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Results for "

hexapeptide

" in MedChemExpress (MCE) Product Catalog:

34

Inhibitors & Agonists

1

Biochemical Assay Reagents

40

Peptides

3

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P3163
    Hexapeptide-9

    		Biochemical Assay Reagents Others
    Hexapeptide-9 is a collagen peptide, with anti-aging activity. Hexapeptide-9 is commonly used as the ingredient in skin care products for improving the appearance of the skin .
    Hexapeptide-9
  • HY-P2096
    Hexapeptide-11

    		Reactive Oxygen Species ATM/ATR MDM-2/p53 Infection
    Hexapeptide-11 is a bioactive peptide with anti-aging effect. Hexapeptide-11 protects fibroblasts against oxidative stress-mediated premature cellular senescence by mediating a downregulation of cellular proteins, such as ataxia telangiectasia mutated (ATM) and p53 .
    Hexapeptide-11
  • HY-P5225
    Acetyl hexapeptide-38

    		PGC-1α Others
    Acetyl hexapeptide-38 is a bioactive peptide with upregulate adipogenesis effect and has been reported used as a cosmetic ingredient .
    Acetyl hexapeptide-38
  • HY-P0033
    Argireline

    Acetyl hexapeptide-3

    		 Calcium Channel Neurological Disease
    Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity .
    Argireline
  • HY-N6793
    Phomopsin A

    		Microtubule/Tubulin Cancer
    Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis. Phomopsin A is a noncompetitive inhibitor of the binding of radiolabeled vincristine to tubulin .
    Phomopsin A
  • HY-125553
    Hexapeptide-10

    Serilesine

    		 Amino Acid Derivatives Others
    Hexapeptide-10 is an amino acid derivative .
    Hexapeptide-10
  • HY-P5227
    Acetyl hexapeptide-49

    		Interleukin Related Inflammation/Immunology
    Acetyl hexapeptide-49 (example 13) is a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient. Acetyl hexapeptide-49 can alleviate stimulation of mammalian skin cells and protect cell vitality .
    Acetyl hexapeptide-49
  • HY-P0033A
    Argireline acetate

    Acetyl hexapeptide-3 acetate

    		 Calcium Channel Neurological Disease
    Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity .
    Argireline acetate
  • HY-N10793
    RA-XI

    		Others Cancer
    RA-XI is a bicyclic hexapeptide isolated from Rubia cordifolia with antitumour activity .
    RA-XI
  • HY-P10175
    Acetalin-1

    		Opioid Receptor Neurological Disease
    Acetalin-1 (Ac-RFMWMK-NH2), a hexapeptide, is a μ opioid receptor antagonist with high affinity for μ and κ3 opioid receptor, weak affinity for κ1 receptors and no affinity for κ2 receptors .
    Acetalin-1
  • HY-P1313A
    PAR 4 (1-6) (TFA)

    GYPGQV TFA

    		 Protease Activated Receptor (PAR) Others
    PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist .
    PAR 4 (1-6) (TFA)
  • HY-19738
    NQTrp

    		Tau Protein Neurological Disease
    NQTrp, an aromatic naphthoquinone-tryptophan hybrid molecule, an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects. NQTrp inhibits the in vitro aggregation of hexapeptide ( 41GCWMLY 46 within the N-terminus of γD-crystallin) as well as full-length γD-crystallin .
    NQTrp
  • HY-N10790
    RA-V

    		Wnt c-Myc Notch Cancer
    RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways .
    RA-V
  • HY-P2673
    Lys-Arg-Thr-Leu-Arg-Arg

    KRTLRR

    		 EGFR Others
    Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C .
    Lys-Arg-Thr-Leu-Arg-Arg
  • HY-P2333
    LCKLSL
    5 Publications Verification

    		 Annexin A Cardiovascular Disease
    LCKLSL is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. LCKLSL also inhibits the generation of plasmin and has anti-angiogenic roles .
    LCKLSL
  • HY-P2333A
    LCKLSL hydrochloride
    5 Publications Verification

    		 Annexin A Cardiovascular Disease
    LCKLSL hydrochloride is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL hydrochloride potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. LCKLSL hydrochloride also inhibits the generation of plasmin and has anti-angiogenic roles .
    LCKLSL hydrochloride
  • HY-120301
    L-366682

    		Oxytocin Receptor Endocrinology
    L-366682, a cyclic hexapeptide, possesses antagonism of oxytocin .
    L-366682
  • HY-P1675A
    Acetyl-PHF6 amide TFA
    1 Publications Verification

    AcPHF6 TFA; Ac-VQIVYK-NH2 TFA

    		 Tau Protein Neurological Disease
    Acetyl-PHF6 amide TFA (AcPHF6 TFA) is a tau derived hexapeptide.
    Acetyl-PHF6 amide TFA
  • HY-125567
    Antileukinate

    		CXCR Inflammation/Immunology
    Antileukinate, a hexapeptide, is a potent inhibitor of CXC-chemokine receptor (CXCR). Antileukinate inhibits neutrophil chemotaxis and activation. Antileukinate can be used for the research of acute inflammation and injury .
    Antileukinate
  • HY-P10151
    PD 156252

    		Endothelin Receptor Cardiovascular Disease
    PD 156252 is a hexapeptide that is a highly potent endothelin (ET) antagonist. PD 156252 has enhanced binding affinity for rabbit ETA and rat ETB receptor subtypes with IC50 values of 1.0 and 40 nM, respectively.
    PD 156252
  • HY-P1313
    PAR 4 (1-6) (human)

    GYPGQV

    		 Protease Activated Receptor (PAR) Others
    PAR 4 (1-6) human, a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist .
    PAR 4 (1-6) (human)
  • HY-P3119
    Desotamide

