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Results for "

UVB

" in MedChemExpress (MCE) Product Catalog:

42

Inhibitors & Agonists

2

Peptides

13

Natural
Products

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-109654
    Ensulizole

    		Reactive Oxygen Species Metabolic Disease
    Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
    Ensulizole
  • HY-N0181A
    Lumisterol

    9β,10α-Ergosterol

    		 Endogenous Metabolite Metabolic Disease
    Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol (HY-N0181). Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities .
    Lumisterol
  • HY-N6641
    Monascin

    		Keap1-Nrf2 PPAR Inflammation/Immunology Cancer
    Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist .
    Monascin
  • HY-N12150
    Isozedoarondiol

    		MMP Others
    Isozedoarondiol can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb. Isozedoarondiol inhibits MMP-1 expression in UVB-treated human keratinocytes .
    Isozedoarondiol
  • HY-W011889
    Actinoquinol

    		Others Others
    Actinoquinol is a UVB absorber that can be helpful for the human eye in the defence against photooxidative and other oxidative processes .
    Actinoquinol
  • HY-116145
    MHY884

    		Tyrosinase NF-κB Inflammation/Immunology
    MHY884 is a tyrosinase inhibitor that suppresses UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress. MHY884 suppresses oxidative stress in the melanoma cells and attenuates UVB-induced oxidative stress, resulting in reduced NF-κB activity in irradiated mice. MHY884 is promising for research of UVB-induced skin damage .
    MHY884
  • HY-W419643
    Drometrizole trisiloxane

    		Others Others
    Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .
    Drometrizole trisiloxane
  • HY-N6641R
    Monascin (Standard)

    		Keap1-Nrf2 PPAR Inflammation/Immunology Cancer
    Monascin (Standard) is the analytical standard of Monascin. This product is intended for research and analytical applications. Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist .
    Monascin (Standard)
  • HY-W020044S
    DL-alpha-Tocopherol-13C3

    		Ferroptosis Others
    DL-alpha-Tocopherol- 13C3 is the 13C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].
    DL-alpha-Tocopherol-13C3
  • HY-W020044S1
    DL-alpha-Tocopherol-d9

    		Ferroptosis Others
    DL-alpha-Tocopherol-d9 is the deuterium labeled DL-alpha-Tocopherol[1]. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[2].
    DL-alpha-Tocopherol-d9
  • HY-109655
    Ethylhexyl triazone

    Octyl triazone

    		 Biochemical Assay Reagents Others
    Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.
    Ethylhexyl triazone
  • HY-B0966
    Dioxybenzone

    Benzophenone-8; UV-24

    		 Biochemical Assay Reagents Others
    Dioxybenzone is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays.
    Dioxybenzone
  • HY-W419643R
    Drometrizole trisiloxane (Standard)

    		Others Others
    Drometrizole trisiloxane (Standard) is the analytical standard of Drometrizole trisiloxane. This product is intended for research and analytical applications. Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .
    Drometrizole trisiloxane (Standard)
  • HY-B0897
    Bisoctrizole
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    Bisoctrizole is a broad-spectrum UV absorber that absorbs UVB and UVA rays while reflecting and scattering UV rays.
    Bisoctrizole
  • HY-B1162
    Sulisobenzone

    Benzophenone-4

    		 Biochemical Assay Reagents Others
    Sulisobenzone is an ingredient in some sunscreens which protects the skin from damage by UVB and short-wave UVA ultraviolet light.
    Sulisobenzone
  • HY-B0929
    Octisalate

    Octyl salicylate; 2-Ethylhexyl salicylate

    		 Biochemical Assay Reagents Others
    Octisalate (Octyl salicylate) is an organic compound with high lipophilicity, which is used in sunscreens and cosmetics that absorbs UVB rays .
    Octisalate
  • HY-B0929R
    Octisalate (Standard)

    Octyl salicylate (Standard); 2-Ethylhexyl salicylate (Standard)

