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Results for "

vesicular monoamine transporter 2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Monoamine Transporter (19) 5-HT Receptor (1) Autophagy (3) Drug Metabolite (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (5) Neurological Disease (16)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Monoamine Transporter Monoamine Oxidase VSV

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0590A

Tetrabenazine Racemate Ro 1-9569 Racemate	Monoamine Transporter	Neurological Disease
Tetrabenazine Racemate (Ro 1-9569 Racemate) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).

HY-117883

GZ-793A	Monoamine Transporter	Neurological Disease
GZ-793A is an orally active and selective vesicular monoamine transporter-2 (VMAT2) inhibitor, with an K_i of 0.029 μM. GZ-793A inhibits the neurochemical effects of methamphetamine (METH)-induced dopamine release. GZ-793A can be used for research of METH addiction .

HY-N0480

Reserpine 5 Publications Verification	Monoamine Transporter Autophagy	Neurological Disease Cancer
Reserpine is an inhibitor of the **vesicular monoamine transporter 2 (VMAT2**).

HY-N0480A

Reserpine hydrochloride 5 Publications Verification	Monoamine Transporter	Neurological Disease Cancer
Reserpine hydrochloride is an inhibitor of the **vesicular monoamine transporter 2 (VMAT2**).

HY-16771

Valbenazine 3 Publications Verification NBI-98854	Monoamine Transporter	Neurological Disease
Valbenazine (NBI-98854) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the K_i of 110-190 nM .

HY-N0480S

Reserpine-d9	Isotope-Labeled Compounds Monoamine Transporter Autophagy	Neurological Disease Cancer
Reserpine-d₉ is the deuterium labeled Reserpine. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).

HY-161433

VMAT2-IN-3	Monoamine Transporter	Neurological Disease
VMAT2-IN-3 (compound 10) is a potent vesicular monoamine transporter-2 (VMAT2) inhibitor with a K_i of 0.71 nM. VMAT2-IN-3 has the potential for neurological or psychiatric disease research .

HY-152171

GZ-11608	Monoamine Transporter	Neurological Disease
GZ-11608 is a potent and selective vesicular monoamine transporter-2 (VMAT2) inhibitor with high affinity (Ki = 25 nM). GZ-11608 decreases methamphetamine-induced dopamine release from isolated synaptic vesicles from brain dopaminergic neurons. GZ-11608 exhibits rapid brain penetration and without neurotoxicity. GZ-11608 can be used for the research of methamphetamine use disorder .

HY-120788

VMAT2-IN-4	Monoamine Transporter	Others
VMAT2-IN-4 (compound 11) is a vesicular monoamine transporter-2 (VMAT2) inhibitor. VMAT2-IN-4 inhibits [ ³H]-DTBZ binding (Ki = 560 nM). VMAT2-IN-4 inhibits [ ³H]-DA (Ki = 45 nM) from entering vesicles and being taken up by cells. VMAT2-IN-4 can be used in methamphetamine addiction research .

HY-16771A

Valbenazine tosylate NBI-98854 tosylate	Monoamine Transporter	Neurological Disease
Valbenazine tosylate (NBI-98854 tosylate) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the K_i of 110-190 nM .

HY-118990

Lobelane hydrochloride	Others	Neurological Disease
Lobelane hydrochloride is a biologically active compound that has the activity of inhibiting vesicular monoamine transporter-2 (VMAT2). Lobelane hydrochloride has a low affinity for nicotinic acetylcholine receptors (nAChR), thereby enhancing its selectivity for VMAT2. Synthetic structural changes of lobelane hydrochloride have led to some related analogs that show mild changes in affinity for VMAT2. The most potent synthetic lobelane hydrochloride obtained after structural modification has a K(i) value of 630 nM, showing significant VMAT2 selectivity. The biological activity of lobelane hydrochloride suggests that it has the potential to be used in the development of compounds to inhibit methamphetamine abuse .

HY-B0590S1

(+)-Tetrabenazine D6	Monoamine Transporter	Neurological Disease
(+)-Tetrabenazine-d₆ is the deuterium labeled (+)-Tetrabenazine. (+)-Tetrabenazine is a reversible inhibitor of vesicular monoamine transporter 2 (VMAT-2).

HY-N0480R

Reserpine (Standard)	Monoamine Transporter Autophagy	Neurological Disease Cancer
Reserpine (Standard) is the analytical standard of Reserpine. This product is intended for research and analytical applications. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).