    Desotamide A

    		 Bacterial Infection
    Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).
    Desotamide
  • HY-P10673
    KwFwLL-NH2

    		GHSR Metabolic Disease
    KwFwLL-NH2, a hexapeptide, is a ghrelin receptor ligand. KwFwLL-NH2 can act as a specific inverse agonist at the ghrelin receptor but with moderate potency (EC50=45.6 nM) .
    KwFwLL-NH2
  • HY-P2673A
    Lys-Arg-Thr-Leu-Arg-Arg acetate

    KRTLRR acetate

    		 Fluorescent Dye EGFR Cancer
    Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) acetate is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg acetate is a substrate of EGF receptor protein kinase C and can be used to measure protein kinase C activity .
    Lys-Arg-Thr-Leu-Arg-Arg acetate
  • HY-P2054
    Mvt-101

    		HIV Protease Infection
    Mvt-101 is a hexapeptide-based inhibitor of HIV-1 protease. Mvt-101 is also reduced-peptide-bond inhibitor. Mvt-101 inhibits reproduction of the HIV virus by blocking protease action .
    Mvt-101
  • HY-P4788
    Acetyl-Amyloid β-Protein (1-6) amide

    		Amyloid-β Neurological Disease
    Acetyl-Amyloid β-Protein (1-6) amide is a hexapeptide that contains a potential copper(II) binding site. Acetyl-Amyloid β-Protein (1-6) amide can be used for research of Alzheimer's disease and related disorders .
    Acetyl-Amyloid β-Protein (1-6) amide
  • HY-P10177
    Acetalin-3

    		Opioid Receptor Neurological Disease
    Acetalin-3 (Ac-RFMWMT-NH2), a hexapeptide, is a μ opioid receptor antagonist with high affinity for μ and κ3 opioid receptor, weak affinity for κ1 receptors and no affinity for κ2 receptors .
    Acetalin-3
  • HY-P4651
    H-Tyr-Ile-Gly-Ser-Arg-NH2

    		TGF-β Receptor Others
    H-Tyr-Ile-Gly-Ser-Arg-NH2 is a hexapeptide that is an essential fragment of laminin responsible for efficient cell adhesion and receptor binding. H-Tyr-Ile-Gly-Ser-Arg-NH2 promotes various epithelial cell adhesion activities .
    H-Tyr-Ile-Gly-Ser-Arg-NH2
  • HY-P4910
    Baceridin

    		Proteasome Apoptosis Cancer
    Baceridin is a proteasome inhibitor and a cyclic hexapeptide. Baceridin can be isolated from the culture medium of Epiphytic Bacillus. Baceridin can inhibit cell cycle progression and induce tumor cell apoptosis through a p53-independent pathway. Baceridin can be used in cancer research .
    Baceridin
  • HY-E70375
    Fructosyl-peptide oxidase (FPOX-CE)

    Fructosyl-peptide: oxygen oxidoreductase

    		 Others Others
    Fructosyl-peptide oxidase (FPOX-CE) (Fructosyl-peptide: oxygen oxidoreductase) is an enzyme that catalyzes the oxidation of glycopeptides. Fructosyl-peptide oxidase (FPOX-CE) shows high activity against small molecule glycated peptides, but no activity is detected against the glycated hexapeptide standard fVHLTPE used in the study. Fructosyl-peptide oxidase (FPOX-CE) can be used in the study of diabetes monitoring .
    Fructosyl-peptide oxidase (FPOX-CE)
  • HY-P5506
    C5a Receptor agonist, W5Cha

    		Complement System Others
    C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC50=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor .
    C5a Receptor agonist, W5Cha
  • HY-P10281
    RW3

    		Bacterial Infection
    RW3 is a small cationic hexapeptide with amphiphilic properties. RW3 targets the plasma membrane of bacteria and works by inhibiting cell respiration and cell wall synthesis. RW3 shows high biological activity against gram-positive bacteria and does not show significant cytotoxic or hemolytic effects in previous studies. RW3 quickly kills 97% of the initial colony forming units (CFU) within 10 minutes at twice the minimum inhibitory concentration (MIC). RW3 can be used in antimicrobial and antifungal studies .
    RW3
  • HY-P1121
    WKYMVM-NH2

    		Formyl Peptide Receptor (FPR) Inflammation/Immunology
    WKYMVM-NH2 is a hexapeptide that activates neutrophils and myeloid cells via the FPRL1 and FPRL2 receptors. It exhibits EC50 values of 2 nM and 80 nM in HL-60-FPRL1 and HL-60-FPRL2 cells, respectively. In HL-60 cells stably expressing FPRL2, WKYMVM-NH₂ induces chemotaxis, with optimal migration observed at concentrations ranging from 10 to 50 nM. It also stimulates superoxide production in neutrophils, with an EC50 of 75 nM. WKYMVM-NH₂ is a useful tool for research in the field of inflammatory diseases .
    WKYMVM-NH2
  • HY-P2823
    Trypsinogen

    		Endogenous Metabolite Biochemical Assay Reagents Others
    Trypsinogen, a proenzyme synthesized in the pancreas, is activated to form trypsin by enterokinase upon reaching the small intestine lumen, where it opens a hexapeptide bond at the Lys6 - Ile7 junction, leading to the production of the active enzyme. This single polypeptide chain, composed of 229 amino acids and stabilized by six disulfide bridges, further autocatalytically converts additional trypsinogen into trypsin, which is initially present as β-trypsin before undergoing autolysis at the Lys131 - Ser132 site to form α-trypsin. As a serine protease, trypsin features His46 and Ser183 at its active site and exhibits optimal enzymatic activity at a pH range of 7 to 9.
    Trypsinogen

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