    		 Biochemical Assay Reagents Others
    Octisalate (Standard) is the analytical standard of Octisalate. This product is intended for research and analytical applications. Octisalate is an organic compound used in sunscreens and cosmetics that absorbs UVB rays.
    Octisalate (Standard)
  • HY-N2406
    Dihydrocaffeic acid
    1 Publications Verification

    3,4-Dihydroxy-benzenepropanoic acid

    		 p38 MAPK Endogenous Metabolite Inflammation/Immunology
    Dihydrocaffeic acid is a microbial metabolite of flavonoids, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity .
    Dihydrocaffeic acid
  • HY-W020044
    DL-alpha-Tocopherol
    3 Publications Verification

    DL-α-Tocopherol

    		 Ferroptosis Others
    DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
    DL-alpha-Tocopherol
  • HY-W749966
    Octocrylene-d10

    		Isotope-Labeled Compounds Metabolic Disease
    Octocrylene-d10 is the deuterium labeled Octocrylene. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths .
    Octocrylene-d10
  • HY-B0966R
    Dioxybenzone (Standard)

    Benzophenone-8 (Standard); UV-24 (Standard)

    		 Biochemical Assay Reagents Others
    Dioxybenzone (Standard) is the analytical standard of Dioxybenzone. This product is intended for research and analytical applications. Dioxybenzone is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation.
    Dioxybenzone (Standard)
  • HY-167740
    Glycerophosphoinositol (lysine)

    GroPIns (lysine)

    		 Others Inflammation/Immunology
    Glycerophosphoinositol (GroPIns) lysine is a phospholipid metabolite that possesses anti-dandruff, anti-inflammatory, and anti-aging activities; it significantly suppresses UVB-induced PGE secretion in NHEK keratinocytes.
    Glycerophosphoinositol (lysine)
  • HY-109655R
    Ethylhexyl triazone (Standard)

    		Biochemical Assay Reagents Others
    Ethylhexyl triazone (Standard) is the analytical standard of Ethylhexyl triazone. This product is intended for research and analytical applications. Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.
    Ethylhexyl triazone (Standard)
  • HY-137989
    Voriconazole N-oxide

    Voriconazole oxynitride

    		 Fungal Infection
    Voriconazole N-oxide (Voriconazole oxynitride) is a potent antifungal agent. Voriconazole N-oxide has phototoxicity and photocarcinogenicity. Voriconazole N-oxide does not sensitize keratinocytes to ultraviolet B (UVB) .
    Voriconazole N-oxide
  • HY-B0897R
    Bisoctrizole (Standard)

    		Biochemical Assay Reagents Others
    Bisoctrizole (Standard) is the analytical standard of Bisoctrizole. This product is intended for research and analytical applications. Bisoctrizole is a broad-spectrum UV absorber that absorbs UVB and UVA rays while reflecting and scattering UV rays.
    Bisoctrizole (Standard)
  • HY-N5124
    Meloside A
    1 Publications Verification

    Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside

    		 Others Infection
    Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid isolated from barley with antioxidant activity. In barley, phenylpropanoids have been described as having protective properties against excess UV-B radiation and have been linked to resistance to pathogens .
    Meloside A
  • HY-133079
    Ascorbyl tetra-2-hexyldecanoate

    tetra-isopalmitoyl Ascorbic acid; IPAA; Tetrahexyldecyl Ascorbate

    		 Prostaglandin Receptor Endocrinology
    Ascorbyl tetraisopalmitate is a lipophilic derivative of vitamin C (L-ascorbic acid). It protects against UVB-, hydrogen peroxide-, or tert-butyl hydroperoxide-induced decreases in cell viability in HaCaT keratinocytes when used at a concentration of 100 μM.1 Ascorbyl tetraisopalmitate (20 μM) decreases IL-1α and prostaglandin E2 production in unstimulated and UVB-stimulated HaCaT keratinocytes. Topical application of ascorbyl tetraisopalmitate (1%) increases viable epidermis thickness, stratum corneum water content, and skin smoothness and decreases skin roughness in hairless mice.2 Formulations containing ascorbyl tetraisopalmitate have been used in cosmetic products as skin-lightening agents.
    Ascorbyl tetra-2-hexyldecanoate
  • HY-W020044R
    DL-alpha-Tocopherol (Standard)
    3 Publications Verification

