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Results for "

palmitoyltransferase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (4) Biochemical Assay Reagents (1) COX (1) Endogenous Metabolite (5) Fungal (2) GCGR (2) GLP Receptor (2) Interleukin Related (1) MDM-2/p53 (1) Mitochondrial Metabolism (4) Neuropeptide FF Receptor (2) NO Synthase (1) Pyroptosis (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Infection (3) Inflammation/Immunology (4) Metabolic Disease (15) Neurological Disease (4)

Inhibitors & Agonists

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Products

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Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-139097

C12-Sphingosine	Others	Others
C12-Sphingosine is a short-chain Sphingosine homologue. C12-Sphingosine inhibits serine palmitoyltransferase activity in primary cultured cerebellar cells .

HY-119759A

Lipoxamycin hemisulfate	Fungal	Infection
Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

HY-50202A

Etomoxir sodium salt Maximum Cited Publications 83 Publications Verification (R)-(+)-Etomoxir sodium salt	Apoptosis	Metabolic Disease Cancer
Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig .

HY-W018026

Oxfenicine L-p-Hydroxyphenylglycine; 4-Hydroxy-L-phenylglycine; UK 25842	Others	Metabolic Disease
Oxfenicine (L-p-Hydroxyphenylglycine) is an orally active carnitine palmitoyltransferase-1 inhibitor. Oxfenicine inhibits the oxidation of fatty acid in heart. Oxfenicine protects heart from necrotic tissue damage during ischaemia .

HY-115938

BEC2	Others	Metabolic Disease
BEC2 is an ester derivative of Baicalin, with good lipid-lowering activity. BEC2 can direct activate the *carnitine palmitoyltransferase* 1A (CPT1A)** .

HY-113166

Dodecanoylcarnitine 1 Publications Verification (-)-Lauroylcarnitine	Endogenous Metabolite	Metabolic Disease
Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

HY-108433

CPT2 Carnitine palmitoyltransferase 2	Apoptosis MDM-2/p53	Metabolic Disease Cancer
CPT2 (Carnitine palmitoyltransferase 2), an enzyme that participates in fatty acid oxidation, also is a colorectal cancer (CRC) prognostic biomarker. CPT2 overexpression can activate p-p53 to increase p53 expression, thereby inhibiting tumor proliferation and promoting apoptosis. CPT2 deficiency results in the most common inherited disorder of long-chain fatty acid oxidation affecting skeletal muscle. Downregulation of CPT2 is also highly correlated with the progression of various cancers and has potential for cancer research .

HY-119759

Lipoxamycin	Fungal	Infection
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

HY-116073

L-Penicillamine	Biochemical Assay Reagents	Metabolic Disease
L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5 '-phosphate-thiazolidine adduct. L-Penicillamine is a metal chelating agent of intermediate strength .

HY-U00159

McN3716 Methyl palmoxirate; NSC359682	Mitochondrial Metabolism	Metabolic Disease
McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor.

HY-115899

Malonyl CoA Malonyl coenzyme A	Endogenous Metabolite Mitochondrial Metabolism	Metabolic Disease
Malonyl CoA is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA is also a reversible inhibitor of *mitochondrial carnitine palmitoyltransferase* (CPT) 1** .

HY-141473

Malonyl CoA tetralithium Malonyl coenzyme A tetralithium	Endogenous Metabolite Mitochondrial Metabolism	Metabolic Disease
Malonyl CoA (Malonyl coenzyme A) tetralithium is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA tetralithium is also a reversible inhibitor of *mitochondrial carnitine palmitoyltransferase* (CPT) 1** .

HY-B1334AS

Perhexiline-d11 maleate	Mitochondrial Metabolism	Cardiovascular Disease Cancer
Perhexiline-d₁₁ (maleate) is the deuterium labeled Perhexiline maleate. Perhexiline maleate is a potent carnitine palmitoyltransferase 1 (CPT 1) inhibitor with IC50s of 77 and 148 μM for rat heart and liver CPT 1, respectively.

HY-50202

Etomoxir Maximum Cited Publications 83 Publications Verification (R)-(+)-Etomoxir	Apoptosis	Metabolic Disease Cancer
Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.

HY-113166R

Dodecanoylcarnitine (Standard)	Endogenous Metabolite	Metabolic Disease
Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine. This product is intended for research and analytical applications. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

HY-W104819

4-Hydroxyphenylglyoxylate 4-Hydroxyphenylglyoxylic acid; 4-HPGA	Others	Metabolic Disease
4-Hydroxyphenylglyoxylate (4-Hydroxyphenylglyoxylic acid) is an inhibitor of *carnitine palmitoyltransferase* I (CPT I)**. 4-Hydroxyphenylglyoxylate can be used to study sensitivity changes in CPT I of liver mitochondria and fatty acid oxidation by isolated hepatocytes. 4-Hydroxyphenylglyoxylate can inhibits fatty acid oxidation .

