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thymine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Angiotensin-converting Enzyme (ACE) (2) Bacterial (1) DNA/RNA Synthesis (5) Endogenous Metabolite (18) Fluorescent Dye (2) Influenza Virus (1) Isotope-Labeled Compounds (3) Nucleoside Antimetabolite/Analog (11) Parasite (2) PPAR (1) Thymidylate Synthase (1)
By Research Areas:	Cancer (15) Cardiovascular Disease (4) Infection (4) Inflammation/Immunology (2) Metabolic Disease (10) Neurological Disease (1)
Oligonucleotides:	Nucleosides and their Analogs (6) Nucleoside Phosphoramidites (2)

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Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010450

*Thymine*	Endogenous Metabolite	Metabolic Disease Cancer
Thymine, one of the four bases of DNA, is a substrate for rat liver dihydropyrimidine dehydrogenase (DPD), with a K_m value of 2.2 μM, K_i of 24 μM (using 5-FU as the DPD substrate), and a specific activity of 0.68 nmol/min/mg .

HY-W010450S4

Thymine-d4-1	Endogenous Metabolite	Cancer
Thymine-d₄-1 is the deuterium labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].

HY-W010450R

Thymine (Standard)	Endogenous Metabolite	Metabolic Disease Cancer
Thymine (Standard) is the analytical standard of Thymine. This product is intended for research and analytical applications. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

HY-W010450S

Thymine-d4	Endogenous Metabolite	Metabolic Disease Cancer
Thymine-d₄ is the deuterium labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

HY-W010450S3

Thymine-13C	Endogenous Metabolite DNA/RNA Synthesis	Cancer
Thymine- ¹³C is the ¹³C labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].

HY-W010450S2

Thymine-15N2	Endogenous Metabolite	Cancer
Thymine- ¹⁵N₂ is the ¹⁵N labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].

HY-W747214

Thymine-15N2,13C	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Thymine- ¹⁵N₂, ¹³C is the ¹³C and ¹⁵N labeled Thymine (HY-W010450). Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluorouracil (HY-90006) in cancer treatment, with a K_m of 2.3 μM .

HY-137848

Thymine 1-β-D-arabinofuranoside	Nucleoside Antimetabolite/Analog	Others
Thymine 1-β-D-arabinofuranoside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-150857S

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4	Isotope-Labeled Compounds	Others
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-W010450S5

Thymine-13C5,15N2 5-Methyluacil-¹³C₅,¹⁵N,¹⁵N₂	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease Cancer
Thymine- ¹³C₅, ¹⁵N₂ (5-Methyluacil- ¹³C₅, ¹⁵N₂) is ¹³C and ¹⁵N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a K_m of 2.3 μM .

HY-W550365

1-(alpha-L-Threofuranosyl)thymine	Nucleoside Antimetabolite/Analog	Cancer
1-(alpha-L-Threofuranosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-129594

DANP	Fluorescent Dye	Others
DANP is a bulge base recognition probe that strongly and specifically binds to the single cytosine and thymine bulges. DANP could stabilize not only a single cytosine but also the thymine bulge in duplex DNA .

HY-129594A

DANP dihydrochloride	Fluorescent Dye	Others
DANP dihydrochloride is a bulge base recognition probe that strongly and specifically binds to the single cytosine and thymine bulges. DANP dihydrochloride could stabilize not only a single cytosine but also the thymine bulge in duplex DNA .

HY-111638

1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Infection
1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine is a bicyclic nucleoside.

HY-154524

1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine	Nucleoside Antimetabolite/Analog	Others
1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152973

7'-O-DMT-morpholino thymine	Nucleoside Antimetabolite/Analog	Others
7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-154319

1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine	Nucleoside Antimetabolite/Analog	Cancer
1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-136559

6-Azathymine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Bacterial Influenza Virus	Infection
6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities .

HY-W559353

1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine	Nucleoside Antimetabolite/Analog	Cancer
1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154604

*1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine* 3'-CE phosphoramidite**	Nucleoside Antimetabolite/Analog	Cancer
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-154686

1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine	Nucleoside Antimetabolite/Analog	Cancer
1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-135218

AV-153	DNA/RNA Synthesis	Cancer
AV-153, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 has anti-cancer activity .

HY-135218A

AV-153 free base 1 Publications Verification	DNA/RNA Synthesis	Cancer
AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity .

HY-113380

(S)-b-aminoisobutyric acid 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
(S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine.

HY-113126A

3-Hydroxyisobutyric acid sodium	Endogenous Metabolite	Others
3-Hydroxyisobutyric acid sodium is an important interorgan metabolite, an intermediate in the pathways of l-valine and thymine and a good gluconeogenic substrate.

HY-113126

3-Hydroxyisobutyric acid	Endogenous Metabolite	Others
3-Hydroxyisobutyric acid is an important interorgan metabolite, an intermediate in the pathways of l-valine and thymine and a good gluconeogenic substrate.

HY-112669

5-Chloro-2'-deoxyuridine 2 Publications Verification 5-Chlorodeoxyuridine; CldU	Nucleoside Antimetabolite/Analog	Neurological Disease
5-Chloro-2'-deoxyuridine, a thymine analog, is to study the potential of hypochlorous acid damage to DNA and DNA precursors.

HY-77537

7-Deazaxanthine 7DX	Thymidylate Synthase	Cardiovascular Disease
7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase). 7-Deazaxanthine inhibits TPase reaction in a concentration-dependent manner with an IC₅₀ value of 40 μM. 7-Deazaxanthine also has a significant angiogenesis inhibitory effect .

