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Results for "

sulfone

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) ADC Linker (1) Amino Acid Derivatives (2) Antibiotic (7) Apoptosis (2) Autophagy (1) Bacterial (12) Beta-lactamase (1) Biochemical Assay Reagents (22) Cathepsin (1) Cholinesterase (ChE) (3) Cytochrome P450 (1) DNA/RNA Synthesis (3) Dopamine Receptor (1) Drug Derivative (4) Drug Intermediate (1) Drug Metabolite (21) Endogenous Metabolite (8) Fluorescent Dye (1) GABA Receptor (2) Insecticide (2) Isotope-Labeled Compounds (30) Keap1-Nrf2 (1) mTOR (2) nAChR (1) p38 MAPK (1) Parasite (20) PROTAC Linkers (15) Proton Pump (6) Pyruvate Kinase (1) Reactive Oxygen Species (ROS) (7) Reference Standards (15) SARS-CoV (1) Transglutaminase (1) VDAC (1) Virus Protease (1)
By Research Areas:	Cancer (31) Infection (30) Inflammation/Immunology (15) Metabolic Disease (13) Neurological Disease (5)
Click Chemistry:	ADC Synthesis (1) PROTAC Synthesis (9) Azide (5) Tetrazine (1) Alkynes (4)

125

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Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008614

Lansoprazole sulfone 1 Publications Verification AG-1813	Drug Metabolite Proton Pump	Metabolic Disease
Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H ⁺, K ⁺-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H ⁺, K ⁺-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease .

HY-140601

Sulfone-Bis-PEG4-acid	PROTAC Linkers	Cancer
Sulfone-Bis-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W008614R

*Lansoprazole sulfone* (Standard)** AG-1813 (Standard)	Drug Metabolite Reference Standards Proton Pump	Metabolic Disease
Lansoprazole sulfone (Standard) is the analytical standard of Lansoprazole sulfone. This product is intended for research and analytical applications. Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H+, K+-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease .

HY-137802

SAHO2 S-Adenosyl-L-homocysteine sulfone	Amino Acid Derivatives	Others
SAHO2 is the sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride (SAM) and serves as a substrate for radical SAM enzymes .

HY-Y1314S

*Dimethyl sulfone-d6*	Endogenous Metabolite	Metabolic Disease
Dimethyl sulfone-d₆ is the deuterium labeled Dimethyl sulfone. Dimethyl sulfone is an endogenous metabolite.

HY-B1787S

*Sulindac sulfone-d3*	Isotope-Labeled Compounds	Others
Sulindac sulfone-d₃ is deuterium labeled Sulindac sulfone.

HY-136451S

*Triclabendazole sulfone-d3*	Isotope-Labeled Compounds	Others
Triclabendazole sulfone-d₃ is the deuterium labeled Triclabendazole sulfone.

HY-143991S

*Modafinil acid sulfone-d5*	Isotope-Labeled Compounds	Others
Modafinil acid sulfone-d₅ is the deuterium labeled Modafinil acid sulfone .

HY-144167S

*Methiocarb sulfone-d3*	Isotope-Labeled Compounds	Others
Methiocarb sulfone-d₃ is the deuterium labeled Methiocarb sulfone .

HY-142751S

*Fenthion sulfone-d6*	Isotope-Labeled Compounds	Others
Fenthion sulfone-d₆ is the deuterium labeled Fenthion sulfone .

HY-W587559R

*Fenthion sulfone* (Standard)**	Endogenous Metabolite Reference Standards	Others
Fenthion sulfone (Standard) is the analytical standard of Fenthion sulfone. This product is intended for research and analytical applications. Fenthion sulfone is an active compound.

HY-W011239R

*Fenbendazole sulfone* (Standard)** Oxfendazole sulfone (Standard); FBZ-SO2 (Standard)	Reference Standards Parasite	Infection
Fenbendazole sulfone (Standard) is the analytical standard of Fenbendazole sulfone. This product is intended for research and analytical applications. Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent .

