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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

human IgG2 antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) Antibody-Drug Conjugates (ADCs) (1) Anaplastic lymphoma kinase (ALK) (1) Apoptosis (2) CD22 (1) CD3 (1) EGFR (3) GCGR (1) IGF-1R (1) Integrin (1) Interleukin Related (4) Microtubule/Tubulin (1) Notch (1) TGF-beta/Smad (1) Thrombin (1) TNF Receptor (1) Wnt (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (1) Inflammation/Immunology (14) Metabolic Disease (1) Neurological Disease (2)

Inhibitors & Agonists

MCE Kits

Inhibitory Antibodies

Natural
Products

Antibodies

Targets Recommended: ADC Antibody Antibody-Drug Conjugates (ADCs) ADC Linker PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99041

Panitumumab 1 Publications Verification ABX-EGF	EGFR	Cancer
Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer .

HY-P99041A

Panitumumab (anti-EGFR)	EGFR	Cancer
Panitumumab (anti-EGFR) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (anti-EGFR) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (anti-EGFR) can be used in the research of cancers, such as colon cancer .

HY-P9974

Vantictumab OMP-18R5	Wnt	Cancer
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma .

HY-P99909

Elranatamab PF-06863135	TNF Receptor	Inflammation/Immunology
Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P99320

Tarextumab OMP 59R5; Anti-human NOTCH2 Recombinant antibody	Notch	Cancer
Tarextumab (OMP-59R5) is an anti-Notch2/3 fully human IgG2 monoclonal antibody. Tarextumab shows anti-tumor activity .

HY-P9925

Brodalumab 2 Publications Verification AMG 827; KHK4827	Interleukin Related	Inflammation/Immunology
Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis .

HY-P99332

Visilizumab Anti-human CD3E Recombinant antibody; HuM291	Apoptosis	Inflammation/Immunology Cancer
Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research .

HY-P99485

Brazikumab AMG 139; MEDI2070	Interleukin Related	Inflammation/Immunology
Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23, with a K_D of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease .

HY-P990713

Nolavetbart	Interleukin Related	Inflammation/Immunology
Nolavetbart is an anti-Canlupfam IL31RA human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P99465

Befovacimab BAY 1093884	Thrombin	Cardiovascular Disease
Befovacimab (BAY 1093884) is a fully human monoclonal IgG2 antibody able to bind to tissue factor pathway inhibitor (TFPI). Befovacimab can be used for haemophilia A/B research .

HY-P99353

Ascrinvacumab 2 Publications Verification Anti-ACVRL1 / ALK-1 Reference antibody (ascrinvacumab); PF-03446962	Anaplastic lymphoma kinase (ALK)	Cancer
Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a K_d value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC) .

HY-P99205

Glembatumumab	ADC Antibody	Cancer
Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling (ADC) with antitumor activity .

HY-P99444

Astegolimab 1 Publications Verification MSTT 1041A; RG 6149	Interleukin Related	Inflammation/Immunology
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research .

HY-141604

Glembatumumab vedotin CDX-011; CR011-vcMMAE	Antibody-Drug Conjugates (ADCs) Microtubule/Tubulin	Cancer
Glembatumumab vedotin (CDX-011) is an ADC (antibody-drug conjugates (ADCs)) comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects .

HY-P99268

Seribantumab SAR 256212; MM 121; Anti-human ERBB3/ErbB 3 Recombinant antibody	EGFR Apoptosis	Cancer
Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models .

HY-P9954

Catumaxomab	CD3	Cancer
Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers .

HY-P99867

Dusigitumab MEDI 573	IGF-1R	Others
Dusigitumab (MEDI 573) is a human IgG2λ monoclonal antibody that specifically targets IGF2 and IGF1 .

HY-P990013

Gulgafafusp alfa	GCGR	Metabolic Disease
Gulgafafusp alfa is a human IgG2κ antibody targeting the glucagon-like peptide 1 receptor GLP1R .

HY-P990009

Nisevokitug NIS-793	TGF-beta/Smad	Cancer
Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β (TGFB1/TGFB2). Nisevokitug is expressed by CHO-K1 cells .

HY-P99336

Enlimomab BI-RR 0001; Anti-human IL6 Recombinant antibody	Integrin	Neurological Disease Inflammation/Immunology
Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research .

HY-P99464

Bectumomab IMMU-LL 2	CD22	Cancer
Bectumomab (IMMU-LL 2) is an humanized IgG2a mAb against human CD22 (antigen). Bectumomab is also an anti-lymphoma antibody fragment. Bectumomab can be used for imaging in combination with technetium 99 (Tc99m LL2 Fab). Moreover, Bectumomab examines in the staging of recurrent or newly diagnosed non-Hodgkin's lymphoma (NHL) and to assess targeting before radioimmunoresearch (RIT) .

