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Results for "

lipid encapsulated

" in MedChemExpress (MCE) Product Catalog:

29

Inhibitors & Agonists

20

Biochemical Assay Reagents

1

Peptides

1

Click Chemistry

19

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130751
    DODAP

    		Liposome Inflammation/Immunology
    DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
    DODAP
  • HY-B0803
    Lumefantrine
    1 Publications Verification

    Benflumetol

    		 Parasite Infection
    Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity .
    Lumefantrine
  • HY-149167
    ATX-0126

    ATX 100

    		 Liposome Biochemical Assay Reagents Others
    ATX-0126 (Compound 2) is a Thiocarbamate-Based Ionizable Lipid. ATX-0126 can be used as an excipient in mRNA-encapsulating lipid nanoparticle .
    ATX-0126
  • HY-144004
    DSPE-PEG2000-Mal ammonium
    1 Publications Verification

    DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium

    		 Liposome Others
    DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
    DSPE-PEG2000-Mal ammonium
  • HY-143700
    18:0 DAP

    		Liposome Neurological Disease
    18:0 DAP can be used to formulate lipid nanoparticles (LNPs), which mRNA is encapsulated in their core .
    18:0 DAP
  • HY-W800778
    Bis(2-butyloctyl) 10-oxononadecanedioate

    		Liposome Cancer
    Bis(2-butyloctyl) 10-oxononadecanedioate is an ionizable lipid-like compound containing four hydrophobic tails bound by esters. It can be used to build lipids for mRNA encapsulation and delivery.
    Bis(2-butyloctyl) 10-oxononadecanedioate
  • HY-151508
    Diamino lipid DAL4

    		Liposome Cancer
    Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .
    Diamino lipid DAL4
  • HY-159711
    PPPDA-O16B

    		Liposome Cancer
    PPPDA-O16B is a lipid containing disulfide bonds used for DNA delivery. PPPDA-O16B can encapsulate DNA plasmid, releasing DNA selectively via lipid degradation catalyzed by GSH .
    PPPDA-O16B
  • HY-W800737
    BP Lipid 126

    		Liposome Cancer
    BP Lipid 126 is an amino ionizable lipid (Compound 143) from patent WO2017201333A1 with ester bonds located at C8 and C7 position relative to nitrogen. The ester linkages are introduced to improve tissue clearance. The ethanolamine head can effectively enhance mRNA encapsulation. BP Lipid 126 can be used in the generation of liposomes.
    BP Lipid 126
  • HY-W440787
    BP Lipid 142

    		Liposome Others
    BP Lipid 142 is derived from patent WO2018170306A1 (Example 102). BP Lipid 142 is an ionizable amine lipid analogous to SM-102. The propanolamine head improves encapsulation of mRNA. The lipid has both esters at C6 and C8 position relative to the amine nitrogen. Ester linkages in the lipid tails are introduced into the structure to improve tissue clearance. The primary ester located at C6 is attached with a long (11-carbon) lipid tail. The lipid can be used for mRNA-based therapies.
    BP Lipid 142
  • HY-W440899
    DSPE-PEG-SPDP (MW 1000)

    		Liposome Others
    DSPE-PEG-SPDP, MW 1000 is a thiol reactive PEG lipid. The polymer is amphiphilic and spontaneously forms lipid bilayer in water. It can be used to encapsulate nutrients or therapeutics for targeted drug delivery, for example mRNA or DNA vaccine, liposomal doxorubicin for anti tumor. Reagent grade, for research use only.
    DSPE-PEG-SPDP (MW 1000)
  • HY-140740
    DSPE-PEG-Maleimide, MW 5000
    1 Publications Verification

    		 Liposome Cancer
    DSPE-PEG-Maleimide, MW 5000 has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-maleimide extends blood circulation time and higher stability for encapsulated agents .
    DSPE-PEG-Maleimide, MW 5000
  • HY-W440898
    DSPE-PEG-SH (MW 5000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-SH, MW 5000 is a polyPEG attached DSPE molecule. The lipid tails allow formation of lipid bilayer in water and can be used to solubilize hydrophobic drugs while the hydrophilic core can encapsulate therapeutic agents, such as nuclein acid (mRNA/DNA), protein or peptide. Reagent grade, for research use only.
    DSPE-PEG-SH (MW 5000)
  • HY-W440690
    Cholesterol-PEG-Amine (MW 2000)

