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Results for "

fatty acid derivative

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Drug Derivative (5) FATP (1) Acyltransferase (1) Aminotransferases (Transaminases) (1) Apoptosis (1) Autophagy (1) Bacterial (1) Bcl-2 Family (1) Biochemical Assay Reagents (6) CDK (1) Cholinesterase (ChE) (1) COX (1) Cyclin G-associated Kinase (GAK) (1) Cytochrome P450 (1) Drug Intermediate (2) Endogenous Metabolite (5) ERK (1) Ferroptosis (1) Fluorescent Dye (3) Glutathione S-transferase (1) HBV (1) HCV (1) HSP (1) Interleukin Related (1) Isotope-Labeled Compounds (2) JNK (1) Liposome (1) Microtubule/Tubulin (1) mTOR (1) NF-κB (2) P-glycoprotein (1) p38 MAPK (1) Reactive Oxygen Species (1) TNF Receptor (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (5) Metabolic Disease (12) Neurological Disease (2)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Cationic Lipids (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Targets Recommended: Drug Derivative Free Fatty Acid Receptor Fatty Acid Synthase (FASN) FATP FABP FAAH Amino acid Transporter ELOVL Amino Acid Derivatives Amino Acid Decarboxylase Hydroxycarboxylic Acid Receptor (HCAR) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-126172

9-Anthryldiazomethane	Fluorescent Dye	Cancer
9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives .

HY-141700

FATP1-IN-2 2 Publications Verification	FATP	Metabolic Disease
FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC₅₀=0.43 μM, mouse IC₅₀=0.39 μM) .

HY-119647

PPOH	COX Cytochrome P450	Others
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC₅₀ values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W015881

Dimebutic acid NSC-16045; NSC-741804	Drug Intermediate	Others
Dimebutic acid is a fatty acid derivative .

HY-W923357

9(Z),11(Z)-Conjugated linoleic acid methyl ester 9Z,11Z-CLA	Drug Derivative	Metabolic Disease
9(Z),11(Z)-Conjugated linoleic acid methyl ester is a fatty acid derivative and a form of conjugated linoleic acid methyl ester .

HY-113434B

5-HETE (±)-5-HETE	Endogenous Metabolite	Inflammation/Immunology
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC₅₀ value of 200 nM .

HY-W015881A

Dimebutic acid sodium NSC-16045 sodium; NSC-741804 sodium	Drug Intermediate	Others
Dimebutic acid sodium is a fatty acid derivative .

HY-113069

Decanoylcarnitine	Endogenous Metabolite	Metabolic Disease
Decanoylcarnitine is a fatty ester lipid and an acylcarnitine derivative, which is a metabolite associated with impaired fatty acid metabolism in the elderly population .

HY-N2644

4-Oxododecanedioic acid	Others	Others
4-Oxododecanedioic acid is a fatty acid derivative .

HY-145503

Decanoyl-L-carnitine chloride	Drug Derivative	Metabolic Disease
Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism .

HY-N7861

Methyl elaidate Methyl trans-9-Octadecenoate; (E)-Methyl octadec-9-enoate	Biochemical Assay Reagents	Others
Methyl elaidate is a compound belonging to the class of fatty acid esters. It is derived from elaidic acid, a monounsaturated omega-9 fatty acid found in certain vegetable oils and animal fats. Methyl elaidate is commonly used as a reference compound for the analysis of fatty acids and their derivatives by gas chromatography.

HY-E70274

17:1(n7) Coenzyme A triammonium	Others	Metabolic Disease
17:1(n7) Coenzyme A triammonium is a derivative of fatty acyl-CoA .

HY-101722

Melinamide AC 223; DL-N-(α-Methylbenzyl)linoleamide	Acyltransferase	Metabolic Disease
Melinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC₅₀ of 20.9 μM.

HY-E70269

(11Z-Octadecenoyl)-CoA triammonium	Biochemical Assay Reagents	Others
(11Z-Octadecenoyl)-CoA triammonium is a derivative of Monounsaturated fatty acid oleic acid (18:1 n7) CoA.

HY-127139

Eicosapentaenoyl Chloride Eicosapentaenoic acid Chloride; EPA Chloride	Endogenous Metabolite	Metabolic Disease
Eicosapentaenoyl chloride is a derivative of eicosapentaenoic acid. It has been used in the synthesis of fatty acid conjugates to enhance lipophilicity and cell permeability of bioactive compounds such as (–)-epigallocatechin gallate and salicylic acid.

