12643
    Eprinomectin

    MK-397

    		 Parasite Bacterial Infection
    Eprinomectin (MK-397) is an avermectin with anthelmintic, insecticidal and acaricidal activities.
    Eprinomectin
  • HY-15311R
    Avermectin B1 (Standard)

    		Parasite Autophagy Apoptosis Reactive Oxygen Species Antibiotic Infection Inflammation/Immunology
    Avermectin B1 (Standard) is the analytical standard of Avermectin B1. This product is intended for research and analytical applications. Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .
    Avermectin B1 (Standard)
  • HY-15308R
    Avermectin B1a (Standard)

    		Parasite Antibiotic Infection
    Avermectin B1a (Standard) is the analytical standard of Avermectin B1a. This product is intended for research and analytical applications. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
    Avermectin B1a (Standard)
  • HY-N8484
    Eprinomectin B1b

    		Parasite Infection
    Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.
    Eprinomectin B1b
  • HY-12643R
    Eprinomectin (Standard)

    MK-397 (Standard)

    		 Parasite Bacterial Infection
    Eprinomectin (Standard) is the analytical standard of Eprinomectin. This product is intended for research and analytical applications. Eprinomectin (MK-397) is an avermectin with anthelmintic, insecticidal and acaricidal activities.
    Eprinomectin (Standard)
  • HY-138149
    2-epi-Abamectin

    epi-Avermectin B1a

    		 Others Infection
    2-epi-Abamectin is a degradation product of Abamectin. It is toxic to the two-spotted spider mite in a contact assay with an LC50 value of 4 ppm, which is approximately 100-fold less potent than abamectin.
    2-epi-Abamectin
  • HY-12643S
    Eprinomectin-d3

    MK-397-d3

    		 Isotope-Labeled Compounds Infection
    Eprinomectin-d3 (MK-397-d3) is the deuterium-labeled Eprinomectin (HY-12643) . Eprinomectin is an avermectin for use as a topical endectocide for cattle .
    Eprinomectin-d3
  • HY-130349
    Emamectin B1a

    L-656,748

    		 Others Infection
    Emamectin B1a is a semisynthetic derivative of avermectin B1a. It binds to GABAA receptors (Ki=17.6 nM in rat brain membranes), including those containing β1, β2, or β3 subunits (IC50s=57, 210, and 49.8 nM for α1β1γ2, α1β2γ2, and α1β3γ2 subunits, respectively), and potentiates the GABA response.2 Emamectin B1a also binds to and inhibits glycine receptors (IC50=218 nM in rat spinal cord). Emamectin B1a induces mortality in 90% of S. exigua larvae in a diet incorporation assay at a dose of 1.067 ng/ml, which is approximately 1,500-fold more toxic than avermectin B1. It is effective against neonate S. eridania larvae in a foliage spray bioassay and when applied topically.
    Emamectin B1a

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