Substance P (5-11)

Cat. No.: HY-P3890: FAQs
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Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P (HY-P0201)), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor.

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Substance P (5-11) Chemical Structure

CAS No. : 51165-09-4

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Other Forms of Substance P (5-11):

Substance P (5-11) (TFA) Get quote

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Description	Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P (HY-P0201)), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor^[1].
In Vitro	When a fraction from rabbit brain enriched in glial cells was incubated with [³H]Substance P (5-11), an uptake of [3H]Substance P (5-11) is observed. When Substance P is released from nerve terminals, it is hydrolysed into Substance P (5-11), which is in turn accumulated into glial cells as well as nerve terminals and that this high affinity uptake mechanism may play an important role in terminating the synaptic action of Substance P^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Substance P (5-11) Related Antibodies
Molecular Weight	869.04
Formula	C₄₁H₆₀N₁₀O₉S
CAS No.	51165-09-4
Sequence	Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Sequence Shortening	QQFFGLM-NH2
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (258 KB) Handling Instructions (2659 KB)
References	[1]. A Inoue, et al. Active uptake system for substance P carboxy-terminal heptapeptide (5-11) into a fraction from rabbit enriched in glial cells. Jpn J Pharmacol. 1984 Oct;36(2):137-45. [Content Brief]

Substance P (5-11) Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Substance P (5-11)51165-09-4Neurokinin ReceptorNK receptorTachykinin receptorNeuropeptideNK-1heptapeptideInhibitorinhibitorinhibit

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