HY-N7861R

Methyl elaidate (Standard)	Biochemical Assay Reagents	Others
Methyl elaidate (Standard) is the analytical standard of Methyl elaidate. This product is intended for research and analytical applications. Methyl elaidate is a compound belonging to the class of fatty acid esters. It is derived from elaidic acid, a monounsaturated omega-9 fatty acid found in certain vegetable oils and animal fats. Methyl elaidate is commonly used as a reference compound for the analysis of fatty acids and their derivatives by gas chromatography.

HY-130405

PtdIns-(1,2-dipalmitoyl) ammonium	Drug Derivative	Metabolic Disease
PtdIns-(1,2-dipalmitoyl) ammonium (DPPI) is a derivative of phosphatidylinositol (PtdIns) that contains C16:0 fatty acyl chains .

HY-145503S

Decanoyl-L-carnitine-d9 chloride	Isotope-Labeled Compounds Others	Metabolic Disease
Decanoyl-L-carnitine-d₉ (chloride) is deuterium labeled Decanoyl-L-carnitine (chloride). Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism .

HY-W923496

all-cis-4,7,10,13,16-Docosapentaenoic acid ethyl ester SFE 24:5; all-cis-4,7,10,13,16-DPA Ethyl ester	Drug Derivative	Others
all-cis-4,7,10,13,16-Docosapentaenoic acid ethyl ester (SFE 24:5) is a derivative of Docosapentaenoic acid (DPA). DPA is a fatty acid found in fish oils .

HY-134136

Octanoyl Coenzyme A	Endogenous Metabolite	Metabolic Disease
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-107840

RGW-611	Others	Others
RGW 611 is a morpholine derivative that enhances radiation-induced cell death of hypoxic V79-379A cells. RGW 611 also stimulates fatty acid synthesis .

HY-134136A

Octanoyl coenzyme A lithium	Biochemical Assay Reagents	Cancer
Octanoyl coenzyme A lithium is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A lithium can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-W009118

Fmoc-5-Ava-OH	Amino Acid Derivatives	Others
Fmoc-5-Ava-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize fatty acid-based dimeric peptides with PSD-95 inhibitory activity .

HY-109089S

Epeleuton-d5 15(S)-HEPE-d₅ ethyl ester; 15(S)-Hydoxy EPA-d₅ ethyl ester; 15(S)-Hydoxy eicosapetaeoic acid-d₅ ethyl ester	Isotope-Labeled Compounds Others	Others
Epeleuton-d₅ (15(S)-HEPE-d₅ ethyl ester) is deuterium labeled Epeleuton. Epeleuton is a second-generation synthetic N-3 fatty acid derivative with activity in patients with non-alcoholic fatty liver disease, although it did not reach the primary endpoints of alanine aminotransferase and liver stiffness, but it can significantly reduce triglycerides, glycated hemoglobin, plasma glucose and inflammatory markers .

HY-E70267

22:0 Coenzyme A triammonium	Biochemical Assay Reagents	Metabolic Disease
22:0 Coenzyme A triammonium is a derivative of coenzyme A (CoA), where CoA is combined with a 22-carbon saturated fatty acid (behenic acid, also known as docosanoic acid). 22:0 Coenzyme A triammonium can serve as a substrate for AmFAR1 .

HY-135808

BIZ 114	NF-κB	Inflammation/Immunology
BIZ 114 (Example 11) is a fatty acid derivative and potent inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and / or treat ophthalmic disorders such as retinal degenerative disorders and ocular inflammatory diseases .

HY-D0133

NBD-X acid	Fluorescent Dye	Others
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions .

HY-D1336

FAM amine, 6-isomer	Fluorescent Dye
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.

HY-149505

(±)-10-Hydroxy-12(Z),15(Z)-octadecadienoic acid 12(Z),15(Z)-10-HODE; (±)-10-Hydroxy-12(Z),15(Z)-ODE	Biochemical Assay Reagents	Others
(±)-10-Hydroxy-12(Z),15(Z)-octadecadienoic acid is a fatty acid derivative. (±)-10-Hydroxy-12(Z),15(Z)-octadecadienoic acid can be used in the food, cosmetic and pharmaceutical industries, such as starting materials for biodegradable polymers, lubricants, emulsifiers, drugs and fragrances .

