Search Result

Results for "

consumption

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (4) Adrenergic Receptor (2) Akt (1) Aldehyde Dehydrogenase (ALDH) (3) AMPK (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (2) Apoptosis (5) Bacterial (4) Cannabinoid Receptor (1) Cytochrome P450 (1) Drug Metabolite (1) Endogenous Metabolite (11) Fatty Acid Synthase (FASN) (1) Ferroptosis (1) FGFR (1) Fungal (4) GABA Receptor (1) Interleukin Related (2) Isotope-Labeled Compounds (5) Lipoxygenase (1) Mitochondrial Metabolism (7) Na+/K+ ATPase (1) nAChR (3) NADPH Oxidase (1) NAMPT (1) Neuropeptide Y Receptor (1) Opioid Receptor (3) Orexin Receptor (OX Receptor) (2) PDGFR (1) PDK-1 (2) Phosphatase (6) Phosphodiesterase (PDE) (2) PKC (1) PPAR (2) Reactive Oxygen Species (4) Reverse Transcriptase (2) Succinate Dehydrogenase (2) VEGFR (1) α-synuclein (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (5) Endocrinology (3) Infection (6) Inflammation/Immunology (5) Metabolic Disease (21) Neurological Disease (21)

By Targets:

5-HT Receptor (4)

Adrenergic Receptor (2)

Akt (1)

Aldehyde Dehydrogenase (ALDH) (3)

AMPK (1)

Angiotensin-converting Enzyme (ACE) (1)

Antibiotic (2)

Apoptosis (5)

Bacterial (4)

Cannabinoid Receptor (1)

Cytochrome P450 (1)

Drug Metabolite (1)

Endogenous Metabolite (11)

Fatty Acid Synthase (FASN) (1)

Ferroptosis (1)

FGFR (1)

Fungal (4)

GABA Receptor (1)

Interleukin Related (2)

Isotope-Labeled Compounds (5)

Lipoxygenase (1)

Mitochondrial Metabolism (7)

Na+/K+ ATPase (1)

nAChR (3)

NADPH Oxidase (1)

NAMPT (1)

Neuropeptide Y Receptor (1)

Opioid Receptor (3)

Orexin Receptor (OX Receptor) (2)

PDGFR (1)

PDK-1 (2)

Phosphatase (6)

Phosphodiesterase (PDE) (2)

PKC (1)

PPAR (2)

Reactive Oxygen Species (4)

Reverse Transcriptase (2)

Succinate Dehydrogenase (2)

VEGFR (1)

α-synuclein (1)

By Research Areas:

Cancer (13)

Cardiovascular Disease (5)

Endocrinology (3)

Infection (6)

Inflammation/Immunology (5)

Metabolic Disease (21)

Neurological Disease (21)

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16688A

RU 24969 succinate 1 Publications Verification	5-HT Receptor	Neurological Disease
RU 24969 succinate is a 5-HT receptor agonist with K_i values of 0.38 and 2.5 nM for 5-HT_1B and 5-HT_1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease .

HY-155363

AMPK activator 13	AMPK	Metabolic Disease
AMPK activator 13 is a potent activator of AMPK. AMPK activator 13 inhibits mitotic clonal expansion of 3T3-L1 cells by activating AMPK pathway and enhances cell mitochondrial oxygen consumption rate. AMPK activator 13 can be used in study obesity .

HY-138879B

CP-601932 (1S,5R)-CP-601927	nAChR	Neurological Disease
CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (K_i=21 nM; EC₅₀=~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (K_i=21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS .

HY-18686

AS1949490 1 Publications Verification	Phosphatase Akt	Metabolic Disease
AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC₅₀ values of 0.34, 0.62, 13, >50, >50, and >50 µM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes .

HY-W017007

3-Methyl-L-histidine	Endogenous Metabolite	Metabolic Disease
3-Methyl-L-histidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.

HY-146240

ALDH1A1-IN-3	Aldehyde Dehydrogenase (ALDH)	Metabolic Disease
ALDH1A1-IN-3 (compound 57) is an excellent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor with an IC₅₀ value of 0.379 μM. ALDH1A1-IN-3 can effectively improve glucose consumption in HepG2 cells. ALDH1A1-IN-3 can be used for researching glucose metabolism improvement .