    		 Ferroptosis Others
    DL-alpha-Tocopherol (Standard) is the analytical standard of DL-alpha-Tocopherol. This product is intended for research and analytical applications. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
    DL-alpha-Tocopherol (Standard)
  • HY-109654R
    Ensulizole (Standard)

    		Reactive Oxygen Species Metabolic Disease
    Ensulizole (Standard) is the analytical standard of Ensulizole. This product is intended for research and analytical applications. Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
    Ensulizole (Standard)
  • HY-N3612
    Communic acid

    (+)-Communic acid

    		 Bacterial Akt MMP Infection Inflammation/Immunology
    Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging .
    Communic acid
  • HY-N0244
    Theaflavin-3'-gallate
    1 Publications Verification

    		 Apoptosis Necroptosis Cancer
    Theaflavin-3'-gallate is a monomer of theaflavins found in black tea, which has anti-UVB damage activity and inhibits cell apoptosis and necroptosis. Theaflavin-3'-gallate acts as a pro-oxidant and induces oxidative stress in cancer cells, inhibiting xanthine oxidase (OX), with an IC50 of 7.6 μM .
    Theaflavin-3'-gallate
  • HY-B1234A
    (E)-Octinoxate

    (E)-Octyl methoxycinnamate

    		 Estrogen Receptor/ERR Androgen Receptor Endocrinology
    (E)-Octinoxate is the isomer of Octinoxate (HY-B1234). Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
    (E)-Octinoxate
  • HY-A0087R
    Octocrylene (Standard)

    		Biochemical Assay Reagents PPAR Estrogen Receptor/ERR Cytochrome P450 Others
    Octocrylene (Standard) is the analytical standard of Octocrylene. This product is intended for research and analytical applications. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation .
    Octocrylene (Standard)
  • HY-N2007
    Veratric acid

    3,4-Dimethoxybenzoic acid

    		 COX Reactive Oxygen Species Cardiovascular Disease Inflammation/Immunology
    Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .
    Veratric acid
  • HY-B1234R
    Octinoxate (Standard)

    		Androgen Receptor Estrogen Receptor/ERR Others
    Octinoxate (Standard) is the analytical standard of Octinoxate. This product is intended for research and analytical applications. Octinoxate (Octyl methoxycinnamate) is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
    Octinoxate (Standard)
  • HY-A0087
    Octocrylene
    2 Publications Verification

    		 Biochemical Assay Reagents PPAR Estrogen Receptor/ERR Cytochrome P450 Others
    Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
    Octocrylene
  • HY-14933
    Prinaberel
    3 Publications Verification

    ERB-041

    		 Estrogen Receptor/ERR Wnt Apoptosis Cancer
    Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis .
    Prinaberel
  • HY-N2007R
    Veratric acid (Standard)

    		COX Reactive Oxygen Species Cardiovascular Disease Inflammation/Immunology
    Veratric acid (Standard) is the analytical standard of Veratric acid. This product is intended for research and analytical applications. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .
    Veratric acid (Standard)
  • HY-N2007S
    Veratric acid-d6

    3,4-Dimethoxybenzoic acid-d6

    		 Isotope-Labeled Compounds COX Reactive Oxygen Species Cardiovascular Disease Inflammation/Immunology
    Veratric acid-d6 is deuterium labeled Veratric acid. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant[1] and anti-inflammatory activities[3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling[2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation[3].
    Veratric acid-d6
  • HY-W743654
    Capsorubin

    		Others Cancer
    Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
    Capsorubin
  • HY-P0064
    Palmitoyl Tetrapeptide-3

    Palmitoyl Tetrapeptide-7

    		 Interleukin Related Inflammation/Immunology
    Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .
    Palmitoyl Tetrapeptide-3
  • HY-W743654R
    Capsorubin (Standard)

    		Others Cancer
    Capsorubin (Standard) is the analytical standard of Capsorubin. This product is intended for research and analytical applications. Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
    Capsorubin (Standard)

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