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Results for "

B1a

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Natural
Products

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147002
    7-O-Methyl Ivermectin B1a

    		Others Others
    7-O-Methyl Ivermectin B1a is an analogue of Ivermectin B1a (HY-126937).
    7-O-Methyl Ivermectin B1a
  • HY-126937
    Ivermectin B1a
    1 Publications Verification

    		 Parasite SARS-CoV Infection
    Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) [1]. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
    Ivermectin B1a
  • HY-15308
    Avermectin B1a

    Abamectin B1a

    		 Parasite Antibiotic Infection
    Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
    Avermectin B1a
  • HY-147001
    5-O-Demethyl-28-hydroxy-Avermectin A1a

    		Others Others
    5-O-Demethyl-28-hydroxy-Avermectin A1a is a degradation product of Avermectin B1a (HY-15308).
    5-O-Demethyl-28-hydroxy-Avermectin A1a
  • HY-B0837
    Emamectin Benzoate

    MK-244

    		 Parasite GABA Receptor Reactive Oxygen Species Apoptosis Infection Neurological Disease
    Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate [1] .
    Emamectin Benzoate
  • HY-15308R
    Avermectin B1a (Standard)

    		Parasite Antibiotic Infection
    Avermectin B1a (Standard) is the analytical standard of Avermectin B1a. This product is intended for research and analytical applications. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
    Avermectin B1a (Standard)
  • HY-123686
    Ivermectin B1a monosaccharide

    		Parasite Infection
    Ivermectin B1a monosaccharide is a modified Ivermectin B1a (HY-126937). Ivermectin B1a monosaccharide is an antiparasite agent with a minimum concentration for full activity in Haemonchus contortus larval development of 0.001 μg/mL [1].
    Ivermectin B1a monosaccharide
  • HY-130349
    Emamectin B1a

    L-656,748

    		 Others Infection
    Emamectin B1a is a semisynthetic derivative of avermectin B1a. It binds to GABAA receptors (Ki=17.6 nM in rat brain membranes), including those containing β1, β2, or β3 subunits (IC50s=57, 210, and 49.8 nM for α1β1γ2, α1β2γ2, and α1β3γ2 subunits, respectively), and potentiates the GABA response.2 Emamectin B1a also binds to and inhibits glycine receptors (IC50=218 nM in rat spinal cord). Emamectin B1a induces mortality in 90% of S. exigua larvae in a diet incorporation assay at a dose of 1.067 ng/ml, which is approximately 1,500-fold more toxic than avermectin B1. It is effective against neonate S. eridania larvae in a foliage spray bioassay and when applied topically.
    Emamectin B1a
  • HY-137252
    22,23-Dihydroavermectin B1a aglycon

    Ivermectin Impurity G

    		 Parasite Infection
    22,23-Dihydroavermectin B1a aglycon is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity.
    22,23-Dihydroavermectin B1a aglycon
  • HY-138149
    2-epi-Abamectin

    epi-Avermectin B1a

    		 Others Infection
    2-epi-Abamectin is a degradation product of Abamectin. It is toxic to the two-spotted spider mite in a contact assay with an LC50 value of 4 ppm, which is approximately 100-fold less potent than abamectin.
    2-epi-Abamectin
  • HY-15311
    Avermectin B1
    4 Publications Verification

    Abamectin; Avermectin B1a-Avermectin B1b mixt.

    		 Parasite Autophagy Apoptosis Reactive Oxygen Species Antibiotic Infection Inflammation/Immunology
    Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy [1] .
    Avermectin B1

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