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Results for "

Enterococcus faecalis.

" in MedChemExpress (MCE) Product Catalog:

25

Inhibitors & Agonists

4

Peptides

13

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-129434A
    4aα,7α,7aα-Nepetalactone

    		Bacterial Infection
    4aα,7α,7aα-Nepetalactone exhibits antibacterial activity, and inhibits Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi and Enterococcus faecalis.
    4aα,7α,7aα-Nepetalactone
  • HY-103249
    Reutericyclin

    Reutericycline

    		 Bacterial Antibiotic Infection
    Reutericyclin (Reutericycline), a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri. Reutericyclin (Reutericycline) exhibits a broad inhibitory spectrum including Lactobacillus spp., Bacillus subtilis, B. cereus, Enterococcus faecalis, Staphylococcus aureus, and Listeria innocua .
    Reutericyclin
  • HY-172109
    DNA Gyrase-IN-15

    		DNA/RNA Synthesis Infection
    DNA Gyrase-IN-15 (Compound 11) is an antimicrobial agent and inhibitor of DHPS and DNA gyrase, with IC50s of 1.73 and 0.07 µM, respectively. DNA Gyrase-IN-15 shows antimicrobial activity against Enterococcus faecalis (MIC of 15.62 µg/mL), Acinetobacter baumannii, Enterobacter species (MIC of 7.81 µg/mL), Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus. DNA Gyrase-IN-15 also shows antibiofilm activity against Enterococcus faecalis .
    DNA Gyrase-IN-15
  • HY-P5554
    cOB1 phermone

    		Bacterial Infection
    cOB1 phermone, a bacterial sex pheromone, effectively inhibits multidrug-resistant Enterococcus faecalis V583 .
    cOB1 phermone
  • HY-129166
    UCM53

    		Bacterial Infection
    UCM53, a FtsZ inhibitor, is an antibacterial agent. UCM53 can inhibit the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis
    UCM53
  • HY-P10134
    Salivaricin B

    		Bacterial Infection
    Salivaricin B is a broad-spectrum bacteriocin produced by Lactobacillus salivarius M7, capable of inhibiting the growth of Listeria monocytogenes, Bacillus cereus, Brochothrix thermosphacta, Enterococcus faecalis, and various lactobacilli .
    Salivaricin B
  • HY-W007161
    8-Desmethoxy-8-fluoro Moxifloxacin

    		Bacterial Infection
    8-Desmethoxy-8-fluoro Moxifloxacin (Compound 07) is an antibacterial agent, and has bactericidal activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis .
    8-Desmethoxy-8-fluoro Moxifloxacin
  • HY-P5695
    GP-2B

    		Bacterial Infection
    GP-2B is an antimicrobial peptide. GP-2B shows antibacterial activity against Gram-positive strain (MIC: 8-128 μg/mL for S. aureus and Enterococcus faecalis) .
    GP-2B
  • HY-126461
    Salazinic acid

    		Bacterial Fungal Infection
    Salazinic acid has antibacterial activity against bacteria and fungi. Salazinic acid does not show antibacterial activity against Listeria monocytogenes, Pseudomonas aeruginosa, Yersinia enterocolitica, and Enterococcus faecalis, but it does have antibacterial activity against Pseudomonas aeruginosa and Salmonella typhimurium .
    Salazinic acid
  • HY-168960
    ROS inducer 8

    		Reactive Oxygen Species Bacterial Infection
    ROS inducer 8 (Compound 11g) is the inhibitor for glutathione (GSH), that induces the ROS accumulation in Enterococcus faecalis, thereby exhibiting antibacterial activity. ROS inducer 8 disrupts the biofilm, inhibits S. aureus and E. faecalis with MIC of 8 μg/mL and 2 μg/mL, exhibits post-antibiotic effect. ROS inducer 8 exhibits low hemolytic toxicity to sheep erythrocytes (HC50 > 1280 μg/mL) .
    ROS inducer 8
  • HY-N7505
    Norchelerythrine

    		Bacterial Infection
    Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL .
    Norchelerythrine
  • HY-169105
    DNA Gyrase-IN-12

    		DNA/RNA Synthesis Bacterial Infection
    DNA Gyrase-IN-12 (Compound 6d) is a DNA gyrase inhibitor. DNA Gyrase-IN-12 has Antibacterial activity and MIC value of vancomycin-intermediate S. aureus (VISA) and Enterococcus faecalis strains is between 0.031 and 0.0625 μg/mL .
    DNA Gyrase-IN-12
  • HY-N0656A
    (+)-Usnic acid
    2 Publications Verification

    		 mTOR Bacterial Autophagy Infection Inflammation/Immunology Cancer
    (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer and anti-inflammatory activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium .
    (+)-Usnic acid
  • HY-N7071A
    Maduramicin ammonium