HY-109089

Epeleuton	Others	Others
Epeleuton is a second-generation synthetic n-3 fatty acid derivative that mainly targets the regulation of blood lipids, blood sugar and inflammatory responses. In clinical trials, Epeleuton significantly reduced triglycerides, very low-density lipoprotein cholesterol and total cholesterol without increasing low-density lipoprotein cholesterol levels. Epeleuton also significantly improved glycated hemoglobin (HbA1c) and fasting blood sugar levels. Epeleuton reduces markers of cardiovascular risk and endothelial dysfunction and has the potential to inhibit systemic inflammation and non-alcoholic fatty liver disease .

HY-121212

Icosabutate	Aminotransferases (Transaminases)	Metabolic Disease Inflammation/Immunology
Icosabutate, an orally active ω-3 polyunsaturated fatty acid, is an aeicosapentaenoic acid (EPA) derivative. Icosabutate overcomes the drawbacks of unmodified EPA for liver targeting and improves insulin sensitivity, hepatic inflammation and fibrosis . Icosabutate is well tolerated, and efficacious in lowering non-high-density lipoprotein cholesterol (non-HDL-C) levels in persistent?hypertriglyceridemia? .

HY-122643

NITD-916	Bacterial	Infection
NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active and highly lipophilic mycobacterial enoyl reductase InhA inhibitor with an IC₅₀ of 570 nM. NITD-916 forms a ternary complex with InhA and NADH to block access to the fatty acyl substrate binding pocket. NITD-916 has potent anti-tuberculosis effects .

HY-W347368

9Z,11E,13Z-Octadecatrienoicacid, methylester Methyl punicate	Endogenous Metabolite	Cancer
9Z,11E,13Z-Octadecatrienoicacid, methylester (Methyl punicate) is a fatty acid methyl ester, which can be isolated from seeds of Punica granatum L.. 9Z,11E,13Z-Octadecatrienoicacid, methylester exhibits antitumor efficacy, which interferes with tumor cell cycle, drug resistance and angiogenesis. 9Z,11E,13Z-Octadecatrienoicacid, methylester is the derivative of Punicic acid (HY-139066) .

HY-W746625

all-cis-4,7,10,13,16-Docosapentaenoic acid methyl ester all-cis-4,7,10,13,16-DPA methyl ester	Drug Derivative	Cardiovascular Disease Neurological Disease Inflammation/Immunology
all-cis-4,7,10,13,16-Docosapentaenoic acid methyl ester (all-cis-4,7,10,13,16-DPA methyl ester) is the methyl ester derivative of all-cis-4,7,10,13,16-Docosapentaenoic acid, that can be used as a nutritional supplement to increase all-cis-4,7,10,13,16-Docosapentaenoic acid intake. all-cis-4,7,10,13,16-Docosapentaenoic acid is a long-chain polyunsaturated fatty acid, that plays a role in cardiovascular health, neuroprotection, and inflammation regulation .

HY-W127378

DOTAP methylsulfate 5+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate	Liposome	Others
DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].

HY-116153

HUHS2002	Cholinesterase (ChE)	Neurological Disease
HUHS2002 is a free fatty acid derivative with the ability to enhance α7 cholinergic receptor activity. HUHS2002 enhances whole-cell membrane currents of α7 ACh receptors expressed in Xenopus oocytes in a concentration-dependent manner. The effects of HUHS2002 were blocked in the presence of the Ca2?/calmodulin-dependent protein kinase II (CaMKII) inhibitor KN-93. HUHS2002 activated CaMKII in cultured rodent hippocampal neurons, and this activation was abolished by KN-93. HUHS2002 also partially inhibited the activity of protein phosphatase 1 (PP1) in a cell-free PP1 activity assay .

HY-B0766

Bicyclol SY801	Autophagy Apoptosis HBV HCV HSP Reactive Oxygen Species Bcl-2 Family Glutathione S-transferase p38 MAPK NF-κB Microtubule/Tubulin ERK JNK TNF Receptor Interleukin Related CDK Cyclin G-associated Kinase (GAK) mTOR P-glycoprotein Ferroptosis	Infection Inflammation/Immunology Cancer
Bicyclol (SY801) is an orally active derivative of the traditional Chinese medicine Schisandra chinensis, which has antiviral, anti-inflammatory, immunomodulatory, antioxidant, anti-steatosis, anti-fibrotic and anti-tumor activities. Bicyclol regulates the expression of heat shock proteins and plays an anti-apoptosis role in hepatocytes. Bicyclol reduces the activation of NF-κB and the levels of inflammatory factors in hepatocytes infected with hepatitis C virus (HCV) by inhibiting the activation of the ROS-MAPK-NF-κB pathway, and prevents ferroptosis in acute liver injury. Bicyclol can change the expression of Mdr-1, GSH/GST and Bcl-2, increase the intracellular concentration of anticancer drugs, and sensitize drug-resistant cells to anticancer drugs. Bicyclol inhibits the proliferation of human malignant hepatoma cells by regulating the PI3K/AKT pathway and the Ras/Raf/MEK/ERK pathway. Bicyclol can be used in the study of chronic hepatitis, acute liver injury, nonalcoholic fatty liver disease, liver fibrosis and hepatocellular carcinoma .

