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Salmonella typhimurium

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Amino Acid Derivatives (1) Antibiotic (2) Bacterial (12) Dopamine Receptor (2) Drug Metabolite (1) Fungal (2) Histamine Receptor (3) Nucleoside Antimetabolite/Analog (1) Parasite (1) Toll-like Receptor (TLR) (2)
By Research Areas:	Infection (14) Inflammation/Immunology (6) Metabolic Disease (1) Neurological Disease (2)

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Biochemical Assay Reagents

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119543

O-Succinyl-L-homoserine	Amino Acid Derivatives	Others
O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .

HY-158425

Antimicrobial agent-31	Bacterial	Infection
Antimicrobial agent-31 (compound 4a) is a potent antimicrobial agent. Antimicrobial agent-31 inhibits Salmonella enterica serovar Typhimurium and E.coli with MIC values of 19.24, 11.31 µg/mL, respectively .

HY-154171

Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one	Nucleoside Antimetabolite/Analog	Others
Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one (Compound dP) exhibits mutagenicity for Escherichia coli and Salmonella typhimurium, that induces the conversion between GC and AT through replication error. eoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one is stable in Escherichia coli, and can be detected at wavelength >300 nM .

HY-D1056C3

Lipopolysaccharides, from S. enterica serotype typhimurium LPS, from Salmonella enterica (Serotype typhimurium)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from S. enterica serotype typhimurium, are a kind of lipid-polysaccharide endotoxin. Smooth Gram-negative bacteria's lipopolysaccharides are made up of three components: lipid A, core oligosaccharide, and O antigen (OAg). The O antigen is a polymer of sugar repeat units (RUs); the Wzz protein regulates the length of the O antigen in lipopolysaccharides, and the number of RUs attached to lipid A is determined by the modal value set by the Wzz protein. S. enterica typhimurium has two Wzz proteins: Wzz_ST (which makes the modal range of the O antigen between 16 and 35 RUs) and Wzz_fepE (which makes the modal value over 100 RUs). Mutating the genes corresponding to these two proteins causes the formation of short-chain O antigen chains and significantly reduces bacterial pathogenicity .

HY-N3549

Catalpin	Bacterial	Infection
Catalpin is an iridoid that can be isoalted from Catalpae Fructus.Catalpin shows mutagenic activity towards Salmonella typhimurium strain TA100 .

HY-P5734

Bactenecin 5	Bacterial	Infection
Bactenecin 5 is a bovine antibacterial peptide. Bactenecin 5 is active against Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. T, with MIC values of 12-25 μg/mL .

HY-126569

Efrotomycin	Antibiotic Bacterial	Infection
Efrotomycin is an orally active antibiotic. Efrotomycin can be isolated from the Streptomyces Lactamdurans. Efrotomycin has insignificant effect on Salmonella typhimurium quantity, duration, shedding rate, and antimicrobial susceptibility in infected pigs .

HY-W275553

4-Decanol	Others	Infection
4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of $AFB_1$ and MNNG in Salmonella typhimurium TA100 .

HY-B1852

Sulfometuron-methyl	Bacterial Fungal	Infection
Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III .

HY-N10322

2-Hydroxyemodin	Drug Metabolite	Others
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system .

HY-163292

Antibacterial agent 180	Bacterial Parasite	Infection
Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102) .

HY-17390A

Loxapine succinate	5-HT Receptor Dopamine Receptor	Infection Neurological Disease
Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages .

HY-B1852R

Sulfometuron-methyl (Standard)	Bacterial Fungal	Infection
Sulfometuron-methyl (Standard) is the analytical standard of Sulfometuron-methyl. This product is intended for research and analytical applications. Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III .

HY-141467

Propionyl CoA	Others	Metabolic Disease
Propionyl CoA serves as a common intermediate in the catabolic pathways of 1,2-propanediol and propionate in Salmonella enterica serovar Typhimurium LT2, and also functions as a precursor for 2-methylcitrate. Propionyl CoA is utilized as a substrate for the 2-methylcitrate synthase (PrpC) enzyme to synthesize 2-methylcitrate .

HY-B1568

Bromodiphenhydramine Ambodryl	Histamine Receptor Bacterial	Infection Inflammation/Immunology
Bromodiphenhydramine (Ambodryl) is a potent antihistamine with antimicrobial property. Bromodiphenhydramine inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine can be used for cutaneous allergies research .

HY-B1568A

Bromodiphenhydramine hydrochloride Ambodryl hydrochloride	Histamine Receptor Bacterial	Infection Inflammation/Immunology
Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research .

HY-B1568AR

Bromodiphenhydramine hydrochloride (Standard)	Histamine Receptor Bacterial	Infection Inflammation/Immunology
Bromodiphenhydramine (hydrochloride) (Standard) is the analytical standard of Bromodiphenhydramine (hydrochloride). This product is intended for research and analytical applications. Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research .

HY-17390AR

Loxapine succinate (Standard)	5-HT Receptor Dopamine Receptor	Infection Neurological Disease
Loxapine (succinate) (Standard) is the analytical standard of Loxapine (succinate). This product is intended for research and analytical applications. Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages .

HY-N2214

7-O-Methylaloeresin A	Bacterial	Inflammation/Immunology
7-O-Methylaloeresin A is 5-methylchromone glycoside isolated from Commiphora socotrana (Burseraceae). 7-O-Methylaloeresin A exhibits good activity against multiple agent resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mM, respectively. 7-O-Methylaloeresin A has antioxidant activities, gives IC50 values of 0.026 mM and 0.021 mM for DPPH and 2-deoxyribose degradation assay, respectively.

HY-D1056C1

Lipopolysaccharides, from S. enterica serotype enteritidis LPS, from Salmonella enterica (Serotype enteritidis)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from S. enterica serotype enteritidis is a lipopolysaccharide endotoxin that causes gastrointestinal disease in humans and can be transmitted through contaminated eggs or foods based on eggs and poultry meat products. S. enterica serotype enteritidis is capable of producing high molecular weight LPS-O antigen chains, Lipopolysaccharides, from S. enterica serotype typhimurium (HY-D1056C3) did not. S. enterica serotype enteritidis is similar to other pathogenic Salmonella. Lipopolysaccharides, from S. enterica serotype enteritidis' O antigen is associated with phage attachment in the early stages of phage infection S. Enteritidis .

HY-113795

Aldgamycin E	Antibiotic Bacterial	Infection
Aldgamycin E is a neutral macrolide antibiotic that can be derived from culture filtrates of Streptomyces lavendulae. Aldgamycin E has antibacterial activity .

Cat. No.	Product Name	Type

HY-D1056C3

Lipopolysaccharides, from S. enterica serotype typhimurium LPS, from Salmonella enterica (Serotype typhimurium)	Carbohydrates
Lipopolysaccharides, from S. enterica serotype typhimurium, are a kind of lipid-polysaccharide endotoxin. Smooth Gram-negative bacteria's lipopolysaccharides are made up of three components: lipid A, core oligosaccharide, and O antigen (OAg). The O antigen is a polymer of sugar repeat units (RUs); the Wzz protein regulates the length of the O antigen in lipopolysaccharides, and the number of RUs attached to lipid A is determined by the modal value set by the Wzz protein. S. enterica typhimurium has two Wzz proteins: Wzz_ST (which makes the modal range of the O antigen between 16 and 35 RUs) and Wzz_fepE (which makes the modal value over 100 RUs). Mutating the genes corresponding to these two proteins causes the formation of short-chain O antigen chains and significantly reduces bacterial pathogenicity .

Lipopolysaccharides, from S. enterica serotype typhimurium

LPS, from Salmonella enterica (Serotype typhimurium)

Carbohydrates

Lipopolysaccharides, from S. enterica serotype typhimurium, are a kind of lipid-polysaccharide endotoxin. Smooth Gram-negative bacteria's lipopolysaccharides are made up of three components: lipid A, core oligosaccharide, and O antigen (OAg). The O antigen is a polymer of sugar repeat units (RUs); the Wzz protein regulates the length of the O antigen in lipopolysaccharides, and the number of RUs attached to lipid A is determined by the modal value set by the Wzz protein. S. enterica typhimurium has two Wzz proteins: Wzz_ST (which makes the modal range of the O antigen between 16 and 35 RUs) and Wzz_fepE (which makes the modal value over 100 RUs). Mutating the genes corresponding to these two proteins causes the formation of short-chain O antigen chains and significantly reduces bacterial pathogenicity .

HY-D1056C1

Lipopolysaccharides, from S. enterica serotype enteritidis LPS, from Salmonella enterica (Serotype enteritidis)	Carbohydrates
Lipopolysaccharides, from S. enterica serotype enteritidis is a lipopolysaccharide endotoxin that causes gastrointestinal disease in humans and can be transmitted through contaminated eggs or foods based on eggs and poultry meat products. S. enterica serotype enteritidis is capable of producing high molecular weight LPS-O antigen chains, Lipopolysaccharides, from S. enterica serotype typhimurium (HY-D1056C3) did not. S. enterica serotype enteritidis is similar to other pathogenic Salmonella. Lipopolysaccharides, from S. enterica serotype enteritidis' O antigen is associated with phage attachment in the early stages of phage infection S. Enteritidis .

Lipopolysaccharides, from S. enterica serotype enteritidis

LPS, from Salmonella enterica (Serotype enteritidis)

Carbohydrates

Lipopolysaccharides, from S. enterica serotype enteritidis is a lipopolysaccharide endotoxin that causes gastrointestinal disease in humans and can be transmitted through contaminated eggs or foods based on eggs and poultry meat products. S. enterica serotype enteritidis is capable of producing high molecular weight LPS-O antigen chains, Lipopolysaccharides, from S. enterica serotype typhimurium (HY-D1056C3) did not. S. enterica serotype enteritidis is similar to other pathogenic Salmonella. Lipopolysaccharides, from S. enterica serotype enteritidis' O antigen is associated with phage attachment in the early stages of phage infection S. Enteritidis .

Cat. No.	Product Name	Target	Research Area

HY-119543

O-Succinyl-L-homoserine	Amino Acid Derivatives	Others
O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .

HY-P5734

Bactenecin 5	Bacterial	Infection
Bactenecin 5 is a bovine antibacterial peptide. Bactenecin 5 is active against Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. T, with MIC values of 12-25 μg/mL .

O-Succinyl-L-homoserine	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Amino Acid Derivatives
O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .

Catalpin	Structural Classification Iridoids Terpenoids Source classification Sorbus pohuashanensis (Hance) Hedl. Rosaceae Plants	Bacterial
Catalpin is an iridoid that can be isoalted from Catalpae Fructus.Catalpin shows mutagenic activity towards Salmonella typhimurium strain TA100 .

4-Decanol	Structural Classification Natural Products Capillipedium parviflorum (R. Br.) Stapf Gramineae Source classification Plants	Others
4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of $AFB_1$ and MNNG in Salmonella typhimurium TA100 .

2-Hydroxyemodin	Quinones other families Classification of Application Fields Anthraquinones Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Drug Metabolite
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system .

7-O-Methylaloeresin A	Structural Classification Monophenols Liliaceae Classification of Application Fields Simple Phenylpropanols Source classification Phenols Aloe vera (L.) Burm. f. Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Bacterial
7-O-Methylaloeresin A is 5-methylchromone glycoside isolated from Commiphora socotrana (Burseraceae). 7-O-Methylaloeresin A exhibits good activity against multiple agent resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mM, respectively. 7-O-Methylaloeresin A has antioxidant activities, gives IC50 values of 0.026 mM and 0.021 mM for DPPH and 2-deoxyribose degradation assay, respectively.

Aldgamycin E	Structural Classification Microorganisms Antibiotics Source classification	Antibiotic Bacterial
Aldgamycin E is a neutral macrolide antibiotic that can be derived from culture filtrates of Streptomyces lavendulae. Aldgamycin E has antibacterial activity .

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Salmonella typhimurium

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Natural
Products