Search Result
Results for "
D13
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
82
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W514721
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- HY-124819
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Bacterial
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Infection
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D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively . D13-9001 exhibits antibiotic activities .
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- HY-17563S3
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Deoxyguanosine-d13; Guanine deoxyriboside-d13
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-33672S
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N-Phenylcarbazole-d13
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Isotope-Labeled Compounds
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Others
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9-Phenylcarbazole-d13 (N-Phenylcarbazole-d13) is the deuterium labeled 9-Phenylcarbazole (HY-33672) .
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- HY-D0184S4
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Deoxycytidine-d13; Cytosine deoxyriboside-d13; Deoxyribose cytidine-d13
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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2'-Deoxycytidine-d13 (Deoxycytidine-d13; Cytosine deoxyriboside-d13; Deoxyribose cytidine-d13) is deuterium labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-W127656S1
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- HY-150779S
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- HY-I0357S
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Hexyl chloroformate-d13; Hexyloxycarbonyl-D13 chloride
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Isotope-Labeled Compounds
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Others
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Hexyl chlorocarbonate-d13 is the deuterium labeled Hexyl chlorocarbonate[1].
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- HY-W392933S5
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Thymidine-5'-phosphate-d13 dilithium
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Isotope-Labeled Compounds
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Others
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Thymidine 5'-monophosphate-d13 (Thymidine-5'-phosphate-d13) dilithium is deuterium labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-144245S
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- HY-B0282AS2
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- HY-107372S3
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- HY-W011873S1
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Endogenous Metabolite
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Neurological Disease
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Palmitoleic acid-d13 is the deuterium labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats.
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- HY-W392933S1
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Thymidine-5'-phosphate-15N2,d13 dilithium
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Isotope-Labeled Compounds
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Others
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Thymidine 5'-monophosphate- 15N2,d13 (Thymidine-5'-phosphate- 15N2,d13) dilithium is deuterium and 15N labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-B0228S12
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- HY-B0158S8
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Cytosine β-D-riboside-d13; Cytosine-1-β-D-ribofuranoside-d13
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Nucleoside Antimetabolite/Analog
Endogenous Metabolite
Isotope-Labeled Compounds
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Neurological Disease
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Cytidine-d13 (Cytosine β-D-riboside-d13; Cytosine-1-β-D-ribofuranoside-d13) is deuterium labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
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- HY-N0097S5
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DL-Guanosine-d13; Vernine-d13
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Isotope-Labeled Compounds
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Infection
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Guanosine-d13 (DL-Guanosine-d13) is a deuterium of Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
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- HY-W012626S
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- HY-N2341S
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AMPK
PPAR
Glucokinase
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Metabolic Disease
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Palmitelaidic acid-d13 is the deuterium labeled Palmitelaidic Acid. Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue.
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- HY-113427S
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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trans-Vaccenic acid-d13 is deuterium labeled trans-Vaccenic acid. trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid (CLA) at the tissue level .
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- HY-19883S
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- HY-B1337S3
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Endogenous Metabolite
Cholinesterase (ChE)
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Others
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Choline-d13 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
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- HY-W040329S2
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- HY-113400S3
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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Cytidine diphosphate-d13 dilithium is deuterium labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
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- HY-W040329S3
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- HY-10274S
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Isotope-Labeled Compounds
Thrombin
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Cardiovascular Disease
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Dabigatran etexilate-d13 is the deuterium labeled Dabigatran etexilate. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran. Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].
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- HY-113427AS
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Antibiotic
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Cancer
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cis-Vaccenic acid-d13 is the deuterium labeled cis-Vaccenic acid. cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate[1], acts a potential fetal hemoglobin inducer[2].
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- HY-113066S2
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GDP-d13 dilithium
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Isotope-Labeled Compounds
Endogenous Metabolite
Potassium Channel
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Inflammation/Immunology
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Guanosine 5'-diphosphate-d13 (GDP-d13) dilithium is deuterium labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
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- HY-N6810S
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Bacterial
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Cancer
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Thymol-d13 is the deuterium labeled Thymol[1]. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects[2].
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- HY-109506S5
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129Y83-d13
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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DPPC-d13 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
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- HY-W032022S
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Isotope-Labeled Compounds
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Others
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1-Hexanol-d13 is the deuterium labeled 1-Hexanol[1]. 1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[2]. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism[3].
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- HY-D0858S
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Isotope-Labeled Compounds
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Others
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MES-d13 is the deuterium labeled MES. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .
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- HY-B0817S
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Parasite
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Infection
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Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].
