Terephthalic acid-d₄

Name: Terephthalic acid-d 4
Brand: MedChemExpress
SKU: HY-W010098S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W010098S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Terephthalic acid-d₄ is the deuterium labeled Terephthalic acid. Terephthalic acid is one isomer of the three phthalic, a precursor to the polyester PET, used to make clothing and plastic bottles.

For research use only. We do not sell to patients.

Terephthalic acid-d<sub>4</sub> Chemical Structure

Terephthalic acid-d₄ Chemical Structure

CAS No. : 60088-54-2

Size	Price	Stock	Quantity
50 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Terephthalic acid-d₄:

Terephthalic acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Terephthalic acid-d₄ is the deuterium labeled Terephthalic acid. Terephthalic acid is one isomer of the three phthalic, a precursor to the polyester PET, used to make clothing and plastic bottles.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

170.16

Formula

C₈H₂D₄O₄

CAS No.

60088-54-2

Unlabeled CAS

100-21-0

Appearance

Solid

Color

White to off-white

SMILES

OC(C1=C([2H])C([2H])=C(C([2H])=C1[2H])C(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 20 mg/mL (117.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8768 mL	29.3841 mL	58.7682 mL
5 mM	1.1754 mL	5.8768 mL	11.7536 mL
10 mM	0.5877 mL	2.9384 mL	5.8768 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Heck HD, et al. The induction of bladder stones by terephthalic acid, dimethyl terephthalate, and melamine (2,4,6-triamino-s-triazine) and its relevance to risk assessment. Regul Toxicol Pharmacol. 1985 Sep;5(3):294-313. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.8768 mL	29.3841 mL	58.7682 mL	146.9205 mL
	5 mM	1.1754 mL	5.8768 mL	11.7536 mL	29.3841 mL
	10 mM	0.5877 mL	2.9384 mL	5.8768 mL	14.6921 mL
	15 mM	0.3918 mL	1.9589 mL	3.9179 mL	9.7947 mL
	20 mM	0.2938 mL	1.4692 mL	2.9384 mL	7.3460 mL
	25 mM	0.2351 mL	1.1754 mL	2.3507 mL	5.8768 mL
	30 mM	0.1959 mL	0.9795 mL	1.9589 mL	4.8974 mL
	40 mM	0.1469 mL	0.7346 mL	1.4692 mL	3.6730 mL
	50 mM	0.1175 mL	0.5877 mL	1.1754 mL	2.9384 mL
	60 mM	0.0979 mL	0.4897 mL	0.9795 mL	2.4487 mL
	80 mM	0.0735 mL	0.3673 mL	0.7346 mL	1.8365 mL
	100 mM	0.0588 mL	0.2938 mL	0.5877 mL	1.4692 mL