HY-146977

LDHA/PDKs-IN-1	PDK-1	Cancer
LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC₅₀s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC₅₀ of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases .

HY-146978

LDHA/PDKs-IN-2	PDK-1	Cancer
LDHA/PDKs-IN-2 (compound 20k) is a potent and dual inhibitor of PDKs and LDHA with IC₅₀s of 1.6 and 0.7 μM, respectively. LDHA/PDKs-IN-2 reduces A549 cell proliferation with an EC₅₀ of 15.7 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-2 has the potential for the research of cancer diseases .

HY-W017007S

3-Methyl-L-histidine-d3	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
3-Methyl-L-histidine-d₃ is the deuterium labeled 3-Methyl-L-histidine. 3-Methyl-L-histidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.

HY-114976

S-Allylmercapturic acid	Drug Metabolite	Metabolic Disease
S-Allylmercapturic acid is a biomarker of food intake (BFIs) for garlic consumption .

HY-W041019

5-Hydroxytryptophol	Endogenous Metabolite	Others
5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.

HY-113340

2-Furoylglycine	Endogenous Metabolite	Others
2-Furoylglycine, a urinary metabolite in human, is a putative biomarker for coffee consumption .

HY-33893

Indole-3-methanamine	Endogenous Metabolite	Metabolic Disease
Indole-3-methanamine is a potential biomarker for the consumption of these foods such as barley, cereals, and cereal product .

HY-W016509

epi-Inositol	Endogenous Metabolite	Others
epi-Inositol is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Ethanol Consumption .

HY-W015560

3,5-Dihydroxybenzoic acid	Endogenous Metabolite	Metabolic Disease
3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses.

HY-17030

Acamprosate calcium Calcium N-acetylhomotaurinate	GABA Receptor	Neurological Disease
Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction.

HY-126752

Ophthalmic acid	Reactive Oxygen Species	Inflammation/Immunology
Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction .

HY-153993

Pyrocatechol sulfate	Endogenous Metabolite	Others
Pyrocatechol sulfate, a phenolic metabolite present in human plasma, is associated with the consumption of specific foods such as berries and the condition of gut microbiota. It serves as a potential urinary biomarker for kidney function, dialytic clearance, whole grain consumption, and regular coffee intake. Additionally, Pyrocatechol sulfate, along with other phenolic sulfates, plays a role in modulating various biological functions, including those related to brain health and the rhythmic beating of cardiomyocytes.

HY-N0018

Daidzin 5 Publications Verification Daidzoside; NPI-031D; Daidzein 7-O-glucoside	Mitochondrial Metabolism Reverse Transcriptase Aldehyde Dehydrogenase (ALDH)	Cardiovascular Disease Others Cancer
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .

HY-W007426

N-Methylbenzylamine	Others	Others
N-methylbenzylamine is a member of phenylmethylamines. N-methylbenzylamine can be found in carrot, which makes N-methylbenzylamine a potential biomarker for the consumption of these food products .

HY-W267444

Pentyl 4-hydroxybenzoate Amylparaben	Bacterial	Infection
Pentyl 4-hydroxybenzoate (Amylparaben) is a type of paraben compound commonly used as a preservative, it has antibacterial properties and is related to the inhibition of induced oxygen consumption .

HY-19902

GSK1521498	Opioid Receptor	Neurological Disease
GSK1521498 is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 has the potential for disorders of compulsive consumption of food, alcohol, and agents .

HY-W041019S

5-Hydroxytryptophol-d4	Endogenous Metabolite	Others
5-Hydroxytryptophol-d₄ is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.

HY-123856

MY10	Phosphatase	Neurological Disease
MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor. MY10 attenuates binge-like ethanol consumption and ethanol reward .

HY-P2740

Alcohol dehydrogenase, Saccharomyces cerevisiae EC 1.1.1.1	Endogenous Metabolite	Metabolic Disease
Alcohol dehydrogenase, Saccharomyces cerevisiae is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol .

HY-115066

GSK1521498 free base	Opioid Receptor	Neurological Disease
GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base has the potential for disorders of compulsive consumption of food, alcohol, and agents .

HY-158051

CIDD-0072424	PKC	Neurological Disease
CIDD-0072424 selectively inhibits Protein Kinase C-epsilon (PKCε) (K_i=54 nM). CIDD-0072424 reduces ethanol consumption and preference in a dose-dependent manner .

HY-15475

UK-5099 30+ Cited Publications PF-1005023	Mitochondrial Metabolism	Cancer
UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 (PF-1005023) inhibits pyruvate-dependent O₂ consumption with an IC₅₀ of 50 nM.

HY-115066A

GSK1521498 free base (hydrochloride)	Opioid Receptor	Neurological Disease
GSK1521498 free base (hydrochloride) is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base (hydrochloride) is being used for the treatment of disorders of compulsive consumption of food, alcohol, and agents .

HY-106844

EMD 53998	Phosphodiesterase (PDE)	Cardiovascular Disease
EMD 53998 is a cardiotonic agent that increases myocardial contractility as an inhibitor for phosphodiesterase III (PDE III) and a calcium sensitizer. EMD 53998 increases myocardial contractility, reduces energy consumption and the risk of inducing arrhythmias .

HY-N12169

Janthitrem A 11,12-Epoxyjanthitrem B	Others	Neurological Disease
Janthitrem A (11,12-Epoxyjanthitrem B) is a natural product that can be isolated from Penicillium janthinellum. Janthitrem A induces tremors in mice and reduces weight gain and food consumption of porina (Wiseana cervinata) larvae .

HY-N7176

Kaempferol 3-O-β-D-glucuronide 2 Publications Verification Kaempferol-3-glucuronide; Kaempferol-3-O-glucuronide	Interleukin Related	Metabolic Disease Inflammation/Immunology Cancer
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism .

HY-122964

URB447	Cannabinoid Receptor	Metabolic Disease
URB447 is a peripherally restricted CB₁ cannabinoid antagonist (IC₅₀: 313 nM and 41 nM for rat CB1 and human CB2 receptor respectively ). URB447 lowers food intake and body-weight gain in mice without entering the brain or antagonizing central CB₁-dependent responses. URB447 can be used for research of obesity .

HY-124778

SW106065	Apoptosis	Cancer
SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). SW106065 inhibits ATP consumption of sMPNST and other models of MPNST with an EC₅₀ of 1 µM. SW106065 can be used for MPNST research .

HY-N0018R

Daidzin (Standard)	Mitochondrial Metabolism Reverse Transcriptase Aldehyde Dehydrogenase (ALDH)	Others
Daidzin (Standard) is the analytical standard of Daidzin. This product is intended for research and analytical applications. Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .

HY-131901

Phenylarsine oxide Oxophenylarsine; PhAsO; Arsenosobenzene	Phosphatase	Others
Phenylarsine oxide (PAO), an inhibitor of endocytosis, inhibits PTPε with an IC₅₀ of 18 μM. Phenylarsine oxide (PAO) inhibits oxygen consumption and decreases cellular ATP content overlap with those used to inhibit protein internalization .

HY-W017092

1,2,3-Trimethoxybenzene	Others	Others
1,2,3-Trimethoxybenzene is a member of the class of compounds known as anisoles. 1,2,3-Trimethoxybenzene can be found in tea, which makes 1,2,3-trimethoxybenzene a potential biomarker for the consumption of this food product.

HY-N2953

Borapetoside E	Fatty Acid Synthase (FASN)	Metabolic Disease
Borapetoside E can be isolated from T. crispa. Borapetoside E improves hyperglycemia, insulin resistance, hepatic steatosis, hyperlipidemia, and oxygen consumption in obese mice. Borapetoside E also inhibits SREBPs expression in the liver and adipose tissue .

HY-170404

KF-52	Phosphatase	Metabolic Disease
KF-52 is a phosphofructokinase-1 (PFK1) inhibitor, with an IC₅₀ of 2.1 μM. KF-52 significantly increases the OCR/ECAR (OCR: oxygen consumption rate; ECAR: extracellular acidification rate) ratio .