HY-N6787

5,6-Dihydro-5-methyluracil 2 Publications Verification Dihydrothymine	Endogenous Metabolite	Metabolic Disease
5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels .

HY-12404

Diminazene aceturate 5 Publications Verification Diminazene diaceturate	Parasite Angiotensin-converting Enzyme (ACE)	Infection Inflammation/Immunology
Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties .

HY-N6787S

5,6-Dihydro-5-methyluracil-d6 Dihydrothymine-d₆	Endogenous Metabolite	Metabolic Disease
5,6-Dihydro-5-methyluracil-d₆ is the deuterium labeled 5,6-Dihydro-5-methyluracil. 5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels[1].

HY-126181

5-Formylcytosine	Endogenous Metabolite	Others
5-Formylcytosine is a modified base, which is oxidized from 5-methylcytosine. 5-Formylcytosine is a intermediate of in the active DNA demethylation .

HY-165098

3-Aminoisobutyric acid sodium salt β-Aminoisobutyric acid sodium salt; BAIBA sodium salt	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
3-Aminoisobutyric acid (β-Aminoisobutyric acid) sodium salt has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid sodium salt increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid sodium salt attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid sodium salt is a catabolic metabolite of thymine and valine in skeletal muscle .

HY-W012974

3-Aminoisobutyric acid β-Aminoisobutyric acid; BAIBA	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
3-Aminoisobutyric acid (β-Aminoisobutyric acid) has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid is a catabolic metabolite of thymine and valine in skeletal muscle .

HY-12404R

Diminazene (aceturate) (Standard)	Parasite Angiotensin-converting Enzyme (ACE)	Infection Inflammation/Immunology
Diminazene (aceturate) (Standard) is the analytical standard of Diminazene (aceturate). This product is intended for research and analytical applications. Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties .

HY-W341499

5-Formyl-2'-deoxyuridine	Endogenous Metabolite	Others
5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein .

HY-W012974R

3-Aminoisobutyric acid (Standard) β-Aminoisobutyric acid (Standard); BAIBA (Standard)	Endogenous Metabolite AMPK PPAR	Cardiovascular Disease Metabolic Disease
3-Aminoisobutyric acid (Standard) is the analytical standard of 3-Aminoisobutyric acid. This product is used for research and analytical applications. 3-Aminoisobutyric acid (β-Aminoisobutyric acid) exhibits anti-inflammatory and antioxidant effects. It increases the expression of brown fat cell-specific genes in white adipose tissue and enhances fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid alleviates insulin resistance and inflammation induced by palmitic acid or a high-fat diet in mice via the AMPK–PPARδ-dependent pathway. 3-Aminoisobutyric acid is a catabolite of thymine and valine in skeletal muscle .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010450

*Thymine*	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymine, one of the four bases of DNA, is a substrate for rat liver dihydropyrimidine dehydrogenase (DPD), with a K_m value of 2.2 μM, K_i of 24 μM (using 5-FU as the DPD substrate), and a specific activity of 0.68 nmol/min/mg .

HY-W010450R

Thymine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Thymine (Standard) is the analytical standard of Thymine. This product is intended for research and analytical applications. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

HY-113380

(S)-b-aminoisobutyric acid 1 Publications Verification	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine.

HY-113126

3-Hydroxyisobutyric acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Hydroxyisobutyric acid is an important interorgan metabolite, an intermediate in the pathways of l-valine and thymine and a good gluconeogenic substrate.

HY-N6787

5,6-Dihydro-5-methyluracil 2 Publications Verification Dihydrothymine	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels .

HY-W012974

3-Aminoisobutyric acid β-Aminoisobutyric acid; BAIBA	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Aminoisobutyric acid (β-Aminoisobutyric acid) has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid is a catabolic metabolite of thymine and valine in skeletal muscle .

Cat. No.	Compare	Product Name	Species	Source

HY-P702783

	TDG Protein, Human (His) G/T mismatch-specific thymine DNA glycosylase; thymine-DNA glycosylase; EC:3.2.2.29	Human	E. coli
	TDG Protein, Human (His) is the recombinant human-derived TDG, expressed by E. coli , with N-10*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W010450S4

Thymine-d4-1
Thymine-d₄-1 is the deuterium labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].

HY-W010450S

Thymine-d4
Thymine-d₄ is the deuterium labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

HY-W010450S3

Thymine-13C
Thymine- ¹³C is the ¹³C labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].

HY-W010450S2

Thymine-15N2
Thymine- ¹⁵N₂ is the ¹⁵N labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].

HY-W747214

Thymine-15N2,13C
Thymine- ¹⁵N₂, ¹³C is the ¹³C and ¹⁵N labeled Thymine (HY-W010450). Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluorouracil (HY-90006) in cancer treatment, with a K_m of 2.3 μM .

HY-150857S

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-W010450S5

Thymine-13C5,15N2
Thymine- ¹³C₅, ¹⁵N₂ (5-Methyluacil- ¹³C₅, ¹⁵N₂) is ¹³C and ¹⁵N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a K_m of 2.3 μM .

HY-N6787S

5,6-Dihydro-5-methyluracil-d6
5,6-Dihydro-5-methyluracil-d₆ is the deuterium labeled 5,6-Dihydro-5-methyluracil. 5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels[1].

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thymine

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Recombinant Proteins

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