HY-B1787

Sulindac sulfone	mTOR Drug Metabolite	Cancer
Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research .

HY-W742805

*Sulindac Sulfone-d6*	Isotope-Labeled Compounds mTOR Drug Metabolite	Cancer
Sulindac Sulfone-d₆ is the deuterium labeled Sulindac sulfone (HY-B1787). Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research .

HY-W019773S1

*Albendazole sulfone-d3*	Isotope-Labeled Compounds Parasite Drug Metabolite	Infection
Albendazole sulfone-d₃ is the deuterium labeled Albendazole sulfone. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.

HY-113268R

*Biotin sulfone* (Standard)**	Reference Standards Endogenous Metabolite	Metabolic Disease
Biotin sulfone (Standard) is the analytical standard of Biotin sulfone. This product is intended for research and analytical applications. Biotin sulfone is first isolated as a natural metabolite of biotin.

HY-W011239

Fenbendazole sulfone Oxfendazole sulfone; FBZ-SO2	Parasite	Infection
Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent .

HY-17530R

*Aldicarb (sulfone) (Standard)*	Reference Standards Cholinesterase (ChE) Parasite Drug Metabolite	Infection
Aldicarb sulfone (Standard) is the analytical standard of Aldicarb sulfone (HY-17530). This product is intended for research and analytical applications. Aldicarb sulfone is one of the metabolites of the carbamate pesticide Aldicarb and has insecticidal activity. Aldicarb sulfone is also an inhibitor of cholinesterase.

HY-146485S

*Fulvestrant-9-sulfone-d3*	Isotope-Labeled Compounds	Others
Fulvestrant-9-sulfone-d₃ is the deuterium labeled Fulvestrant-9-sulfone .

HY-W019773S

*Albendazole sulfone-d7*	Isotope-Labeled Compounds Parasite Drug Metabolite	Infection
Albendazole sulfone-d₇ is the deuterium labeled Albendazole sulfone. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes .

HY-17530

*Aldicarb (sulfone)*	Cholinesterase (ChE) Parasite Drug Metabolite	Infection
Aldicarb sulfone is one of the metabolites of the carbamate pesticide Aldicarb and has insecticidal activity. Aldicarb sulfone is also an inhibitor of cholinesterase .

HY-W019773R

*Albendazole sulfone* (Standard)**	Reference Standards Parasite Drug Metabolite	Infection
Albendazole sulfone (Standard) is the analytical standard of Albendazole sulfone. This product is intended for research and analytical applications. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes .

HY-G0007S

*Omeprazole sulfone-d3* Omeprazole sulfone-d₃; Omeprazole sulphone-d₃	Isotope-Labeled Compounds Drug Metabolite	Infection Cancer
Omeprazole metabolite Omeprazole sulfone-d₃ is the deuterium labeled Omeprazole metabolite Omeprazole sulfone. Omeprazole sulfone is a metabolite of Omeprazole, which is a proton pump inhibitor.

HY-W709055

*Pantoprazole sulfone-d6 (major)*	Isotope-Labeled Compounds Proton Pump	Inflammation/Immunology
Pantoprazole sulfone-d₆ (major) is the deuterium labeled Pantoprazole sulfone (HY-117225). Pantoprazole sulfone is a metabolite of the gastric H+/K+ ATPase pump inhibitor Pantoprazole (HY-17507) .

HY-W587559

Fenthion sulfone	Drug Derivative	Others
Fenthion sulfone is an active compound.

HY-Y1314R

*Dimethyl sulfone* (Standard)**	Drug Metabolite Reference Standards Endogenous Metabolite	Metabolic Disease
Dimethyl sulfone (Standard) is the analytical standard of Dimethyl sulfone. This product is intended for research and analytical applications. Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-137306

Pergolide sulfone	Drug Metabolite	Others
Pergolide sulfone is a Pergolide metabolite .