HY-W007426S

N-Methylbenzylamine-d3	Isotope-Labeled Compounds	Others
N-Methylbenzylamine-d₃ is the deuterium labeled N-Methylbenzylamine[1]. N-methylbenzylamine is a member of phenylmethylamines. N-methylbenzylamine can be found in carrot, which makes N-methylbenzylamine a potential biomarker for the consumption of these food products[2].

HY-W015560R

3,5-Dihydroxybenzoic acid (Standard)	Endogenous Metabolite	Metabolic Disease
3,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 3,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses.

HY-18950

GSK2795039 Maximum Cited Publications 58 Publications Verification	NADPH Oxidase Reactive Oxygen Species Apoptosis	Cancer
GSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC₅₀ of 6 in different cell-free assays. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption . GSK2795039 reduces apoptosis .

HY-135057

Lauroylamide propylbetaine Lauramidopropyl betaine	Others	Others
Lauroylamide propylbetaine (Lauramidopropyl betaine) is an ampholytic surfactant for cosmetic and hair compositions to enhance viscosity and has good biodegradability. Lauroylamide propylbetaine promotes CH4 hydrate formation by reducing the induction time and increasing the CH4 consumption rate for hydrate growth .

HY-W014118S

α-Hexylcinnamaldehyde-d5	Isotope-Labeled Compounds	Cancer
α-Hexylcinnamaldehyde-d₅ is deuterated labeled Diacetoxyscirpenol (HY-N6692). Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals .

HY-B2011

Flutolanil	Fungal Mitochondrial Metabolism Succinate Dehydrogenase	Infection
Flutolanil is a broad-spectrum fungicide. Flutolanil inhibits mycelial oxygen consumption and succinate dehydrogenase in mitochondria Complex II. Flutolanil causes endocrine disruption and reproductive disorders in zebrafish after long-term exposure. Flutolanil can be used to control the fungal pathogens induced plant disease .

HY-N2086S

Ethyl palmitate-d31 Ethyl hexadecanoate-d₃₁	Isotope-Labeled Compounds	Others
Ethyl palmitate-d₃₁ is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent[1].

HY-N2086R

Ethyl palmitate (Standard)	Others	Others
Ethyl palmitate (Standard) is the analytical standard of Ethyl palmitate. This product is intended for research and analytical applications. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .

HY-B0655

Zofenopril calcium SQ26991	Angiotensin-converting Enzyme (ACE) Reactive Oxygen Species	Cardiovascular Disease
Zofenopril Calcium (SQ26991) is an orally active angiotensin-converting enzyme (ACE) inhibitor with antioxidant activity and cardioprotective effects. Zofenopril Calcium reduces ROS production and GSH consumption and helps inhibit foam cell formation, thus slowing the progression of atherosclerosis. Zofenopril Calcium prevents cardiac damage caused by chronic Doxorubicin (HY-15142A).

HY-N6869

Dehydroabietic acid	Antibiotic PPAR Bacterial Fungal	Infection Metabolic Disease Inflammation/Immunology Cancer
Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .

HY-16688

RU 24969 1 Publications Verification	5-HT Receptor	Neurological Disease
RU 24969 is a preferential 5-HT_1B agonist, with a K_i of 0.38 nM, but also displays appreciable affinity for the 5-HT_1A receptor (K_i=2.5 nM), and has low affinity for other receptor sites in the brain. RU 24969 could decrease fluid consumption and increase forward locomotion .

Cat. No.	Product Name

HY-L094

Food-Sourced Compound Library

2,009 compounds

The health benefits deriving from the consumption of certain foods have been common knowledge. All foods are made up of chemical substances. Chemicals in foods are largely harmless and often desirable. At present, numerous researchers have been focused on the beneficial role played by certain food components in the close relationship between food intake and health status. For example, polyphenols, a common class of compounds among foods, are well-known antioxidants, which may play a role in the prevention of several diseases including type 2 diabetes, cardiovascular diseases, and some types of cancer.