    		Liposome Cancer
    Cholesterol-PEG-Amine (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
    Cholesterol-PEG-Amine (MW 2000)
  • HY-W440896
    DSPE-PEG-SH, MW 2000

    		Liposome Others
    DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
    DSPE-PEG-SH, MW 2000
  • HY-W440902
    DSPE-PEG-IA (MW 3400)

    		Biochemical Assay Reagents Others
    DSPE-PEG-IA, MW 3400 is an iodoacetyll PEG lipid. The polymer can form lipid bilayer or micelles spontaneoulsy in water. The lipophilic tails can be used to encapsulate hydrophobic therapeutic agents while the hydrophilic head can be used to encapuslate hydrophilic drugs/nutrient, such as antibody, mRNA/DNA. The iodoacetyl group is reactive with thiol to produce a thioether linkage. Reagent grade, for research use only.
    DSPE-PEG-IA (MW 3400)
  • HY-144004A
    DSPE-PEG5000-Mal ammonium

    DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium

    		 Liposome Others
    DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
    DSPE-PEG5000-Mal ammonium
  • HY-159700
    AA3-DLin

    		Liposome Infection
    AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
    AA3-DLin
  • HY-W440891
    DSPE-PEG-OH (MW 1000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-OH, MW 1000 is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound. Reagent grade, for research use only.
    DSPE-PEG-OH (MW 1000)
  • HY-W440901
    DSPE-PEG-SPDP (MW 5000)

    		Liposome Others
    DSPE-PEG-SPDP, MW 5000 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond. Reagent grade, for research use only.
    DSPE-PEG-SPDP (MW 5000)
  • HY-W440706
    Cholesterol-PEG-alcohol (MW 2000)

    		Liposome Cancer
    Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
    Cholesterol-PEG-alcohol (MW 2000)
  • HY-W440919
    DSPE-PEG-Rhodamine, MW 2000

    		Liposome Others
    DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
    DSPE-PEG-Rhodamine, MW 2000
  • HY-W440893
    DSPE-PEG-OH (MW 5000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-OH, MW 5000 is a linear phospholipid PEG polymer. The lipid tails allow encapsulation of hdyrophobic therapeutics while the PEG chain maintains its hydrophilicity. The polymer can be used for drug nanocarrier, such as liposomal anti cancer drug or mRNA/DNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-OH (MW 5000)
  • HY-150220
    1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate

    		Liposome Others
    1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid. 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate can be used for the synthesis of phospholipid vesicle and improve the encapsulation efficiency of proteins .
    1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate
  • HY-W440694
    Cholesterol-PEG-Azide (MW 2000)

    		Liposome Cancer
    Cholesterol-PEG-Azide (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. Cholesterol-PEG-Azide (MW 2000) can be reacted with alkyne via CuAAC or SPAAC click chemistry.
    Cholesterol-PEG-Azide (MW 2000)
  • HY-W441003
    DSPE-PEG-IA (MW 2000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-IA, MW 2000 is a thiol reactive phospholipid polyPEG. The iodoacetyll group is reactive with thiol to produce a thioether linkage. The polymer can self-assemble in water to form lipid bilayer and can be used to encapsulate drugs in targeted delivery application, such as liposomal doxorubicin as an anti cancer drug or mRNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-IA (MW 2000)
  • HY-W440905
    DSPE-PEG-Vinylsulfone (MW 2000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-Vinylsulfone, MW 2000 is a phospholipid PEG which can self-assemble to form lipid bilayer in water. The polymer can be used to encapsulate therapeutics, such as nucleic acid (mRNA/DNA) or protein, in drug delivery system. The vinyl sulfone is reactive with thiol molecule via thiol-ene reaction for bioconjugation. Reagent grade, for research use only.
    DSPE-PEG-Vinylsulfone (MW 2000)
  • HY-139200
    DOTMA

    		Liposome Others
    DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
    DOTMA
  • HY-137500
    NT1-014B

    		Liposome Neurological Disease
    NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection .
    NT1-014B

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