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herbicidal activity

" in MedChemExpress (MCE) Product Catalog:

43

Inhibitors & Agonists

8

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-151604
    Transketolase-IN-3

    		Transketolase Others
    Transketolase-IN-3 is a potent transketolase (TK) inhibitor. Transketolase-IN-3 has herbicidal activity and has inhibitory effects against Digitaria sanguinalis (DS) and Amaranthus retroflexus (AR). Transketolase-IN-3 can be used for the research of herbicides .
    Transketolase-IN-3
  • HY-N10260
    Curvulinic acid

    		Others Others
    Curvulinic acid is a phytotoxic compound, has herbicidal activity .
    Curvulinic acid
  • HY-169011
    Phytoene desaturase-IN-3

    		Herbicide Others
    Phytoene desaturase-IN-3 (compound 8e) is a potent inhibitor of Phytoene desaturase . Phytoene desaturase-IN-3 has herbicidal activity .
    Phytoene desaturase-IN-3
  • HY-162691
    DEP-5

    		Herbicide Others
    DEP-5 is an inhibitor of acetohydroxyacid synthase (AHAS) with an inhibition constant of 39.4 μM. DEP-5 is a diphenyl ether-pyrimidine hybrid with herbicidal activity against the Leptochloa chinensis(L.) Nees .
    DEP-5
  • HY-N14757
    Hydantocidin

    		Endogenous Metabolite Others
    Hydantocidin is an adenylosuccinate synthetase inhibitor and a spiroribofuranose. Hydantocidin can be produced by Streptomyces hygroscopicus. Hydantocidin has strong herbicidal activity toward annual, biennial and perennial weeds .
    Hydantocidin
  • HY-148429
    Antimalarial agent 17

    		Parasite Others
    Antimalarial agent 17 is an antimalarial agent, also acts as a herbicide. Antimalarial agent 17 is photosystem II inhibitor, shows post-emergence herbicidal activity equal to commercial herbicides .
    Antimalarial agent 17
  • HY-116489
    Pyribenzoxim

    LGC-40863

    		 Herbicide Others
    Pyribenzoxim (LGC-40863) is a broad-spectrum herbicide. Pyribenzoxim has a higher safety level in bentgrass and a stronger herbicidal activity on grass weeds .
    Pyribenzoxim
  • HY-155135
    HPPD-IN-1

    		HPPD Others
    HPPD-IN-1 (compound II-3) is a HPPD inhibitor. HPPD-IN-1 shows inhibitory activity of Arabidopsis thaliana HPPD (AtHPPD) with an IC50 value of 0.248 μM, which was superior to that of mesotrione (HY-12853) (0.283 μM) in vitro. HPPD-IN-1 shows excellent herbicidal activity against broadleaf and monocotyledonous weeds .
    HPPD-IN-1
  • HY-169168
    Herbicidal agent 6

    		Transketolase Others
    Herbicidal agent 6 (D15) is a Transketolase (TKL) inhibitor with herbicidal activity .
    Herbicidal agent 6
  • HY-163298
    Herbicidal agent 2

    		Protoporphyrinogen IX oxidase Others
    Herbicidal agent 2 (compound 8d), a herbicide, is a protoporphyrinogen oxidase (PPO) inhibitor. Herbicidal agent 2 exhibits herbicidal activities against broadleaf and monocotyledon weeds .
    Herbicidal agent 2
  • HY-157025
    Herbicidal agent 1

    		Herbicide Others
    Herbicidal agent 1 （(S)-6q）is a herbicidal agent with superior activity than its racemate .
    Herbicidal agent 1
  • HY-158112
    Herbicidal agent 3

    		Herbicide Others
    Herbicidal agent 3 (compound 7A) shows herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus at a dosage of 90 g ai/ha. Herbicidal agent 3 inhibites Setaria viridis TKL (SvTKL) enzyme activity, with the IC50 of 0.740 mg/L .
    Herbicidal agent 3
  • HY-168496
    Herbicidal agent 8

    		Herbicide Others
    Herbicidal agent 8 (Compound 9w) targets the auxin indole-3-acetic acid (IAA), disrupting the physiological activities of plant cells and eventually causing plant death. Herbicidal agent 8 exhibits herbicidal activity against broadleaf weeds and grass weeds .
    Herbicidal agent 8
  • HY-173026
    Herbicidal agent 7

    		Herbicide Others
    Herbicidal agent 7 (Compound 15c) is the inhibitor for protoporphyrinogen IX oxidase (PPO). Herbicidal agent 7 blocks the plant pigment synthesis, exhibiting herbicidal activity against broadleaf weeds (such as Z. elegans and A. theophrasti) and grass weeds (such as S. glauca and E. crusgalli) .
    Herbicidal agent 7
  • HY-157024
    Phytoene desaturase-IN-2

    		Herbicide Others
    PDS-IN-1 is a potent inhibitor of Oryza sativa phytoene desaturase (OsPDS), resulting in herbicidal activity .
    Phytoene desaturase-IN-2
  • HY-157471
    PPO-IN-7

