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glutamate derivative

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

3

Biochemical Assay Reagents

11

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3

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1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-20167A
    H-Glu(OtBu)-OtBu hydrochloride

    		Neurokinin Receptor Neurological Disease
    H-Glu(OtBu)-OtBu hydrochloride is a glutamate derivative that can be used for substance P antagonist synthesis .
    H-Glu(OtBu)-OtBu hydrochloride
  • HY-W010785
    Dibenzyl L-glutamate tosylate

    		Amino Acid Derivatives Others
    Dibenzyl L-glutamate tosylate is a glutamic acid derivative .
    Dibenzyl L-glutamate tosylate
  • HY-30232
    L-Glutamate-γ-benzyl ester

    		Amino Acid Derivatives Others
    L-Glutamate-γ-benzyl ester is a glutamic acid derivative .
    L-Glutamate-γ-benzyl ester
  • HY-W009229
    Boc-Glu(OtBu)-OH

    		Biochemical Assay Reagents Others
    Boc-Glu(OtBu)-OH is a glutamate derivative, with the protecting group of Boc- and OtBu .
    Boc-Glu(OtBu)-OH
  • HY-11041
    LSP1-2111

    		mGluR Neurological Disease
    LSP1-2111 is a phosphinic glutamate derivative that agonists metabotropic glutamate (mGlu) receptor .
    LSP1-2111
  • HY-Y0749A
    Dimethyl D-glutamate hydrochloride

    Glutamic acid, dimethyl ester, hydrochloride, D-

    		 Amino Acid Derivatives Others
    Dimethyl D-glutamate hydrochloride is a glutamic acid derivative .
    Dimethyl D-glutamate hydrochloride
  • HY-131039
    MDNI-caged-L-glutamate

    MDNI-glu

    		 Amino Acid Derivatives Others
    MDNI-caged-L-glutamate (MDNI-glu) is a biologically inert, photosensitive derivative of the major excitatory amino acid, L-glutamate. MDNI-caged-L-glutamate makes more efficient use of incident light .
    MDNI-caged-L-glutamate
  • HY-124228
    Ethyl glutamate

    		Endogenous Metabolite Others
    Ethyl glutamate is an amino acid derivative that has the activity of promoting cell growth. Ethyl glutamate can be used in research related to the field of life sciences .
    Ethyl glutamate
  • HY-W745139
    5-Octyl D-Glutamate

    		Amino Acid Derivatives Others
    5-Octyl D-Glutamate is aamino acids and their derivatives.
    5-Octyl D-Glutamate
  • HY-W025811
    1-(tert-Butyl) 5-methyl L-glutamate hydrochloride

    		Amino Acid Derivatives Others
    1-(tert-Butyl) 5-methyl L-glutamate hydrochloride is a glutamic acid derivative .
    1-(tert-Butyl) 5-methyl L-glutamate hydrochloride
  • HY-W008326
    Z-Glu(OtBu)-OH

    		Amino Acid Derivatives Others
    Z-Glu(OtBu)-OH is a derivative of glutamate, can be used for molecule, agent, compounds synthesis .
    Z-Glu(OtBu)-OH
  • HY-W588263S1
    Indole-3-acetyl glutamate-d4

    IAGlu-d4

    		 Isotope-Labeled Compounds Others Others
    Indole-3-acetyl glutamate-d4 (IAGlu-d4) is deuterium labeled Indole-3-acetyl glutamate. Indole-3-acetyl glutamate (IAGlu) is a derivative of the plant hormone indole-3-acetic acid (IAA). As a conjugated form of IAA, Indole-3-acetyl glutamate involves in the transport, storage, and homeostatic regulation of IAA within the plant. Indole-3-acetyl glutamate can be used for research into the effects of plant hormones on the growth and development of plants .
    Indole-3-acetyl glutamate-d4
  • HY-W022255
    Fmoc-D-Glu-OH

    D-Fmoc-glutamic acid

    		 Amino Acid Derivatives Others
    Fmoc-D-Glu-OH (D-Fmoc-glutamic acid) is a derivative of glutamate, can be used to prepare supramolecular hydrogels .
    Fmoc-D-Glu-OH
  • HY-20167
    H-Glu(OtBu)-OtBu

    		Amino Acid Derivatives Others
    H-Glu(OtBu)-OtBu is a glutamic acid derivative .
    H-Glu(OtBu)-OtBu
  • HY-W588263
    Indole-3-acetyl glutamate

    IAGlu

    		 Others Others
    Indole-3-acetyl glutamate (IAGlu) is a derivative of the plant hormone indole-3-acetic acid (IAA). As a conjugated form of IAA, Indole-3-acetyl glutamate involves in the transport, storage, and homeostatic regulation of IAA within the plant. Indole-3-acetyl glutamate can be used for research into the effects of plant hormones on the growth and development of plants .
    Indole-3-acetyl glutamate
  • HY-U00127
    Pyridazinediones-derivative-1