HY-W800682

*Bis-sulfone-PEG4-acid*	Biochemical Assay Reagents	Others
Bis-Sulfone-PEG4-acid is a reagent with a sulfone and an acid. The sulfone group can be conjugated with thiol groups of proteins. The terminal acid reacts with primary amines with the help of activators (EDC or HATU) to from stable amide bonds.

HY-125296R

*Fipronil sulfone* (Standard)**	GABA Receptor Reference Standards	Neurological Disease
Fipronil sulfone (Standard) is the analytical standard of Fipronil sulfone. This product is intended for research and analytical applications. Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits GABA receptor with IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site).

HY-W743691

*2,4'-Dihydroxydiphenyl sulfone-d8*	Isotope-Labeled Compounds	Others
2,4'-Dihydroxydiphenyl sulfone-d₈ is deuterium-labeled 2,4'-Dihydroxydiphenyl sulfone .

HY-17008R

*Toltrazuril (sulfone) (Standard)* Ponazuril (Standard)	Reference Standards Parasite	Infection
Toltrazuril (sulfone) (Standard) is the analytical standard of Toltrazuril (sulfone). This product is intended for research and analytical applications. Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry .

HY-17008

*Toltrazuril (sulfone)* Ponazuril	Parasite	Infection
Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry .

HY-125296S

*Fipronil sulfone-13C6*	Isotope-Labeled Compounds	Others
Fipronil sulfone- ¹³C₆ is the ¹³C-labeled Fipronil sulfone .

HY-113268

Biotin sulfone	Endogenous Metabolite	Metabolic Disease
Biotin sulfone is first isolated as a natural metabolite of biotin.

HY-W097491

L-Methionine sulfone	Amino Acid Derivatives	Others
L-Methionine sulfone is a sulfonic acid derivative of L-Methionine (HY-N0326). L-Methionine in the presence of a number of oxidizing systems is readily converted to L-Methionine sulfone .

HY-G0007R

*Omeprazole sulfone* (Standard)** Omeprazole sulphone (Standard)	Reference Standards Drug Metabolite	Infection Cancer
Omeprazole sulfone (Standard) is the analytical standard of Omeprazole sulfone. This product is intended for research and analytical applications.

HY-146481S

*Lansoprazole sulfone* N-oxide-d4**	Isotope-Labeled Compounds	Others
Lansoprazole sulfone N-oxide-d₄ is the deuterium labeled Lansoprazole sulfone N-oxide .

HY-138199S1

*Omeprazole sulfone* N-oxide-d3**	Isotope-Labeled Compounds	Others
Omeprazole sulfone N-oxide-d₃ is the deuterium labeled Omeprazole sulfone N-Oxide .

HY-W008614S

*Lansoprazole sulfone-d4* AG-1813-d₄	Isotope-Labeled Compounds Proton Pump	Others
Lansoprazole sulfone-d₄ (AG-1813-d₄) is the deuterium labeled Lansoprazole sulfone. Lansoprazole sulfone-d₄ is an orally active and selective inhibitor of H ⁺, K ⁺-ATPase. Lansoprazole sulfone-d₄ can significantly stimulates gastric acid secretion by inhibiting H ⁺, K ⁺-ATPase. Lansoprazole sulfone-d₄ has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease .

HY-Z2337

Rabeprazole sulfone	Drug Intermediate	Others
Rabeprazole sulfone is a metabolite of the proton pump inhibitor Rabeprazole and is an impurity reference for Rabeprazole .

HY-17530S

*Aldicarb sulfone-13C2,d3*	Isotope-Labeled Compounds Cholinesterase (ChE) Parasite Drug Metabolite	Infection
Aldicarb sulfone- ¹³C₂,d₃ is the deuterium and ¹³C labeled Aldicarb sulfone (HY-17530). Aldicarb sulfone is one of the metabolites of the carbamate pesticide Aldicarb and has insecticidal activity. Aldicarb sulfone is also an inhibitor of cholinesterase .

