2. Anti-infection
  3. Bacterial
  4. SEQ-9

SEQ-9 is an orally active Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome inhibitor with an IC50 of approximately 170 nM for unmethylated Mtb ribosomes. SEQ-9 also potently inhibits A2296 methylated ribosomes. SEQ-9 can be used to study bacterial infection and drug resistance.

For research use only. We do not sell to patients.

SEQ-9 Chemical Structure

SEQ-9 Chemical Structure

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SEQ-9 Related Antibodies

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Description

SEQ-9 is an orally active Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome inhibitor with an IC50 of approximately 170 nM for unmethylated Mtb ribosomes. SEQ-9 also potently inhibits A2296 methylated ribosomes. SEQ-9 can be used to study bacterial infection and drug resistance[1].

Molecular Weight

1229.52

Formula

C60H100N4O20S
SMILES

C[C@H]([C@@]([C@@H]1C)([H])OC([C@H](C)[C@H]([C@@H]([C@H]([C@@H](C)C[C@@](OC(NC(C)(C)CNS(C2=CC=CC=C2)(=O)=O)=O)(C)C([C@@H]([C@@H]1OC(CC(C)C)=O)C)=O)O[C@]3([H])O[C@]([H])(C)C/C([C@H]3O)=N/OC)C)O[C@]4([H])O[C@@H](C)CN(C)[C@H](C)C4)=O)O[C@@]5([H])[C@H](OC)[C@H](OC)[C@H](O)[C@](C)([H])O5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SEQ-9 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SEQ-9SEQ9SEQ 9BacterialMtbinfectiondrug resistanceA2296Inhibitorinhibitorinhibit

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