Search Result
Results for "
vehicle
" in MedChemExpress (MCE) Product Catalog:
30
Biochemical Assay Reagents
9
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-125853
-
|
Soybean phosphatidylcholine
|
Liposome
|
Neurological Disease
Endocrinology
|
|
Phosphatidylcholines,soya is a phosphatidylcholine from soybean used in the preparation of liposomes. Phosphatidylcholines,soya can be used as a vehicle in animal agent administration .
|
-
-
- HY-157049
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Caprylocaproyl Macrogolglycerides is a lipoidic excipient/vehicle in an oral capsule formulation. Caprylocaproyl Macrogolglycerides can enhance the absorption of small molecule compounds .
|
-
-
- HY-139413
-
|
|
Toll-like Receptor (TLR)
|
Cancer
|
|
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .
|
-
-
- HY-151509
-
|
|
Liposome
|
Cancer
|
|
A2-Iso5-2DC18 is a dihydroimidazole-linked lipid, served as potent mRNA delivery vehicle. A2-Iso5-2DC18 can be used for antitumor research, including B16F10 melanoma. .
|
-
-
- HY-145782
-
-
-
- HY-142987
-
-
-
- HY-P4117
-
-
-
- HY-W1123940C
-
-
-
- HY-W1123940
-
-
-
- HY-W1123940D
-
-
-
- HY-W1123940B
-
-
-
- HY-W1123940A
-
-
-
- HY-142977
-
|
|
Liposome
Drug Intermediate
|
Others
|
|
6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate in the synthesis of ALC-0315. ALC-0315 is an ionizable amino lipid. ALC-0315 is a key component of LNP delivery vehicles. 6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an effective delivery vehicle of mRNA .
|
-
-
- HY-112251
-
D-Lin-MC3-DMA
Maximum Cited Publications
84 Publications Verification
|
Liposome
|
Cancer
|
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
-
- HY-101103
-
|
(2-Hydroxypropyl)-β-cyclodextrin
|
Biochemical Assay Reagents
|
Cancer
|
|
HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability.
|
-
-
- HY-P4250A
-
-
-
- HY-P990724
-
|
DNL-310
|
Steroid Sulfatase
|
Metabolic Disease
|
|
Tividenofusp alfa (DNL-310) is a fusion protein composed of IDS fused to Denali's proprietary Enzyme Transport Vehicle (ETV) .
|
-
-
- HY-151511
-
|
|
Liposome
|
Cancer
|
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
-
- HY-156829A
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA)：glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
|
-
-
- HY-156829
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) is a matrix materia, with lactic acid (LA)：glycolic acid (GA) = 1:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
|
-
-
- HY-W090151
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Silyl-ether based ROMP monomer iPrSi is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .
|
-
-
- HY-Y0683A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Petrolatum (white) is an ointment vehicle for many agents, due to its low skin irritation. Petrolatum (white) is a safe, effective wound care ointment for ambulatory surgery .
|
-
-
- HY-160473A
-
|
|
Microtubule/Tubulin
|
Cancer
|
|
TAM557 TFA is a cytotoxic tubulysin compounds, which is modified to be used for conjugation to transport vehicles that are targeting molecules, such as proteins, peptides, small molecules or polymeric carriers which can carry a targeting principle .
|
-
-
- HY-W440727
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Vinylsulfone (MW 2000) is a thiol reactive polyPEG via thiol-ene reaction to form a thioether bond. It can self-assemble in water and is used to prepare liposome as drug vehicle for targeted delivery into tissues.
|
-
-
- HY-143210
-
|
|
Liposome
|
Metabolic Disease
|
|
Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .
|
-
-
- HY-142985
-
|
|
Liposome
|
Metabolic Disease
|
|
Oleyl Mesylate is a derivative of Oleyl Alcohol. Oleyl Alcohol has been incorporated into various formulations for drug delivery .
|
-
-
- HY-143692
-
-
-
- HY-109506S6
-
|
129Y83-d66
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DPPC-d66 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
|
-
-
- HY-109506S8
-
|
129Y83-d75
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DPPC-d75 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
|
-
-
- HY-109506S7
-
|
129Y83-d71
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DPPC-d71 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
|
-
-
- HY-109506S5
-
|
129Y83-d13
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DPPC-d13 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
|
-
-
- HY-109506S4
-
|
129Y83-d4
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DPPC-d4 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in m
|
-
-
- HY-109506S1
-
|
129Y83-d9
|
Endogenous Metabolite
|
Others
|
|
DPPC-d9 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .
|
-
-
- HY-109506S
-
|
129Y83-d62
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DPPC-d62 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .
|
-
-
- HY-109506S3
-
|
129Y83-d9-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DPPC-d9-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .
|
-
-
- HY-W145518
-
|
|
Endogenous Metabolite
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. Pectin involves in the formation of nanoparticles as a delivery vehicle of agents. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa .
|
-
-
- HY-112251S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle .
|
-
-
- HY-112251GL
-
|
|
Liposome
|
Cancer
|
|
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
-
- HY-163977
-
|
2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene
|
Biochemical Assay Reagents
|
Others
|
|
Silyl-ether based ROMP Monomer (2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene) is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .
|
-
-
- HY-160581
-
|
|
Liposome
|
Others
|
|
OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect .
|
-
-
- HY-P10514
-
|
|
Small Interfering RNA (siRNA)
|
Others
|
|
Transportan 10 is a derivative of Transportan (HY-P1732) and is an amphiphilic cell penetrating peptide (CPP). Transportan 10 helps molecules penetrate cell membrane barriers by directly interacting with the lipid bilayer. Transportan 10 can be used in gene therapy or siRNA delivery vector research .
|
-
-
- HY-138170
-
|
|
Liposome
SARS-CoV
|
Infection
|
|
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
|
-
-
- HY-155918
-
|
mPEG-Aldehyde (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 1000) participates in the formation of a three-dimensional porous scaffold that carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
-
- HY-155920
-
|
mPEG-Aldehyde (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 3400) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
-
- HY-155917
-
|
mPEG-Aldehyde (MW 750)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 750) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
-
- HY-155922
-
|
mPEG-Aldehyde (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 10000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
-
- HY-W440883
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
-
- HY-155916
-
|
mPEG-Aldehyde (MW 550)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 550) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
-
- HY-B2247A
-
|
poly(lactic-co-glycolic acid) (75:25)
|
Biochemical Assay Reagents
|
Others
|
|
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
|
-
-
- HY-155923
-
|
mPEG-Aldehyde (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 20000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155919
-
|
mPEG-Aldehyde (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 2000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155915
-
|
mPEG-Aldehyde (MW 350)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 350) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155921
-
|
mPEG-Aldehyde (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CHO (MW 5000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-154644
-
|
|
Biochemical Assay Reagents
Dopamine Receptor
|
Cancer
|
|
Soya Lecithin is a phospholipid mixture that can be used as a drug delivery vehicle and is a pharmaceutical excipient. Soya Lecithin can form a lipid bilayer structure through self-assembly, and its binding properties are amphiphilic (hydrophilic head and hydrophobic tail), encapsulating hydrophobic drugs. Soya Lecithin forms stable nanoliposomes or microemulsions, improves the solubility and cellular uptake efficiency of poorly soluble drugs (such as Curcumin (HY-N0005)), and exerts activities such as enhancing drug delivery and regulating cell proliferation .
|
-
- HY-D1005A6
-
|
PEG-PPG-PEG, 2200 (Average)
|
Biochemical Assay Reagents
|
Others
|
|
Poloxamer 124 L44 is a block polymer of polyoxyethylene and polyoxypropylene and a hydrophobic surfactant. Poloxamer 124 L44 causes eye irritation and exhibits oral toxicity in albino rats with an LD50 of 5 g/kg. Poloxamer 124 L44 has reversible adverse effects on triglyceride and cholesterol transport in the lymphatic system of rats. Poloxamer 124 L44 can form thermoreversible hydrogels and is used as a food additive and as a drug delivery vehicle in cosmetics, pharmaceuticals, and tissue engineering[1][2][3].
|
-
- HY-138170A
-
|
|
Liposome
SARS-CoV
|
Infection
|
|
ALC-0315 (Excipient, GMP Like) is the GMP Like class ALC-0315 (HY-138170), and can be used as pharmaceutical excipients. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 (Excipient, GMP Like) can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
|
-
- HY-106031
-
|
|
Topoisomerase
|
Cancer
|
|
F-14512 is a targeted cytotoxic compound that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 combines an epipodophyllotoxin core that targets topoisomerase II with a spermine group that acts as a cell delivery vehicle, with improved selectivity for tumor cells. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and demonstrates high potency in multiple human cell lines (median IC50=0.18 μM). In the MX1 breast tumor xenograft model, F-14512 exhibits potent antitumor activity .
