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Creatinine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amylases (1) Apoptosis (1) Endogenous Metabolite (16) Fluorescent Dye (1) Glucosidase (1) Glutaminase (1) Isotope-Labeled Compounds (1) NADPH Oxidase (2) Platelet-activating Factor Receptor (PAFR) (1) Reactive Oxygen Species (1) SARS-CoV (1)
By Research Areas:	Cancer (5) Endocrinology (1) Inflammation/Immunology (8) Metabolic Disease (18) Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

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Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0504

*Creatinine* 5 Publications Verification NSC13123	Endogenous Metabolite	Metabolic Disease Cancer
Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles.

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d₃	Endogenous Metabolite	Metabolic Disease Cancer
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-B0504S2

Creatinine-d5 NSC13123-d₅	Endogenous Metabolite	Metabolic Disease
Creatinine-d₅ is the deuterium labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-P2838

Creatininase, Microorganism Creatinine amidohydrolase; CAH	Endogenous Metabolite	Metabolic Disease
Creatininase, Microorganism (Creatinine amidohydrolase; CAH), namely creatinine amidohydrolase, from Pseudomonas putida, is a homohexameric enzyme commonly used in biochemical research. Creatininase acts on carbon-nitrogen bonds other than peptide bonds, and can catalyze the hydrolysis of creatinine to creatine, which can then be metabolized by creatinase to urea and sarcosine .

HY-B0504S1

Creatinine-13C NSC13123-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Creatinine- ¹³C is the ¹³C-labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-W010973

*5-Hydroxytryptamine creatinine* sulfate monohydrate**	Endogenous Metabolite	Metabolic Disease
5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite.

HY-115762

*4-Hydroxytryptamine creatinine* sulfate**	Endogenous Metabolite	Neurological Disease
4-Hydroxytryptamine creatinine sulfate, a tryptamine derivative, is a neurotransmitter agonist .

HY-B0504R

Creatinine (Standard)	Endogenous Metabolite	Metabolic Disease Cancer
Creatinine (Standard) is the analytical standard of Creatinine. This product is intended for research and analytical applications. Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles.

HY-P2815

Creatinine deiminase	Others	Others
Creatinine deiminase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W010973S

*5-Hydroxytryptamine-d4 creatinine* sulfate monohydrate**	Endogenous Metabolite	Metabolic Disease
5-Hydroxytryptamine-d₄ creatinine sulfate monohydrate is the deuterium labeled 5-Hydroxytryptamine creatinine sulfate monohydrate. 5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite.

HY-111314

NZ 419 5-Hydroxy-1-methylhydantoin	Reactive Oxygen Species	Inflammation/Immunology
NZ 419 (5-Hydroxy-1-methylhydantoin) is a metabolite of creatinine and an antioxidant with oral activity, which has the ability to scavenge hydroxyl radicals (•OH). NZ 419 can inhibit the progression of chronic kidney disease (CKD) in rats .

HY-P2893B

Creatinase, microorganism Creatine amidinohydrolase, microorganism	Endogenous Metabolite	Metabolic Disease
Creatine amidinohydrolase, microorganism is a hydrolytic enzyme that catalyzes the hydrolysis of creatine into creatinine and urea, playing a crucial role in the measurement of creatinine concentration. Creatine amidinohydrolase, microorganism can be used in the development of biosensors for measuring serum creatinine levels .

HY-113382

N-Methylhydantoin 1-Methylhydantoin	Endogenous Metabolite	Others
N-Methylhydantoin is a product of degradation of creatinine by bacteria.

HY-P2893A

Creatinase (Recombinant) Creatine amidinohydrolase	Endogenous Metabolite	Metabolic Disease
Creatinase (Recombinant) is a hydrolase responsible for catalyzing the hydrolysis of creatine (HY-W010388) into sarcosine (HY-101037) and urea (HY-Y0271). Creatinase (Recombinant) can be used in conjunction with creatinine deiminase (HY-P2838) and sarcosine oxidase (HY-P2861) in an enzyme cascade reaction to measure creatinine (HY-B0504) levels in blood and urine. Creatinase (Recombinant) is the rate-limiting enzyme in this enzymatic cascade, and the enzymatic quantification of creatinine is an important method for evaluating kidney function .

HY-P2893

Creatinase, Actinobacteria Creatine amidohydrolase	Endogenous Metabolite	Others
Creatinase, Actinobacteria (Creatine amidohydrolase) is a hydrolase that catalyzes the hydrolysis of creatine into sarcosine and urea, and plays an important role in the enzymatic determination of creatinine concentration .

HY-101410

SDMA Symmetric dimethylarginine; NG,NG'-Dimethyl-L-arginine	Endogenous Metabolite	Inflammation/Immunology
SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.

HY-B0235

Trichlormethiazide	Others	Metabolic Disease
Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .

HY-B0235A

Trichlormethiazide sodium	Others	Metabolic Disease
Trichlormethiazide sodium is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide sodium increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .

HY-101410R

SDMA (Standard)	Endogenous Metabolite	Inflammation/Immunology
SDMA (Standard) is the analytical standard of SDMA. This product is intended for research and analytical applications. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.

HY-161429

Antidiabetic agent 5	Amylases Glucosidase	Metabolic Disease
Antidiabetic agent 5 (compound S1) is a antidiabetic agent. Antidiabetic agent 5 inhibits the activity of α-glucosidase and α-amylase with IC₅₀ values of 3.91, 8.89 µM, respectively. Antidiabetic agent 5 decreases sugar levels. Antidiabetic agent 5 has the potential for the research of type-II diabetes .