HY-W420033

(S)-(+)-Etomoxir	Others	Others
(S)-(+)-Etomoxir is the S enantiomer of Etomoxir (HY-50202). Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig .

HY-111770

2-Bromohexadecanoic acid 2-Bromopalmitic acid; 2-Bromopalmitate	Pyroptosis	Infection Inflammation/Immunology Cancer
2-Bromohexadecanoic acid (2-Bromopalmitate; 2-BP) is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-Bromohexadecanoic acid inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis .

HY-16482

Teglicar	Endogenous Metabolite	Neurological Disease Metabolic Disease
Teglicar is a selective and reversible orally active liver isoform of *carnitine palmitoyl-transferase* 1 (L-CPT1) inhibitor with an IC₅₀ value of 0.68 μM and a K_i** value of 0.36 μM. Teglicar has a potential antihyperglycemic propert. Teglicar can be used for the research of diabetes and neurodegenerative disease including Huntington's disease (HD) .

HY-P10379

palm-PrRP31	Neuropeptide FF Receptor	Others Neurological Disease
palm-PrRP31 is a potent dual receptor agonist for both GPR10 (EC₅₀=72 pM) and NPFF-R2. palm-PrRP31 activates downstream signaling pathways through binding to its receptors, GPR10 and NPFF-R2, which results in reduced appetite and increased energy expenditure. Utilizing palm-PrRP31 facilitates the study of the mechanism of action in the nervous system, thereby elucidating the complex biological processes that regulate appetite and energy expenditure .

HY-115498

ARN14494	Apoptosis NO Synthase Interleukin Related COX	Neurological Disease Inflammation/Immunology
ARN14494 is a potent and selective *serine palmitoyltransferase* (SPT) inhibitor, with an IC₅₀ of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis**, and anti-inflammation. ARN14494 can be used for Alzheimer’s disease research .

HY-P10380

palm11-PrRP31	Neuropeptide FF Receptor	Neurological Disease
palm11-PrRP31 is a lipidized endogenous appetite inhibitory neuropeptide (PrRP) analogue. palm11-PrRP31 is GPR10 (EC₅₀=39 pM) and NPFF-R2 effective dual agonists. palm11-PrRP31 is able to mimic the natural function of PrRP by binding to these receptors to reduce food intake. palm11-PrRP31 can be used as a potential anti-obesity agent and for the study of neuropeptide-receptor interaction .

HY-P10031

SAR441255	GLP Receptor GCGR	Metabolic Disease
SAR441255 is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 displays high potency with balanced activation of all three target receptors.?SAR441255 shows positive acute glucoregulatory effectss in diabetic obese monkeys .

HY-P10031A

SAR441255 TFA	GLP Receptor GCGR	Metabolic Disease
SAR441255 TFA is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 TFA displays high potency with balanced activation of all three target receptors. SAR441255 TFA shows positive acute glucoregulatory effectss in diabetic obese monkeys .

Cat. No.	Product Name	Target	Research Area

HY-P0064

Palmitoyl Tetrapeptide-3	Peptides	Inflammation/Immunology
Palmitoyl Tetrapeptide-3 is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .

HY-P10031A

SAR441255 TFA	GLP Receptor GCGR	Metabolic Disease
SAR441255 TFA is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 TFA displays high potency with balanced activation of all three target receptors. SAR441255 TFA shows positive acute glucoregulatory effectss in diabetic obese monkeys .

HY-116073

L-Penicillamine	Biochemical Assay Reagents	Metabolic Disease
L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5 '-phosphate-thiazolidine adduct. L-Penicillamine is a metal chelating agent of intermediate strength .

HY-P10441

*S-palm* P0(180–199)**	Peptides	Inflammation/Immunology
S-palm P0(180-199) is a polypeptide that increases MHC Class II limiting reactions. S-palm P0(180-199) can be used to establish a model of chronic inflammatory demyelinating multiple radiculopathy (CIDP) .

HY-P10379

palm-PrRP31	Neuropeptide FF Receptor	Others Neurological Disease
palm-PrRP31 is a potent dual receptor agonist for both GPR10 (EC₅₀=72 pM) and NPFF-R2. palm-PrRP31 activates downstream signaling pathways through binding to its receptors, GPR10 and NPFF-R2, which results in reduced appetite and increased energy expenditure. Utilizing palm-PrRP31 facilitates the study of the mechanism of action in the nervous system, thereby elucidating the complex biological processes that regulate appetite and energy expenditure .

HY-P10380

palm11-PrRP31	Neuropeptide FF Receptor	Neurological Disease
palm11-PrRP31 is a lipidized endogenous appetite inhibitory neuropeptide (PrRP) analogue. palm11-PrRP31 is GPR10 (EC₅₀=39 pM) and NPFF-R2 effective dual agonists. palm11-PrRP31 is able to mimic the natural function of PrRP by binding to these receptors to reduce food intake. palm11-PrRP31 can be used as a potential anti-obesity agent and for the study of neuropeptide-receptor interaction .

HY-P5954

PLTX-II	Peptides	Others
PLTX-II is a calcium channel blocker. PLTX-II has a 44-residue peptide containing ten Cys residues and an O-palmitoylated threonine amide at the carboxy-terminus .

HY-P10381

palm11-TTDS-PrRP31	Peptides	Others
palm11-TTDS-PrRP31 is a strong agonist of GPR10 (EC₅₀: 84 pM). palm11-TTDS-PrRP31 has long-lasting anorexigenic effects .

HY-P10031

SAR441255	GLP Receptor GCGR	Metabolic Disease
SAR441255 is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 displays high potency with balanced activation of all three target receptors.?SAR441255 shows positive acute glucoregulatory effectss in diabetic obese monkeys .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113166

Dodecanoylcarnitine 1 Publications Verification (-)-Lauroylcarnitine	Structural Classification Immune System Disorder Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

HY-16482

Teglicar	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Teglicar is a selective and reversible orally active liver isoform of *carnitine palmitoyl-transferase* 1 (L-CPT1) inhibitor with an IC₅₀ value of 0.68 μM and a K_i** value of 0.36 μM. Teglicar has a potential antihyperglycemic propert. Teglicar can be used for the research of diabetes and neurodegenerative disease including Huntington's disease (HD) .

HY-119759

Lipoxamycin	Infection Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields Other Antibiotics	Fungal
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

HY-115899

Malonyl CoA Malonyl coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Mitochondrial Metabolism
Malonyl CoA is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA is also a reversible inhibitor of *mitochondrial carnitine palmitoyltransferase* (CPT) 1** .

HY-141473

Malonyl CoA tetralithium Malonyl coenzyme A tetralithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Mitochondrial Metabolism
Malonyl CoA (Malonyl coenzyme A) tetralithium is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA tetralithium is also a reversible inhibitor of *mitochondrial carnitine palmitoyltransferase* (CPT) 1** .

HY-113166R

Dodecanoylcarnitine (Standard)	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite	Endogenous Metabolite
Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine. This product is intended for research and analytical applications. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

Cat. No.	Compare	Product Name	Species	Source

HY-P703404

	DHHC20 Protein, Human (Sf9) palmitoyltransferase ZDHHC20; Acyltransferase ZDHHC20; 2.3.1.-; DHHC domain-containing cysteine-rich protein 20; DHHC20; Zinc finger DHHC domain-containing protein 20; ZDHHC20; Homo sapiens; Human; Acyltransferase; Transferase; 2.3.1.225	Human	Sf9 insect cells
	DHHC20 Protein, Human (Sf9) is the recombinant human-derived DHHC20, expressed by Sf9 insect cells , with tag Free labeled tag. The total length of DHHC20 Protein, Human (Sf9) is 365 a.a.,

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HY-B1334AS

Perhexiline-d11 maleate
Perhexiline-d₁₁ (maleate) is the deuterium labeled Perhexiline maleate. Perhexiline maleate is a potent carnitine palmitoyltransferase 1 (CPT 1) inhibitor with IC50s of 77 and 148 μM for rat heart and liver CPT 1, respectively.

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HY-P81167

	CPT1A Antibody CPT 1; CPT1A; CPTI-L; CPT1-L; carnitine palmitoyl transferase 1; Carnitine O-palmitoyltransferase 1, liver isoform; CPT I; Carnitine palmitoyltransferase 1A; carnitine O-palmitoyltransferase 1, liver isoform isoform 1; CPT1A_HUMAN.	WB, ELISA	Mouse
	CPT1A Antibody is an unconjugated, approximately 86 kDa, rabbit-derived, anti-CPT1A polyclonal antibody. CPT1A Antibody can be used for: WB, ELISA expriments in mouse, and predicted: human, rat background without labeling.

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palmitoyltransferase

Inhibitors & Agonists

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
Products