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Results for "

SGK1 inhibitor

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-142687
    SGK1-IN-4
    1 Publications Verification

    		 SGK Inflammation/Immunology
    SGK1-IN-4 (compound 17a) is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for osteoarthritis research .
    SGK1-IN-4
  • HY-18607
    SGK1-IN-1
    1 Publications Verification

    		 SGK Inflammation/Immunology
    SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM.
    SGK1-IN-1
  • HY-142686A
    SGK1-IN-3 hydrochloride

    		SGK Inflammation/Immunology
    SGK1-IN-3 hydrochloride (compound 3a) is a potent and orally active inhibitor of SGK1. The serine/threonine kinase SGK1 is an activator of the β-catenin pathway and a powerful stimulator of cartilage degradation that is found to be upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 hydrochloride has the potential for the research of osteoarthritis .
    SGK1-IN-3 hydrochloride
  • HY-135893
    SGK1-IN-2

    		SGK Inflammation/Immunology
    SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration .
    SGK1-IN-2
  • HY-15193
    EMD638683
    10+ Cited Publications

    		 SGK Metabolic Disease Cancer
    EMD638683 is a highly selective SGK1 inhibitor, with an IC50 value of 3 μM.
    EMD638683
  • HY-117357
    SI-113

    		SGK Cancer
    SI-113 is a SGK1 inhibitor, with an IC50 of 600 nM. SI113 induces autophagy .
    SI-113
  • HY-15193A
    EMD638683 R-Form
    2 Publications Verification

    		 SGK Metabolic Disease
    EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.
    EMD638683 R-Form
  • HY-15193B
    EMD638683 S-Form

    		SGK Metabolic Disease
    EMD638683 S-Form is the S-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.
    EMD638683 S-Form
  • HY-128221
    SGK1-IN-5

    		SGK Inflammation/Immunology
    SGK1-IN-5 (Compound 1) is an inhibitor for serum and glucocorticoid regulated kinase SGK 1 with an IC50 of 3 nM. SGK1-IN-5 inhibits SGK-1 dependent phosphorylation of GSK3β in U2OS cells with an IC50 of 1.4 μM. SGK1-IN-5 can be used in research about osteoarthritis or rheumatism .
    SGK1-IN-5
  • HY-142686
    SGK1-IN-3

    		SGK Inflammation/Immunology
    SGK1-IN-3 (compound 3a) is a potent and orally active inhibitor of SGK1. The serine/threonine kinase SGK1 is an activator of the β-catenin pathway and a powerful stimulator of cartilage degradation that is found to be upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 has the potential for the research of osteoarthritis .
    SGK1-IN-3
  • HY-15192
    GSK 650394
    Maximum Cited Publications
    17 Publications Verification

    		 SGK Influenza Virus Infection Cancer
    GSK 650394 is a novel SGK inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2 in the SPA assay respectively. GSK 650394 also inhibits influenza virus replication.
    GSK 650394
  • HY-143898
    PIM1-IN-4

    		Pim Cancer
    PIM1-IN-4 (Compound 8) is a potent inhibitor of PIM1. PIM1-IN-4 reveals strong inhibition of five other enzymes, i.e., SGK-1, PKA, CaMK-1, GSK3β, and MSK1. PIM1-IN-4 has the potential for the research of cancer diseases .
    PIM1-IN-4

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