2. Search Result
Search Result
Results for "

hydrolytic

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

1

Fluorescent Dye

8

Biochemical Assay Reagents

5

Peptides

5

Natural
Products

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-129217
    Naringinase

    		Glycosidase Others
    Naringinase, a hydrolytic enzymatic complex, possesses the activity of both α-L-rhamnosidase and β-D-glucosidase. Naringinase has wide occurrence in nature. Naringinase can be used in the biotransformation of steroids, antibiotics, and mainly on glycosides hydrolysis .
    Naringinase
  • HY-N10418
    Isorhapontin

    		Fungal Infection
    Isorhapontin is an antifungal agent. Isorhapontin inhibits the hydrolytic activity of Trichoderma cellobiohydrolase I (CBH I) with a Ki of 57.2 μM. Isorhapontin also inhibits the activity of Trichoderma endoglucanase I .
    Isorhapontin
  • HY-131824
    5,6-DM-cBIMP

    		Phosphodiesterase (PDE) Others
    5,6-DM-cBIMP, a cyclic nucleotide analog, is an agonist of PDE2 that can significantly enhance the cAMP and cGMP hydrolytic activities of PDE2 [2.
    5,6-DM-cBIMP
  • HY-131823
    5,6-DCl-cBIMP

    		Phosphodiesterase (PDE) Others
    5,6-DCl-cBIMP, a cyclic adenosine monophosphate analog, can act as an agonist of PDE2 and significantly enhance the cAMP and cGMP hydrolytic activities of PDE2 .
    5,6-DCl-cBIMP
  • HY-135886
    2-Nitrophenyl α-D-galactopyranoside

    		Biochemical Assay Reagents Others
    2-Nitrophenyl α-D-galactopyranoside, a nitrophenyl derivative, is a substrate to test for hydrolytic activity of glycosyl hydrolase .
    2-Nitrophenyl α-D-galactopyranoside
  • HY-W354821
    4-Methylumbelliferyl Decanoate

    4-MUD

    		 Fluorescent Dye Metabolic Disease
    4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases .
    4-Methylumbelliferyl Decanoate
  • HY-138152
    Z-D-Arg-Gly-Arg-pNA dihydrochloride

    Benzyl-D-Arg-Gly-Arg-pNA dihydrochloride

    		 Fluorescent Dye Others
    Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate .
    Z-D-Arg-Gly-Arg-pNA dihydrochloride
  • HY-P4468
    Lys-Ala-pNA

    		Dipeptidyl Peptidase Others
    Lys-Ala-pNA is hydrolytic substrate the of dipeptidyl peptidase (DPP) II with Km of 0.42 mM .
    Lys-Ala-pNA
  • HY-W704138
    2-Hydroxy-atrazine

    		Endogenous Metabolite Drug Derivative Others
    2-Hydroxy-atrazine is a non-herbicidal primary photoproduct that results from the hydrolytic dechlorination of atrazine.
    2-Hydroxy-atrazine
  • HY-P10615
    Abz-YGGRASDQ-EDDnp

    		Fluorescent Dye Transthyretin (TTR) Others
    Abz-YGGRASDQ-EDDnp is a fluorescent substrate of transthyretin (TTR) protein and is used to detect the hydrolytic activity of TTR protein .
    Abz-YGGRASDQ-EDDnp
  • HY-163169
    Phenyl-glutarimide 4'-oxyacetic acid

    		Ligands for E3 Ligase Others
    Phenyl-glutarimide 4 ’-oxyacetic acid is a carboxylic acid-functionalized cerebellar ligand that can be used in the development of PROTAC deactivators. Phenyl-glutarimide 4 ’-oxyacetic acid binds to PROTAC has better hydrolytic stability and efficacy .
    Phenyl-glutarimide 4'-oxyacetic acid
  • HY-P2893B
    Creatinase, microorganism