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-7 (compound 35) is a potent inhibitor of protoporphyrinogen oxidase (PPO). PPO-IN-7 shows herbicidal activity .
    PPO-IN-7
  • HY-163910
    Herbicidal agent 5

    		Herbicide Others
    Herbicidal agent 5 (compound B5) is a herbicide that acts on Photosynthetic System II (PS II) .
    Herbicidal agent 5
  • HY-108970
    Bafilomycin D

    		Proton Pump Bacterial Fungal Infection
    Bafilomycin D is a specific inhibitor of vacuolar-type ATPase (V-ATPase). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity .
    Bafilomycin D
  • HY-114991
    Leptospermone

    		HPPD Others
    Leptospermone is a competitive, reversible inhibitor for p-Hydroxyphenylpyruvate dioxygenase (HPPD), with an IC50 of 12.1 μM. Leptospermone exhibits herbicidal activity for its bleaching effect .
    Leptospermone
  • HY-163310
    Transketolase-IN-5

    		Transketolase Others
    Transketolase-IN-5 (compound 6ba) is a transketolase inhibitor. Transketolase-IN-5 shows herbicidal activity for Amaranthus retroflexus, Setariaviridis, Digitaria sanguinalis .
    Transketolase-IN-5
  • HY-120183
    Harzianopyridone

    		Fungal Infection
    Harzianopyridone is a compound that can be isolated from Trichoderma harzianum. Harzianopyridone is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 80 nM. Harzianopyridone has antifungal, antibacterial, and herbicidal activities .
    Harzianopyridone
  • HY-158246
    QPP-I-6

    		Acetyl-CoA Carboxylase Others
    QPP-I-6 is an inhibitor for acetyl-coenzyme A carboxylase (ACCase). QPP-I-6 exhibits herbicidal activity through induction of cell membrane permeability .
    QPP-I-6
  • HY-122414
    Phosalacine

    		Antibiotic Bacterial Fungal Infection
    Phosalacine is a phosphorouscontaining tripeptide herbicidal antibiotic that can be isolated from soil isolate Kitasatosporia phosalacinea KA-338. Phosalacine also shows antibacterial and antifungal activity .
    Phosalacine
  • HY-155465
    HPPD-IN-2

    		HPPD Others
    HPPD-IN-2 (compound 28) is a herbicide based on HPPD inhibitors. HPPD-IN-2 potently targets AtHPPD and exhibits enhanced safety in canola crops .
    HPPD-IN-2
  • HY-172254
    PPO-IN-19

    		Protoporphyrinogen IX oxidase Herbicide Others
    PPO-IN-19 (Compound 7m) is a protoporphyrin IX oxidase (PPO) inhibitor with an IC50 of 124 nM. PPO-IN-19 exhibits herbicidal activity and can be used in agricultural research .
    PPO-IN-19
  • HY-149312
    PPO-IN-3

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-3 (Compound 8ad) is a PPO inhibitor with an KI value of 0.67 nM. PPO-IN-3 has post-emergence herbicidal activity. PPO-IN-3 can be used for weed control .
    PPO-IN-3
  • HY-172260
    PPO-IN-20

    		Protoporphyrinogen IX oxidase Herbicide Others
    PPO-IN-20 (Compound B18) is a Protoporphyrinogen IX oxidase (PPO, protoporphyrinogen IX oxidase) inhibitor, with a Ki value of 10.3 nM for NtPPO. PPO-IN-20 shows broad-spectrum herbicidal activity and can be used for research in the agricultural field .
    PPO-IN-20
  • HY-W422402
    Foramsulfuron

    		Acetolactate Synthase (ALS) Others
    Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .
    Foramsulfuron
  • HY-163284
    SDH-IN-12

    		Succinate Dehydrogenase Fungal Infection
    SDH-IN-12 (compound 9b) is a succinate dehydrogenase inhibitor, which exhibits activity against S. sclerotiorum and C. arachidicola, with EC50s of 0.97 and 2.07 μM, respectively. SDH-IN-12 reveals no significant herbicidal activity against monocotyledonous and dicotyledonous plants .
    SDH-IN-12
  • HY-161503
    PPO-IN-10

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-10 (Compound 4) is a 2-phenylpyridine derivative of pyrrolidone. PPO-IN-10 inhibits protoporphyrinogen IX oxidase (PPO). PPO-IN-10 leads to the formation of photosensitive protoporphyrin IX and the death of weed leaves. PPO-IN-10 can be used in the research of developing new PPO herbicides .
    PPO-IN-10
  • HY-129308
    LS 82-556

    		Herbicide Others
    LS 82-556 is a light and oxygen-dependent herbicide, which leads to degradation of fatty acids, deals structural damage at the cellular membrane level, and results in the bleaching, wilting, and desiccation of leaves and stems. LS 82-556 exhibits herbicidal activity with the presence of chloroplastic pigments .
    LS 82-556
  • HY-170401
    Antibacterial agent 260

    		Bacterial Herbicide Infection
    Antibacterial agent 260 (Compound 4r) exhibits board-spectrum antibacterial activity, inhibits P. aeruginosa and S. aureus with MIC of 0.0076 μM. Antibacterial agent 260 acts as a herbicidal agent, that inhibits the root- and stem-growth of Raphanus sativus L. (radish seed) .
    Antibacterial agent 260
  • HY-B1869
    Metsulfuron-methyl

