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Results for "

MLCK

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (2) Calmodulin (3) CaMK (3) Casein Kinase (1) Myosin (12) PKA (3) PKC (3) ROCK (2) YAP (1)
By Research Areas:	Cancer (11) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (3)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1029

MLCK inhibitor peptide 18 4 Publications Verification	Myosin CaMK Autophagy	Others
MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC₅₀ of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.

HY-100932

ML-9 4 Publications Verification	Myosin	Cancer
ML-9 is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity . ML-9 inhibits inhibits MLCK, PKA and PKC activity with K_i values of 4, 32 and 54?μM, respectively . ML-9 induces autophagy by stimulating autophagosome formation and inhibiting their degradation .

HY-P3965

16-38-Thymosin β4 (cattle)	Myosin	Neurological Disease
16-38-Thymosin β4 (cattle) is a Ca ²⁺-independent *MLCK* activator with high affinity .

HY-100685

MS-444 2 Publications Verification BE-34776	Myosin	Cancer
MS-444 inhibits the activity of purified smooth muscle myosin light chain kinase (MLCK) with an IC₅₀ value of 10 μM.

HY-P10165

MLCK Peptide	Calmodulin	Metabolic Disease
MLCK Peptide is a fully reversible, high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase .

HY-P2162

Kemptamide	Myosin	Cancer
Kemptamide, a 13 amino acid fragment with a sequence corresponding to residues 11-23 of gizzard light chain. Kemptamide is a peptide substrate of myosin light-chain kinase (MLCK) .

HY-100932A

ML-9 Free Base	Myosin	Cancer
ML-9 (Free Base) is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity . ML-9 (Free Base) inhibits inhibits MLCK, PKA and PKC activity with K_i values of 4, 32 and 54 μM, respectively . ML-9 (Free Base) induces autophagy by stimulating autophagosome formation and inhibiting their degradation .

HY-120997

E6 Berbamine Berbamine p-nitrobenzoate	Calmodulin	Cancer
E6 Berbamine (Berbamine p-nitrobenzoate) is a potent calmodulin (CaM) antagonist. E6 Berbamine inhibits the activity of calmodulin (CaM)-dependent myosin light chain kinase (MLCK), with a K_i of 0.95 μM . E6 Berbamine also shows anti-leukemia activities, with an IC₅₀ of 2.13 μM in K562 cells .

HY-169183

Myokinasib-II	Myosin	Cancer
Myokinasib-II is a myosin light chain kinase (MLCK) inhibitor, which is a potential target for inflammatory diseases, cancer and other diseases. .

HY-P3965A

16-38-Thymosin β4 (cattle) (TFA)	Myosin	Neurological Disease
16-38-Thymosin β4 (cattle) TFA is a Ca ²⁺-independent *MLCK* activator with high affinity .

HY-P5998

Myosin Light Chain Kinase Substrate (smooth muscle)	Myosin	Cancer
Myosin Light Chain Kinase Substrate (smooth muscle) is a smooth muscle myosin light chain kinase (MLCK) synthetic peptide substrate .

HY-15417

ML-7 hydrochloride Maximum Cited Publications 21 Publications Verification	Myosin YAP	Cancer
ML-7 hydrochloride is a naphthalene sulphonamide derivative, potently inhibits *MLCK* (IC₅₀=300 nM). ML-7 hydrochloride also inhibits YAP/TAZ.

HY-18271

CaMKII-IN-1 5 Publications Verification	CaMK Autophagy	Inflammation/Immunology
CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC.

HY-100984

HA-100 1 Publications Verification	PKA PKC Myosin ROCK	Cancer
HA-100 is a potent protein kinase inhibitor, with IC₅₀s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 also used as a ROCK inhibitor .

HY-100984A

HA-100 hydrochloride	PKA PKC Myosin ROCK	Cancer
HA-100 hydrochloride is a potent protein kinase inhibitor, with IC₅₀s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 hydrochloride also used as a ROCK inhibitor .

HY-P1805

Calmodulin Binding Peptide 1	Calmodulin	Neurological Disease
Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca ²⁺ release .

HY-125957

A-3 hydrochloride	PKA Casein Kinase CaMK PKC	Others
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (K_i=4.3 μM), casein kinase II (K_i=5.1 μM) and myosin light chain kinase (MLCK) (K_i=7.4 μM). A-3 hydrochloride also inhibits PKC and casein kinase I with K_i values of 47 μM and 80 μM, respectively .

Cat. No.	Product Name	Target	Research Area

HY-P1029

MLCK inhibitor peptide 18 4 Publications Verification	Myosin CaMK Autophagy	Others
MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC₅₀ of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.

HY-P3965

16-38-Thymosin β4 (cattle)	Myosin	Neurological Disease
16-38-Thymosin β4 (cattle) is a Ca ²⁺-independent *MLCK* activator with high affinity .

HY-P3214

Myosin light chain kinase fragment 11-19 amide MLCK(11-19) amide	Peptides	Cancer
Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) is a substrate-specific peptide inhibitor of MLCK. Myosin light chain kinase fragment 11-19 amide inhibits hypotonicity-induced Ca ²⁺ entry. Myosin light chain kinase fragment 11-19 amide can be used in the research of human cervical cancer .

HY-P10166

MLCK Peptide, control	Peptides	Others
MLCK Peptide, control is a myosin light-chain kinase. Adding MLCK peptide to permeabilized L15 cells dramatically decreased IICR. MLCK peptide caused a reduction in the extent of IICR with no change in the affinity of IP3 for the IP3R .

HY-P10165

MLCK Peptide	Calmodulin	Metabolic Disease
MLCK Peptide is a fully reversible, high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase .

HY-P5436

*SK-MLCK* M13**	Peptides	Others
SK-MLCK M13 is a biological active peptide. (M-13 is a peptide that represents CAM-binding domain of Calmodulin (CaM) target proteins. CaM is an ubiquitous Ca2+ binding protein.)

HY-P2162

Kemptamide	Myosin	Cancer
Kemptamide, a 13 amino acid fragment with a sequence corresponding to residues 11-23 of gizzard light chain. Kemptamide is a peptide substrate of myosin light-chain kinase (MLCK) .

HY-P3965A

16-38-Thymosin β4 (cattle) (TFA)	Myosin	Neurological Disease
16-38-Thymosin β4 (cattle) TFA is a Ca ²⁺-independent *MLCK* activator with high affinity .

HY-P5998

Myosin Light Chain Kinase Substrate (smooth muscle)	Myosin	Cancer
Myosin Light Chain Kinase Substrate (smooth muscle) is a smooth muscle myosin light chain kinase (MLCK) synthetic peptide substrate .

HY-P1805

Calmodulin Binding Peptide 1	Calmodulin	Neurological Disease
Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca ²⁺ release .

Cat. No.	Compare	Product Name	Species	Source

HY-P703167

	MYLK Protein, Human (Inactive, Sf9, His, GST) MLCK1; MLCK; MYLK1	Human	Sf9 insect cells
	MYLK Protein, Human (Inactive, Sf9, His, GST) is the recombinant human-derived MYLK, expressed by Sf9 insect cells , with His, GST labeled tag. ,

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HY-P83388

	MYLK Antibody (YA3133) KMLS; KRP; MLCK; MYLK; myosin light chain kinase; smooth muscle and non-muscle isozymes; myosin light polypeptide kinase; telokin	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	MYLK Antibody (YA3133) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3133), targeting MYLK, with a predicted molecular weight of 211 kDa. MYLK Antibody (YA3133) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

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