HY-Y1314

Dimethyl sulfone 1 Publications Verification	Bacterial	Metabolic Disease
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-G0007

Omeprazole sulfone Omeprazole sulphone	Drug Metabolite Cytochrome P450	Others
Omeprazole sulfone is one of the major metabolites of Omeprazole (HY-B0113). Omeprazole sulfone is generated via sulfoxidation mediated by cytochrome P450 3A4 (CYP3A4) .

HY-W141863

DL-Methionine Sulfone	Drug Derivative	Others
DL-Methionine Sulfone is a Methionine (HY-13694) derivative .

HY-125296

Fipronil sulfone	GABA Receptor	Neurological Disease
Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits GABA receptor with IC₅₀ of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site).

HY-B0113S2

*Omeprazole metabolite Omeprazole sulfone* (methoxy-d3)** Omeprazole sulfone (methoxy-d₃); Omeprazole sulphone (methoxy-d₃)	Isotope-Labeled Compounds Drug Metabolite	Infection Cancer
Omeprazole metabolite Omeprazole sulfone (methoxy-d₃) is the deuterium labeled Omeprazole metabolite Omeprazole sulfone. Omeprazole sulfone is a metabolite of Omeprazole, which is a proton pump inhibitor.

HY-117225

Pantoprazole sulfone	Proton Pump	Inflammation/Immunology
Pantoprazole sulfone is a metabolite of the gastric H+/K+ ATPase pump inhibitor Pantoprazole (HY-17507) .

HY-W019773

Albendazole sulfone	Parasite Drug Metabolite	Infection
Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes .

HY-14774S1

*(Rac)-Monepantel sulfone-d5*	nAChR	Cancer
(Rac)-Monepantel sulfone-d₅ is deuterium labeled Monepantel. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.

HY-W654190

*Fipronil sulfone-13C2,15N2*	Isotope-Labeled Compounds	Others
Fipronil sulfone- ¹³C₂, ¹⁵N₂ is a deuterated labeled Fipronil sulfone .

Cat. No.	Product Name	Type

HY-W011927

4,4'-Sulfonyldiphenol Bisphenol S; Bis(4-hydroxyphenyl) sulfone	Biochemical Assay Reagents
4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W123001

Bis[2-(succinimidooxycarbonyloxy)ethyl] sulfone	Biochemical Assay Reagents
Bis[2-(succinimidooxycarbonyloxy)ethyl] sulfone is a biochemical reagent.

HY-W011927R

4,4'-Sulfonyldiphenol (Standard) Bisphenol S (Standard); Bis(4-hydroxyphenyl) sulfone (Standard)	Biochemical Assay Reagents
4,4'-Sulfonyldiphenol (Standard) is the analytical standard of 4,4'-Sulfonyldiphenol. This product is intended for research and analytical applications. 4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W440905

DSPE-PEG-Vinylsulfone (MW 2000)	Drug Delivery
DSPE-PEG-Vinylsulfone, MW 2000 is a phospholipid PEG which can self-assemble to form lipid bilayer in water. The polymer can be used to encapsulate therapeutics, such as nucleic acid (mRNA/DNA) or protein, in drug delivery system. The vinyl sulfone is reactive with thiol molecule via thiol-ene reaction for bioconjugation. Reagent grade, for research use only.

HY-W440904

DSPE-PEG-Vinylsulfone (MW 1000)	Drug Delivery
DSPE-PEG-Vinylsulfone, MW 1000 is a self-assembling PEG reagent which forms lipid bilayer. The amphiphilic polymer can be used to prepare liposome for delivering therapeutics, such as nucleic acid (mRNA/DNA) or protein. The vinyl sulfone moiety is reactive with cysteine or other thiol molecule via thiol-ene chemistry. Reagent grade, for research use only.

