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Results for "

Sacituzumab govitecan

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Inhibitory Antibodies

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132254
    Sacituzumab govitecan
    3 Publications Verification

    IMMU-132

    		 Antibody-Drug Conjugates (ADCs) TROP2 Cancer
    Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity .
    Sacituzumab govitecan
  • HY-132254A
    Sacituzumab govitecan (solution)
    3 Publications Verification

    IMMU-132 (solution)

    		 Antibody-Drug Conjugates (ADCs) TROP2 Cancer
    Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity .
    Sacituzumab govitecan (solution)
  • HY-P99045
    Sacituzumab

    		ADC Antibody TROP2 Cancer
    Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab is used for the synthesis of antibody-drug conjugates (ADC) drugs. Antibody-drug conjugates with sacituzumab (sacituzumab govitecan) (HY-132254) targeting TROP-2 have been approved for the field of triple-negative breast cancer .
    Sacituzumab
  • HY-13704
    SN-38
    Maximum Cited Publications
    42 Publications Verification

    7-Ethyl-10-hydroxycamptothecin

    		 Drug Metabolite Topoisomerase ADC Cytotoxin Autophagy Cancer
    SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) .
    SN-38
  • HY-13704R
    SN-38 (Standard)

    		Drug Metabolite Topoisomerase ADC Cytotoxin Autophagy Cancer
    SN-38 (Standard) is the analytical standard of SN-38. This product is intended for research and analytical applications. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) .
    SN-38 (Standard)

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