    		Herbicide Others
    Metsulfuron-methyl is a systemic sulfonylurea herbicide that has been widely used to control broadleaf weeds and annual grasses in rice, corn, wheat, and barley. Metsulfuron-methyl exhibits high herbicidal activity and low mammalian toxicity, with an LD50 for rats exceeding 5000 mg/kg .
    Metsulfuron-methyl
  • HY-19828
    Herboxidiene

    GEX1A

    		 DNA/RNA Synthesis Cancer
    Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .
    Herboxidiene
  • HY-W422402R
    Foramsulfuron (Standard)

    		Acetolactate Synthase (ALS) Others
    Foramsulfuron (Standard) is the analytical standard of Foramsulfuron. This product is intended for research and analytical applications. Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .
    Foramsulfuron (Standard)
  • HY-173058
    NtPPO-IN-1

    		Herbicide Protoporphyrinogen IX oxidase Others
    NtPPO-IN-1 (Compound A4) is the inhibitor for Nicotiana tabacum PPO (NtPPO) with a Ki of 9.05 nM. NtPPO-IN-1 exhibits herbicidal activity against Setaria viridis, Echinochloa crus-galli, Digitaria sanguinalis, Amaranthus retroflexus, Abutilon theophrasti and Portulaca oleracea, and exhibits 30-50% injury to corn and rice (150 g a.i./ha) .
    NtPPO-IN-1
  • HY-B0863
    Glyphosate

    		Apoptosis Autophagy Necroptosis Neurological Disease
    Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .
    Glyphosate
  • HY-163570
    PPO-IN-11

    		Protoporphyrinogen IX oxidase Others
    PPO-IN-11 (Compound 10bh) is an inhibitor for protoporphyrinogen IX oxidase (PPO), that inhibits nicotiana tabacum PPO (NtPPO) with Ki of 0.0603 μM. PPO-IN-11 exhibits herbicidal activities against dicot weeds Leaf mustard, Chickweed, Chenopodium serotinum and monocot weeds Alopecurus aequalis, Poa annua, and Polypogon fugax with a dose of 150 g a.i./ha .
    PPO-IN-11
  • HY-B1869R
    Metsulfuron-methyl (Standard)

    		Herbicide Others
    Metsulfuron-methyl (Standard) is the analytical standard of Metsulfuron-methyl. This product is intended for research and analytical applications. Metsulfuron-methyl is a systemic sulfonylurea herbicide that has been widely used to control broadleaf weeds and annual grasses in rice, corn, wheat, and barley. Metsulfuron-methyl exhibits high herbicidal activity and low mammalian toxicity, with an LD50 for rats exceeding 5000 mg/kg .
    Metsulfuron-methyl (Standard)
  • HY-B0863B
    Glyphosate isopropylammonium

    		Apoptosis Autophagy Necroptosis Neurological Disease
    Glyphosate isopropylammonium, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate isopropylammonium inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate isopropylammonium induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .
    Glyphosate isopropylammonium
  • HY-170920
    Herbicide safener-4

    		Cytochrome P450 SOD Glutathione S-transferase Acetolactate Synthase (ALS) Others
    Herbicide safener-4 (Compound I-15) is a Herbicide safener, improving the herbicide resistance of crops without reducing the herbicidal effect on targeted weed species. Herbicide safener-4 competitively binds to the ALS active site with Mesosulfuron-methyl (HY-126987). Herbicide safener-4 enhances GSH (HY-D0187), GST, CYP450, POD, SOD and ALS activity in plants .
    Herbicide safener-4
  • HY-151095
    Phytoene desaturase-IN-1

    		Reactive Oxygen Species Others
    Phytoene desaturase-IN-1 is a potent phytoene desaturase (PDS) inhibitor (Kd: 65.9 μM) through π−π stacking effect with Phe301 residue. Phytoene desaturase-IN-1 shows broad spectrum of postemergence herbicidal activity. Phytoene desaturase-IN-1 induces PDS mRNA reduction, phytoene and reactive oxygen species (ROS) accumulation in albino leaves. Phytoene desaturase-IN-1 can be used in the area of agricultural production .
    Phytoene desaturase-IN-1
  • HY-172151
    PPO-IN-17

    		Herbicide Protoporphyrinogen IX oxidase Others
    PPO-IN-17 (Compound 6R) is the inhibitor protoporphyrinogen IX oxidase (PPO) that inhibits Nicotiana tobacco PPO (NtPPO) with Ki of 30.34 nM. PPO-IN-17 exhibits herbicidal activity that inhibits barnyardgrass (E. crus-galli), foxtail grass (D. sanguinalis), alfalfa (M. sativa) and Canada cocklebur (C. canadensis) (>95% inhibition rate at a concentration of 37.5 g/hm 2). PPO-IN-17 exhibits no toxicity on rice (at a concentration of 75 g/hm 2) or on honeybees (at a concentration of 6400 mg/kg) .
    PPO-IN-17

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