HY-W440907

DSPE-PEG-Vinylsulfone (MW 5000)	Drug Delivery
DSPE-PEG-Vinylsulfone, MW 5000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research use only.

HY-W1048545I

H2N-PEG-SH (MW 3400)	Drug Delivery
H2N-PEG-SH (MW 3400) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 3400) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .

HY-W1048545A

H2N-PEG-SH (MW 2000)	Drug Delivery
H2N-PEG-SH (MW 2000) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 2000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .

HY-W1048545C

H2N-PEG-SH (MW 5000)	Drug Delivery
H2N-PEG-SH (MW 5000) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 5000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .

HY-W1048545H

H2N-PEG-SH (MW 1000) Amine-PEG-Thiol (MW 1000)	Drug Delivery
H2N-PEG-SH (MW 1000) (Amine-PEG-Thiol (MW 1000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 1000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .

HY-W1048545E

H2N-PEG-SH (MW 20000) Amine-PEG-Thiol (MW 20000)	Drug Delivery
H2N-PEG-SH (MW 20000) (Amine-PEG-Thiol (MW 20000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 20000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .

HY-W1048545D

H2N-PEG-SH (MW 10000) Amine-PEG-Thiol (MW 10000)	Drug Delivery
H2N-PEG-SH (MW 10000) (Amine-PEG-Thiol (MW 10000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 10000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .

HY-W1048545J

H2N-PEG-SH (MW 40000) Amine-PEG-Thiol (MW 40000)	Drug Delivery
H2N-PEG-SH (MW 40000) (Amine-PEG-Thiol (MW 40000)) is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG-SH (MW 40000) is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113268

Biotin sulfone	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Biotin sulfone is first isolated as a natural metabolite of biotin.

HY-Y1314

Dimethyl sulfone 1 Publications Verification	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Bacterial
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-136438

Toltrazuril sulfoxide	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Parasite
Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites .

HY-113268R

*Biotin sulfone* (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Biotin sulfone (Standard) is the analytical standard of Biotin sulfone. This product is intended for research and analytical applications. Biotin sulfone is first isolated as a natural metabolite of biotin.

HY-Y1314R

*Dimethyl sulfone* (Standard)**	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Drug Metabolite Reference Standards Endogenous Metabolite
Dimethyl sulfone (Standard) is the analytical standard of Dimethyl sulfone. This product is intended for research and analytical applications. Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective .

HY-65119R

3-Chloroindole (Standard)	Structural Classification Alkaloids Microorganisms Source classification Indole Alkaloids	Endogenous Metabolite Reference Standards
Fenthion sulfone (Standard) is the analytical standard of Fenthion sulfone. This product is intended for research and analytical applications. Fenthion sulfone is an active compound.

HY-136438R

Toltrazuril sulfoxide (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Parasite
Toltrazuril sulfoxide (Standard) is the analytical standard of Toltrazuril sulfoxide. This product is intended for research and analytical applications. Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites .

Cat. No.	Product Name	Chemical Structure

HY-Y1314S

*Dimethyl sulfone-d6*
Dimethyl sulfone-d₆ is the deuterium labeled Dimethyl sulfone. Dimethyl sulfone is an endogenous metabolite.

HY-B1787S

*Sulindac sulfone-d3*
Sulindac sulfone-d₃ is deuterium labeled Sulindac sulfone.

HY-136451S

*Triclabendazole sulfone-d3*
Triclabendazole sulfone-d₃ is the deuterium labeled Triclabendazole sulfone.

HY-143991S

*Modafinil acid sulfone-d5*
Modafinil acid sulfone-d₅ is the deuterium labeled Modafinil acid sulfone .

HY-144167S

*Methiocarb sulfone-d3*
Methiocarb sulfone-d₃ is the deuterium labeled Methiocarb sulfone .