    Creatine amidinohydrolase, microorganism

    		 Endogenous Metabolite Metabolic Disease
    Creatine amidinohydrolase, microorganism is a hydrolytic enzyme that catalyzes the hydrolysis of creatine into creatinine and urea, playing a crucial role in the measurement of creatinine concentration. Creatine amidinohydrolase, microorganism can be used in the development of biosensors for measuring serum creatinine levels .
    Creatinase, microorganism
  • HY-W704138R
    2-Hydroxy-atrazine (Standard)

    		Endogenous Metabolite Others
    2-Hydroxy-atrazine (Standard) is the analytical standard of 2-Hydroxy-atrazine. This product is intended for research and analytical applications. 2-Hydroxy-atrazine is a non-herbicidal primary photoproduct that results from the hydrolytic dechlorination of atrazine.
    2-Hydroxy-atrazine (Standard)
  • HY-116033
    BMS-363131

    		Ser/Thr Protease Inflammation/Immunology
    BMS-363131 is a selective inhibitor for tryptase, with an IC50 <1.7 nM. BMS-363131 is hydrolytic stable at pH=7 and pH=9. BMS-363131 attenuates the astham in a guinea pig model .
    BMS-363131
  • HY-131842
    6-Bn-cAMP

    N6-Benzyladenosine-3',5'-cyclic monophosphate

    		 PKA Cancer
    6-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinase (PKA) which does not activate Epac. 6-Bn-cAMP increases hydrolytic stability against PDE, esterases, amidases and considerably higher membrane permeability compared to cAMP .
    6-Bn-cAMP
  • HY-N7768
    β-Ergocryptine

    β-Ergokryptine

    		 Biochemical Assay Reagents 5-HT Receptor Cardiovascular Disease Endocrinology
    β-Ergocryptine (β-Ergokryptine) is a new Alkaloid of the Ergotoxine group. β-Ergocryptine can be isolated from ergot plants. β-Ergocryptine has adrenal hydrolytic activity, serotonin antagonism. β-Ergocryptine affects vascular tone .
    β-Ergocryptine
  • HY-12798C
    AR-13503

    AR-13324 M1 metabolite

    		 PKC ROCK Cardiovascular Disease
    AR-13503 (AR-13324 M1 metabolite) is the hydrolytic metabolite of AR-13324 mesylate. AR-13324 is a ROCK kinase and PKC inhibitor with anti-angiogenic and retinal health-improving effects, showing potential for use in retinal disease research .
    AR-13503
  • HY-134283
    8-Benzylthio-cAMP

    		PKA Apoptosis Others
    8-Benzylthio-cAMP is a derivative of cyclic adenosine monophosphate (cAMP). 8-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinases. Compared with cyclic adenosine monophosphate, it is more stable to phosphodiesterase (PDE) hydrolysis and has higher membrane permeability. 8-Bn-cAMP can be used to study the role of cAMP in regulating cell proliferation, differentiation and apoptosis .
    8-Benzylthio-cAMP
  • HY-E70413
    Amino acid arylamidase, hog kidney

    		Endogenous Metabolite Cardiovascular Disease Metabolic Disease
    Amino acid arylamidase, hog kidney is a metalloprotease that can hydrolyze proteins or peptides containing free α-amino or α-imino groups, playing a crucial role in amino acid metabolism and protein digestion. Its hydrolytic activity can be blocked by acetylation of the N-terminus. Amino acid arylamidase, hog kidney can be used in research on hepatic diseases, biliary diseases, and heart failure .
    Amino acid arylamidase, hog kidney
  • HY-P10668
    Ac-EVKKQR-pNA

    		Dengue Virus Flavivirus Infection
    Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
    Ac-EVKKQR-pNA
  • HY-12798E
    (R)-AR-13503