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- HY-109541S3
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DMPC-d13
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Isotope-Labeled Compounds
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Others
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1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
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- HY-W653921
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Isotope-Labeled Compounds
Enterovirus
Photosystem II
Influenza Virus
Bacterial
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Infection
Cancer
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Tenuazonic acid-d13 is deuterium labeled Tenuazonic acid. Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD50 is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a photosystem II (PSII) inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer .
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- HY-W040193S6
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1,2-Distearoyl-sn-glycero-3-PC-d13; DSPC-d13
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Isotope-Labeled Compounds
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Others
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1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly
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- HY-163370
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- HY-168715
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SHP2
Apoptosis
MAPKAPK2 (MK2)
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Cancer
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SHP2-IN-33 (Compound D13) is an allosteric inhibitor of SHP2 with an IC50 of 1.2 μM. In cellular studies, SHP2-IN-33 demonstrates antiproliferative activity with an IC50 of 38 μM against Huh7 cells by arresting the G0/G1 cell cycle, promoting apoptosis (Apoptosis), and suppressing the MAPK signaling pathway. In an in vivo Huh7 xenograft mouse model, SHP2-IN-33 exhibits significant antitumor activity and favorable pharmacokinetics, including 54% oral bioavailability and a half-life of 10.57 hours. SHP2-IN-33 is a promising compound for studying tumor diseases associated with SHP2 .
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- HY-18572S
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2,4-Dichlorophenoxyacetic acid-13C6
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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2,4-D- 13C6 is the 13C-labeled 2,4-D. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[1].
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- HY-W128417S
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DmPABr-13C2,d6
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Isotope-Labeled Compounds
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Others
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4-(Dimethylamino)phenacyl bromide- 13C2,d6 (DmPABr- 13C2,d6) is 13C-labeled 4-(Dimethylamino)phenacyl bromide (HY-W128417) .
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- HY-W769279
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- HY-B0579S3
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Cyclosporine A-13C2,d4; Ciclosporin A-13C2,d4; CsA-13C2,d4
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Isotope-Labeled Compounds
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Inflammation/Immunology
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Cyclosporin A- 13C2,d4 (Cyclosporine A- 13C2,d4; Ciclosporin A- 13C2,d4) is a 13C labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .
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- HY-W048482S
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DMT-2'O-TBDMS-rU phosphoramidite-13C2,d1
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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rU Phosphoramidite- 13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite- 13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-B1659S
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- HY-B1912S1
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- HY-166878S
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- HY-17530S
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- HY-B0389S
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- HY-W766769
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- HY-144150S
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- HY-144427S
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- HY-W005355S10
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- HY-Y0504S
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Endogenous Metabolite
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Metabolic Disease
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Trimethylammonium chloride- 13C3,d9 is the deuterium and 13C labeled Trimethylammonium chloride[1]. Trimethylammonium chloride is an endogenous metabolite.
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- HY-132644S1
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- HY-W005355S
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- HY-113263S1
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- HY-150629S
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- HY-W654343
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- HY-143943S
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- HY-143784S
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- HY-W006057AS3
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- HY-W006057AS2
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- HY-113254S1
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- HY-113254S
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- HY-N7092S13
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- HY-W400722
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- HY-W092298S
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- HY-90009AS
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- HY-144509S
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Endogenous Metabolite
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Metabolic Disease
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l-α-tocopherol acetate- 13C4,d6 is the 13C- and deuterium-labeled l-α-tocopherol acetate. l-α-tocopherol acetate is a natural tocopherol and has potent antioxidant activities[1].
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- HY-W015883S2
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Endogenous Metabolite
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Metabolic Disease
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Fumaric acid- 13C2,d2 is the deuterium and 13C labeled Fumaric acid[1]. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite[2].
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- HY-B0782S1
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- HY-128417S5
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- HY-W018587S
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- HY-W337886S
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- HY-N0379S18
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- HY-10466S1
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BMS-790052-13C2,d6; EBP 883-13C2,d6
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Isotope-Labeled Compounds
HCV
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Infection
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Daclatasvir- 13C2,d6 (BMS-790052- 13C2,d6) is 13C and deuterium labeled Daclatasvir. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively .
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- HY-B0389S22
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Glucose-13C2,d2; D-(+)-Glucose-13C2,d2; Dextrose-13C2,d2
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Endogenous Metabolite
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Metabolic Disease
Cancer
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D-Glucose- 13C2,d2 is the deuterium and 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical si
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- HY-W042357S3
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Isotope-Labeled Compounds
DNA/RNA Synthesis
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Others
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Ac-rC Phosphoramidite- 13C2,d1 is deuterium and 13C-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
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- HY-B1278AS
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Vitamin E acetate-13C4,d6
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Isotope-Labeled Compounds
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Inflammation/Immunology
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DL-α-Tocopherol acetate- 13C4,d6 is the deuterium and 13C labeled DL-α-Tocopherol acetate[1]. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition[2][3].
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- HY-W269693S
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Isotope-Labeled Compounds
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Others
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5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione- 13C3,d5 is the deuterium and 13C labeled 5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione[1].
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- HY-W006057AS13
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Endogenous Metabolite
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Others
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Sodium 3-methyl-2-oxobutanoate- 13C4,d3 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
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- HY-B0495S
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LTG-13C3,d3; BW430C-13C3,d3
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Sodium Channel
Autophagy
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Neurological Disease
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Lamotrigine- 13C3,d3 is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].
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- HY-B0151S1
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3β-Hydroxy-5-pregnen-20-one-13C2,d2
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Isotope-Labeled Compounds
Autophagy
Cannabinoid Receptor
Endogenous Metabolite
TRP Channel
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Neurological Disease
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Pregnenolone- 13C2,d2 is the deuterium and 13C labeled Pregnenolone (HY-B0151). Pregnenolone is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[1][2][3][4].
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- HY-W243018S
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Isotope-Labeled Compounds
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Others
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1,2:5,6-Di-O-isopropylidene-a-D-glucofuranose-1,2,3,4,5,6- 13C6 is the 13C labeled (3aS,5R,6R,6aS)-5-((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol[1].
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- HY-B0712S1
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Ro 13-9904-13C2,d3 triethylammonium salt
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Antibiotic
Aurora Kinase
GSK-3
Bacterial
Isotope-Labeled Compounds
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Infection
Inflammation/Immunology
Cancer
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Ceftriaxone- 13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
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- HY-110189S
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3β-Hydroxy-5-pregnen-20-one monosulfate (sodium)-13C2,d2
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Cannabinoid Receptor
TRP Channel
Endogenous Metabolite
Autophagy
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Neurological Disease
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Pregnenolone monosulfate (sodium)- 13C2,d2 is the 13C- and deuterium labeled Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium salt is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
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- HY-109541S3
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DMPC-d13
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Drug Delivery
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1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
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Optimized version of product available:
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Product Name |
Chemical Structure |
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- HY-B0282AS2
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Acetylcholine-d13 (bromide) is the deuterium labeled Acetylcholine bromide[1].
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- HY-17563S3
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2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-33672S
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9-Phenylcarbazole-d13 (N-Phenylcarbazole-d13) is the deuterium labeled 9-Phenylcarbazole (HY-33672) .
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- HY-D0184S4
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2'-Deoxycytidine-d13 (Deoxycytidine-d13; Cytosine deoxyriboside-d13; Deoxyribose cytidine-d13) is deuterium labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-W127656S1
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Choline-d13 (bromide) is the deuterium labeled Choline bromide[1].
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- HY-150779S
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Choline-d13 (sulfate) is the deuterium labeled Choline sulfate[1].
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- HY-I0357S
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Hexyl chlorocarbonate-d13 is the deuterium labeled Hexyl chlorocarbonate[1].
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- HY-W392933S5
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Thymidine 5'-monophosphate-d13 (Thymidine-5'-phosphate-d13) dilithium is deuterium labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-144245S
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5-Hydroxyl ZLN005-d13 is the deuterium labeled 5-Hydroxyl ZLN005[1]。
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- HY-107372S3
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Uridine triphosphate-d13 (UTP-d13 dilithium; Uridine 5'-triphosphate-d13) dilithium is deuterium labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.
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- HY-W011873S1
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Palmitoleic acid-d13 is the deuterium labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats.
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- HY-W392933S1
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Thymidine 5'-monophosphate- 15N2,d13 (Thymidine-5'-phosphate- 15N2,d13) dilithium is deuterium and 15N labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-B0228S12
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Adenosine-d13 (Adenine riboside-d13; D-Adenosine-d13) is deuterium labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
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- HY-B0158S8
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Cytidine-d13 (Cytosine β-D-riboside-d13; Cytosine-1-β-D-ribofuranoside-d13) is deuterium labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
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- HY-N0097S5
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Guanosine-d13 (DL-Guanosine-d13) is a deuterium of Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
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- HY-W012626S
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2-Ethyl-6-methylaniline-d13 is the deuterium labeled 2-Ethyl-6-methylaniline[1].
