2. Neuronal Signaling
  3. Amyloid-β
  4. Tramiprosate-d6

Tramiprosate-d6  (Synonyms: Homotaurine-d6; 3-Amino-1-propanesulfonic acid-d6)

Cat. No.: HY-14602S Purity: ≥98.0%
SDS COA Handling Instructions

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Tramiprosate-d6 is the deuterium labeled Tramiprosate. Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects[1][2][3].

For research use only. We do not sell to patients.

Tramiprosate-d<sub>6</sub> Chemical Structure

Tramiprosate-d6 Chemical Structure

CAS No. : 1131576-06-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 198 In-stock
Solution
10 mM * 1 mL in Water USD 198 In-stock
Solid
1 mg USD 85 In-stock
5 mg USD 180 In-stock
10 mg USD 300 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Tramiprosate-d6:

Tramiprosate-d6 Related Antibodies

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Description

Tramiprosate-d6 is the deuterium labeled Tramiprosate. Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tramiprosate-d6 Related Antibodies
Molecular Weight

145.21

Formula

C3H3D6NO3S
CAS No.
Unlabeled CAS

3687-18-1
Appearance

Solid

Color

White to off-white

SMILES

O=S(C([2H])([2H])C([2H])([2H])C([2H])([2H])N)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (344.33 mM; ultrasonic and warming and heat to 60°C)

H2O : 50 mg/mL (344.33 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8866 mL 34.4329 mL 68.8658 mL
5 mM 1.3773 mL 6.8866 mL 13.7732 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

SDS (252 KB)

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 6.8866 mL 34.4329 mL 68.8658 mL 172.1644 mL
5 mM 1.3773 mL 6.8866 mL 13.7732 mL 34.4329 mL
10 mM 0.6887 mL 3.4433 mL 6.8866 mL 17.2164 mL
15 mM 0.4591 mL 2.2955 mL 4.5911 mL 11.4776 mL
20 mM 0.3443 mL 1.7216 mL 3.4433 mL 8.6082 mL
25 mM 0.2755 mL 1.3773 mL 2.7546 mL 6.8866 mL
30 mM 0.2296 mL 1.1478 mL 2.2955 mL 5.7388 mL
40 mM 0.1722 mL 0.8608 mL 1.7216 mL 4.3041 mL
50 mM 0.1377 mL 0.6887 mL 1.3773 mL 3.4433 mL
60 mM 0.1148 mL 0.5739 mL 1.1478 mL 2.8694 mL
80 mM 0.0861 mL 0.4304 mL 0.8608 mL 2.1521 mL
100 mM 0.0689 mL 0.3443 mL 0.6887 mL 1.7216 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Tramiprosate-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tramiprosate-d61131576-06-1Homotaurine-d63-Amino-1-propanesulfonic acid-d6Amyloid-ββ-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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