Search Result
Results for "
UVB
" in MedChemExpress (MCE) Product Catalog:
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-109654
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Reactive Oxygen Species
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Metabolic Disease
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Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
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- HY-N0181A
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9β,10α-Ergosterol
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Endogenous Metabolite
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Metabolic Disease
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Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol (HY-N0181). Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities .
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- HY-N6641
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Keap1-Nrf2
PPAR
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Inflammation/Immunology
Cancer
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Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist .
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- HY-N12150
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MMP
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Others
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Isozedoarondiol can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb. Isozedoarondiol inhibits MMP-1 expression in UVB-treated human keratinocytes .
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- HY-W011889
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Others
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Others
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Actinoquinol is a UVB absorber that can be helpful for the human eye in the defence against photooxidative and other oxidative processes .
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- HY-116145
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Tyrosinase
NF-κB
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Inflammation/Immunology
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MHY884 is a tyrosinase inhibitor that suppresses UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress. MHY884 suppresses oxidative stress in the melanoma cells and attenuates UVB-induced oxidative stress, resulting in reduced NF-κB activity in irradiated mice. MHY884 is promising for research of UVB-induced skin damage .
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- HY-W419643
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Others
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Others
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Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .
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- HY-N6641R
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Keap1-Nrf2
PPAR
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Inflammation/Immunology
Cancer
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Monascin (Standard) is the analytical standard of Monascin. This product is intended for research and analytical applications. Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist .
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- HY-W020044S
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Ferroptosis
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Others
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DL-alpha-Tocopherol- 13C3 is the 13C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].
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- HY-W020044S1
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Ferroptosis
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Others
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DL-alpha-Tocopherol-d9 is the deuterium labeled DL-alpha-Tocopherol[1]. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[2].
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- HY-109655
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- HY-B0966
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Benzophenone-8; UV-24
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Biochemical Assay Reagents
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Others
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Dioxybenzone is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays.
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- HY-W419643R
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Others
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Others
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Drometrizole trisiloxane (Standard) is the analytical standard of Drometrizole trisiloxane. This product is intended for research and analytical applications. Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .
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- HY-B0897
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- HY-B1162
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Benzophenone-4
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Biochemical Assay Reagents
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Others
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Sulisobenzone is an ingredient in some sunscreens which protects the skin from damage by UVB and short-wave UVA ultraviolet light.
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- HY-B0929
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Octyl salicylate; 2-Ethylhexyl salicylate
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Biochemical Assay Reagents
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Others
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Octisalate (Octyl salicylate) is an organic compound with high lipophilicity, which is used in sunscreens and cosmetics that absorbs UVB rays .
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- HY-B0929R
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Octyl salicylate (Standard); 2-Ethylhexyl salicylate (Standard)
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Biochemical Assay Reagents
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Others
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Octisalate (Standard) is the analytical standard of Octisalate. This product is intended for research and analytical applications. Octisalate is an organic compound used in sunscreens and cosmetics that absorbs UVB rays.
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- HY-N2406
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3,4-Dihydroxy-benzenepropanoic acid
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p38 MAPK
Endogenous Metabolite
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Inflammation/Immunology
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Dihydrocaffeic acid is a microbial metabolite of flavonoids, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity .
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- HY-W020044
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DL-α-Tocopherol
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Ferroptosis
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Others
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DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
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- HY-W749966
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Isotope-Labeled Compounds
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Metabolic Disease
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Octocrylene-d10 is the deuterium labeled Octocrylene. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths .
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- HY-B0966R
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Benzophenone-8 (Standard); UV-24 (Standard)
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Biochemical Assay Reagents
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Others
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Dioxybenzone (Standard) is the analytical standard of Dioxybenzone. This product is intended for research and analytical applications. Dioxybenzone is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation.
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- HY-167740
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GroPIns (lysine)
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Others
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Inflammation/Immunology
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Glycerophosphoinositol (GroPIns) lysine is a phospholipid metabolite that possesses anti-dandruff, anti-inflammatory, and anti-aging activities; it significantly suppresses UVB-induced PGE secretion in NHEK keratinocytes.
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- HY-109655R
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Biochemical Assay Reagents
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Others
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Ethylhexyl triazone (Standard) is the analytical standard of Ethylhexyl triazone. This product is intended for research and analytical applications. Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.
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- HY-137989
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Voriconazole oxynitride
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Fungal
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Infection
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Voriconazole N-oxide (Voriconazole oxynitride) is a potent antifungal agent. Voriconazole N-oxide has phototoxicity and photocarcinogenicity. Voriconazole N-oxide does not sensitize keratinocytes to ultraviolet B (UVB) .
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- HY-B0897R
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Biochemical Assay Reagents
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Others
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Bisoctrizole (Standard) is the analytical standard of Bisoctrizole. This product is intended for research and analytical applications. Bisoctrizole is a broad-spectrum UV absorber that absorbs UVB and UVA rays while reflecting and scattering UV rays.