HY-142751S

*Fenthion sulfone-d6*
Fenthion sulfone-d₆ is the deuterium labeled Fenthion sulfone .

HY-W742805

*Sulindac Sulfone-d6*
Sulindac Sulfone-d₆ is the deuterium labeled Sulindac sulfone (HY-B1787). Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research .

HY-W019773S1

*Albendazole sulfone-d3*
Albendazole sulfone-d₃ is the deuterium labeled Albendazole sulfone. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.

HY-146485S

*Fulvestrant-9-sulfone-d3*
Fulvestrant-9-sulfone-d₃ is the deuterium labeled Fulvestrant-9-sulfone .

HY-W019773S

*Albendazole sulfone-d7*
Albendazole sulfone-d₇ is the deuterium labeled Albendazole sulfone. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes .

HY-G0007S

*Omeprazole sulfone-d3*
Omeprazole metabolite Omeprazole sulfone-d₃ is the deuterium labeled Omeprazole metabolite Omeprazole sulfone. Omeprazole sulfone is a metabolite of Omeprazole, which is a proton pump inhibitor.

HY-W709055

*Pantoprazole sulfone-d6 (major)*
Pantoprazole sulfone-d₆ (major) is the deuterium labeled Pantoprazole sulfone (HY-117225). Pantoprazole sulfone is a metabolite of the gastric H+/K+ ATPase pump inhibitor Pantoprazole (HY-17507) .

HY-W743691

*2,4'-Dihydroxydiphenyl sulfone-d8*
2,4'-Dihydroxydiphenyl sulfone-d₈ is deuterium-labeled 2,4'-Dihydroxydiphenyl sulfone .

HY-125296S

*Fipronil sulfone-13C6*
Fipronil sulfone- ¹³C₆ is the ¹³C-labeled Fipronil sulfone .

HY-146481S

*Lansoprazole sulfone* N-oxide-d4**
Lansoprazole sulfone N-oxide-d₄ is the deuterium labeled Lansoprazole sulfone N-oxide .

HY-138199S1

*Omeprazole sulfone* N-oxide-d3**
Omeprazole sulfone N-oxide-d₃ is the deuterium labeled Omeprazole sulfone N-Oxide .

HY-W008614S

Lansoprazole sulfone-d4

Lansoprazole sulfone-d₄ (AG-1813-d₄) is the deuterium labeled Lansoprazole sulfone. Lansoprazole sulfone-d₄ is an orally active and selective inhibitor of H ⁺, K ⁺-ATPase. Lansoprazole sulfone-d₄ can significantly stimulates gastric acid secretion by inhibiting H ⁺, K ⁺-ATPase. Lansoprazole sulfone-d₄ has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease .

HY-17530S

*Aldicarb sulfone-13C2,d3*
Aldicarb sulfone- ¹³C₂,d₃ is the deuterium and ¹³C labeled Aldicarb sulfone (HY-17530). Aldicarb sulfone is one of the metabolites of the carbamate pesticide Aldicarb and has insecticidal activity. Aldicarb sulfone is also an inhibitor of cholinesterase .

HY-B0113S2

*Omeprazole metabolite Omeprazole sulfone* (methoxy-d3)**
Omeprazole metabolite Omeprazole sulfone (methoxy-d₃) is the deuterium labeled Omeprazole metabolite Omeprazole sulfone. Omeprazole sulfone is a metabolite of Omeprazole, which is a proton pump inhibitor.

HY-14774S1

*(Rac)-Monepantel sulfone-d5*
(Rac)-Monepantel sulfone-d₅ is deuterium labeled Monepantel. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.

HY-W654190

*Fipronil sulfone-13C2,15N2*
Fipronil sulfone- ¹³C₂, ¹⁵N₂ is a deuterated labeled Fipronil sulfone .

HY-138199S

*Omeprazole sulfone* N-oxide-13C,d3**
Omeprazole sulfone N-oxide- ¹³C,d₃ is the deuterium and ¹³C labeled Omeprazole sulfone N-Oxide .