HY-B0235R

Trichlormethiazide (Standard)	Others	Metabolic Disease
Trichlormethiazide (Standard) is the analytical standard of Trichlormethiazide. This product is intended for research and analytical applications. Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .

HY-100446

NTU281	Glutaminase Apoptosis	Metabolic Disease Inflammation/Immunology
NTU281 is a potent transglutaminase-2 inhibitor. NTU281 can reduce the increases in serum creatinine and albuminuria in diabetic rats. NTU281 can also reduce glomerular collagen I accumulation, Hic-5 and α-SMA expression, and apoptosis. NTU281 can be used for researching glomerulosclerosis caused by diabetes .

HY-P99901

Sibeprenlimab VIS649	SARS-CoV	Inflammation/Immunology Cancer
Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand (APRIL). Sibeprenlimab suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) .

HY-119035

R-75317	Platelet-activating Factor Receptor (PAFR)	Inflammation/Immunology
R-75317 is a specific platelet-activating factor (PAF) antagonist. R-75317 can prevent the decline in creatinine clearance (Ccr) in a rat model of glomerulonephritis induced by the injection of antibodies extracted from rabbits against rat glomerular basement membrane (GBM) antigens, delay the onset of proteinuria, and improve glomerular hypertrophy, mesangial matrix proliferation, and interstitial fibrosis. R-75317 may be useful in the study of glomerulonephritis .

HY-15344

Ketone monoester 2 Publications Verification	Others	Neurological Disease Metabolic Disease
Ketone monoester is an orally available ketone monoester that serves as a source of nutritional ketones. Ketone monoester increases plasma beta-hydroxybutyrate, acetoacetate, blood glucose, blood sodium, and blood creatinine levels in mouse models. Ketone monoester has the potential to improve athletic performance and endurance in animals. Ketone monoester partially prevents myasthenia in septic mice. Ketone monoester may also be used to study Parkinson's disease or diabetes .

HY-120801

APX-115 1 Publications Verification Ewha-18278	NADPH Oxidase	Metabolic Disease Inflammation/Immunology
APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with K_i values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury .

HY-120801A

APX-115 free base 1 Publications Verification Ewha-18278 free base; Isuzinaxib free base	NADPH Oxidase	Inflammation/Immunology Endocrinology
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with K_i values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base effectively prevents kidney injury .

HY-W040144

Bromocresol green	Fluorescent Dye	Others
Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells .

HY-E70410

NAD Synthetase NAD+ Synthetase; Nicotinamide adenine dinucleotide synthetase	Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
NAD synthetase is responsible for the final step in the synthesis of nicotinamide adenine dinucleotide (NAD). The K_m values for NAD, ATP, and ammonia of NAD synthetase from Escherichia coli are 200 μM, 11 μM, and 0.65 μM, respectively, while the K_m values for NAD, ATP, and ammonia of NAD synthetase from yeast are 170 μM, 190 μM, and 64 μM, respectively. NAD synthetase can be used for enzymatic assays to determine ATP, ammonia, urea, or creatinine, and is also suitable for enzymatic cycling methods. Additionally, NAD synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative diseases .

Cat. No.	Product Name	Type

HY-W040144

Bromocresol green	Indicators
Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells .

Bromocresol green

Indicators

Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells .

Cat. No.	Product Name	Target	Research Area

HY-P99901

Sibeprenlimab VIS649	SARS-CoV	Inflammation/Immunology Cancer
Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand (APRIL). Sibeprenlimab suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0504

*Creatinine* 5 Publications Verification NSC13123	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease markers Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles.

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d₃	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-W010973

*5-Hydroxytryptamine creatinine* sulfate monohydrate**	Natural Products Monophenols Classification of Application Fields Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite.

HY-115762

*4-Hydroxytryptamine creatinine* sulfate**	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Indole Alkaloids	Endogenous Metabolite
4-Hydroxytryptamine creatinine sulfate, a tryptamine derivative, is a neurotransmitter agonist .

HY-113382

N-Methylhydantoin 1-Methylhydantoin	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Methylhydantoin is a product of degradation of creatinine by bacteria.

HY-101410

SDMA Symmetric dimethylarginine; NG,NG'-Dimethyl-L-arginine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other disease Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.

HY-B0504R

Creatinine (Standard)	Infection Structural Classification Natural Products Microorganisms Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Endogenous Metabolite
Creatinine (Standard) is the analytical standard of Creatinine. This product is intended for research and analytical applications. Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles.

HY-101410R

SDMA (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite	Endogenous Metabolite
SDMA (Standard) is the analytical standard of SDMA. This product is intended for research and analytical applications. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.

Cat. No.	Product Name	Chemical Structure

HY-B0504S

Creatinine-d3 3 Publications Verification
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-B0504S2

Creatinine-d5
Creatinine-d₅ is the deuterium labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-B0504S1

Creatinine-13C
Creatinine- ¹³C is the ¹³C-labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-W010973S

*5-Hydroxytryptamine-d4 creatinine* sulfate monohydrate**
5-Hydroxytryptamine-d₄ creatinine sulfate monohydrate is the deuterium labeled 5-Hydroxytryptamine creatinine sulfate monohydrate. 5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite.

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Creatinine

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

NaturalProducts

Isotope-Labeled Compounds

Natural
Products