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compulsive

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Adrenergic Receptor (2) Apoptosis (2) EAAT (1) Isotope-Labeled Compounds (2) Opioid Receptor (3) P2X Receptor (2) Serotonin Transporter (8) Trace Amine-associated Receptor (TAAR) (1)
By Research Areas:	Cancer (3) Neurological Disease (14)

Inhibitors & Agonists

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0457

Clomipramine hydrochloride 2 Publications Verification Chlorimipramine hydrochloride; G-34586 hydrochloride; NSC-169865 hydrochloride	Serotonin Transporter	Neurological Disease
Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC₅₀ value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .

HY-B0457A

Clomipramine 2 Publications Verification Chlorimipramine; G-34586; NSC-169865	Serotonin Transporter	Neurological Disease
Clomipramine (Chlorimipramine) is a potent 5-HT reuptake blocker with the IC₅₀ value of 1.5 nM. Clomipramine is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .

HY-118858

UCPH-102	EAAT	Neurological Disease Cancer
UCPH-102 is a highly selective EAAT1 inhibitor with an IC₅₀ of 0.43 µM. UCPH-102 exhibits a specific anti-proliferative effect on T-ALL cells. UCPH-102 also shows good blood-brain permeability, which can be used in studies of amyotrophic lateral sclerosis, Alzheimer’s disease, chronic pain and obsessive compulsive disorder .

HY-115066

GSK1521498 free base	Opioid Receptor	Neurological Disease
GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base has the potential for disorders of compulsive consumption of food, alcohol, and agents .

HY-B0457AR

Clomipramine (Standard)	Serotonin Transporter	Neurological Disease
Clomipramine (Standard) is the analytical standard of Clomipramine. This product is intended for research and analytical applications. Clomipramine (Chlorimipramine) is a potent 5-HT reuptake blocker with the IC₅₀ value of 1.5 nM. Clomipramine is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .

HY-B0457R

Clomipramine (hydrochloride) (Standard)	Serotonin Transporter	Neurological Disease
Clomipramine (hydrochloride) (Standard) is the analytical standard of Clomipramine (hydrochloride). This product is intended for research and analytical applications. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC₅₀ value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .

HY-19902

GSK1521498	Opioid Receptor	Neurological Disease
GSK1521498 is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 has the potential for disorders of compulsive consumption of food, alcohol, and agents .

HY-115066A

GSK1521498 free base (hydrochloride)	Opioid Receptor	Neurological Disease
GSK1521498 free base (hydrochloride) is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base (hydrochloride) is being used for the treatment of disorders of compulsive consumption of food, alcohol, and agents .

HY-B0457S1

Clomipramine-d6 hydrochloride Chlorimipramine-d₆ (hydrochloride); G-34586-d₆ (hydrochloride); NSC-169865-d₆ (hydrochloride)	Serotonin Transporter	Neurological Disease
Clomipramine-d₆ (hydrochloride) is the deuterium labeled Clomipramine hydrochloride. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

HY-B0457S2

Clomipramine-13C,d3 hydrochloride Chlorimipramine-¹³C,d₃ hydrochloride; G-34586-¹³C,d₃ hydrochloride; NSC-169865-¹³C,d₃ hydrochloride	Isotope-Labeled Compounds Serotonin Transporter	Neurological Disease
Clomipramine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Clomipramine (hydrochloride). Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

HY-122272

Paroxetine Maximum Cited Publications 8 Publications Verification BRL29060	Serotonin Transporter Adrenergic Receptor P2X Receptor Apoptosis	Neurological Disease Cancer
Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches .

HY-12700

RO5256390 2 Publications Verification	Trace Amine-associated Receptor (TAAR)	Neurological Disease
RO5256390 is an orally effective trace amine associated receptor 1 (TAAR1) agonist. RO5256390 exhibits pro-cognitive and antidepressant-like properties in rodent and primate models, showing similar brain activation patterns to Olanzapine (HY-14541). RO5256390 blocks compulsive overeating behavior in rats. RO5256390 can inhibit ATP (HY-B2176)-induced TNF secretion in mouse bone marrow-derived macrophages .

HY-101300

Cirazoline hydrochloride LD 3098 hydrochloride	Adenosine Receptor	Neurological Disease
Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full?α1A-adrenergic receptor (α1A-AR) agonist (K_i=120 nM) and only a partial agonist at α1B-AR (K_i= 960 nM) and α1D-AR (K_i=660 nM) .

HY-122272S

Paroxetine-d4 BRL29060-d₄	Isotope-Labeled Compounds Serotonin Transporter Adrenergic Receptor Apoptosis P2X Receptor	Neurological Disease Cancer
Paroxetine-d₄ (BRL29060-d₄) is deuterium labeled Paroxetine. Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches .

Cat. No.	Product Name	Chemical Structure

HY-B0457S1

Clomipramine-d6 hydrochloride
Clomipramine-d₆ (hydrochloride) is the deuterium labeled Clomipramine hydrochloride. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

HY-B0457S2

Clomipramine-13C,d3 hydrochloride
Clomipramine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Clomipramine (hydrochloride). Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

HY-122272S

Paroxetine-d4
Paroxetine-d₄ (BRL29060-d₄) is deuterium labeled Paroxetine. Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches .

Paroxetine-d4

Paroxetine-d₄ (BRL29060-d₄) is deuterium labeled Paroxetine. Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches .

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