HY-G0007S1

*Omeprazole sulfone-13C,d3*
Omeprazole metabolite Omeprazole sulfone- ¹³C,d₃ is the deuterium and ¹³C labeled Omeprazole metabolite Omeprazole sulfone .

HY-W008614S1

Lansoprazole sulfone-13C6

Lansoprazole sulfone- ¹³C₆ (AG-1813- ¹³C₆) is ¹³C labeled Lansoprazole sulfone. Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H ⁺, K ⁺-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H ⁺, K ⁺-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease .

HY-B0965S

Thioridazine-d3 2-Sulfone

Thioridazine-d₃ 2-Sulfone is the deuterium labeled Thioridazine hydrochloride. Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs) .

HY-W747290

*Bis(methylsulfinylethyl)sulfone-13C4*
Bis(methylsulfinylethyl)sulfone- ¹³C₄ is the ¹³C-labeled 1-(Methylsulfinyl)-2-((2-(methylsulfinyl)ethyl)sulfonyl)ethane (HY-W713530).

HY-B0688S3

Dapsone-15N2

Dapsone- ¹⁵N₂ (4,4′-Diaminodiphenyl sulfone- ¹⁵N₂) is ¹⁵N labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0688S1

Dapsone-d4

Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-W653930

4,4'-Sulfonyldiphenol-13C12
4,4'-Sulfonyldiphenol- ¹³C₁₂ (Bisphenol S- ¹³C₁₂) is ¹³C labeled 4,4'-Sulfonyldiphenol. 4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-B0688S2

Dapsone-13C12

Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-W654084

24 Bisphenol S-13C12
24 Bisphenol S- ¹³C₁2 is the ¹³C-labeled 2,4'-Dihydroxydiphenyl sulfone (HY-W128222). 2,4'-Dihydroxydiphenyl sulfone is an active small molecule and can be used as fire-resistant polyester compositions .

HY-34444S

1,1-Dioxothiolan-d8
1,1-Dioxothiolan-d₈ is the deuterium labeled 1,1-Dioxothiolan .

HY-B0688S

Dapsone-d8
Dapsone-d₈ is a deuterium labeled Dapsone. Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with antibacterial, antigenic and anti-inflammatory activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone can be used as an anticonvulsant and also in the research of skin and glioblastoma diseases .

Cat. No.	Product Name		Classification

HY-138745

*Bis-sulfone-PEG3-Azide*		ADC Synthesis Azide
Bis-sulfone-PEG3-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bis-sulfone-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-138747

*Bis-sulfone-PEG4-Tetrazine*		PROTAC Synthesis Tetrazine
Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-sulfone-PEG4-Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-140610

*Propargyl-PEG4-Sulfone-PEG4-acid*		Alkynes PROTAC Synthesis
Propargyl-PEG4-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Sulfone-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140611

*Propargyl-peg3-sulfone-peg3-propargyl*		Alkynes PROTAC Synthesis
Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-peg3-sulfone-peg3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140612

*Propargyl-PEG4-Sulfone-PEG4-Boc*		Alkynes PROTAC Synthesis
Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG4-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140608

*m-PEG3-Sulfone-PEG4-propargyl*		Alkynes PROTAC Synthesis
m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG3-Sulfone-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140602

*Azido-PEG3-Sulfone-PEG4-acid*		PROTAC Synthesis Azide
Azido-PEG3-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Sulfone-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140604

*Azido-PEG3-Sulfone-PEG4-Boc*		PROTAC Synthesis Azide
Azido-PEG3-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Sulfone-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140603

*Azide-PEG3-Sulfone-PEG3-azide*		PROTAC Synthesis Azide
Azide-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG3-Sulfone-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140606

*m-PEG3-Sulfone-PEG3-azide*		PROTAC Synthesis Azide
m-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG3-Sulfone-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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