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- HY-N5124
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Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside
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Others
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Infection
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Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid isolated from barley with antioxidant activity. In barley, phenylpropanoids have been described as having protective properties against excess UV-B radiation and have been linked to resistance to pathogens .
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- HY-133079
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tetra-isopalmitoyl Ascorbic acid; IPAA; Tetrahexyldecyl Ascorbate
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Prostaglandin Receptor
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Endocrinology
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Ascorbyl tetraisopalmitate is a lipophilic derivative of vitamin C (L-ascorbic acid). It protects against UVB-, hydrogen peroxide-, or tert-butyl hydroperoxide-induced decreases in cell viability in HaCaT keratinocytes when used at a concentration of 100 μM.1 Ascorbyl tetraisopalmitate (20 μM) decreases IL-1α and prostaglandin E2 production in unstimulated and UVB-stimulated HaCaT keratinocytes. Topical application of ascorbyl tetraisopalmitate (1%) increases viable epidermis thickness, stratum corneum water content, and skin smoothness and decreases skin roughness in hairless mice.2 Formulations containing ascorbyl tetraisopalmitate have been used in cosmetic products as skin-lightening agents.
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- HY-W020044R
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Ferroptosis
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Others
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DL-alpha-Tocopherol (Standard) is the analytical standard of DL-alpha-Tocopherol. This product is intended for research and analytical applications. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
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- HY-109654R
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Reactive Oxygen Species
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Metabolic Disease
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Ensulizole (Standard) is the analytical standard of Ensulizole. This product is intended for research and analytical applications. Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
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- HY-N3612
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(+)-Communic acid
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Bacterial
Akt
MMP
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Infection
Inflammation/Immunology
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Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging .
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- HY-N0244
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Apoptosis
Necroptosis
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Cancer
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Theaflavin-3'-gallate is a monomer of theaflavins found in black tea, which has anti-UVB damage activity and inhibits cell apoptosis and necroptosis. Theaflavin-3'-gallate acts as a pro-oxidant and induces oxidative stress in cancer cells, inhibiting xanthine oxidase (OX), with an IC50 of 7.6 μM .
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- HY-B1234A
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(E)-Octyl methoxycinnamate
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Estrogen Receptor/ERR
Androgen Receptor
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Endocrinology
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(E)-Octinoxate is the isomer of Octinoxate (HY-B1234). Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
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- HY-A0087R
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Biochemical Assay Reagents
PPAR
Estrogen Receptor/ERR
Cytochrome P450
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Others
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Octocrylene (Standard) is the analytical standard of Octocrylene. This product is intended for research and analytical applications. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation .
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- HY-N2007
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3,4-Dimethoxybenzoic acid
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COX
Reactive Oxygen Species
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Cardiovascular Disease
Inflammation/Immunology
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Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .
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- HY-B1234R
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Androgen Receptor
Estrogen Receptor/ERR
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Others
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Octinoxate (Standard) is the analytical standard of Octinoxate. This product is intended for research and analytical applications. Octinoxate (Octyl methoxycinnamate) is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
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- HY-A0087
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Biochemical Assay Reagents
PPAR
Estrogen Receptor/ERR
Cytochrome P450
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Others
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Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
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- HY-14933
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ERB-041
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Estrogen Receptor/ERR
Wnt
Apoptosis
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Cancer
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Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis .
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- HY-N2007R
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COX
Reactive Oxygen Species
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Cardiovascular Disease
Inflammation/Immunology
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Veratric acid (Standard) is the analytical standard of Veratric acid. This product is intended for research and analytical applications. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .
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- HY-N2007S
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3,4-Dimethoxybenzoic acid-d6
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Isotope-Labeled Compounds
COX
Reactive Oxygen Species
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Cardiovascular Disease
Inflammation/Immunology
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Veratric acid-d6 is deuterium labeled Veratric acid. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant[1] and anti-inflammatory activities[3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling[2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation[3].
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- HY-W743654
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Others
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Cancer
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Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
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- HY-P0064
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Palmitoyl Tetrapeptide-7
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Interleukin Related
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Inflammation/Immunology
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Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .
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- HY-W743654R
-
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Others
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Cancer
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Capsorubin (Standard) is the analytical standard of Capsorubin. This product is intended for research and analytical applications. Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P0064
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Palmitoyl Tetrapeptide-7
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Interleukin Related
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Inflammation/Immunology
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Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .
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- HY-A0299
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Tripeptide 29
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Peptides
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Others
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HGly-Pro-Hyp-OH (Tripeptide 29) is an orally active bioactive peptide against UVB-induced skin aging and has been reported used as a cosmetic ingredient [1]
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W020044S
-
|
DL-alpha-Tocopherol- 13C3 is the 13C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].
|
-
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- HY-W020044S1
-
|
DL-alpha-Tocopherol-d9 is the deuterium labeled DL-alpha-Tocopherol[1]. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[2].
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- HY-W749966
-
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Octocrylene-d10 is the deuterium labeled Octocrylene. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths .
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- HY-N2007S
-
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Veratric acid-d6 is deuterium labeled Veratric acid. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant[1] and anti-inflammatory activities[3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling[2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation[3].
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