2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. SR 16832

SR 16832 is a dual site covalent PPARγ inhibitor that acts at orthosteric and allosteric sites.

For research use only. We do not sell to patients.

SR 16832 Chemical Structure

SR 16832 Chemical Structure

CAS No. : 2088135-12-8

Size Price Stock Quantity
5 mg USD 80 In-stock
10 mg USD 128 In-stock
25 mg USD 250 In-stock
50 mg USD 400 In-stock
100 mg USD 640 In-stock
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Based on 1 publication(s) in Google Scholar

SR 16832 Related Antibodies

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View All PPAR Isoform Specific Products:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

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Description

SR 16832 is a dual site covalent PPARγ inhibitor that acts at orthosteric and allosteric sites[1].

IC50 & Target

PPARγ

 

Molecular Weight

357.75

Formula

C17H12ClN3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=CC=NC2=CC=C(OC)C=C12)C3=CC([N+]([O-])=O)=CC=C3Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (698.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7952 mL 13.9762 mL 27.9525 mL
5 mM 0.5590 mL 2.7952 mL 5.5905 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7952 mL 13.9762 mL 27.9525 mL 69.8812 mL
5 mM 0.5590 mL 2.7952 mL 5.5905 mL 13.9762 mL
10 mM 0.2795 mL 1.3976 mL 2.7952 mL 6.9881 mL
15 mM 0.1863 mL 0.9317 mL 1.8635 mL 4.6587 mL
20 mM 0.1398 mL 0.6988 mL 1.3976 mL 3.4941 mL
25 mM 0.1118 mL 0.5590 mL 1.1181 mL 2.7952 mL
30 mM 0.0932 mL 0.4659 mL 0.9317 mL 2.3294 mL
40 mM 0.0699 mL 0.3494 mL 0.6988 mL 1.7470 mL
50 mM 0.0559 mL 0.2795 mL 0.5590 mL 1.3976 mL
60 mM 0.0466 mL 0.2329 mL 0.4659 mL 1.1647 mL
80 mM 0.0349 mL 0.1747 mL 0.3494 mL 0.8735 mL
100 mM 0.0280 mL 0.1398 mL 0.2795 mL 0.6988 mL
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SR 16832 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SR 168322088135-12-8SR16832SR-16832PPARPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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