|
-
- HY-16387
-
|
|
VEGFR
|
Others
|
|
PF-00337210 is a potent and selective inhibitor of VEGFRs, designed for treating age-related macular degeneration via intravitreal injection. The formulation strategy focused on developing an ophthalmic solution that would precipitate upon injection into the vitreous, ensuring sustained drug delivery. Challenges included maintaining low dosing volumes, selecting safe excipients for intravitreal use, and addressing the drug's unique physicochemical properties. The final formulation, an isotonic solution in a citrate-buffered vehicle with NaCl, demonstrated stability, potency, and recovery through intravitreal dosing syringes. It formed a depot upon injection into vitreous humor, representing a novel nonpolymeric in situ-forming depot formulation for intravitreal drug delivery .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-112251GL
-
|
|
Fluorescent Dye
|
|
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
| Cat. No. |
Product Name |
Type |
-
- HY-125853
-
|
Soybean phosphatidylcholine
|
Drug Delivery
|
|
Phosphatidylcholines,soya is a phosphatidylcholine from soybean used in the preparation of liposomes. Phosphatidylcholines,soya can be used as a vehicle in animal agent administration .
|
-
- HY-139413
-
|
|
Carbohydrates
|
|
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .
|
-
- HY-142977
-
|
|
Drug Delivery
|
|
6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate in the synthesis of ALC-0315. ALC-0315 is an ionizable amino lipid. ALC-0315 is a key component of LNP delivery vehicles. 6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an effective delivery vehicle of mRNA .
|
-
- HY-145782
-
|
|
Drug Delivery
|
|
Witepsol is a selective lipid-based vehicle for use in drug delivery systems .
|
-
- HY-142987
-
|
|
Drug Delivery
|
|
Linoleyl methane sulfonate is a selective lipid-based vehicle for use in drug delivery systems .
|
-
- HY-W1123940C
-
|
|
Drug Delivery
|
|
DMG-PEG-OH (MW 5000) is a PEG derivative that can be used to construct drug delivery vehicles.
|
-
- HY-W1123940
-
|
|
Drug Delivery
|
|
DMG-PEG-OH (MW 1000) is a PEG derivative that can be used to construct drug delivery vehicles.
|
-
- HY-W1123940D
-
|
|
Drug Delivery
|
|
DMG-PEG-OH (MW 10000) is a PEG derivative that can be used to construct drug delivery vehicles.
|
-
- HY-W1123940B
-
|
|
Drug Delivery
|
|
DMG-PEG-OH (MW 3400) is a PEG derivative that can be used to construct drug delivery vehicles.
|
-
- HY-W1123940A
-
|
|
Drug Delivery
|
|
DMG-PEG-OH (MW 2000) is a PEG derivative that can be used to construct drug delivery vehicles.
|
-
- HY-112251
-
D-Lin-MC3-DMA
Maximum Cited Publications
84 Publications Verification
|
Drug Delivery
|
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
- HY-101103
-
|
(2-Hydroxypropyl)-β-cyclodextrin
|
Drug Delivery
|
|
HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability.
|
-
- HY-151511
-
|
|
Drug Delivery
|
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
- HY-W090151
-
|
|
Biochemical Assay Reagents
|
|
Silyl-ether based ROMP monomer iPrSi is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .
|
-
- HY-143210
-
|
|
Drug Delivery
|
|
Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .
|
-
- HY-142985
-
|
|
Drug Delivery
|
|
Oleyl Mesylate is a derivative of Oleyl Alcohol. Oleyl Alcohol has been incorporated into various formulations for drug delivery .
|
-
- HY-143692
-
|
|
Drug Delivery
|
|
SQDG inhibits topoisomerase I and P-selectin receptor, exhibits anti-inflammatory, antiviral and antitumor activities. SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations .
|
-
- HY-112251GL
-
|
|
Biochemical Assay Reagents
|
|
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
- HY-163977
-
|
2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene
|
Biochemical Assay Reagents
|
|
Silyl-ether based ROMP Monomer (2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene) is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .
|
-
- HY-138170
-
|
|
Drug Delivery
|
|
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
|
-
- HY-155918
-
|
mPEG-Aldehyde (MW 1000)
|
Drug Delivery
|
|
mPEG-CHO (MW 1000) participates in the formation of a three-dimensional porous scaffold that carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155920
-
|
mPEG-Aldehyde (MW 3400)
|
Drug Delivery
|
|
mPEG-CHO (MW 3400) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155917
-
|
mPEG-Aldehyde (MW 750)
|
Drug Delivery
|
|
mPEG-CHO (MW 750) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155922
-
|
mPEG-Aldehyde (MW 10000)
|
Drug Delivery
|
|
mPEG-CHO (MW 10000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155916
-
|
mPEG-Aldehyde (MW 550)
|
Drug Delivery
|
|
mPEG-CHO (MW 550) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155923
-
|
mPEG-Aldehyde (MW 20000)
|
Drug Delivery
|
|
mPEG-CHO (MW 20000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155919
-
|
mPEG-Aldehyde (MW 2000)
|
Drug Delivery
|
|
mPEG-CHO (MW 2000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155915
-
|
mPEG-Aldehyde (MW 350)
|
Drug Delivery
|
|
mPEG-CHO (MW 350) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155921
-
|
mPEG-Aldehyde (MW 5000)
|
Drug Delivery
|
|
mPEG-CHO (MW 5000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-D1005A6
-
|
PEG-PPG-PEG, 2200 (Average)
|
Co-solvents
|
|
Poloxamer 124 L44 is a block polymer of polyoxyethylene and polyoxypropylene and a hydrophobic surfactant. Poloxamer 124 L44 causes eye irritation and exhibits oral toxicity in albino rats with an LD50 of 5 g/kg. Poloxamer 124 L44 has reversible adverse effects on triglyceride and cholesterol transport in the lymphatic system of rats. Poloxamer 124 L44 can form thermoreversible hydrogels and is used as a food additive and as a drug delivery vehicle in cosmetics, pharmaceuticals, and tissue engineering[1][2][3].
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4117
-
-
- HY-P4250
-
|
|
Peptides
|
Others
|
|
Tetraarginine (RRRR), consisting of four arginines, is used in cell-penetrating peptide-based gene delivery vehicles .
|
-
- HY-P4250A
-
-
- HY-P10514
-
|
|
Small Interfering RNA (siRNA)
|
Others
|
|
Transportan 10 is a derivative of Transportan (HY-P1732) and is an amphiphilic cell penetrating peptide (CPP). Transportan 10 helps molecules penetrate cell membrane barriers by directly interacting with the lipid bilayer. Transportan 10 can be used in gene therapy or siRNA delivery vector research .
|
-
- HY-P10794
-
|
|
Peptides
|
Cancer
|
|
LH2 peptide is a pH-responsive cell-penetrating peptide dimer with the amino acid sequence LHHLCHLLHHLCHLAG. It can increase its uptake in tumor cells under weakly acidic conditions (such as the tumor microenvironment) through the protonation of histidine residues (pKa approximately 6). When conjugated with the anticancer drug Paclitaxel (HY-B0015), the PTX-LH2 conjugate showed superior tumor suppression effects compared to paclitaxel alone in a subcutaneous breast tumor model. The LH2 peptide holds potential as a drug delivery vehicle in cancer research .
|
| Cat. No. |
Product Name |
Target |
Research Area |
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-109506S1
-
|
|
|
DPPC-d9 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .
|
-
-
- HY-109506S
-
|
|
|
DPPC-d62 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .
|
-
-
- HY-109506S6
-
|
|
|
DPPC-d66 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
|
-
-
- HY-109506S8
-
|
|
|
DPPC-d75 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
|
-
-
- HY-109506S7
-
|
|
|
DPPC-d71 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
|
-
-
- HY-109506S5
-
|
|
|
DPPC-d13 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
|
-
-
- HY-109506S4
-
|
|
|
DPPC-d4 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in m
|
-
-
- HY-109506S3
-
|
|
|
DPPC-d9-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers . DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice .
|
-
-
- HY-112251S
-
|
|
|
D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-125853
-
|
Soybean phosphatidylcholine
|
|
Phospholipids
|
|
Phosphatidylcholines,soya is a phosphatidylcholine from soybean used in the preparation of liposomes. Phosphatidylcholines,soya can be used as a vehicle in animal agent administration .
|
-
- HY-142977
-
|
|
|
Phospholipids
|
|
6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate in the synthesis of ALC-0315. ALC-0315 is an ionizable amino lipid. ALC-0315 is a key component of LNP delivery vehicles. 6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an effective delivery vehicle of mRNA .
|
-
- HY-112251
-
D-Lin-MC3-DMA
Maximum Cited Publications
84 Publications Verification
|
|
Cationic Lipids
|
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
- HY-101103
-
|
(2-Hydroxypropyl)-β-cyclodextrin
|
|
Solubilizing Agents
|
|
HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability.
|
-
- HY-151511
-
|
|
|
Cationic Lipids
|
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
- HY-Y0683A
-
|
|
|
Bases
|
|
Petrolatum (white) is an ointment vehicle for many agents, due to its low skin irritation. Petrolatum (white) is a safe, effective wound care ointment for ambulatory surgery .
|
-
- HY-143210
-
|
|
|
Cationic Lipids
|
|
Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .
|
-
- HY-W145518
-
|
|
|
Emulsifiers
Thickeners
|
|
Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. Pectin involves in the formation of nanoparticles as a delivery vehicle of agents. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa .
|
-
- HY-W440727
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG-Vinylsulfone (MW 2000) is a thiol reactive polyPEG via thiol-ene reaction to form a thioether bond. It can self-assemble in water and is used to prepare liposome as drug vehicle for targeted delivery into tissues.
|
-
- HY-160581
-
|
|
|
Cationic Lipids
|
|
OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect .
|
-
- HY-138170
-
|
|
|
Cationic Lipids
|
|
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
|
-
- HY-155918
-
|
mPEG-Aldehyde (MW 1000)
|
|
Polymers
|
|
mPEG-CHO (MW 1000) participates in the formation of a three-dimensional porous scaffold that carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155920
-
|
mPEG-Aldehyde (MW 3400)
|
|
Polymers
|
|
mPEG-CHO (MW 3400) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155917
-
|
mPEG-Aldehyde (MW 750)
|
|
Polymers
|
|
mPEG-CHO (MW 750) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155922
-
|
mPEG-Aldehyde (MW 10000)
|
|
Polymers
|
|
mPEG-CHO (MW 10000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-W440883
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-155916
-
|
mPEG-Aldehyde (MW 550)
|
|
Polymers
|
|
mPEG-CHO (MW 550) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-B2247A
-
|
poly(lactic-co-glycolic acid) (75:25)
|
|
Polymers
|
|
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
|
-
- HY-155923
-
|
mPEG-Aldehyde (MW 20000)
|
|
Polymers
|
|
mPEG-CHO (MW 20000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155919
-
|
mPEG-Aldehyde (MW 2000)
|
|
Polymers
|
|
mPEG-CHO (MW 2000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155915
-
|
mPEG-Aldehyde (MW 350)
|
|
Polymers
|
|
mPEG-CHO (MW 350) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-155921
-
|
mPEG-Aldehyde (MW 5000)
|
|
Polymers
|
|
mPEG-CHO (MW 5000) participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.
|
-
- HY-154644
-
|
|
|
Emulsifiers
Solubilizing Agents
|
|
Soya Lecithin is a phospholipid mixture that can be used as a drug delivery vehicle and is a pharmaceutical excipient. Soya Lecithin can form a lipid bilayer structure through self-assembly, and its binding properties are amphiphilic (hydrophilic head and hydrophobic tail), encapsulating hydrophobic drugs. Soya Lecithin forms stable nanoliposomes or microemulsions, improves the solubility and cellular uptake efficiency of poorly soluble drugs (such as Curcumin (HY-N0005)), and exerts activities such as enhancing drug delivery and regulating cell proliferation .
|
-
- HY-138170A
-
|
|
|
Emulsifiers
Liposomal Film-forming Agents
|
|
ALC-0315 (Excipient, GMP Like) is the GMP Like class ALC-0315 (HY-138170), and can be used as pharmaceutical excipients. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 (Excipient, GMP Like) can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
