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Results for "

NAS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) Apoptosis (1) Bacterial (7) Influenza Virus (5) Isotope-Labeled Compounds (1) mAChR (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (1) Infection (7) Inflammation/Immunology (6) Neurological Disease (4)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103156

NAS-181 dimesylate 2 Publications Verification	5-HT Receptor	Neurological Disease
NAS181 is a potent and selective antagonist of rat 5-HT_1B receptor, with a K_i of 47 nM. NAS181 shows 13-fold selectivity for r5-HT_1B over bovine 5-HT_1B receptor (K_i=630 nM). NAS181 increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT_1B autoreceptors .

HY-Y0272

Saccharin	Bacterial	Inflammation/Immunology
Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties .

HY-B1390B

Saccharin sodium hydrate	Bacterial	Inflammation/Immunology
Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties .

HY-B1390A

Saccharin sodium	Bacterial	Infection
Saccharin sodium is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties .

HY-W014395

Dithiodipropionic acid	Reactive Oxygen Species Apoptosis	Cancer
Dithiodipropionic acid can interact with CPUL1 (HY-151802, a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells .

HY-135507

NAS-181	5-HT Receptor	Neurological Disease
NAS-181 is a potent and selective rat 5-hydroxytryptamine1B (r5-HT1B) antagonist with an K_i value of 47 nM. NAS-181 increases the 5-HTP accumulation in rat brain regions .

HY-135507A

NAS-181 free base	5-HT Receptor	Neurological Disease
NAS181 free base is a potent and selective antagonist of rat 5-HT_1B receptor, with a K_i of 47 nM. NAS181 free base shows 13-fold selectivity for r5-HT_1B over bovine 5-HT_1B receptor (K_i=630 nM). NAS181 free base increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT_1B autoreceptors .

HY-B1390BR

Saccharin sodium hydrate (Standard)	Bacterial	Inflammation/Immunology
Saccharin (sodium hydrate) (Standard) is the analytical standard of Saccharin (sodium hydrate). This product is intended for research and analytical applications. Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties .

HY-Y0272R

Saccharin (Standard)	Bacterial	Inflammation/Immunology
Saccharin (Standard) is the analytical standard of Saccharin. This product is intended for research and analytical applications. Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties .

HY-B1390AR

Saccharin sodium (Standard)	Bacterial	Infection
Saccharin (sodium) (Standard) is the analytical standard of Saccharin (sodium). This product is intended for research and analytical applications. Saccharin sodium is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties .

HY-Y0272S

Saccharin-d4	Isotope-Labeled Compounds Bacterial	Inflammation/Immunology
Saccharin-d₄ is the deuterium labeled Saccharin. Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1].

HY-129150

Ganoderic acid TR	Influenza Virus	Infection
Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC₅₀ values of 10.9 and 4.6 μM, respectively .

HY-151104

Neuraminidase-IN-11	Influenza Virus	Infection
Neuraminidase-IN-11 (15e) is a potent and selective neuraminidase (NA) inhibitor with the IC₅₀ values of 4.7 nM, 8.46 nM and 1.5 nM against H1N1, H5N1 and H5N8 NAs respectively .

HY-139991

Neuraminidase-IN-3	Influenza Virus	Infection
Neuraminidase-IN-3 (compound 23d) is a potent influenza neuraminidase (NA) inhibitor with IC₅₀ values of 0.73, 0.26, and 0.63 nM against H1N1, H5N1, and H5N8 NAs, respectively .

HY-13340

VU0152100 VU152100	mAChR	Neurological Disease
VU0152100 (VU152100) is a highly selective mAChR positive allosteric modulator (permeable to the blood-brain barrier). VU0152100 reverses Amphetamine-induced hypermotility in rats and increased levels of extracellular dopamine in nucleus accumbens and caudate-putamen. VU0152100 has good research potential in psychosis and cognitive impairment associated with mental disorders such as schizophrenia .

HY-163393

Neuraminidase-IN-18	Influenza Virus	Infection
Neuraminidase-IN-18 (compound N5) is a novel polyheterocyclic neuraminidase (NA) inhibitor. Neuraminidase-IN-18 shows potency in inhibition of H5N1 NA with an IC₅₀ of 0.14 μM and 0.27 μM against the wild-type H5N1 NA and H5N1-H274Y mutant NA, respectively. Neuraminidase-IN-18 inhibits influenza virus replication by binding to NAs in cell level .

HY-N2735

7,3',4'-Trihydroxy-3-benzyl-2H-chromene	Influenza Virus	Infection Inflammation/Immunology
7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC₅₀ values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0272

Saccharin	Microorganisms Source classification	Bacterial
Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties .

HY-129150

Ganoderic acid TR	Infection Triterpenes Classification of Application Fields Terpenoids Source classification Polyporaceae Plants Disease Research Fields	Influenza Virus
Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC₅₀ values of 10.9 and 4.6 μM, respectively .

HY-N2735

7,3',4'-Trihydroxy-3-benzyl-2H-chromene	Structural Classification Leguminosae Caesalpinia sappan L. Source classification Phenols Polyphenols Plants	Influenza Virus
7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC₅₀ values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus .

HY-Y0272R

Saccharin (Standard)	Microorganisms Source classification	Bacterial
Saccharin (Standard) is the analytical standard of Saccharin. This product is intended for research and analytical applications. Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties .

Cat. No.	Product Name	Chemical Structure

HY-Y0272S

Saccharin-d4
Saccharin-d₄ is the deuterium labeled Saccharin. Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1].

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NAS

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
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