    (R)-AR-13324 M1 metabolite

    		 PKC ROCK Drug Metabolite Cardiovascular Disease
    (R)-AR-13503 ((R)-AR-13324 M1 metabolite) is the the (R)-enantiomer of AR-13503 (HY-12798C). AR-13503 is the hydrolytic metabolite of AR-13324 mesylate. AR-13324 is a ROCK kinase and PKC inhibitor with anti-angiogenic and retinal health-improving effects, showing potential for use in retinal disease research .
    (R)-AR-13503
  • HY-P10053
    sPLA2-IIA Inhibitor

    		Phospholipase Metabolic Disease
    sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids .
    sPLA2-IIA Inhibitor
  • HY-P2769A
    Thermostable β-Agarase

    		Biochemical Assay Reagents Others
    Thermostable β-Agarase is a hydrolase that can hydrolyze the β-1,4 linkages in agarose to produce neoagaro-oligosaccharides, and it can be used to extract DNA and RNA from gels. Compared to conventional β-Agarase, Thermostable β-Agarase exhibits higher heat resistance and stronger hydrolytic activity. The thermostable properties of Thermostable β-Agarase simplify experimental procedures and make it suitable for the rapid purification of intact large DNA molecules .
    Thermostable β-Agarase
  • HY-Y0850L
    Polyvinyl alcohol (Mw 85000-124000, 99+% hydrolyzed)

    PVA (Mw 85000-124000, 99+% hydrolyzed); Poly(Ethenol) (Mw 85000-124000, 99+% hydrolyzed)

    		 Biochemical Assay Reagents Others Cancer
    Polyvinyl alcohol (Mw 85000-124000, 99+% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 85000-124000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 85000-124000, 99+% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients .
    Polyvinyl alcohol (Mw 85000-124000, 99+% hydrolyzed)
  • HY-Y0850T
    Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed)-1

    PVA (Mw 146000-186000, 99+% hydrolyzed)-1; Poly(Ethenol) (Mw 146000-186000, 99+% hydrolyzed)-1

    		 Biochemical Assay Reagents Others Cancer
    Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 146000-186000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients .
    Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed)-1
  • HY-N1181
    Tamarixetin
    1 Publications Verification

    4'-O-Methyl Quercetin

    		 Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species Infection Cardiovascular Disease Inflammation/Immunology Cancer
    Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .
    Tamarixetin
  • HY-N1181R
    Tamarixetin (Standard)

    		Endogenous Metabolite ClpP Bacterial Apoptosis Akt Interleukin Related COX JNK p38 MAPK Reactive Oxygen Species Infection Cardiovascular Disease Inflammation/Immunology Cancer
    Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways .
    Tamarixetin (Standard)
  • HY-Y0850P
    Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed)

    PVA (Mw 146000-186000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 146000-186000, 87-89% hydrolyzed)

    		 Biochemical Assay Reagents Others Cancer
    Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 146000-186000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient .
    Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed)
  • HY-Y0850J
    Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed)

    PVA (Mw 13000-23000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 87-89% hydrolyzed)

    		 Biochemical Assay Reagents Others Cancer
    Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 130000-23000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient .
    Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed)
  • HY-W250795B
    Maltodextrin, dextrose equivalent 5.0-8.0

    		Endogenous Metabolite Others
    Maltodextrin, dextrose equivalent 5.0-8.0 can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs. Dextrose Equivalent (DE) expresses the number of reducing ends aldehyde groups relative to pure glucose at the same concentration, so that high DE indicates high hydrolytic conversion and lower average molecular mass .
    Maltodextrin, dextrose equivalent 5.0-8.0
  • HY-Y0850M
    Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed)

    PVA (Mw 85000-124000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 85000-124000, 87-89% hydrolyzed)

    		 Biochemical Assay Reagents Others Cancer
    Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 85000-124000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient .
    Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed)
  • HY-Y0850E
    Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)

    PVA (Mw 30000-70000, 87-90% hydrolyzed); Poly(Ethenol) (Mw 30000-70000, 87-90% hydrolyzed)

    		 Biochemical Assay Reagents Cardiovascular Disease Cancer
    Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients .
    Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: