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Results for "

delivering mRNA

" in MedChemExpress (MCE) Product Catalog:

30

Inhibitors & Agonists

14

Biochemical Assay Reagents

3

Peptides

1

Click Chemistry

14

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-159855
    CAP 2 hydrochloride

    Cholesterol-amino-phosphate 2 hydrochloride

    		 Liposome Others
    CAP 2 (Cholesterol-amino-phosphate 2) hydrochloride is Cholesterol-amino-phosphate (CAP) lipid. CAP 2 can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    CAP 2 hydrochloride
  • HY-139306
    BAMEA-O16B

    		Liposome Inflammation/Immunology
    BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .
    BAMEA-O16B
  • HY-156857
    PPZ-A10

    		Liposome Inflammation/Immunology
    PPZ-A10 is a ionizable lipid that delivered mRNA preferentially to liver and spleen immune cells.
    PPZ-A10
  • HY-134780
    L-369

    		Liposome Others
    L-369 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles and deliver mRNA .
    L-369
  • HY-159865
    CL15F6

    		Liposome Others
    CL15F6 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    CL15F6
  • HY-159856
    16:0 Cardiolipin

    Diphosphatidylglycerol (16:0)

    		 Liposome Others
    16:0 Cardiolipin (Diphosphatidylglycerol (16:0)) is a phospholipid derived from Palmitic acid (16:0) that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    16:0 Cardiolipin
  • HY-159862
    IM21.7c

    		Liposome Infection
    IM21.7c is a cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    IM21.7c
  • HY-159853
    C14-A1

    		Liposome Inflammation/Immunology
    C14-A1 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    C14-A1
  • HY-159854
    C14-O2

    		Liposome Cancer
    C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    C14-O2
  • HY-159858
    Lipid 16

    		Liposome Cancer
    Lipid 16 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads. Lipid 16 as a potent cell type-specific ionizable lipid for the CD11bhi macrophage population without an additional targeting moiety .
    Lipid 16
  • HY-160908
    Lipid 88

    		Liposome Others
    Lipid 88 is an ionizable cationic lipid. Lipid 88 can be used to synthesize lipid nanoparticles and deliver mRNA .
    Lipid 88
  • HY-160512
    Lipid 9

    		Liposome Others
    Lipid 9 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    Lipid 9
  • HY-132289
    Lipid M

    		Liposome Inflammation/Immunology
    Lipid M (pKa: 6.75) can be used to deliver mRNA vaccine and yield a robust immune response with improved tolerability .
    Lipid M
  • HY-151508
    Diamino lipid DAL4

    		Liposome Cancer
    Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .
    Diamino lipid DAL4
  • HY-159869
    G0-C14 analog

    		Liposome Others
    G0-C14 analog is a G0-C14 derivative. G0-C14 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) .
    G0-C14 analog
  • HY-156936
    RCB-02-4-8

    		Liposome Others
    RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
    RCB-02-4-8
  • HY-153737
    113-N16B

    		Liposome Others
    113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
    113-N16B
  • HY-151507
    306Oi10

    		Liposome Others
    306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
    306Oi10
  • HY-W440897
    DSPE-PEG-SH (MW 3400)

    		Biochemical Assay Reagents Others
    DSPE-PEG-SH, MW 3400 is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA. Reagent grade, for research use only.
    DSPE-PEG-SH (MW 3400)
  • HY-145405
    C12-200
    10+ Cited Publications

    		 Liposome Others
    C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
    C12-200
  • HY-W440928
    Stearic acid-PEG-NHS (MW 3400)

    		Biochemical Assay Reagents Liposome Others
    DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.
    Stearic acid-PEG-NHS (MW 3400)
  • HY-134541
    SM-102
    20+ Cited Publications

    		 Liposome Infection
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102
  • HY-W440834
    DSPE-PEG-azide (MW 5000)

    		Biochemical Assay Reagents Liposome Others
    DSPE-PEG-Azide, MW 5000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-azide (MW 5000)
  • HY-151506
    Phospholipid PL1

    		Liposome Cancer
    Phospholipid PL1 is a phospholipid-derived nanoparticle, can deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Phospholipid PL1 could induce the activation of various immune cells, including T cells and dendritic cells (DCs) in order to boost antitumor immunity .
    Phospholipid PL1
  • HY-134541A
    SM-102 (Excipient)

    		Liposome Infection
    SM-102 Excipient is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 Excipient has higher transfection efficiency. SM-102 Excipient plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102 (Excipient)
  • HY-147332
    TCL053

    		Liposome Neurological Disease
    TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
    TCL053
  • HY-W440904
    DSPE-PEG-Vinylsulfone (MW 1000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-Vinylsulfone, MW 1000 is a self-assembling PEG reagent which forms lipid bilayer. The amphiphilic polymer can be used to prepare liposome for delivering therapeutics, such as nucleic acid (mRNA/DNA) or protein. The vinyl sulfone moiety is reactive with cysteine or other thiol molecule via thiol-ene chemistry. Reagent grade, for research use only.
    DSPE-PEG-Vinylsulfone (MW 1000)
  • HY-P6020
    HBpep-SA

    		Biochemical Assay Reagents Others
    HBpep-SA is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines .
    HBpep-SA
  • HY-P6020B
    HBpep-SA acetate

    		Biochemical Assay Reagents Others
    HBpep-SA acetate is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA acetate is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA acetate can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines .
    HBpep-SA acetate
  • HY-147081
    AS 1411

    AGRO-100

    		 Histone Methyltransferase Bcl-2 Family Cancer
    AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. AS 1411 works by blocking the binding of nucleoproteins to bcl-2 mRNA in MCF-7 breast cancer cells. AS 1411-coupled Jin nanospheres can inhibit breast cancer cell proliferation in vitro and in mouse models, has the ability to cross the blood-brain barrier with low tissue toxicity .
    AS 1411