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Results for "

fibrosarcoma

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (3) Endogenous Metabolite (1) Ferroptosis (4) Furin (2) PKA (1) PKC (1) PPAR (1) Raf (4) STAT (1)
By Research Areas:	Cancer (16) Cardiovascular Disease (2) Infection (3) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (3)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013523

2-NP 4 Publications Verification	STAT	Cancer
2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells .

HY-W047478

3-Methylcarbazole NSC 10154	Others	Cancer
3-Methylcarbazole is an carbazole alkaloid compound with anticancer effects. 3-Methylcarbazole shows growth inhibitory activity (IC₅₀ of 25 μg/mL) on human fibrosarcoma HT-1080 cells .

HY-109080

Belvarafenib 3 Publications Verification HM95573; GDC-5573; RG6185	Raf	Cancer
Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC₅₀s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAF ^v600E and C-RAF respectively .

HY-162449

GIC-20	Apoptosis Ferroptosis	Cancer
GIC-20 is a dual inducer for apoptosis and ferroptosis. GIC-20 exhibits antitumor efficacy against fibrosarcoma .

HY-N10158

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one	Others	Cancer
1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one (compound 39), a diarylheptanoid, exhibits antiproliferative activity towards human HT-1080 fibrosarcoma and murine colon 26-L5 carcinoma cells .

HY-159534

Flezurafenibum Flezurafenib	Raf	Cancer
Flezurafenibum (Flezurafenib) is a rapidly accelerated fibrosarcoma (Raf) kinase inhibitor, with antineoplastic effect .

HY-159508

Brimarafenibum Brimarafenib	Raf	Cancer
Brimarafenibum (Brimarafenib) is a rapidly accelerated fibrosarcoma (Raf) kinase inhibitor, wtih antineoplastic effect .

HY-130201

Deacetylsaptomycin D	Others	Cancer
Deacetylsaptomycin D is a deacetylated saptomycin with in vitro antitumor activity. Deacetylsaptomycin D inhibits the growth of mouse methoxy-A fibrosarcoma cells .

HY-N3215

Nagilactone C	Others	Others
Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines .

HY-109080A

Belvarafenib TFA HM95573 TFA; GDC-5573 TFA; RG6185 TFA	Raf	Cancer
Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC₅₀s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv ^600E and C-RAF respectively .

HY-100279

RMI 10874	Antibiotic	Infection Cancer
RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone.

HY-116087

SRS11-92	Ferroptosis	Neurological Disease Cancer
SRS11-92, a Ferrostatin-1 (Fer-1) analogue, is a potent ferroptosis inhibitor. SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells (EC₅₀=6 nM) .

HY-E70293

N-Acetylgalactosaminyltransferase 12 GALNT12	Endogenous Metabolite	Cancer
N-Acetylgalactosaminyltransferase 12 (GALNT12) belongs to the uridine diphosphate N-acetylgalactosamine gene family and is involved in the biological processes of many diseases, such as tumor progression. N-Acetylgalactosaminyltransferase 12 is a potential biomarker for fibrosarcoma, and its high expression level is closely related to the yes1-associated transcriptional regulator (YAP1) signaling pathway .

HY-B0581

Dexrazoxane Maximum Cited Publications 10 Publications Verification ICRF-187; ADR-529; NSC-169780	Ferroptosis Apoptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells .

HY-155619

Protein kinase inhibitor 7	PKC PKA	Cancer
Protein kinase inhibitor 7 is an inhibitor for protein kinase A and protein kinase C. Protein kinase inhibitor 7 affects autocrine motility factor (AMF) signaling pathway, without affecting the cell motility .

HY-B0581R

Dexrazoxane (Standard)	Ferroptosis Apoptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Dexrazoxane (Standard) is the analytical standard of Dexrazoxane. This product is intended for research and analytical applications. Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells .

HY-17444

Tesaglitazar	PPAR	Metabolic Disease Cancer
Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC₅₀s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively, and approximately 0.2 μM for both rat and human PPARγ. Tesaglitazar induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats .

HY-110147A

SSM3 tetraTFA	Furin	Infection
SSM3 tetraTFA is a potent synthetic furin inhibitor with an EC₅₀ and a K_i of 54 nM and 12 nM, respectively. SSM3 tetraTFA is able to block furin-dependent cell surface processing of anthrax protective antigen-83 in vitro .

HY-110147B

SSM3 tetraTFA hydrate	Furin	Infection
SSM3 tetraTFA hydrate is a potent synthetic furin inhibitor with an EC₅₀ and a K_i of 54 nM and 12 nM, respectively. SSM3 tetraTFA hydrate is able to block furin-dependent cell surface processing of anthrax protective antigen-83 in vitro .

3-Methylcarbazole NSC 10154	Alkaloids other families Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids Cancer	Others
3-Methylcarbazole is an carbazole alkaloid compound with anticancer effects. 3-Methylcarbazole shows growth inhibitory activity (IC₅₀ of 25 μg/mL) on human fibrosarcoma HT-1080 cells .

Nagilactone C	Structural Classification Terpenoids Source classification Diterpenoids Podocarpus sellowii Klotzsch ex Endl. Plants Podocarpaceae	Others
Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81433

	c-Maf Antibody (YA1178) MAF; Transcription factor Maf; Proto-oncogene c-Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog	IHC-P	Human
	c-Maf Antibody (YA1178) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1178), targeting c-Maf. c-Maf Antibody (YA1178) can be used for IHC-P experiment in human background.

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fibrosarcoma

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