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Results for "

methanesulfonate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Adrenergic Receptor (2) Antibiotic (2) Apoptosis (2) Autophagy (1) Bacterial (2) Biochemical Assay Reagents (4) CDK (2) Cholinesterase (ChE) (1) Complement System (1) CRFR (1) DNA/RNA Synthesis (1) Dopamine Receptor (6) ERK (1) Factor Xa (1) Fluorescent Dye (1) Glycoprotein VI (1) Histamine Receptor (2) Isotope-Labeled Compounds (5) mAChR (3) Melanocortin Receptor (1) Mitophagy (1) Monoamine Oxidase (1) P-glycoprotein (1) Parasite (1) PKC (1) PROTAC Linkers (1) Renin (1) Sodium Channel (1) Thrombin (1) TRP Channel (1) α-synuclein (1)
By Research Areas:	Cancer (14) Cardiovascular Disease (8) Endocrinology (3) Infection (5) Inflammation/Immunology (3) Metabolic Disease (11) Neurological Disease (15)

By Targets:

Acyltransferase (1)

Adrenergic Receptor (2)

Antibiotic (2)

Apoptosis (2)

Autophagy (1)

Bacterial (2)

Biochemical Assay Reagents (4)

CDK (2)

Cholinesterase (ChE) (1)

Complement System (1)

CRFR (1)

DNA/RNA Synthesis (1)

Dopamine Receptor (6)

ERK (1)

Factor Xa (1)

Fluorescent Dye (1)

Glycoprotein VI (1)

Histamine Receptor (2)

Isotope-Labeled Compounds (5)

mAChR (3)

Melanocortin Receptor (1)

Mitophagy (1)

Monoamine Oxidase (1)

P-glycoprotein (1)

Parasite (1)

PKC (1)

PROTAC Linkers (1)

Renin (1)

Sodium Channel (1)

Thrombin (1)

TRP Channel (1)

α-synuclein (1)

By Research Areas:

Cancer (14)

Cardiovascular Disease (8)

Endocrinology (3)

Infection (5)

Inflammation/Immunology (3)

Metabolic Disease (11)

Neurological Disease (15)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10550A

*Tariquidar methanesulfonate, hydrate* 45+ Cited Publications XR9576 methanesulfonate, hydrate	P-glycoprotein	Cancer
Tariquidar methanesulfonate, hydrate (XR9576 methanesulfonate, hydrate) is a potent and specific inhibitor of P-glycoprotein (P-gp) with a K_d of 5.1 nM.

HY-W015854S

*Ethyl methanesulfonate-d5*	Isotope-Labeled Compounds	Others
Ethyl methanesulfonate-d₅ is the deuterium labeled Ethyl methanesulfonate[1].

HY-16297

Abemaciclib methanesulfonate Maximum Cited Publications 81 Publications Verification LY2835219 methanesulfonate	CDK	Cancer
Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC₅₀s of 2 nM and 10 nM for CDK4 and CDK6, respectively .

HY-147301B

Resomelagon methanesulfonate AP1189 methanesulfonate	Melanocortin Receptor ERK	Inflammation/Immunology
Resomelagon methanesulfonate (AP1189 methanesulfonate) is the methanesulfonate salt form of Resomelagon (HY-147301). Resomelagon methanesulfonate is an orally active melanocortin receptor (MR) agonist. Resomelagon methanesulfonate induces ERK1/2 phosphorylation and Ca ²⁺ mobilization. Resomelagon methanesulfonate exhibits anti-inflammatory activity in mouse peritonitis and peritonitis model. Resomelagon methanesulfonate can be used for obesity and chronic inflammation research .

HY-W034344S

*Sodium methanesulfonate-d3*	Isotope-Labeled Compounds	Others
Sodium methanesulfonate-d₃ is the deuterium labeled Sodium methanesulfonate[1].

HY-B1738B

Pralidoxime methanesulfonate	Cholinesterase (ChE)	Neurological Disease
Pralidoxime methanesulfonate is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime methanesulfonate reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime methanesulfonate is an antidote for organophosphate poisoning .

