2. Others GPCR/G Protein Neuronal Signaling Autophagy
  3. Isotope-Labeled Compounds 5-HT Receptor Dopamine Receptor Adrenergic Receptor Autophagy
  4. Sertindole-d4

Sertindole-d4 is the deuterium labeled Sertindole. Sertindole, a neuroleptic, is one of the newer antipsychotic medications available[1][2].

For research use only. We do not sell to patients.

Sertindole-d<sub>4</sub> Chemical Structure

Sertindole-d4 Chemical Structure

CAS No. : 1794737-42-0

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10 mg USD 1620 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Sertindole-d4:

Sertindole-d4 Related Antibodies

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α adrenergic receptor β adrenergic receptor

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Sertindole-d4 is the deuterium labeled Sertindole. Sertindole, a neuroleptic, is one of the newer antipsychotic medications available[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sertindole-d4 Related Antibodies
Molecular Weight

444.97

Formula

C24H22D4ClFN4O
CAS No.
Unlabeled CAS

106516-24-9
Appearance

Solid

Color

White to off-white

SMILES

ClC=1C=C2C(=CN(C2=CC1)C3=CC=C(F)C=C3)C4CCN(C(C(N5C(=O)NCC5)([2H])[2H])([2H])[2H])CC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMF : ≥ 15 mg/mL (33.71 mM)

DMF : ≥ 15 mg/mL (33.71 mM)

DMSO : ≥ 5 mg/mL (11.24 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 5 mg/mL (11.24 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF:PBS (pH 7.2)(1:3) : ≥ 0.25 mg/mL (0.56 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2473 mL 11.2367 mL 22.4734 mL
5 mM 0.4495 mL 2.2473 mL 4.4947 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO / DMF / DMF 1 mM 2.2473 mL 11.2367 mL 22.4734 mL 56.1836 mL
5 mM 0.4495 mL 2.2473 mL 4.4947 mL 11.2367 mL
10 mM 0.2247 mL 1.1237 mL 2.2473 mL 5.6184 mL
DMF / DMF 15 mM 0.1498 mL 0.7491 mL 1.4982 mL 3.7456 mL
20 mM 0.1124 mL 0.5618 mL 1.1237 mL 2.8092 mL
25 mM 0.0899 mL 0.4495 mL 0.8989 mL 2.2473 mL
30 mM 0.0749 mL 0.3746 mL 0.7491 mL 1.8728 mL
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Sertindole-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sertindole-d41794737-42-0Isotope-Labeled Compounds5-HT ReceptorDopamine ReceptorAdrenergic ReceptorAutophagySerotonin Receptor5-hydroxytryptamine ReceptorBeta ReceptorInhibitorinhibitorinhibit

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