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Results for "

ionizable cationic

" in MedChemExpress (MCE) Product Catalog:

42

Inhibitors & Agonists

16

Biochemical Assay Reagents

1

Isotope-Labeled Compounds

31

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145739
    ATX-0114

    		Liposome Others
    ATX-0114 is an ionizable cationic lipid .
    ATX-0114
  • HY-112251
    D-Lin-MC3-DMA
    Maximum Cited Publications
    71 Publications Verification

    		 Liposome Cancer
    D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
    D-Lin-MC3-DMA
  • HY-W590532
    306-O12B

    		Liposome Others
    306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
    306-O12B
  • HY-160553
    9322-O16B

    		Liposome Others
    9322-O16B, an ionizable cationic lipid, is used for LNP generation .
    9322-O16B
  • HY-W590548
    ATX-001

    		Liposome Others
    ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .
    ATX-001
  • HY-W598178
    93-O17O

    		Liposome Others
    93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
    93-O17O
  • HY-159709
    VL-422

    		Liposome Others
    VL-422 is an ionizable cationic lipid that can be used for lipid nanoparticle (LNP) and drug delivery research .
    VL-422
  • HY-W590681
    113-O12B

    		Liposome Others
    113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
    113-O12B
  • HY-W590679
    113-O16B

    		Liposome Others
    113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
    113-O16B
  • HY-145797
    L343

    		Liposome Others
    L343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics.
    L343
  • HY-112251A
    D-Lin-MC3-DMA (Excipient)

    		Liposome Cancer
    D-Lin-MC3-DMA Excipient, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
    D-Lin-MC3-DMA (Excipient)
  • HY-160908
    Lipid 88

    		Liposome Others
    Lipid 88 is an ionizable cationic lipid. Lipid 88 can be used to synthesize lipid nanoparticles and deliver mRNA .
    Lipid 88
  • HY-158796
    L202

    		Liposome Others
    L202 is an ionizable cationic lipid (pKa=6.04) that can be used for the study of mRNA and lipid nanoparticles .
    L202
  • HY-153372
    93-O17S

    		Liposome Others
    93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
    93-O17S
  • HY-159725
    BAmP-O16B

    		Liposome Others
    BAmP-O16B is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNPs) .
    BAmP-O16B
  • HY-112757
    DLinDMA
    1 Publications Verification

    		 Liposome Others
    DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
    DLinDMA
  • HY-159735
    Lipid 23

    		Liposome Others
    Lipid 23 is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNP). Lipid 23 can be used for mRNA delivery .
    Lipid 23
  • HY-139298
    L319

    Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate

    		 Liposome Inflammation/Immunology
    L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .
    L319
  • HY-W590531
    80-O16B

    		Biochemical Assay Reagents Liposome Others
    80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP) .
    80-O16B
  • HY-156985
    Lipid AX4

    		Isotope-Labeled Compounds Liposome Others
    Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89， and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .
    Lipid AX4
  • HY-159853
    C14-A1

    		Liposome Inflammation/Immunology
    C14-A1 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    C14-A1
  • HY-151511
    A12-Iso5-2DC18

    		Liposome Cancer
    A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
    A12-Iso5-2DC18
  • HY-159854
    C14-O2

    		Liposome Cancer
    C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    C14-O2
  • HY-149156
    Lipid C24

    		Liposome Cancer
    Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
    Lipid C24
  • HY-159726
    C10-200

    		Liposome Others
    C10-200 is an ionizable cationic lipid that can be used to generate lipid nanoparticles (LNPs). C10-200 is used in the study of mRNA delivery .
    C10-200
  • HY-142654
    ATX-002

    		Liposome Others
    ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
    ATX-002
  • HY-159859
    IZ-Chol

    		Liposome Others
    IZ-Chol (IZ-Cholesterol) is an ionizable cationic lipid containing cholesterol. IZ-Chol-LNPs is highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect .
    IZ-Chol
  • HY-W590678
    ssPalmO-Phe

    		Liposome Others
    SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.
    ssPalmO-Phe
  • HY-156936
    RCB-02-4-8

    		Liposome Others
    RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
    RCB-02-4-8
  • HY-159860
    IR-117-17

    		Liposome Others
    IR-117-17 is an ionizable cationic amino lipid, targeting the conducting airways. IR-117-17 could be degraded via esterase cleavage and thus be unlikely to accumulate upon repeated dosing .
    IR-117-17
  • HY-153737
    113-N16B

    		Liposome Others
    113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
    113-N16B
  • HY-W590683
    9A1P9

    		Liposome CRISPR/Cas9 Others
    9A1P9 is a multi-tail ionizable cationic phospholipid. 9A1P9 induces membrane destabilization. 9A1P9 can be used for CRISPR-Cas9 gene editing in mice .
    9A1P9
  • HY-159869
    G0-C14 analog

    		Liposome Others
    G0-C14 analog is a G0-C14 derivative. G0-C14 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) .
    G0-C14 analog
  • HY-151512
    A12-Iso5-4DC19

    		Liposome Inflammation/Immunology Cancer
    A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .
    A12-Iso5-4DC19
  • HY-160852
    YSK 12C4

    		Liposome Inflammation/Immunology
    YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND). YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines .
    YSK 12C4
  • HY-112251S
    D-Lin-MC3-DMA-13C3

    		Isotope-Labeled Compounds Others
    D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
    D-Lin-MC3-DMA-13C3
  • HY-W800849
    BP Lipid 315

    		Liposome Cancer
    BP Lipid 315 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. One of these esters features a symmetrical branched C17 tail, while the other is an asymmetric C11 tail.
    BP Lipid 315
  • HY-160552
    244cis

    		Liposome Others
    244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
    244cis
  • HY-145405
    C12-200
    5+ Cited Publications

    		 Liposome Others
    C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
    C12-200
  • HY-130751
    DODAP

    		Liposome Inflammation/Immunology
    DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
    DODAP
  • HY-159700
    AA3-DLin

    		Liposome Infection
    AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
    AA3-DLin
  • HY-157252
    CL4F8-6

    		Liposome Cancer
    CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
    CL4F8-6

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