HY-16297R

*Abemaciclib methanesulfonate* (Standard)**	CDK	Cancer
Abemaciclib (methanesulfonate) (Standard) is the analytical standard of Abemaciclib (methanesulfonate). This product is intended for research and analytical applications. Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC50s of 2 nM and 10 nM for CDK4 and CDK6, respectively .

HY-W004702R

*Methyl methanesulfonate* (Standard)**	Biochemical Assay Reagents	Others
Methyl methanesulfonate (Standard) is the analytical standard of Methyl methanesulfonate. This product is intended for research and analytical applications. Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W986917

Decyl methanesulfonate	Others	Metabolic Disease
Decyl methanesulfonate is an ester product.

HY-165990

Undecyl methanesulfonate	Others	Metabolic Disease
Undecyl methanesulfonate is an ester product.

HY-W011777R

*Tricaine methanesulfonate* (Standard)**	Others	Neurological Disease
Tricaine (methanesulfonate) (Standard) is the analytical standard of Tricaine (methanesulfonate). This product is intended for research and analytical applications. Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures .

HY-108464A

Phenamil methanesulfonate	Sodium Channel TRP Channel	Metabolic Disease Inflammation/Immunology
Phenamil methanesulfonate, an analog of Amiloride (HY-B0285), is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC₅₀ of 400 nM . Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca ²⁺ transport with an IC₅₀ of 140 nM in a Ca ²⁺ uptake assay . Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway . Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease .

HY-W034344

Sodium methanesulfonate	Biochemical Assay Reagents	Others
Sodium methanesulfonate is a kind of biological materials or organic compounds that are widely used in life science research .

HY-106933A

Dabelotine methanesulfonate S 12024-2	Others	Neurological Disease
Dabelotine (methanesulfonate) is a cognitive enhancer. Dabelotine (methanesulfonate) can be used for Alzheimer disease (AD) research .

HY-W004702S

*Methyl methanesulfonate-d3* METHYLMETHANE SULPHONATE-d₃	Isotope-Labeled Compounds	Others
Methyl methanesulfonate-d₃ is the deuterium labeled Methyl methanesulfonate[1].

HY-125615

DMP 728 methanesulfonate	Glycoprotein VI	Cardiovascular Disease Others
DMP 728 methanesulfonate is a platelet glycoprotein (GP) IIb/IIIa receptor antagonist. DMP 728 methanesulfonate shows dose-dependent antiplatelet and antithrombotic effects. DMP 728 methanesulfonate can be used in the study of effective antithrombotic agents in thromboembolic diseases of coronary and peripheral arteries .

HY-43948

Hexyl methanesulfonate Methanesulfonic acid hexyl ester	Others	Metabolic Disease
Hexyl methanesulfonate (Methanesulfonic acid hexyl ester) is an ester product.

HY-13735E

Quinacrine methanesulfonate Mepacrine methanesulfonate; SN-390 methanesulfonate	Parasite Apoptosis Autophagy Mitophagy	Infection Cancer
Quinacrine (Mepacrine) methanesulfonate is a potent, orally active antimalarial agent with antitumor effects in vitro and in vivo. Quinacrine dihydrochloride inhibits NF-κB and activates p53 signaling, inducing apoptosis in tumor cells .

HY-103378

NBI 35965 methanesulfonate	CRFR	Neurological Disease
NBI 35965 methanesulfonate is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K_i value of 4 nM and a pK_i value of 8.5. NBI 35965 methanesulfonate does not inhibit CRF2. NBI 35965 methanesulfonate reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC₅₀ values of 7.1 and 6.9, respectively. NBI 35965 methanesulfonate shows anxiolytic effects .

HY-W004702

Methyl methanesulfonate	Biochemical Assay Reagents	Others
Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W015854

Ethyl methanesulfonate	Biochemical Assay Reagents	Others
Ethyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-136676

Cgp 38560 methanesulfonate	Renin	Cancer
Cgp 38560 methanesulfonate is a well-tolerated renin inhibitor. Cgp 38560 methanesulfonate caused a dose-dependent decrease in angiotensin II and plasma renin activity, and a dose-dependent increase in active renin.