MCE supplies a unique collection of 2,009 compounds from variety of foods. All compounds are with specific food source(s). MCE Food-Sourced Compound Library is the useful tool to discover molecules with pharmaceutical activity from foods.

HY-L103

Anti-Colorectal Cancer Compound Library

1,817 compounds

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, arises as adenocarcinoma from glandular epithelial cells of the large intestine comprised of the colon and rectum. The majority of cases of CRC are sporadic and result from risk factors, such as a sedentary lifestyle, obesity, processed diets, alcohol consumption and smoking. CRC is also a common preventable cancer.

Studies showed several cellular signaling pathways dysregulated in CRC, leading to the onset of malignant phenotypes. Therefore, it is necessary to analyze the signaling pathways involved in the occurrence and development of colorectal cancer to study the progression and drug treatment of colorectal cancer. Among them, Wnt/β-catenin, p53, TGF-β/SMAD, NF-κB, Notch, VEGF and other target genes and signaling pathways are the focus of research. MCE offers a unique collection of 1,817 compounds with identified and potential anti-colorectal cancer activity. MCE anti-colorectal cancer compound library is a useful tool for anti-colorectal cancer drugs screening and other related research.

Cat. No.	Product Name	Target	Research Area

HY-P1723A

Spexin TFA Neuropeptide Q TFA	Neuropeptide Y Receptor	Metabolic Disease
Spexin TFA is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC₅₀ values are 45.7 and 112.2 nM, respectively). Spexin TFA exhibits no significant activity at galanin receptor 1. Spexin TFA is an endogenous satiety-inducing peptide; Spexin TFA inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Spexin TFA attenuates LH secretion in goldfish. Spexin TFA exhibits anxiolytic effects in vivo.

HY-P10622

SHLP-3	Apoptosis Reactive Oxygen Species	Metabolic Disease Cancer
SHLP-3 is a mitochondrial derived peptide encoded by the 16S ribosomal RNA (MT-RNR2) gene. SHLP-3 increases cell viability and reduces apoptosis in insulinoma NIT-1β cells and human prostate cancer 22Rv1 cells. SHLP-3 increases mitochondrial function and exerts cytoprotective effects by increasing mitochondrial oxygen consumption rate (OCR), cellular ATP and reducing the ability to produce ROS. SHLP-3 can be used in the study of diabetes and cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W017007

3-Methyl-L-histidine	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
3-Methyl-L-histidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.

HY-W041019

5-Hydroxytryptophol	Structural Classification Natural Products Monophenols Classification of Application Fields Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.

HY-113340

2-Furoylglycine	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Furoylglycine, a urinary metabolite in human, is a putative biomarker for coffee consumption .

HY-33893

Indole-3-methanamine	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Indole-3-methanamine is a potential biomarker for the consumption of these foods such as barley, cereals, and cereal product .

HY-W016509

epi-Inositol	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
epi-Inositol is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Ethanol Consumption .

HY-W015560

3,5-Dihydroxybenzoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses.

HY-126752

Ophthalmic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reactive Oxygen Species
Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction .

HY-N0018

Daidzin 5 Publications Verification Daidzoside; NPI-031D; Daidzein 7-O-glucoside	Structural Classification Monophenols Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Source classification Other Diseases Phenols Plants Disease Research Fields Isoflavones	Mitochondrial Metabolism Reverse Transcriptase Aldehyde Dehydrogenase (ALDH)
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .

HY-W007426

N-Methylbenzylamine	Alkaloids Classification of Application Fields Other Alkaloids Source classification Ephedraceae Other Diseases Plants Disease Research Fields Ephedra sinica Stapf	Others
N-methylbenzylamine is a member of phenylmethylamines. N-methylbenzylamine can be found in carrot, which makes N-methylbenzylamine a potential biomarker for the consumption of these food products .

HY-114976

S-Allylmercapturic acid	Structural Classification Natural Products Source classification Allium sativum L. Plants Amaryllidaceae	Drug Metabolite
S-Allylmercapturic acid is a biomarker of food intake (BFIs) for garlic consumption .

HY-N12169

Janthitrem A 11,12-Epoxyjanthitrem B	Structural Classification Alkaloids Microorganisms Source classification Indole Alkaloids	Others
Janthitrem A (11,12-Epoxyjanthitrem B) is a natural product that can be isolated from Penicillium janthinellum. Janthitrem A induces tremors in mice and reduces weight gain and food consumption of porina (Wiseana cervinata) larvae .

HY-N7176

Kaempferol 3-O-β-D-glucuronide 2 Publications Verification Kaempferol-3-glucuronide; Kaempferol-3-O-glucuronide	Flavonols Structural Classification Flavonoids Microorganisms other families Classification of Application Fields Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Interleukin Related
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism .

HY-N0018R

Daidzin (Standard)	Structural Classification Monophenols Flavonoids Leguminosae Glycine max (L.) merr Source classification Phenols Plants Isoflavones	Mitochondrial Metabolism Reverse Transcriptase Aldehyde Dehydrogenase (ALDH)
Daidzin (Standard) is the analytical standard of Daidzin. This product is intended for research and analytical applications. Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .

HY-N2953

Borapetoside E	Structural Classification Natural Products Source classification Plants Menispermaceae Tinospora crispa (L.) Hook. f. et Thoms	Fatty Acid Synthase (FASN)
Borapetoside E can be isolated from T. crispa. Borapetoside E improves hyperglycemia, insulin resistance, hepatic steatosis, hyperlipidemia, and oxygen consumption in obese mice. Borapetoside E also inhibits SREBPs expression in the liver and adipose tissue .

HY-W015560R

3,5-Dihydroxybenzoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Endogenous metabolite	Endogenous Metabolite
3,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 3,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses.

HY-N2086R

Ethyl palmitate (Standard)	Structural Classification Natural Products Microorganisms Source classification Dicerothamnus rhinocerotis Umbelliferae Plants	Others
Ethyl palmitate (Standard) is the analytical standard of Ethyl palmitate. This product is intended for research and analytical applications. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .

HY-N6869

Dehydroabietic acid	Infection Structural Classification Microorganisms other families Classification of Application Fields Anti-aging Terpenoids Source classification Diterpenoids Plants Inflammation/Immunology Disease Research Fields	Antibiotic PPAR Bacterial Fungal
Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .

HY-N6869R

Dehydroabietic acid (Standard)	Structural Classification Microorganisms other families Terpenoids Source classification Diterpenoids Plants	Antibiotic PPAR Bacterial Fungal
Dehydroabietic acid (Standard) is the analytical standard of Dehydroabietic acid. This product is intended for research and analytical applications. Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .

Cat. No.	Product Name	Chemical Structure

HY-W041019S

5-Hydroxytryptophol-d4
5-Hydroxytryptophol-d₄ is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.

HY-W007426S

N-Methylbenzylamine-d3
N-Methylbenzylamine-d₃ is the deuterium labeled N-Methylbenzylamine[1]. N-methylbenzylamine is a member of phenylmethylamines. N-methylbenzylamine can be found in carrot, which makes N-methylbenzylamine a potential biomarker for the consumption of these food products[2].

HY-N2086S

Ethyl palmitate-d31
Ethyl palmitate-d₃₁ is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent[1].

HY-W017007S

3-Methyl-L-histidine-d3
3-Methyl-L-histidine-d₃ is the deuterium labeled 3-Methyl-L-histidine. 3-Methyl-L-histidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.

HY-W014118S

α-Hexylcinnamaldehyde-d5
α-Hexylcinnamaldehyde-d₅ is deuterated labeled Diacetoxyscirpenol (HY-N6692). Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals .

HY-132184S

5,6-Epoxyeicosatrienoic acid-d11

5,6-Epoxyeicosatrienoic acid-d₁₁ (5,6-EET-d₁₁) is deuterium labeled 5,6-Epoxyeicosatrienoic acid. 5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 (IC₅₀=0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2, as measured by oxygen consumption and product formation assays when used at a concentration of 50 μM. (±)5,6-Epoxyeicosatrienoic acid is provided as a mixture of the free acid and lactone .

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