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- HY-N2341S
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Palmitelaidic acid-d13 is the deuterium labeled Palmitelaidic Acid. Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue.
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- HY-113427S
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trans-Vaccenic acid-d13 is deuterium labeled trans-Vaccenic acid. trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid (CLA) at the tissue level .
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- HY-19883S
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Lusutrombopag-d13 is deuterium labeled Lusutrombopag. Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.
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- HY-B1337S3
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Choline-d13 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
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- HY-W040329S2
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2'-Deoxyadenosine-d13 is deuterium labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-113400S3
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Cytidine diphosphate-d13 dilithium is deuterium labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
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- HY-W040329S3
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2'-Deoxyadenosine- 15N5,d13 is deuterium and 15N labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-10274S
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Dabigatran etexilate-d13 is the deuterium labeled Dabigatran etexilate. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran. Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].
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- HY-113427AS
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cis-Vaccenic acid-d13 is the deuterium labeled cis-Vaccenic acid. cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate[1], acts a potential fetal hemoglobin inducer[2].
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- HY-113066S2
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Guanosine 5'-diphosphate-d13 (GDP-d13) dilithium is deuterium labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
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- HY-N6810S
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Thymol-d13 is the deuterium labeled Thymol[1]. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects[2].
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- HY-109506S5
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DPPC-d13 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
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- HY-W032022S
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1-Hexanol-d13 is the deuterium labeled 1-Hexanol[1]. 1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[2]. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism[3].
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- HY-D0858S
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MES-d13 is the deuterium labeled MES. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .
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- HY-B0817S
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Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].
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- HY-109541S3
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1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
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- HY-W653921
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Tenuazonic acid-d13 is deuterium labeled Tenuazonic acid. Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD50 is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a photosystem II (PSII) inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer .
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- HY-W040193S6
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1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly
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- HY-18572S
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2,4-D- 13C6 is the 13C-labeled 2,4-D. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[1].
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- HY-W128417S
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4-(Dimethylamino)phenacyl bromide- 13C2,d6 (DmPABr- 13C2,d6) is 13C-labeled 4-(Dimethylamino)phenacyl bromide (HY-W128417) .
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- HY-W769279
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Felodipine- 13C4,d3 is 13C labeled Felodipine .
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- HY-B0579S3
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Cyclosporin A- 13C2,d4 (Cyclosporine A- 13C2,d4; Ciclosporin A- 13C2,d4) is a 13C labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .
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- HY-W048482S
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rU Phosphoramidite- 13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite- 13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-B1659S
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Glycerol- 13C3,d8 is the deuterium and 13C labeled Glycerol[1].
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- HY-B1912S1
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Amidosulfuron- 13C2,d6 is the 13C- and deuterium labeled Amidosulfuron[1].
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- HY-166878S
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SAR107375E impurity 13-d8 is deuterium labeled SAR107375E impurity 138 .
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- HY-17530S
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Aldicarb sulfone- 13C2,d3 is the deuterium and 13C labeled Aldicarb sulfone[1].
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- HY-B0389S
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D-Glucose- 13C6,d7 is the deuterium and 13C labeled D-Glucose[1].
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- HY-W766769
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Cyproterone Acetate- 13C2,d3 is 13C-labeled Cyproterone Acetate (HY-13604) .
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- HY-144150S
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Pelubiprofen impurity 2- 13C2,d6 is the 13C- and deuterium labeled Pelubiprofen impurity 2[1].
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- HY-144427S
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Vitamin E- 13C2,d6 is a 13C-labeled and deuterium labeled Vitamin E[1].
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- HY-W005355S10
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Sodium 2-oxobutanoate- 13C4,d2 is the deuterium and 13C labeled Sodium 2-oxobutanoate[1].
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- HY-Y0504S
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Trimethylammonium chloride- 13C3,d9 is the deuterium and 13C labeled Trimethylammonium chloride[1]. Trimethylammonium chloride is an endogenous metabolite.
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- HY-132644S1
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3-Demethyl Thiocolchicine--- 13C2,d6 is 13C and deuterated labeled 3-Demethyl Thiocolchicine-.
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- HY-W005355S
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Sodium 2-oxobutanoate- 13C4,d2 (hydrate) is the deuterium and 13C labeled Sodium 2-oxobutanoate hydrate[1].
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- HY-113263S1
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17α-Hydroxypregnenolone- 13C2,d2 is the deuterium and 13C labeled 17α-Hydroxypregnenolone[1].