HY-15793

NBI-98782 1 Publications Verification (+)-DTBZ; (+)-α-Dihydrotetrabenazine; (+)-α-DHTBZ	Monoamine Transporter	Neurological Disease
NBI-98782 is a high affinity and selectivity vesicular monoamine transporter 2 (VMAT2) inhibitor with a K_i of 3 nM. NBI-98782 has antipsychotic activity .

HY-B0590D

(-)-Tetrabenazine (-)-TBZ; (3S,11bS)-TBZ; (3S,11bS)-Tetrabenazine	Monoamine Transporter	Neurological Disease
(-)-Tetrabenazine ((-)-TBZ; compound 13) is an enantiomer of Tetrabenazine (HY-B0590). (+)-Tetrabenazine proves 3-fold more active than (-)-Tetrabenazine in inhibiting vesicular monoamine transporter 2 (VMAT2) .

HY-149170

FFN246	5-HT Receptor Monoamine Transporter	Neurological Disease
FFN246 is a fluorescent, dual substrate of *serotonin transporter* (SERT)** probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation .

HY-G0025

Tetrabenazine Metabolite (-)-β-Dihydrotetrabenazine; (-)-β-HTBZ	Monoamine Transporter Drug Metabolite	Neurological Disease
Tetrabenazine Metabolite is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a high affinity (K_i=13.4 nM) . Tetrabenazine Metabolite is be developed for the treatment of chorea associated with Huntington’s disease and other hyperkinetic disorders .

HY-B0590B

(+)-Tetrabenazine (+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine	Monoamine Transporter	Cancer
(+)-Tetrabenazine ((+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine) is a reversible inhibitor of vesicular monoamine transporter 2 (VMAT-2), inhibits transport by VMAT2 with 10-fold greater potency than transport by VMAT1.

HY-110334

FFN 206 dihydrochloride	Others	Others
FFN 206 dihydrochloride, a fluorescent probe, is used as an excellent Vesicular Monoamine Transporter 2 (VMAT2) substrate with an apparent K_m of 1.16 μM. FFN 206 dihydrochloride is capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles .

HY-103465

FFN511	Monoamine Transporter	Others
FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets *neuronal vesicular* monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2-containing membranes with an IC₅₀** of 1 µM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices .

HY-103465B

FFN511 hydrochloride	Monoamine Transporter	Others
FFN511 (hydrochloride) is a potent fluorescent false neurotransmitters (FFNs) that targets *neuronal vesicular* monoamine transporter 2 (VMA T2). FFN511 (hydrochloride) inhibits serotonin binding to VMA T2-containing membranes with an IC₅₀** of 1 µM. FFN511 (hydrochloride) directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0480

Reserpine 5 Publications Verification	Alkaloids Piperidine Alkaloids Structural Classification other families Neurological Disease Classification of Application Fields Anti-aging Source classification Plants Disease Research Fields Indole Alkaloids Cancer	Monoamine Transporter Autophagy
Reserpine is an inhibitor of the **vesicular monoamine transporter 2 (VMAT2**).

HY-N0480A

Reserpine hydrochloride 5 Publications Verification	Rauvolfia verticillata (Lour.) Baill. Apocynaceae Alkaloids Structural Classification Source classification Plants Indole Alkaloids	Monoamine Transporter
Reserpine hydrochloride is an inhibitor of the **vesicular monoamine transporter 2 (VMAT2**).

HY-N0480R

Reserpine (Standard)	Alkaloids Piperidine Alkaloids Structural Classification other families Source classification Plants Indole Alkaloids	Monoamine Transporter Autophagy
Reserpine (Standard) is the analytical standard of Reserpine. This product is intended for research and analytical applications. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).

Cat. No.	Product Name	Chemical Structure

HY-N0480S

Reserpine-d9
Reserpine-d₉ is the deuterium labeled Reserpine. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).

HY-B0590S1

(+)-Tetrabenazine D6
(+)-Tetrabenazine-d₆ is the deuterium labeled (+)-Tetrabenazine. (+)-Tetrabenazine is a reversible inhibitor of vesicular monoamine transporter 2 (VMAT-2).

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vesicular monoamine transporter 2

Inhibitors & Agonists

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Isotope-Labeled Compounds

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