HY-108341A

PF-06424439 methanesulfonate 10+ Cited Publications	Acyltransferase	Metabolic Disease
PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC₅₀ of 14 nM . PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate .

HY-A0214

*Colistin methanesulfonate* sodium salt** 1 Publications Verification	Bacterial Antibiotic	Infection
Colistin methanesulfonate sodium salt exhibits MIC values ranged from 4 to 16 mg/liter against susceptible strains (P. aeruginosa) .

HY-166042

Heneicosyl methane sulfonate 1-Heneicosanol, methanesulfonate	Others	Metabolic Disease
Heneicosyl methane sulfonate (1-Heneicosanol, methanesulfonate) is an ester product.

HY-166083

Heptadecyl methane sulfonate 1-Heptadecanol, methanesulfonate	Others	Metabolic Disease
Heptadecyl methane sulfonate (1-Heptadecanol, methanesulfonate) is an ester product.

HY-W011777S

Tricaine-d5 methanesulfonate MS-222-d₅	Isotope-Labeled Compounds	Neurological Disease
Tricaine-d₅ (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used agent that can suppress or relieve pain. agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used agent that can suppress or relieve pain. in fish, has been shown to induce embryotoxic effects in zebrafish .

HY-W011777

Tricaine methanesulfonate 5 Publications Verification MS-222	Others	Neurological Disease
Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures .

HY-108166A

*Hydroxystilbamidine bis(methanesulfonate)*	Fluorescent Dye	Infection
Hydroxystilbamidine bis(methanesulfonate) is a dye that can bind to DNA and RNA; it's a fluorescent cationic dye, often used as a retrograde neuronal tracer and has also been found to be a potent inhibitor of cellular ribonucleases.

HY-W740088

Adrenochrome monoguanylhydrazone methanesulfonate S-Adchnone	Others	Cardiovascular Disease
Adrenochrome monoguanylhydrazone methanesulfonate (S-Adchnone) is an adrenochrome derivative that has a protective effect against radiation-induced damage of hematopoietic organs .

HY-165735

Octyl methane sulfonate Octyl mesylate; n-Octyl methanesulfonate; 1-Octyl mesylate	Others	Metabolic Disease
Octyl methane sulfonate (Octyl mesylate; n-Octyl methanesulfonate) is an ester product.

HY-124223

AF-DX 384 methanesulfonate	mAChR	Neurological Disease
AF-DX 384 (methanesulfonate) is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors (K_is=6.03 and 10 nM, respectively) . AF-DX 384 (methanesulfonate) reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine .

HY-120220

Piposulfan A-20968; Ancyte	Others	Cancer
Piposulfan (Ancyte) is a methanesulfonate, alkylating derivative of piperazine. Piposulfan has potential antineoplastic activity. Piposulfan can be used for the research of cancer .

HY-166217

Heptyl methane sulfonate Heptyl mesylate; n-Heptyl methanesulfonate; Heptyl triflate	Others	Metabolic Disease
Heptyl methane sulfonate (Heptyl mesylate; n-Heptyl methanesulfonate; Heptyl triflate) is an ester product.

HY-159678

4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate	PROTAC Linkers	Cancer
4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate is a PROTAC Linker. 4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate can be used in the synthesis of PROTAC SMARCA2/4-degrader-27 (HY-162834) .

HY-13720A

Pergolide mesylate 1 Publications Verification Pergolide methanesulfonate; LY127809	Dopamine Receptor	Neurological Disease
Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D₁ and D₂ receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research .

HY-B0362A

Phentolamine mesylate 3 Publications Verification Phentolamine methanesulfonate	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Phentolamine mesylate (Phentolamine methanesulfonate) is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptor that expands blood vessels to reduce peripheral vascular resistance. Phentolamine mesylate can be used for the research of pheochromocytoma-related hypertension, heart failure and erectile dysfunction .