    Maduramycin ammonium

    		 Bacterial Apoptosis Antibiotic Autophagy AMPK Eukaryotic Initiation Factor (eIF) Infection Cardiovascular Disease
    Maduramicin (Maduramycin) ammonium is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium is an oral active anticoccidial agent used in research related to Eimeria, Adenosarcina, Enterococcus faecalis, and Enterococcus disperitus infections. Maduramicin ammonium induces apoptosis (apoptosis) in chicken cardiomyocytes through both intrinsic and extrinsic pathways and also impairs autophagic flux and induces rhabdomyolysis by activating the AMPK-mediated eIF2α-ATF4 endoplasmic reticulum stress pathway .
    Maduramicin ammonium
  • HY-161263
    Antibacterial agent 182

    		Bacterial Infection
    Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL). Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses .
    Antibacterial agent 182
  • HY-N0656AR
    (+)-Usnic acid (Standard)

    		mTOR Bacterial Autophagy Cancer
    (+)-Usnic acid (Standard) is the analytical standard of (+)-Usnic acid. This product is intended for research and analytical applications. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity . (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium .
    (+)-Usnic acid (Standard)
  • HY-P5203
    Enterocin K1

    EntK1

    		 Bacterial Infection
    Enterocin K1 (EntK1) is a bacteriocin. Enterocin K1 is a ribosomal synthetic peptide. Enterocin K1 specifically targets Enterococcus faecalis via the Eep protein on the bacterial membrane. Enterocin K1 displays a potent antibacterial activity against VRE. Enterocin K1 can be used for related studies of VRE infections .
    Enterocin K1
  • HY-143326
    Antibacterial agent 83

    		Bacterial Infection
    Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes .
    Antibacterial agent 83
  • HY-W145053
    ChloraMine-T hydrate

    Sodium chloro(4-methylbenzenesulfonyl)azanide hydrate

    		 Factor Xa Bacterial Infection
    ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) is a common reagent in various synthetic processes. It has been used as a reagent in aminohydroxylation and allylic amination reactions, a nitrogen source in aziridination reactions of alkenes and alkenes, and deprotection of sulfur groups in sulfur-containing compounds. It has been used as a reagent in the synthesis of factor Xa inhibitors. ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) (0.2% w/v) is also an antimicrobial agent that kills Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Proteus mirabilis, and Enterococcus cloacae.
    ChloraMine-T hydrate
  • HY-W587957
    Gypsogenic acid

    		Bacterial Parasite Infection
    Gypsogenic acid is a triterpenoid acid that can be isolated from Miconia stenostachya and has antibacterial and trypanoidal activities. The MICs values of Gypsogenic acid for the oral bacterial pathogens Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans and sobrinus were 50-200 μg/mL. Gypsogenic acid can induce blood cortensite cleavage in isolated mice with IC50 56.6 μM .
    Gypsogenic acid
  • HY-N10561
    Wychimicin A

    		Bacterial Infection
    Wychimicin A is a spirotetronate polyketide, can be isolated from the rare actinomycete Actinocrispum wychmicini strain MI503-AF4. Wychimicin A shows strong antibacterial activity against methicillin-resistant Staphylococcus. aureus (IC50=0.125-0.5 μg/mL) and Enterococcus. faecalis/faecium (IC50=0.125-0.25 μg/mL) .
    Wychimicin A
  • HY-N10560
    Wychimicin C

    		Bacterial Infection
    Wychimicin C is a spirotetronate polyketide, can be isolated from the rare actinomycete Actinocrispum wychmicini strain MI503-AF4. Wychimicin C shows strong antibacterial activity against methicillin-resistant Staphylococcus. aureus (IC50=0.125-0.5 μg/mL) and Enterococcus. faecalis/faecium (IC50=0.125-0.25 μg/mL) .
    Wychimicin C
  • HY-130596
    DC-86-M

    		Antibiotic Bacterial Infection Cancer
    DC-86-M is an antibiotic, which can be isolated from Streptomyces luteogriseus. DC-86-M exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Vibrio anguillarum, and Proteus vulgaris, with MIC <1 μg/mL. DC-86-M exhibits antitumor activity against mouse sarcoma 180 with LD50 of 25 mg/kg .
    DC-86-M
  • HY-N6846
    10-​Isobutyryloxy-​8,​9-​epoxythymol isobutyrate

    		Bacterial Infection
    10-Isobutyryloxy-8,9-epoxythymol isobutyrate is a major constituent of Inula helenium and Inula royleana root cultures. 10-Isobutyryloxy-8,9-epoxythymol isobutyrate shows moderate antimicrobial activity against Staphylococcus aureus FDA 209 P, Staphylococcus aureus, Enterococcus faecalis, Candida albicans and Pseudomonas aeruginosa with MICs of 50, 250, 250, 250, and 1000 μg/mL, respectively .
    10-​Isobutyryloxy-​8,​9-​epoxythymol isobutyrate
  • HY-N10264
    Avrainvillamide

    (+)-Avrainvillamide; CJ-17,665

    		 Antibiotic Infection Cancer
    Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .
    Avrainvillamide

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