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Results for "

Ehrlich ascites tumor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (4) Antibiotic (8) Apoptosis (4) Autophagy (4) Bacterial (6) DNA/RNA Synthesis (8) Drug Derivative (1) Endonuclease (1) Fluorescent Dye (1) Interleukin Related (1) NO Synthase (1) Topoisomerase (4)
By Research Areas:	Cancer (12) Infection (7) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (4)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Targets Recommended: TNF Receptor BRK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0085

DiSC3(5) 5+ Cited Publications	Fluorescent Dye	Others
DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

HY-136110

2-Keto-D-galactose D-Galactosone	DNA/RNA Synthesis	Cancer
2-Keto-D-galactose (D-Galactosone) inhibits DNA synthesis, and inhibits proliferation of in vitro grown Ehrlich ascites tumor cells .

HY-118327

Maleuric acid N-carbamylmaleamic acid	DNA/RNA Synthesis	Cancer
Maleuric acid has cytotoxicity on Ehrlich ascites tumor cells by preventing the entry of preprophase cells into mitosis^[1].

HY-119589

Altersolanol B Dactylarin	Antibiotic	Others
Altersolanol B (Dactylarin), a compound isolated from fungi, is structurally related to antibiotics and has been shown to induce ATP catabolism in Ehrlich ascites tumor cells.

HY-129469

Saframycin S	Antibiotic	Infection
Saframycin S is an antibiotic with a racemomycin group that exhibits inhibitory activity against Ehrlich ascites tumors. The LD₅₀ of Saframycin S in ddY mice is 3.2 mg/kg (i.p.) .

HY-129762

Yoshi-864 NSC-102627	DNA/RNA Synthesis	Cancer
Yoshi-864 (NSC-102627) is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor .

HY-157901

2,3-Dihydroxybutanoic acid 2,3-Dihydroxybutyric acid	Drug Derivative	Cancer
2,3-Dihydroxybutanoic acid is an anticancer agent that can be extracted from the leaves of Corydalis. 2,3-Dihydroxybutanoic acid has anticancer activity both in vitro and in vivo and is lethal to Ehrlich ascites tumor cells .

HY-119789

Albofungin	Antibiotic Bacterial	Infection
Albofungin (Antibiotic P-42-1) is isolated from the culture filtrate of Actinomyces tumemacerans strain INMI.P-42. Albofungin shows highly active on a wide variety of gram-positive bacteria and fungi. Albofungin shows cytotoxic to HeLa cell cultures and exhibited antitumor activity on EHRLICH ascites tumor in mice.

HY-19606

Cytogenin Antibiotic MI 43-37F11	Interleukin Related NO Synthase	Metabolic Disease Inflammation/Immunology Cancer
Cytogenin (Antibiotic MI 43-37F11) is an orally active antineoplastic antibiotic. Cytogenin regulates the inflammatory cytokine, reduces the levels of iNOS, NO and IL-6 in mouse macrophages, and exhibits antidiabetic efficacy in mice. Cytogenin inhibits growth of Ehrlich ascites tumor in mouse model .

HY-150015

4,5'-Dimethylangelicin-NHS	DNA/RNA Synthesis	Cancer
4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent .

HY-170844

MU147	Endonuclease	Cancer
MU147 is an MRE11 nuclease inhibitor and chemical probe with anticancer activity, which is lethal to Ehrlich ascites tumor cells both in vitro and in vivo. MU147 also eliminates the double-strand break repair mechanism dependent on the MRE11 nuclease activity without impairing the activation of ATM. MU147 also impairs the degradation of nascent strands of stalled replication FOX and selectively affects brca2-deficient cells .

HY-126170

Valanimycin	Antibiotic Bacterial	Infection Cancer
Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A)-sensitive), and P388/ADR (doxorubicin-resistant), with IC₅₀ of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice .

HY-13062

Daunorubicin hydrochloride Maximum Cited Publications 29 Publications Verification Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Bacterial Autophagy Apoptosis Antibiotic	Infection Neurological Disease Cancer
Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

HY-13062A

Daunorubicin Daunomycin; RP 13057; Rubidomycin	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Autophagy Bacterial Antibiotic Apoptosis	Infection Neurological Disease Cancer
Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

HY-13062R

Daunorubicin (hydrochloride) (Standard)	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Bacterial Autophagy Apoptosis Antibiotic	Infection Neurological Disease Cancer
Daunorubicin (hydrochloride) (Standard) is the analytical standard of Daunorubicin (hydrochloride). This product is intended for research and analytical applications. Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

HY-108876

Daunorubicin citrate Daunomycin(citrate); RP 13057(citrate); Rubidomycin(citrate)	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Autophagy Bacterial Antibiotic Apoptosis	Infection Neurological Disease Cancer
Daunorubicin (Daunomycin) citrate is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin citrate inhibits DNA and RNA synthesis. Daunorubicin citrate is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin citrate is also an anthracycline antibiotic. Daunorubicin citrate can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

Cat. No.	Product Name	Type

HY-D0085

DiSC3(5) 5+ Cited Publications	Fluorescent Dyes/Probes
DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

DiSC3(5)

5+ Cited Publications

Fluorescent Dyes/Probes

DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC₅₀ value is 8 μM. DiSC3(5) in the presence of Na ⁺/K ⁺-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .

Daunorubicin hydrochloride 25+ Cited Publications Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride	Infection Quinones Structural Classification Microorganisms Classification of Application Fields Anthraquinones Source classification Phenols Polyphenols Disease Research Fields	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Bacterial Autophagy Apoptosis Antibiotic
Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

Saframycin S	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic
Saframycin S is an antibiotic with a racemomycin group that exhibits inhibitory activity against Ehrlich ascites tumors. The LD₅₀ of Saframycin S in ddY mice is 3.2 mg/kg (i.p.) .

Albofungin	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Albofungin (Antibiotic P-42-1) is isolated from the culture filtrate of Actinomyces tumemacerans strain INMI.P-42. Albofungin shows highly active on a wide variety of gram-positive bacteria and fungi. Albofungin shows cytotoxic to HeLa cell cultures and exhibited antitumor activity on EHRLICH ascites tumor in mice.

Valanimycin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Antibiotic Bacterial
Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A)-sensitive), and P388/ADR (doxorubicin-resistant), with IC₅₀ of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice .

Daunorubicin Daunomycin; RP 13057; Rubidomycin	Infection Quinones Structural Classification Microorganisms Classification of Application Fields Anthraquinones Source classification Phenols Polyphenols Disease Research Fields	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Autophagy Bacterial Antibiotic Apoptosis
Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

Daunorubicin (hydrochloride) (Standard)	Quinones Structural Classification Microorganisms Anthraquinones Source classification Phenols Polyphenols	Topoisomerase DNA/RNA Synthesis ADC Cytotoxin Bacterial Autophagy Apoptosis Antibiotic
Daunorubicin (hydrochloride) (Standard) is the analytical standard of Daunorubicin (hydrochloride). This product is intended for research and analytical applications. Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor .

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