HY-165736

10-Undecyl methane sulfonate 10-Undecen-1-ol,methanesulfonate	Others	Metabolic Disease
10-Undecyl methane sulfonate (10-Undecen-1-ol,methanesulfonate) is an ester product.

HY-50875

BCX 1470 methanesulfonate	Complement System	Inflammation/Immunology
BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC₅₀=96 nM) and C1s (IC₅₀=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.

HY-165824

11,14-Eicosadienyl methane sulfonate 11,14-Eicosadien-1-ol,methanesulfonate	Others	Metabolic Disease
11,14-Eicosadienyl methane sulfonate (11,14-Eicosadien-1-ol,methanesulfonate) is an ester product.

HY-119993

AR03 BMH-23	DNA/RNA Synthesis	Cancer
AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC₅₀ of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells .

HY-117063

LEK 8841 methanesulfonate	Others	Endocrinology
LEK 8841 methanesulfonate is a gastrointestinal calming agent with strong selective 5-HT2 receptor antagonist activity. The antipsychotic potential of LEK 8841 has made it the focus of research into alternative medicines. LEK 8841 behaves as a pure competitive antagonist in response to 5-HT and norepinephrine, with pA2 values of 7.93 and 6.45, respectively. The selectivity of LEK 8841 is better than that of the comparative drug ketanserin, making it an important reference value in corresponding receptor research. Studies related to structural modifications have shown that LEK 8841 exhibits high affinity for 5-HT2 receptors and low alpha-adrenergic receptor activity .

HY-13720AS

Pergolide-d7 mesylate Pergolide methanesulfonate-d₇; LY127809-d₇	Isotope-Labeled Compounds Dopamine Receptor	Neurological Disease
Pergolide-d₇ (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].

HY-120475A

PBT434 mesylate ATH434 mesylate	α-synuclein	Neurological Disease
PBT434 methanesulfonate is a potent, orally active and cross the blood-brain barrier α-synuclein aggregation inhibitor. PBT434 methanesulfonate can be used as a iron chelator and modulates transcellular iron trafficking. PBT434 methanesulfonate inhibits iron-mediated redox activity and iron-mediated aggregation of α-synuclein. PBT434 methanesulfonate prevents the loss of substantia nigra pars compacta neurons (SNpc). PBT434 methanesulfonate has the potential for the research of Parkinson’s disease (PD) .

HY-10281

YM-60828 methanesulfonate	Factor Xa	Cardiovascular Disease
YM-60828 is an FXa inhibitor with antithrombotic properties. In the rat arteriovenous shunt model, YM-60828 does not prolong coagulation time but reduces the levels of thrombin-antithrombin III complex (TAT) in a dose-dependent manner. YM-60828 exhibits only anti-FXa activity and does not show anti-thrombin activity, indicating that its antithrombotic effect is independent of thrombin. Therefore, the antithrombotic effect of YM-60828 can be monitored by TAT .

HY-B0520A

Benztropine mesylate 5 Publications Verification Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate	Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B0735A

Fenoldopam mesylate 4 Publications Verification Fenoldopam methanesulfonate; SKF-82526 mesylate	Dopamine Receptor Apoptosis	Cardiovascular Disease Cancer
Fenoldopam mesylate (SKF-82526) is a D₁ receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC₅₀=0.8974 μM). Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis .

HY-B0724A

Pazufloxacin mesylate T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate	Bacterial Antibiotic	Infection
Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic.

HY-10274A

Dabigatran etexilate mesylate 3 Publications Verification BIBR 1048MS; Dabigatran etexilate methanesulfonate	Thrombin	Cardiovascular Disease
Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .

HY-13866

Ro 31-8220 mesylate 10+ Cited Publications Ro 31-8220 methanesulfonate; Bisindolylmaleimide IX mesylate	PKC	Cardiovascular Disease Neurological Disease Cancer
Ro 31-8220 mesylate is a potent PKC inhibitor, with IC₅₀s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3β (IC₅₀s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7.

Cat. No.	Product Name	Type