Cat. No.	Product Name

HY-K0214

Protein G Agarose 2 Publications Verification
MCE Protein G Agarose, a 4% highly cross-linked agarose reagent coupled with recombinant Protein G, effectively purifies mammalian monoclonal and polyclonal antibodies, such as human IgG3 and rat IgG2a.

Cat. No.	Product Name	Target	Research Area

HY-P99460

Bapotulimab BAY-1905254	Inhibitory Antibodies	Inflammation/Immunology Cancer
Bapotulimab (BAY-1905254) is a fully human IgG2 antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2). Bapotulimab has antitumor and immunosuppressive effects .

HY-P99041

Panitumumab 1 Publications Verification ABX-EGF	EGFR	Cancer
Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer .

HY-P99041A

Panitumumab (anti-EGFR)	EGFR	Cancer
Panitumumab (anti-EGFR) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (anti-EGFR) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (anti-EGFR) can be used in the research of cancers, such as colon cancer .

HY-P9974

Vantictumab OMP-18R5	Wnt	Cancer
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma .

HY-P99002

Human IgG2 kappa, Isotype Control	Inhibitory Antibodies	Inflammation/Immunology
Human IgG2 kappa, Isotype Control, a human-mouse chimeric monoclonal antibody, is an isotype control for human IgG2κ antibody.

HY-P99200

Fulranumab	Inhibitory Antibodies	Neurological Disease
Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor (NGF) and can be used for the research of pain .

HY-P990732

Cepeprubart	Inhibitory Antibodies	Inflammation/Immunology
Cepeprubart is an anti-SELPLG human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990712

Ersodetug	Inhibitory Antibodies	Inflammation/Immunology
Ersodetug is an anti-INSR (insulin receptor) human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990713

Nolavetbart	Interleukin Related	Inflammation/Immunology
Nolavetbart is an anti-Canlupfam IL31RA human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990753

Omoprubart	Inhibitory Antibodies	Inflammation/Immunology
Omoprubart is an anti-C5 human?IgG2-G4 κ monoclonal antibody .

HY-P99465

Befovacimab BAY 1093884	Thrombin	Cardiovascular Disease
Befovacimab (BAY 1093884) is a fully human monoclonal IgG2 antibody able to bind to tissue factor pathway inhibitor (TFPI). Befovacimab can be used for haemophilia A/B research .

HY-P99909

Elranatamab PF-06863135	TNF Receptor	Inflammation/Immunology
Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P99320

Tarextumab OMP 59R5; Anti-human NOTCH2 Recombinant antibody	Notch	Cancer
Tarextumab (OMP-59R5) is an anti-Notch2/3 fully human IgG2 monoclonal antibody. Tarextumab shows anti-tumor activity .

HY-P9925

Brodalumab 2 Publications Verification AMG 827; KHK4827	Interleukin Related	Inflammation/Immunology
Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis .

HY-P99332

Visilizumab Anti-human CD3E Recombinant antibody; HuM291	Apoptosis	Inflammation/Immunology Cancer
Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research .

HY-P99411

Ontamalimab SHP647	Inhibitory Antibodies	Inflammation/Immunology
Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Ontamalimab can be used for the research of Crohn's disease .

HY-P99485

Brazikumab AMG 139; MEDI2070	Interleukin Related	Inflammation/Immunology
Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23, with a K_D of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease .

HY-P99353

Ascrinvacumab 2 Publications Verification Anti-ACVRL1 / ALK-1 Reference antibody (ascrinvacumab); PF-03446962	Anaplastic lymphoma kinase (ALK)	Cancer
Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a K_d value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC) .

HY-P99205

Glembatumumab	ADC Antibody	Cancer
Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling (ADC) with antitumor activity .

HY-P99444

Astegolimab 1 Publications Verification MSTT 1041A; RG 6149	Interleukin Related	Inflammation/Immunology
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research .

HY-P99268

Seribantumab SAR 256212; MM 121; Anti-human ERBB3/ErbB 3 Recombinant antibody	EGFR Apoptosis	Cancer
Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models .

HY-P9954

Catumaxomab	CD3	Cancer
Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers .

HY-P990864

Anti-CD3 Antibody (OKT-3)	Inhibitory Antibodies	Others
Anti-CD3 Antibody (OKT-3) is a kind of mouse IgG2a,?κ chimeric antibody, targeting to human CD3. The recommend isotype control of Anti-CD3 Antibody (OKT-3): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990832

Anti-MHC Class I Antibody (W6/32)	Inhibitory Antibodies	Others
Anti-MHC Class I Antibody (W6/32) is a kind of mouse IgG2a,?κ chimeric antibody, targeting to human MHC Class I. The recommend isotype control of Anti-MHC Class I Antibody (W6/32): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990861

Anti-CD4 Antibody (OKT-4)	Inhibitory Antibodies	Others
Anti-CD4 Antibody (OKT-4) is a kind of mouse IgG2b,?κ chimeric antibody, targeting to human CD4. The recommend isotype control of Anti-CD4 Antibody (OKT-4): Mouse IgG2b kappa, Isotype Control (HY-P99982).