    		Others Neurological Disease
    Pyridazinediones-derivative-1 has potential in treating neurodegenerative disorders. It shows an ED50 of 2.1 μM for inhibiting glutamate-induced contractions of isolated guineapig ileum.
    Pyridazinediones-derivative-1
  • HY-134136
    Octanoyl Coenzyme A

    		Endogenous Metabolite Metabolic Disease
    Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC50 values of 0.4-1.6 mM .
    Octanoyl Coenzyme A
  • HY-N8115
    S-(4-Hydroxybenzyl)glutathione

    		Others Neurological Disease
    S-(4-Hydroxybenzyl)glutathione is a glutathione derivative. S-(4-Hydroxybenzyl)glutathione inhibits the in vitro binding of kainic acid to brain glutamate receptors, with an IC50 of 2 μM .
    S-(4-Hydroxybenzyl)glutathione
  • HY-134136A
    Octanoyl coenzyme A lithium

    		Biochemical Assay Reagents Cancer
    Octanoyl coenzyme A lithium is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A lithium can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC50 values of 0.4-1.6 mM .
    Octanoyl coenzyme A lithium
  • HY-101311
    UPF-523

    AIDA

    		 mGluR Inflammation/Immunology Cancer
    UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 μM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis .
    UPF-523
  • HY-15067
    DNQX
    5 Publications Verification

    FG 9041

    		 iGluR Cancer
    DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) .
    DNQX
  • HY-103233
    DNQX disodium salt

    FG 9041 disodium salt

    		 iGluR Cancer
    DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) .
    DNQX disodium salt
  • HY-162340
    Z32439948

    		Cholinesterase (ChE) Neurological Disease
    Z32439948 is a butyrylcholinesterase (BChE) inhibitor (IC50: 1.4 μM, hBChE) and is a derivative of m-sulfamoylbenzamide. Z32439948 also exhibited neuroprotective effects against glutamate in SH-SY5Y cells .
    Z32439948
  • HY-100547
    IEM-1754

    		iGluR Neurological Disease
    IEM-1754, a dicationic adamantane derivative, is a potent blocker of open channels of native ionotropic glutamate receptors including quisqualate-sensitive receptors in insect muscles, NMDAR in cultured rat cortical neurons, and AMPAR in freshly isolated hippocampal cells. IEM-1754 shows anticonvulsant potency in vivo .
    IEM-1754
  • HY-B0778
    Milbemycin oxime
    1 Publications Verification

    		 Antibiotic Parasite Infection
    Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .
    Milbemycin oxime
  • HY-105022
    Sabeluzole

    R 58735

    		 Tau Protein Neurological Disease
    Sabeluzole (R 58735), a benzothiazol derivative, has antiischemic, antiepileptic, and cognitive-enhancing properties. Sabeluzole protects rat hippocampal neurons against NMDA- and glutamate-induced neurotoxicity via preventing tau expression. Sabeluzole enhances memory in rats, and prevents the amnesic effect of Chlordiazepoxide. Sabeluzole can be used fro research of Alzheimer's disease .
    Sabeluzole
  • HY-122723
    GOT1 inhibitor-1
    2 Publications Verification

    		 Reactive Oxygen Species Cancer
    GOT1 inhibitor-1 (compound 2c), a tryptamine-based derivative, acts as a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM. GOT1 plays an important role in energy metabolism and Reactive Oxygen Species (ROS) balance. GOT1 inhibitor-1 can be used for the research of pancreatic ductal adenocarcinoma (PDAC) .
    GOT1 inhibitor-1
  • HY-B0778R
    Milbemycin oxime (Standard)

    		Antibiotic Parasite Infection
    Milbemycin oxime (Standard) is the analytical standard of Milbemycin oxime. This product is intended for research and analytical applications. Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .
    Milbemycin oxime (Standard)
  • HY-120251A
    Leteprinim potassium

    AIT-082

    		 Reactive Oxygen Species Neurological Disease
    Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species .
    Leteprinim potassium
  • HY-120251
    Leteprinim

    AIT-082 free acid

    		 Reactive Oxygen Species Neurological Disease
    Leteprinim (AIT-082 free acid), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim is a hypoxanthine derivative neurotrophic agent. Leteprinim can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species .
    Leteprinim
  • HY-118783
    2-Hexyl-4-pentynoic acid

    (±)-2-Hexyl-4-pentynoic acid

    		 HDAC HSP Neurological Disease
    2-Hexyl-4-pentynoic acid ((±)-2-Hexyl-4-pentynoic acid), valproic acid (VPA) derivative, exhibits potential roles of HDAC inhibition (IC50=13 μM) and HSP70 induction. Potent neuroprotective effects. 2-Hexyl-4-pentynoic acid causes histone hyperacetylation and protect against glutamate-induced excitotoxicity in cultured neurons . 2-Hexyl-4-pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    2-Hexyl-4-pentynoic acid

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