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- HY-150629S
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2-Ketobutyric acid- 13C4,3,3-d2 sodium salt hydrate is the 13C labeled 2-Ketobutyric acid sodium salt hydrate[1].
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- HY-W654343
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D-Erythro-sphingosine-1-phosphate- 13C2,d2 is 13C labeled D-Erythro-sphingosine-1-phosphate .
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- HY-143943S
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Felodipine 3,5-dimethyl ester- 13C2,d6 is the 13C- and deuterium labeled Felodipine 3,5-dimethyl ester[1].
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- HY-143784S
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C14 Benzalkonium-1 acid- 13C2,d11 (chloride) is the deuterium and 13C labeled C14 Benzalkonium-1 acid chloride[1].
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- HY-W006057AS3
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Sodium 3-methyl-2-oxobutanoate- 13C2,d4 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate[1].
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- HY-W006057AS2
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Sodium 3-methyl-2-oxobutanoate- 13C4,d4 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate[1].
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- HY-113254S1
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13,14-Dihydro-15-keto-PGE2-d9 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2[1].
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- HY-113254S
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13,14-Dihydro-15-keto-PGE2-d4 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2[1].
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- HY-N7092S13
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D-Fructose- 13C6,d7 is the deuterium and 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
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- HY-W400722
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Sodium 3-methyl-2-oxobutanoate- 13C5,d1 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate[1].
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- HY-W092298S
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Methyl 4-(2-hydroxyethyl)benzoate- 13C6,d2 is 13C and deuterated labeled Methyl 4-(2-hydroxyethyl)benzoate (HY-W092298).
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- HY-90009AS
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Tadalafil- 13C2,d3 is 13C and deuterated labeled Tadalafil (HY-90009A). Tadalafil (IC-351) is a PDE5 inhibitor with an IC50 value of 1.8 nM.
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- HY-144509S
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l-α-tocopherol acetate- 13C4,d6 is the 13C- and deuterium-labeled l-α-tocopherol acetate. l-α-tocopherol acetate is a natural tocopherol and has potent antioxidant activities[1].
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- HY-W015883S2
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Fumaric acid- 13C2,d2 is the deuterium and 13C labeled Fumaric acid[1]. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite[2].
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- HY-B0782S1
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Acetazolamide- 13C2,d3 is the 13C- and deuterium labeled Acetazolamide. Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX[1]. Diuretic effects[4].
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- HY-128417S5
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alpha-D-glucose- 13C6,d7 is deuterium and 13C-labeled alpha-D-glucose (HY-128417). alpha-D-glucose is an endogenous metabolite.
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- HY-W018587S
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Bis(2-Ethylhexyl)-tetrabromo phthalate- 13C6,d34 is 13C labeled Bis(2-ethylhexyl) 3,4,5,6-tetrabromophthalate .
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- HY-W337886S
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2-Ethylhexyl 2,3,4,5-tetrabromobenzoate- 13C6,d17 is 13C labeled 2-Ethylhexyl 2,3,4,5-tetrabromobenzoate .
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- HY-N0379S18
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D-mannose- 13C6,d7 is the deuterium and 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
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- HY-10466S1
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Daclatasvir- 13C2,d6 (BMS-790052- 13C2,d6) is 13C and deuterium labeled Daclatasvir. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively .
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- HY-B0389S22
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D-Glucose- 13C2,d2 is the deuterium and 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical si
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- HY-W042357S3
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Ac-rC Phosphoramidite- 13C2,d1 is deuterium and 13C-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
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- HY-B1278AS
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DL-α-Tocopherol acetate- 13C4,d6 is the deuterium and 13C labeled DL-α-Tocopherol acetate[1]. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition[2][3].
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- HY-W269693S
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5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione- 13C3,d5 is the deuterium and 13C labeled 5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione[1].
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- HY-W006057AS13
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Sodium 3-methyl-2-oxobutanoate- 13C4,d3 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
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- HY-B0495S
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Lamotrigine- 13C3,d3 is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].
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- HY-B0151S1
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Pregnenolone- 13C2,d2 is the deuterium and 13C labeled Pregnenolone (HY-B0151). Pregnenolone is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[1][2][3][4].
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- HY-W243018S
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1,2:5,6-Di-O-isopropylidene-a-D-glucofuranose-1,2,3,4,5,6- 13C6 is the 13C labeled (3aS,5R,6R,6aS)-5-((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol[1].
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- HY-B0712S1
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Ceftriaxone- 13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
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- HY-110189S
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Pregnenolone monosulfate (sodium)- 13C2,d2 is the 13C- and deuterium labeled Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium salt is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
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