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Results for "

FBPase

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

4

Recombinant Proteins

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136717
    FBPase-1 inhibitor-1

    		FBPase Metabolic Disease
    FBPase-1 inhibitor-1 (compound 1) is a allosteric inhibitor of fructose-1,6-bisphosphatase (FBPase-1) .
    FBPase-1 inhibitor-1
  • HY-146725
    FBPase-IN-1

    		FBPase Metabolic Disease
    FBPase-IN-1 is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor for Type 2 diabetes (T2D) study with an IC50 of 0.22 μM. FBPase-IN-1 can reduce blood glucose levels and ameliorate glucose tolerance. FBPase-IN-1 modifies the C128 site, regulates the N125-S124-S123 allosteric pathway of FBPase and affects the catalytic activity of FBPase .
    FBPase-IN-1
  • HY-16307
    MB05032
    5 Publications Verification

    		 FBPase Metabolic Disease
    MB05032 is a special and efficacious gluconeogenesis inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM.
    MB05032
  • HY-14955
    Managlinat dialanetil

    MB06322; CS-917

    		 FBPase Metabolic Disease
    Managlinat dialanetil (MB06322) is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase) for the treatment of type 2 diabetes .
    Managlinat dialanetil
  • HY-168103
    FBPase-IN-3

    		FBPase Metabolic Disease
    FBPase-IN-3 (compound 45) is a FBPase (fructose-1,6-bisphosphatase) inhibitor with an IC50 of 2.08 μM. FBPase-IN-3 exhibits potent inhibitory activity of gluconeogenesis .
    FBPase-IN-3
  • HY-168651
    FBPase-IN-4

    		FBPase Metabolic Disease
    FBPase-IN-4 (Compound 11 n) is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor with a Ki value of 1.78 μM. FBPase-IN-4 can be used in type 2 diabetes research .
    FBPase-IN-4
  • HY-147645
    FBPase-IN-2

    		FBPase Metabolic Disease
    FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research .
    FBPase-IN-2
  • HY-16308
    FBPase-IN-5

    		Phosphatase Metabolic Disease
    MB-07729 is a potent fructose 1,6-bisphosphatase (FBPase) noncompetitive inhibitor with IC50 values of 31, 121, and 189 nM for human, monkey, and rat, respectively.
    FBPase-IN-5
  • HY-16309
    MB-07803

    		Phosphatase Metabolic Disease
    MB07803 is an orally available prodrug of a potent, noncompetitive inhibitor (MB07729) of fructose 1,6-bisphosphatase (FBPase), with EC50 of 140 nM and t1/2 of 7.6±2.9 h.
    MB-07803

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