HY-P990805

Anti-Human/Mouse GRP78 Antibody (C38)	Inhibitory Antibodies	Others
Anti-Human/Mouse GRP78 Antibody (C38) is a kind of mouse IgG2b kappa in vivo mouse antibody, targeting to GRP78. The recommend isotype control of Anti-Human/Mouse GRP78 Antibody (C38): Mouse IgG2b kappa, Isotype Control (HY-P99982).

HY-P990847

Anti-E-Selectin Antibody (CL2)	Inhibitory Antibodies	Others
Anti-E-Selectin Antibody (CL2) is a kind of mouse IgG2a, κ chimeric antibody, targeting to human E-Selectin. The recommend isotype control of Anti-E-Selectin Antibody (CL2): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990149

Anti-Mouse/Human TYRP1 Antibody (TA99)	Inhibitory Antibodies	Others
Anti-Mouse/Human TYRP1 Antibody (TA99) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse/human TYRP1.

HY-P990865

Anti-CD28 Antibody (9.3)	Inhibitory Antibodies	Others
Anti-CD28 Antibody (9.3) is a kind of mouse IgG2a chimeric antibody, targeting to human CD28. The recommend isotype control of Anti-CD28 Antibody (9.3): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990167

Anti-Mouse/Human PrP/prion protein Antibody (TW1)	Inhibitory Antibodies	Others
Anti-Mouse/Human PrP/prion protein Antibody (TW1) is a mouse-derived IgG2a type antibody inhibitor, targeting to mouse/human PrP/prion protein.

HY-P990238

Anti-Human/Rat HER2 (neu) Antibody (7.16.4)	Inhibitory Antibodies	Others
Anti-Human/Rat HER2 (neu) Antibody (7.16.4) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to human/rat HER2.

HY-P990210

Anti-Mouse/Human IL-7 Antibody (M25)	Inhibitory Antibodies	Others
Anti-Mouse/Human IL-7 Antibody (M25) is a mouse-derived IgG2b type antibody inhibitor, targeting to mouse/human IL-7.

HY-P990138

Anti-Monkey/Human CD20 Antibody (2H7)	Inhibitory Antibodies	Others
Anti-Monkey/Human CD20 Antibody (2H7) is a mouse-derived IgG2b, κ type antibody inhibitor, targeting to monkey/human CD20.

HY-P990845

Anti-Ganglioside GD2 Antibody (14G2a)	Inhibitory Antibodies	Others
Anti-Ganglioside GD2 Antibody (14G2a) is a kind of mouse IgG2a, κ chimeric antibody, targeting to human Ganglioside GD2. The recommend isotype control of Anti-Ganglioside GD2 Antibody (14G2a): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990846

Anti-Fy3 Antibody (MIMA-29)	Inhibitory Antibodies	Others
Anti-Fy3 Antibody (MIMA-29) is a kind of mouse IgG2a, κ chimeric antibody, targeting to human Fy3. The recommend isotype control of Anti-Fy3 Antibody (MIMA-29): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990859

Anti-CD44 Antibody (Hermes-1)	Inhibitory Antibodies	Others
Anti-CD44 Antibody (Hermes-1) is a kind of rat IgG2a, κ chimeric antibody, targeting to human CD44. The recommend isotype control of Anti-CD44 Antibody (Hermes-1): Rat IgG2a kappa, Isotype Control (HY-P990679).

HY-P990836

Anti-IL-9 Antibody (MH9A4)	Inhibitory Antibodies	Others
Anti-IL-9 Antibody (MH9A4) is a kind of mouse IgG2b, κ chimeric antibody, targeting to human IL-9. The recommend isotype control of Anti-IL-9 Antibody (MH9A4): Mouse IgG2b kappa, Isotype Control (HY-P99982).

HY-P990868

Anti-CD2 Antibody (CB.219)	Inhibitory Antibodies	Others
Anti-CD2 Antibody (CB.219) is a kind of mouse IgG2b, κ chimeric antibody, targeting to human CD2. The recommend isotype control of Anti-CD2 Antibody (CB.219): Mouse IgG2b kappa, Isotype Control (HY-P99982).

HY-P990189

Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243)	Inhibitory Antibodies	Others
Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to monkey/human MHC class II.

HY-P990207

Anti-Mouse/Human Integrin β7 Antibody (FIB504)	Inhibitory Antibodies	Others
Anti-Mouse/Human Integrin β7 Antibody (FIB504) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse/human Integrin β7.