Cat. No.	Product Name	Type

HY-126172

9-Anthryldiazomethane	Fluorescent Dyes/Probes
9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives .

HY-D0133

NBD-X acid	Fluorescent Dyes/Probes
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions .

HY-D1336

FAM amine, 6-isomer	Fluorescent Dyes/Probes
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.

Cat. No.	Product Name	Type

HY-134136A

Octanoyl coenzyme A lithium	Enzyme Substrates
Octanoyl coenzyme A lithium is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A lithium can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-W127378

DOTAP methylsulfate 5+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate	Drug Delivery
DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].

DOTAP methylsulfate

5+ Cited Publications

1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate

Drug Delivery

DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].

HY-N7861

Methyl elaidate Methyl trans-9-Octadecenoate; (E)-Methyl octadec-9-enoate	Drug Delivery
Methyl elaidate is a compound belonging to the class of fatty acid esters. It is derived from elaidic acid, a monounsaturated omega-9 fatty acid found in certain vegetable oils and animal fats. Methyl elaidate is commonly used as a reference compound for the analysis of fatty acids and their derivatives by gas chromatography.

HY-N7861R

Methyl elaidate (Standard)	Drug Delivery
Methyl elaidate (Standard) is the analytical standard of Methyl elaidate. This product is intended for research and analytical applications. Methyl elaidate is a compound belonging to the class of fatty acid esters. It is derived from elaidic acid, a monounsaturated omega-9 fatty acid found in certain vegetable oils and animal fats. Methyl elaidate is commonly used as a reference compound for the analysis of fatty acids and their derivatives by gas chromatography.

Methyl elaidate (Standard)

Drug Delivery

Methyl elaidate (Standard) is the analytical standard of Methyl elaidate. This product is intended for research and analytical applications. Methyl elaidate is a compound belonging to the class of fatty acid esters. It is derived from elaidic acid, a monounsaturated omega-9 fatty acid found in certain vegetable oils and animal fats. Methyl elaidate is commonly used as a reference compound for the analysis of fatty acids and their derivatives by gas chromatography.

HY-134136

Octanoyl Coenzyme A	Enzyme Substrates
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

Cat. No.	Product Name	Target	Research Area

HY-W009118

Fmoc-5-Ava-OH	Amino Acid Derivatives	Others
Fmoc-5-Ava-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize fatty acid-based dimeric peptides with PSD-95 inhibitory activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113434B

5-HETE (±)-5-HETE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC₅₀ value of 200 nM .

HY-113069

Decanoylcarnitine	Structural Classification Natural Products Source classification Disease markers Endogenous metabolite	Endogenous Metabolite
Decanoylcarnitine is a fatty ester lipid and an acylcarnitine derivative, which is a metabolite associated with impaired fatty acid metabolism in the elderly population .

HY-N2644

4-Oxododecanedioic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Pteridaceae Coniogramme japonica (Thunb.) Diels Plants	Others
4-Oxododecanedioic acid is a fatty acid derivative .

Cat. No.	Product Name	Chemical Structure

HY-145503S

Decanoyl-L-carnitine-d9 chloride
Decanoyl-L-carnitine-d₉ (chloride) is deuterium labeled Decanoyl-L-carnitine (chloride). Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism .

HY-109089S

Epeleuton-d5

Epeleuton-d₅ (15(S)-HEPE-d₅ ethyl ester) is deuterium labeled Epeleuton. Epeleuton is a second-generation synthetic N-3 fatty acid derivative with activity in patients with non-alcoholic fatty liver disease, although it did not reach the primary endpoints of alanine aminotransferase and liver stiffness, but it can significantly reduce triglycerides, glycated hemoglobin, plasma glucose and inflammatory markers .

Cat. No.	Product Name		Classification

HY-119647

PPOH		Alkynes
PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC₅₀ values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-W127378

DOTAP methylsulfate 5+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate		Cationic Lipids
DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].

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fatty acid derivative

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Natural
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