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B-cell maturation antigen

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibody-Drug Conjugates (ADCs) (1) CD3 (3)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Inflammation/Immunology (2)

4

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1

Peptides

4

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2

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6

Recombinant Proteins

Targets Recommended: HuR PSMA Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor FLT3 BCL6 CD74 Tim3 BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Belantamab mafodotin GSK2857916; Belantamab mafodotin-blm	Antibody-Drug Conjugates (ADCs)	Cancer
Belantamab mafodotin (GSK2857916) is composed of humanized and focused monoclonal antibody against B cell maturation antigen (BCMA) and McMMAF. Belantamab mafodotin has anti-myeloma activity .

Pacanalotamab AMG 420; BI-836909	CD3	Cancer
Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines .

Pavurutamab AMG-701	CD3	Inflammation/Immunology Cancer
Pavurutamab (AMG-701) is a bispecific T cell engager molecule that anti-CD3 and anti-B cell **maturation antigens (BCMA**). Pavurutamab has an extended half-life based on Pacanalotamab (HY-P99798). The Fc of Pavurutamab is coupled to molecules to improve pharmacokinetic parameters. Pavurutamab has potential applications in immune regulation and multiple myeloma (MM) .

ABBV-383 TNB 383B; Etentamig	CD3	Cardiovascular Disease Inflammation/Immunology Cancer
ABBV-383 (ABBV-383) is a BCMA × CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen (BCMA) and activate the T-cell surface glycoprotein CD3 complex. ABBV-383 can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases .

Cat. No.	Product Name	Target	Research Area

BCMA72-80	Peptides	Cancer
BCMA72-80 is a HLA-A2-specific B-cell maturation antigen (BCMA) peptide, with great affinity to HLA-A2, used in the research of multiple myeloma or other B-cell maturation antigen expressing tumors .

Cat. No.	Product Name	Target	Research Area

Belantamab mafodotin GSK2857916; Belantamab mafodotin-blm	Antibody-Drug Conjugates (ADCs)	Cancer
Belantamab mafodotin (GSK2857916) is composed of humanized and focused monoclonal antibody against B cell maturation antigen (BCMA) and McMMAF. Belantamab mafodotin has anti-myeloma activity .

Pacanalotamab AMG 420; BI-836909	CD3	Cancer
Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines .

Pavurutamab AMG-701	CD3	Inflammation/Immunology Cancer
Pavurutamab (AMG-701) is a bispecific T cell engager molecule that anti-CD3 and anti-B cell **maturation antigens (BCMA**). Pavurutamab has an extended half-life based on Pacanalotamab (HY-P99798). The Fc of Pavurutamab is coupled to molecules to improve pharmacokinetic parameters. Pavurutamab has potential applications in immune regulation and multiple myeloma (MM) .

ABBV-383 TNB 383B; Etentamig	CD3	Cardiovascular Disease Inflammation/Immunology Cancer
ABBV-383 (ABBV-383) is a BCMA × CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen (BCMA) and activate the T-cell surface glycoprotein CD3 complex. ABBV-383 can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases .

Cat. No.	Product Name	Category	Target	Chemical Structure

Pacanalotamab AMG 420; BI-836909	Classification of Application Fields Disease Research Fields Cancer	CD3
Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines .

Pavurutamab AMG-701	Classification of Application Fields Disease Research Fields Cancer	CD3
Pavurutamab (AMG-701) is a bispecific T cell engager molecule that anti-CD3 and anti-B cell **maturation antigens (BCMA**). Pavurutamab has an extended half-life based on Pacanalotamab (HY-P99798). The Fc of Pavurutamab is coupled to molecules to improve pharmacokinetic parameters. Pavurutamab has potential applications in immune regulation and multiple myeloma (MM) .

Recombinant Proteins Recommended:

B Cell Maturation Antigen (BCMA)

Species:	Human (1) Rhesus Macaque (2) Mouse (2) Rat (1)
Tag:	His (2) Avi (2) Fc (5)
Source:	HEK293 (6)

Cat. No.	Compare	Product Name	Species	Source

	BCMA/TNFRSF17 Protein, Human (HEK293, His) Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA	Human	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Human (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 54 amino acids (M1-A54) and is produced in HEK293 cells.

	BCMA/TNFRSF17 Protein, Mouse (HEK293, His-Fc) Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA	Mouse	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Mouse (HEK293, His-Fc) is a recombinant protein with a C-Terminal Fc label and a C-Terminal His label, It is produced in HEK293 cells.

	BCMA/TNFRSF17 Protein, Rat (HEK293, Fc) Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA	Rat	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Rat (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 49 amino acids (M1-T49) and is produced in HEK293 cells.

	BCMA/TNFRSF17 Protein, Rhesus Macaque (HEK293, Fc) Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA	Rhesus Macaque	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Rhesus Macaque (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 53 amino acids (M1-A53) and is produced in HEK293 cells.

	BCMA/TNFRSF17 Protein, Mouse (Biotinylated, HEK293, Fc-Avi) Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA	Mouse	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Mouse (Biotinylated, HEK293, Fc-Avi) is a biotinylated recombinant protein with a C-Terminal Avi label and a C-Terminal Fc label, It is produced in HEK293 cells.

	BCMA/TNFRSF17 Protein, Rhesus Macaque (Biotinylated, HEK293, Fc-Avi) Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA	Rhesus Macaque	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Rhesus Macaque (Biotinylated, HEK293, Fc-Avi) is a biotinylated recombinant protein with a C-Terminal Avi label and a C-Terminal Fc label, It consists of 53 amino acids (M1-A53) and is produced in HEK293 cells.

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