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Results for "

CS1

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Fluorescent Dye

1

Peptides

1

Inhibitory Antibodies

10

Recombinant Proteins

3

Isotope-Labeled Compounds

3

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12515CS1

    (R)-YC-93-d3 free base

    Isotope-Labeled Compounds Others
    (R)-Nicardipine-d3 is the deuterium labeled R-Nicardipine (HY-12515C)[1].
    (R)-Nicardipine-d3
  • HY-141511
    Coppersensor 1
    Maximum Cited Publications
    6 Publications Verification

    Fluorescent Dye Neurological Disease Cancer
    Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases [1].
    Coppersensor 1
  • HY-P99454

    ABBV-838

    Antibody-Drug Conjugates (ADCs) Cancer
    Azintuxizumab vedotin (ABBV-838) is an antibody–drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells [1].
    Azintuxizumab vedotin
  • HY-16276
    Osilodrostat
    4 Publications Verification

    LCI699

    Mineralocorticoid Receptor Inflammation/Immunology Cancer
    Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS) .
    Osilodrostat
  • HY-16276A
    Osilodrostat phosphate
    4 Publications Verification

    LCI699 phosphate

    Mineralocorticoid Receptor Cancer
    Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) .
    Osilodrostat phosphate
  • HY-B1692
    L-Methionine-DL-sulfoximine
    1 Publications Verification

    MSX; MSO

    Glutaminase Neurological Disease
    L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) .
    L-Methionine-DL-sulfoximine
  • HY-137005

    Topoisomerase Apoptosis Cancer
    CS1 is a potent DNA Topo II α inhibitor. CS1 displays broad-spectrum in vitro antitumor effects, low toxicity in vivo and potential anti-multidrug resistance capabilities. CS1 leads to DNA damage, cell cycle arrest at G2/M phase and apoptosis [1].
    CS1
  • HY-106950CS1

    Diphosphofructose-2-13C (sodium); Esafosfan-2-13C (sodium); FDP-2-13C (sodium)

    Isotope-Labeled Compounds Endogenous Metabolite Others
    Fosfructose-2- 13C (sodium) is the 13C labeled Fosfructose[1].
    Fosfructose-2-13C sodium
  • HY-B0311CS1

    Isotope-Labeled Compounds Others
    (Rac)-Carbidopa-d5 is a deuterium labeled compound.
    (Rac)-Carbidopa-d5
  • HY-P1816

    Integrin Cancer
    The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models [1].
    Fibronectin CS1 Peptide

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