2. Metabolic Enzyme/Protease
  3. E1/E2/E3 Enzyme
  4. SENP1-IN-3

SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement.

For research use only. We do not sell to patients.

SENP1-IN-3 Chemical Structure

SENP1-IN-3 Chemical Structure

CAS No. : 2416910-59-1

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Customer Review

Based on 1 publication(s) in Google Scholar

SENP1-IN-3 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

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Description

SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement[1].

IC50 & Target

SENP1[1]
In Vitro

SENP1-IN-3 improves the sensitivity of tumor cells to irradiation[1].
SENP1-IN-3 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC50 of >20μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SENP1-IN-3 Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: Hela cells
Concentration: 0.7 μM, 2.2 μM, 6.6 μM, 20 μM
Incubation Time: 72 hours
Result: IC50>20 μM
Molecular Weight

582.86

Formula

C36H58N2O4
CAS No.
SMILES

CC1(C)[C@@H](OC(C)=O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@](C(N(C)CC(NC)=O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SENP1-IN-3 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SENP1-IN-32416910-59-1E1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligasespecificdeSUMOylationproteaseSENP1tumorradiosensitivityenhancementradiosensitizersmallubiquitin-like modifierSUMOInhibitorinhibitorinhibit

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Cat. No.:
HY-134596
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