HY-P990855

Anti-CD8α Antibody (OKT-8)	Inhibitory Antibodies	Others
Anti-CD8α Antibody (OKT-8) is a kind of mouse IgG2a chimeric antibody, targeting to human CD8α. The recommend isotype control of Anti-CD8α Antibody (OKT-8): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990146

Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238)	Inhibitory Antibodies	Others
Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse/rat/human v-H-Ras.

HY-P990851

Anti-c-Kit/CD117 Antibody (SR-1)	Inhibitory Antibodies	Others
Anti-c-Kit/CD117 Antibody (SR-1) is a kind of mouse IgG2a, κ chimeric antibody, targeting to human c-Kit/CD117. The recommend isotype control of Anti-c-Kit/CD117 Antibody (SR-1): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P99867

Dusigitumab MEDI 573	IGF-1R	Others
Dusigitumab (MEDI 573) is a human IgG2λ monoclonal antibody that specifically targets IGF2 and IGF1 .

HY-P990013

Gulgafafusp alfa	GCGR	Metabolic Disease
Gulgafafusp alfa is a human IgG2κ antibody targeting the glucagon-like peptide 1 receptor GLP1R .

HY-P990848

Anti-CTLA-4/CD152 Antibody (BN13)	Inhibitory Antibodies	Others
Anti-CTLA-4/CD152 Antibody (BN13) is a kind of mouse IgG2a, κ chimeric antibody, targeting to human CTLA-4/CD152. The recommend isotype control of Anti-CTLA-4/CD152 Antibody (BN13): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990863

Anti-CD32/FcγRIIA Antibody (IV.3)	Inhibitory Antibodies	Others
Anti-CD32/FcγRIIA Antibody (IV.3) is a kind of mouse IgG2b chimeric antibody, targeting to human CD32/FcγRIIA. The recommend isotype control of Anti-CD32/FcγRIIA Antibody (IV.3): Mouse IgG2b kappa, Isotype Control (HY-P99982).

HY-P990133

Anti-Monkey/Human CD40L/CD154 Antibody (5C8)	Inhibitory Antibodies	Others
Anti-Monkey/Human CD40L/CD154 Antibody (5C8) is a mouse-derived IgG2a type antibody inhibitor, targeting to monkey/human CD40L/CD154.

HY-P990196

Anti-Monkey/Human MDR-1/CD243 Antibody (UIC2)	Inhibitory Antibodies	Others
Anti-Monkey/Human MDR-1/CD243 Antibody (UIC2) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to monkey/human MDR-1/CD243.

HY-P990198

Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166)	Inhibitory Antibodies	Others
Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse/human Mac-2/Galectin-3.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P99460

Bapotulimab BAY-1905254	Classification of Application Fields Disease Research Fields Cancer	Others
Bapotulimab (BAY-1905254) is a fully human IgG2 antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2). Bapotulimab has antitumor and immunosuppressive effects .

HY-P99041

Panitumumab 1 Publications Verification ABX-EGF	Classification of Application Fields Disease Research Fields Cancer	EGFR
Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer .

HY-P99041A

Panitumumab (anti-EGFR)	Classification of Application Fields Disease Research Fields Cancer	EGFR
Panitumumab (anti-EGFR) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (anti-EGFR) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (anti-EGFR) can be used in the research of cancers, such as colon cancer .

HY-P9974

Vantictumab OMP-18R5	Classification of Application Fields Disease Research Fields Cancer	Wnt
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma .

HY-P99332

Visilizumab Anti-human CD3E Recombinant antibody; HuM291	Classification of Application Fields Disease Research Fields Cancer	Apoptosis
Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research .

HY-P99353

Ascrinvacumab 2 Publications Verification Anti-ACVRL1 / ALK-1 Reference antibody (ascrinvacumab); PF-03446962	Classification of Application Fields Disease Research Fields Cancer	Anaplastic lymphoma kinase (ALK)
Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a K_d value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC) .

HY-P99205

Glembatumumab	Classification of Application Fields Disease Research Fields Cancer	ADC Antibody
Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling (ADC) with antitumor activity .

HY-P99268

Seribantumab SAR 256212; MM 121; Anti-human ERBB3/ErbB 3 Recombinant antibody	Classification of Application Fields Disease Research Fields Cancer	EGFR Apoptosis
Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models .

HY-P9954

Catumaxomab	Classification of Application Fields Disease Research Fields Cancer	CD3
Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82451

	Human IgG2 Antibody (YA2196) IGHG2; immunoglobulin Gm2; immunoglobulin heavy constant gamma 2 (G2m marker)	WB, IHC-P, ICC/IF	Human
	Human IgG2 Antibody (YA2196) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2196), targeting Human IgG2, with a predicted molecular weight of 36 kDa (observed band size: 53 kDa). Human IgG2 Antibody (YA2196) can be used for WB, IHC-P, ICC/IF experiment in human background.

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human IgG2 antibody

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Antibodies

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